Organism Overview: Baumannia cicadellinicola


 
mqo protein networkhttps://string-db.org/network/374463.BCI_0001Malate:quinone-oxidoreductase; Identified by match to protein family HMM PF06039; match to protein family HMM TIGR01320.
purL protein networkhttps://string-db.org/network/374463.BCI_0002Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ri [...]
tadA protein networkhttps://string-db.org/network/374463.BCI_0003Cytidine/deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase [...]
glyA protein networkhttps://string-db.org/network/374463.BCI_0004Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
suhB protein networkhttps://string-db.org/network/374463.BCI_0005Inositol-1-monophosphatase; Identified by similarity to SP:P22783; match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily.
iscS protein networkhttps://string-db.org/network/374463.BCI_0006Cysteine desulfurase; Identified by similarity to SP:P39171; match to protein family HMM PF00266; match to protein family HMM PF01212.
ndk protein networkhttps://string-db.org/network/374463.BCI_0007Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, [...]
ispG protein networkhttps://string-db.org/network/374463.BCI_00081-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG [...]
hisS protein networkhttps://string-db.org/network/374463.BCI_0009histidyl-tRNA synthetase; Identified by match to protein family HMM PF00587; match to protein family HMM PF03129; match to protein family HMM TIGR00442.
bamB protein networkhttps://string-db.org/network/374463.BCI_0010PQQ enzyme repeat domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
engA protein networkhttps://string-db.org/network/374463.BCