Organism Overview: Providencia siddallii


 
lpdA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0001Dihydrolipoyl dehydrogenase.
aceF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0002Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, partial; Missing 2 Biotin-requiring enzyme domains; One domain suffices with respect to enzyme activity [...]
aceE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0003Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
nadC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0004Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family.
coaE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0005Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
secA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0006Protein translocase subunit SecA, partial; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of A [...]
CRK85453.1 protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0007Putative protein of unknown function (DUF721) family protein; Predicted based upon partial overlap to PFAM DUF721and similarity to related proteins in nr.
lpxC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0008UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosaminedeacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed ste [...]
ftsZ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0009Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the tim [...]
ftsA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0010Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
ftsQ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0011Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins [...]
ddlB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0012D-alanine--D-alanine ligase B; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
murC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0013UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
murG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0014Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid interme [...]
ftsW protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0015Lipid II flippase FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
murD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0016UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF [...]
mraY protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0017Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY s [...]
murF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0018UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanineligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murei [...]
murE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0019UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelateligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UM [...]
ftsI protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0020Peptidoglycan synthase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
ftsL protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0021Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins [...]
rsmH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0022Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
ygdQ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0023UPF0053 inner membrane protein YgdQ; Integral membrane TerC family protein.
speB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0024Agmatinase; Belongs to the arginase family.
speA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0025Biosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
metK protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0026S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formati [...]
gyrA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0027DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
nrdG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0028Anaerobic ribonucleoside-triphosphate reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radic [...]
nrdD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0029Anaerobic ribonucleoside-triphosphate reductase.
pyrI protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0030Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase.
pyrB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0031Aspartate carbamoyltransferase catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
epmA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0032Elongation factor P--(R)-beta-lysine ligase; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P). Catalyzes the ATP [...]
talB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0033Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
dnaK protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0034Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
dnaJ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0035Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an [...]
rpsT protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_003630S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
ribF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0037Riboflavin biosynthesis protein RibF; Belongs to the ribF family.
ileS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0038Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such err [...]
lspA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0039Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
ispH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_00404-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethyl [...]
dapB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_00414-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
carA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0042Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.
carB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0043Carbamoyl-phosphate synthase large chain; Belongs to the CarB family.
ibpA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0044Small heat shock protein IbpA; Belongs to the small heat shock protein (HSP20) family.
groS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_004510 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
groL protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_004660 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
epmB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0047BL-lysine 2,3-aminomutase, partial; 3' end; 5'-end is gene SOFFGTOCOR_0047A; 5'-end shortened because of an early stop codon; Radical_SAM, Fer4_14 domains intact.
efp protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0048Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by [...]
frdD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0049Fumarate reductase subunit D; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.
frdC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0050Fumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.
frdB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0051Fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
frdA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0052Fumarate reductase flavoprotein subunit; Shortened 3'-end.
tpiA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0053Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the [...]
trkH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0054Trk system potassium uptake protein TrkH; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.
pepQ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0055Xaa-Pro dipeptidase; Splits dipeptides with a prolyl residue in the C-terminal position.
rmuC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0056Putative DNA recombination protein RmuC.
yabI protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0057Putative inner membrane protein YabI.
rne protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0058Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation [...]
rluC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0059Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
rpmF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_006050S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
plsX protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0061Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but n [...]
fabH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_00623-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first c [...]
fabD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0063Malonyl CoA-acyl carrier protein transacylase.
fabG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_00643-oxoacyl-[acyl-carrier-protein] reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongati [...]
acpP protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0066Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
pabC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0067Aminodeoxychorismate lyase.
yceG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0068UPF0755 protein YceG; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
tmk protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0069Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
holB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0070DNA polymerase III subunit delta'.
ycfH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0071Uncharacterized deoxyribonuclease YcfH.
hinT protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0072HIT-like protein HinT.
mfd protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0073Transcription-repair-coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated tr [...]
lolC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0074Lipoprotein-releasing system transmembrane protein LolC.
lolD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0075Lipoprotein-releasing system ATP-binding proteinLolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.
lolE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0076Lipoprotein-releasing system transmembrane protein LolE.
purB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0077Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
mnmA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0078tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step o [...]
folB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0079Dihydroneopterin aldolase.
folA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0080Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
apaH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0081Bis(5'-nucleosyl)-tetraphosphatase [symmetrical]; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
rsmA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0082Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S part [...]
pdxA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_00834-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decar [...]
surA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0084Chaperone SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, whic [...]
lptD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0085LPS-assembly protein LptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
lgt protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0087Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
thyA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0088Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate ( [...]
htrB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0089Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
zipA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0090Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also req [...]
der protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0091GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
bamB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0092Outer membrane protein assembly factor BamB; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
yfgM protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0093UPF0070 protein YfgM.
hisS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0094Histidine--tRNA ligase.
ispG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_00954-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG fa [...]
rodZ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0096Cytoskeleton protein RodZ.
rlmN protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0097Dual-specificity RNA methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial rol [...]
pepB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0098Peptidase B; Probably plays an important role in intracellular peptide degradation.
ligA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0099DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy sourc [...]
gltX protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0100Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of [...]
pgk protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0104Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
fbaA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0105Fructose-bisphosphate aldolase class 2; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bis [...]
gdhA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0106NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
uspA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0107Universal stress protein A.
pitA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0108Low-affinity inorganic phosphate transporter 1.
pckA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0109Phosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between th [...]
nudE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0110ADP compounds hydrolase NudE.
mrcA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0111Penicillin-binding protein 1A.
aroK protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0112Shikimate kinase 1; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
aroB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_01133-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
rpe protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0114Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
trpS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0115Tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
sodA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0116Superoxide dismutase [Mn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
grxA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0117Glutaredoxin-1.
gloB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0118Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
hha protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0119Hemolysin expression-modulating protein Hha.
ppiD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0121Peptidyl-prolyl cis-trans isomerase D.
lon protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0122Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular home [...]
clpX protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0123ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in th [...]
clpP protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0124ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degrada [...]
yajG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0125Uncharacterized lipoprotein YajG.
panE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_01262-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
thiI protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0127tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the tran [...]
xseB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0128Exodeoxyribonuclease 7 small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleo [...]
ispA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0129Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
dxs protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_01301-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (D [...]
pgpA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0131Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
thiL protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0132Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thi [...]
nusB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0133N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of t [...]
ribE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_01346,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. [...]
ribD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0135Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-termi [...]
nrdR protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0136Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
ahpC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0137Alkyl hydroperoxide reductase subunit C.
fbp protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0138Fructose-1,6-bisphosphatase class 1; Belongs to the FBPase class 1 family.
ppa protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0139Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
tamB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0140Translocation and assembly module TamB.
tamA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0141Translocation and assembly module TamA.
folD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0143Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahy [...]
cysS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0144Cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
lpxH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0145UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water [...]
purE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0146N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
purK protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0147N5-carboxyaminoimidazole ribonucleotide synthase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosy [...]
ybhI protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0148Inner membrane protein YbhI.
kdsD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0149Arabinose 5-phosphate isomerase KdsD.
kdsC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_01503-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phos [...]
lptC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0151Lipopolysaccharide export system protein LptC; Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Belongs to the LptC family.
lptA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0152Lipopolysaccharide export system protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form [...]
lptB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0153Lipopolysaccharide export system ATP-binding protein LptB.
yhbJ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0154UPF0042 nucleotide-binding protein YhbJ; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concen [...]
mreD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0156Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.
CRK85597.1 protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0157Cell shape-determining protein MreC; Involved in formation and maintenance of cell shape.
mreB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0158Rod shape-determining protein MreB.
aroQ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_01593-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
accB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0160Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the c [...]
accC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0161Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarbox [...]
fis protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0162DNA-binding protein Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.
mdh protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0163Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
ispB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0164Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
rplU protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_016550S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
rpmA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_016650S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
obgE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0167GTPase ObgE/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in [...]
greA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0168Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trappi [...]
rlmE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0169Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
ftsH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0170ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral memb [...]
folP protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0171Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate [...]
glmM protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0172Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
secG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0173Protein-export membrane protein SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
nusA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0176Transcription termination/antitermination protein NusA; Participates in both transcription termination and antitermination.
infB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0177Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...]
rbfA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0178Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
truB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0179tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
rpsO protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_018030S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
pnp protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0181Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
nlpI protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0182Lipoprotein NlpI; May be involved in cell division.
deaD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0183ATP-dependent RNA helicase DeaD; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
pabA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0184Aminodeoxychorismate synthase component 2.
engB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0185Probable GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. E [...]
dsbA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0186Thiol:disulfide interchange protein DsbA.
gor protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0187Glutathione reductase.
yhjJ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0188Protein YhjJ; Shortened 3'-end.
glyS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0189Glycine--tRNA ligase beta subunit.
glyQ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0190Glycine--tRNA ligase alpha subunit.
pgm protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0191Phosphoglucomutase.
serC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0192Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belon [...]
aroA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_01933-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl [...]
cmk protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0194Cytidylate kinase.
rpsA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_019530S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
ihfB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0196Integration host factor subunit beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in tran [...]
msbA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0197Lipid A export ATP-binding/permease protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) [...]
lpxK protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0198Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis [...]
kdsB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_01993-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
ycbL protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0200Uncharacterized protein YcbL.
aspC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0201Aspartate aminotransferase.
ompF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0202Outer membrane protein F.
asnS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0203Asparagine--tRNA ligase.
ytfB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0204Putative uncharacterized protein YtfB; Predicted based upon similarity to PFAM OapA and related proteins in nr; Shortened 5'-end; No detectable OapA_N motif.
rplI protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_020550S ribosomal protein L9; Binds to the 23S rRNA.
rpsR protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_020630S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosom [...]
rpsF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_020730S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
rlmB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_020823S rRNA (guanosine-2'-O-)-methyltransferase RlmB; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
purA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0209Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to t [...]
hflC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0210Modulator of FtsH protease HflC; HflC and HflK could regulate a protease.
hflK protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0211Modulator of FtsH protease HflK; HflC and HflK could encode or regulate a protease.
miaA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0212tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(di [...]
orn protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0214Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
psd protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0215Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
mscM protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0216Miniconductance mechanosensitive channel MscM.
pgsA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0217CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
fabV protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0220Trans-2-enoyl-CoA reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety t [...]
lolB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0221Outer-membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
ispE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_02224-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. I [...]
prs protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0223Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hy [...]
pth protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0224Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
ychF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0225Ribosome-binding ATPase YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
prfA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0226Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
prmC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0227Release factor glutamine methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; B [...]
kdsA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_02282-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family.
murJ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0230Probable peptidoglycan biosynthesis protein MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic [...]
argS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0231Arginine--tRNA ligase.
aspS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0232Aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor en [...]
znuB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0233BHigh-affinity zinc uptake system membrane protein ZnuB, partial; 3' end; 5'-end is gene SOFFGTOCOR_0233A; Shortened 5'end; ABC-3 HMM almost complete, missing 13 residues; Unknown if pseudogene.
znuC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0234Zinc import ATP-binding protein ZnuC; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter s [...]
znuA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0235High-affinity zinc uptake system protein ZnuA; Belongs to the bacterial solute-binding protein 9 family.
pykA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0236Pyruvate kinase II; Belongs to the pyruvate kinase family.
tsaB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0237tRNA threonylcarbamoyladenosine biosynthesis protein TsaB.
mltB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0238Membrane-bound lytic murein transglycosylase B; Unknown EC_number=4.2.2.n1.
hrpA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0239ATP-dependent RNA helicase HrpA, partial.
ydgI protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0240Putative arginine/ornithine antiporter.
pntA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0241NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the [...]
pntB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0242NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the [...]
clpB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0244BChaperone protein ClpB, partial; 3' end; Partial 5'-end is gene SOFFGTOCOR_0244A; Shortened 5'-end; In E.coli, a natural shorter version of the protein has been detected and expression of both th [...]
rluD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0245Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
bamD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0246Outer membrane protein assembly factor BamD; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Cons [...]
rplS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_024750S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
trmD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0248tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rpsP protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_025030S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
ffh protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0251Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nasce [...]
luxS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0252S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the en [...]
gshA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0253Glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
csrA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0256Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid g [...]
alaS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0257Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA( [...]
proA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0258Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclizat [...]
proB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0259Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
nqrF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0262Na(+)-translocating NADH-quinone reductase subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from t [...]
nqrE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0263Na(+)-translocating NADH-quinone reductase subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from t [...]
nqrD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0264Na(+)-translocating NADH-quinone reductase subunit D; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from t [...]
nqrC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0265Na(+)-translocating NADH-quinone reductase subunit C; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from t [...]
nqrB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0266Na(+)-translocating NADH-quinone reductase subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from t [...]
nqrA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0267Na(+)-translocating NADH-quinone reductase subunit A; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from t [...]
gmhA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0268Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
fpr protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0269Ferredoxin--NADP reductase.
menA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_02701,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
hslU protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0271ATP-dependent protease ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU [...]
hslV protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0272ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
priA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0274Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its h [...]
rpmE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_027550S ribosomal protein L31; Binds the 23S rRNA.
ihfA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0276Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in tra [...]
pheT protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0277Phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
pheS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0278Phenylalanine--tRNA ligase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
rplT protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_027950S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing func [...]
rpmI protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_028050S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
infC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0281Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enha [...]
thrS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0282Threonine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family.
ydjM protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0283Inner membrane protein YdjM.
mgtA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0284Magnesium-transporting ATPase, P-type 1.
cspC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0285Cold shock-like protein CspC.
pyrC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0287Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
yfhL protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0289Uncharacterized ferredoxin-like protein YfhL; Shortened 3'-end; Fer4_10 domain almost intact, missing 5 residues.
acpS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0290Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
pdxj protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0291Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amin [...]
era protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0292GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cyc [...]
rnc protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0293Ribonuclease 3; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRN [...]
lepB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0294Signal peptidase I; Belongs to the peptidase S26 family.
lepA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0295Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon bac [...]
nadB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0296L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
ung protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0297Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
grpE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0298Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleot [...]
nadK protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0299NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of [...]
bamE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0300Outer membrane protein assembly factor BamE; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
ratB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0301UPF0125 protein RatB; Belongs to the UPF0125 (RnfH) family.
smpB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0302SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tm [...]
fieF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0304Putative ferrous-iron efflux pump FieF; Predicted based upon similarity to PFAM Cation_efflux and related proteins in nr; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) [...]
lysU protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0305Lysine--tRNA ligase, heat inducible; Belongs to the class-II aminoacyl-tRNA synthetase family.
prfB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0306Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
cptB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0307Antitoxin CptB; Shortened 3'-end; Sdh5 domain almost intact, missing 8 residues; Unknown if pseudogene.
rho protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0308Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
wecA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0309Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C [...]
wzzE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0310Lipopolysaccharide biosynthesis protein WzzE.
wecB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0311UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
wecC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0312UDP-N-acetyl-D-mannosamine dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
rffG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0313dTDP-glucose 4,6-dehydratase 2; Shortened 3'-end; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
rmlA2 protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0314Glucose-1-phosphate thymidylyltransferase 2; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thym [...]
wecD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0315WecD protein; dTDP-fucosamine acetyltransferase.
rffA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0316dTDP-4-amino-4,6-dideoxygalactose transaminase; Belongs to the DegT/DnrJ/EryC1 family.
wzxE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0317Protein WzxE.
wecF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0318TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase.
wzyE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0319Putative ECA polymerase.
wecG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0320UDP-N-acetyl-D-mannosaminuronic acid transferase; Belongs to the glycosyltransferase 26 family.
yifK protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0321Probable transport protein YifK.
cyaA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0325Adenylate cyclase, partial; 5' end; Shortened 3'-end; Adenyl_cycl_N domain intact; Lacking most of Adenylate_cycl domain. In E. coli, A truncated version of this gene, similar to what is observed [...]
ssb protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0326Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of act [...]
alr protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0327Alanine racemase, biosynthetic; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
dnaB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0328Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DN [...]
qorA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0329Quinone oxidoreductase 1.
nnrD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0330ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which cataly [...]
rsmD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0331Ribosomal RNA small subunit methyltransferase D; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD [...]
ftsY protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0332Signal recognition particle receptor FtsY, partial; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by th [...]
ftsE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0333Cell division ATP-binding protein FtsE.
rpoH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0335RNA polymerase sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is invol [...]
deoB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0336Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
holD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0337DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuc [...]
pyrD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0338Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfami [...]
fabA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_03393-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-deceno [...]
tusE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0340Sulfurtransferase TusE; Part of a sulfur-relay system.
uspG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0342Universal stress protein G.
mscS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0343ASmall-conductance mechanosensitive channel, partial; 5' end; 3'-end is gene SOFFGTOCOR_0343B; 3'-end shortened by 12 aminoacids.
rpiA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0344Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
ygfA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0345Uncharacterized protein YgfA; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
zapA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0346Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation [...]
yqjA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0348Inner membrane protein YqjA.
rsmI protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0350Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
lpoA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0351Putative penicillin-binding protein activator LpoA; Shortened 5'-end; Apparently LppC family HMM not intact; Unknown if pseudogene.
yraP protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0352Uncharacterized protein YraP.
serS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0355Serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further co [...]
infA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0358Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
ftnA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0359Ferritin-1; Iron-storage protein.
htpX protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0360Protease HtpX.
xthA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0361Exodeoxyribonuclease III.
hns protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0362DNA-binding protein H-NS; Belongs to the histone-like protein H-NS family.
clsA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0363Cardiolipin synthase A; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
sppA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0364Protease 4.
gapA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0365Glyceraldehyde-3-phosphate dehydrogenase A; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
prc protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0366Tail-specific protease; Belongs to the peptidase S41A family.
proQ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0367ProP effector; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belon [...]
pabB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0368Aminodeoxychorismate synthase component 1.
glnA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0369Glutamine synthetase.
dapD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_03702,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.
map protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0371Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharg [...]
rpsB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_037230S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
tsf protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0373Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the [...]
pyrH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0374Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
frr protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0375Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
dxr protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_03761-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP).
ispU protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0377Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate [...]
cdsA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0378Phosphatidate cytidylyltransferase.
rseP protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0379Regulator of sigma-E protease RseP.
bamA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0380Outer membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Cons [...]
skp protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0381Chaperone protein Skp; Belongs to the skp family.
lpxD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0382UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved [...]
fabZ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_03833-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated an [...]
lpxA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0384Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamineO-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membr [...]
lpxB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0385Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid t [...]
dnaE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0386DNA polymerase III subunit alpha; Shortened 3'-end.
accA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0387Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on [...]
tilS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0388tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is c [...]
proS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0389Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA( [...]
gmhB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0390D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase.
pssA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0391CDP-diacylglycerol--serine O-phosphatidyltransferase.
yegQ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0392Uncharacterized protease YegQ.
thiD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0393Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
soxS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0394Regulatory protein SoxS.
guaA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0395GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
guaB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0396Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesi [...]
xseA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0397Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleo [...]
ptrB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0398Protease 2.
maeB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0399NADP-dependent malic enzyme.
dapE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0400Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in [...]
purC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0401Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family.
dapA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_04034-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
bcp protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0404Putative peroxiredoxin bcp.
perM protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0405Putative permease PerM.
purM protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0406Phosphoribosylformylglycinamidine cyclo-ligase.
purN protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0407Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylg [...]
ppk protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0408Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
murI protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0409Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
murB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0410UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
birA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0411Bifunctional ligase/repressor BirA, partial; 3'-end; Shortened 5'-end; In E. coli, an N-termial deletion mutant (aminoacids 65-321) was detected to have lost the DNA binding activity but retained [...]
coaA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0412Pantothenate kinase.
tufB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0417Elongation factor Tu 2; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
rpsJ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_041830S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
rplC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_041950S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rplD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_042050S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
rplW protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_042150S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main dock [...]
rplB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_042250S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It [...]
rpsS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_042330S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplV protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_042450S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wal [...]
rpsC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_042530S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplP protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_042650S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpmC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_042750S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
rpsQ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_042830S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rplN protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_042950S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rplX protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_043050S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
rplE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_043150S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [...]
rpsN protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_043230S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the un [...]
rpsH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_043330S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to [...]
rplF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_043450S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the t [...]
rplR protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_043550S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protubera [...]
rpsE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_043630S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 fam [...]
rpmD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_043750S ribosomal protein L30.
rplO protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_043850S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
secY protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0439Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the [...]
rpmJ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_044050S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.
rpsM protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_044130S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 [...]
rpsK protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_044230S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belon [...]
rpsD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_044330S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpoA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0444DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplQ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_044550S ribosomal protein L17.
trkA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0446Trk system potassium uptake protein TrkA.
fmt protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0447Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
def protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0448Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...]
aroE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0450Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshiki [...]
gmk protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0453Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
rpoZ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0454ADNA-directed RNA polymerase subunit omega, partial; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the bet [...]
spoT protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0455Bifunctional (p)ppGpp synthase/hydrolase SpoT; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activi [...]
fumC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0456Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily [...]
nth protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0458Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- [...]
rnb protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0459Exoribonuclease 2; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
pyrF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0460Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamil [...]
pgpB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0461Phosphatidylglycerophosphatase B.
ribA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0462GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
pepO protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0463Neutral endopeptidase.
sohB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0464Probable protease SohB.
yciK protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0465Uncharacterized oxidoreductase YciK.
mepS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0466Murein DD-endopeptidase MepS/Murein LD-carboxypeptidase.
menE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_04682-succinylbenzoate--CoA ligase.
menC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0469BO-succinylbenzoate synthase, partial; 3' end; 5'-end is gene SOFFGTOCOR_0469A; Shortened 5'-end; Intact MR_MLE domain; Unknown if pseudogene.
menB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_04701,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
menD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_04712-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylatesynthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resultin [...]
menF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0472Menaquinone-specific isochorismate synthase.
nuoN protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0473NADH-quinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoM protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0474NADH-quinone oxidoreductase subunit M.
nuoL protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0475NADH-quinone oxidoreductase subunit L.
nuoK protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0476NADH-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoJ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0477NADH-quinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton trans [...]
nuoI protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0478NADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0479NADH-quinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0480NADH-quinone oxidoreductase subunit G; Belongs to the complex I 75 kDa subunit family.
nuoF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0481NADH-quinone oxidoreductase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit fa [...]
nuoE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0482NADH-quinone oxidoreductase subunit E.
nuoC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0483NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the [...]
nuoB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0484NADH-quinone oxidoreductase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0485NADH-quinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
ackA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0486Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
pta protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0487Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
purF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0488Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine p [...]
cvpA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0489Colicin V production protein; Shortened 3' end.
folC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0490Bifunctional protein FolC; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or [...]
accD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0491Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its [...]
truA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0492tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
pdxB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0493Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
mltC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0495Membrane-bound lytic murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.
trmB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0496tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB f [...]
proC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0497Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
yggS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0498UPF0001 protein YggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
yqgF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0499Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
yqgE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0500UPF0301 protein YqgE; Belongs to the UPF0301 (AlgH) family.
gshB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0501Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
tsaD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0502tRNA N6-adenosine threonylcarbamoyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is [...]
rpsU protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_050330S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
dnaG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0504BDNA primase, partial; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
rpoD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0505RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the p [...]
crp protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0506cAMP-activated global transcriptional regulator CRP.
thiH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_05072-iminoacetate synthase.
thiG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0508Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of th [...]
thiS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0509Sulfur carrier protein ThiS.
thiF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0510Sulfur carrier protein ThiS adenylyltransferase.
thiE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0511Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monopho [...]
thiC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0512Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methioni [...]
rpsL protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_051330S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S an [...]
rpsG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_051430S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit inte [...]
fusA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0515Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- [...]
secE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0516Protein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belon [...]
rplA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_051750S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplJ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_051850S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal prot [...]
rplL protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_051950S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the ba [...]
nusG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0520Transcription termination/antitermination protein NusG; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elong [...]
rplK protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_052150S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
rpoB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0522DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0523DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
adk protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0524Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
htpG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0525Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.
ybaB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0526Nucleoid-associated protein YbaB; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
dnaX protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0527DNA polymerase III subunit tau, gamma isoform; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits [...]
CRK85935.1 protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0528Sodium:sulfate symporter transmembrane region family protein.
eno protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0529Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
pyrG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0530CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the fo [...]
mtnN protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_05325'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) [...]
dksA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0533RNA polymerase-binding transcription factor DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive [...]
pcnB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0534Poly(A) polymerase I; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influenc [...]
folK protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_05352-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase.
panB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_05363-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to [...]
panC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0537Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
rnhA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0538Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
tktA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0539Transketolase 1; Belongs to the transketolase family.
dnaQ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0540DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing funct [...]
recC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0541RecBCD enzyme subunit RecC; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidi [...]
amiC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0542N-acetylmuramoyl-L-alanine amidase AmiC.
dapF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0543Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of t [...]
yigB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0544Flavin mononucleotide phosphatase YigB.
ybdN protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0545Uncharacterized protein YbdN.
lipA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0546Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, there [...]
lipB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0547Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also ac [...]
bioD1 protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0552ATP-dependent dethiobiotin synthetase BioD 1; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid [...]
bioC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0553Malonyl-[acyl-carrier protein] O-methyltransferase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). [...]
bioF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_05548-amino-7-oxononanoate synthase.
bioB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0555Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily [...]
bioA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0556Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8 [...]
gpmA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_05572,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- depende [...]
nadA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0558Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
ybgF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0559Uncharacterized protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.
pal protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0560Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
tolB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0561Protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key int [...]
tolA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0562Protein TolA.
tolR protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0563Protein TolR.
tolQ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0564Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, fo [...]
sucD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0565Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP an [...]
sucC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0566Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and [...]
sucB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0567Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex.
sucA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_05682-oxoglutarate dehydrogenase E1 component.
ybgI protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0570Putative GTP cyclohydrolase 1 type 2.
glnS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0571Glutamine--tRNA ligase.
miaB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0575tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosin [...]
ybeY protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0576Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
corC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0577Magnesium and cobalt efflux protein CorC.
lnt protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0578Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrol [...]
leuS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0579Leucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
lptE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0580LPS-assembly lipoprotein LptE; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LP [...]
holA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0581DNA polymerase III subunit delta.
nadD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0582Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
mrdA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0583Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
mrdB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0584Rod shape-determining protein MrdB; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
gpsA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0585Glycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
tdh protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0586L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.
kbl protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_05872-amino-3-ketobutyrate coenzyme A ligase.
hldD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0588ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the [...]
rfaC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0589Lipopolysaccharide heptosyltransferase 1.
waaA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_05903-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV( [...]
coaD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0591Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD [...]
rpmG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_059250S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
rpmB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_059350S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
coaBC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0594Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopan [...]
dut protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0595Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intrace [...]
pyrE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0596Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
plsC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_05971-acyl-sn-glycerol-3-phosphate acyltransferase; Unknown EC_number=2.3.1.n4; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
cca protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0598Multifunctional CCA protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order [...]
hldE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0599Bifunctional protein HldE; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to t [...]
ribB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_06003,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
cutA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0601Putative divalent-cation tolerance protein CutA; Predicted based upon similarity to PFAM CutA1 and related proteins in nr.
CRK86001.1 protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0602Putative Invasin; Predicted based upon similarity to PFAM DUF3442, Big_1, DUF4480 and related proteins in nr.
mnmE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0603tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
yidC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0604Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane pro [...]
rnpA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0605Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. [...]
rpmH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_060650S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
dnaA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0607Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically doub [...]
dnaN protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0608DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadin [...]
gyrB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0609DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
asd protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0610Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family.
uvrD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0612DNA helicase II.
ispF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_06132-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid [...]
ispD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_06142-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to [...]
ftsB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0615Cell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins [...]
purH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0616Bifunctional purine biosynthesis protein PurH.
purD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0617Phosphoribosylamine--glycine ligase; Belongs to the GARS family.
rplY protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_061850S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 fa [...]
bioH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0619Pimeloyl-[acyl-carrier protein] methyl ester esterase; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesiz [...]
recB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0620RecBCD enzyme subunit RecB; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidi [...]
nlpD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0621Murein hydrolase activator NlpD.
metG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0622Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
dcd protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0623Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.
yegH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0624UPF0053 protein YegH.
tadA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0625tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
purL protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0626Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ri [...]
nadE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0627NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
glyA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0628Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
glmS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0629Glutamine--fructose-6-phosphate aminotransferase[isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
glmU protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0630Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer [...]
mnmG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0631tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
lysC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0633Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family.
pgi protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0634Glucose-6-phosphate isomerase; Belongs to the GPI family.
plsB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0635Glycerol-3-phosphate acyltransferase; Belongs to the GPAT/DAPAT family.
ybdM protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0636Uncharacterized protein YbdM.
suhB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0637Inositol-1-monophosphatase.
iscS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0638Cysteine desulfurase IscS; Shortened 3'-end.
fabB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_06393-oxoacyl-[acyl-carrier-protein] synthase 1; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
aroC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0640Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
prmB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_064150S ribosomal protein L3 glutamine methyltransferase; Belongs to the protein N5-glutamine methyltransferase family.
valS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0642Valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, [...]
holC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0643DNA polymerase III subunit chi.
lptF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0644Lipopolysaccharide export system permease protein LptF.
lptG protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0645Lipopolysaccharide export system permease protein LptG.
ampH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0646D-alanyl-D-alanine- carboxypeptidase/endopeptidaseAmpH.
yrbA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0648Uncharacterized protein YrbA; Belongs to the BolA/IbaG family.
murA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0649UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
degQ protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0650Periplasmic pH-dependent serine endoprotease DegQ; Belongs to the peptidase S1C family.
yhcB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0651Inner membrane protein YhcB; Shortened 3'-end; Almost intact DUF1043 family HMM.
rplM protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_065250S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages [...]
rpsI protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_065330S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
aroH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0654Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptuloson [...]
sufA protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0655Protein SufA; Belongs to the HesB/IscA family.
sufB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0656FeS cluster assembly protein SufB.
sufC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0657Probable ATP-dependent transporter SufC.
sufD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0658FeS cluster assembly protein SufD.
sufS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0659Cysteine desulfurase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomo [...]
sufE protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0660Cysteine desulfuration protein SufE.
mdtK protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0662Multidrug resistance protein MdtK.
ribC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0663Riboflavin synthase.
grxD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0665Glutaredoxin-4; Belongs to the glutaredoxin family. Monothiol subfamily.
rnt protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0666Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP [...]
pdxH protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0666APyridoxamine 5'-phosphate oxidase, partial; 5' end; 3' end is gene SOFFGTOCOR_0666B; Pyridox_oxidase domain intact; missing PNPOx_C domain.
tyrS protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0667Tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tR [...]
sapF protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0668Peptide transport system ATP-binding protein SapF; Shortened 3'-end.
sapD protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0669Peptide transport system ATP-binding protein SapD; Belongs to the ABC transporter superfamily.
sapC protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0670Peptide transport system permease protein SapC.
sapB protein networkhttps://string-db.org/network/1715285.SOFFGTOCOR_0671SapB protein; Peptide transport system permease protein SapB.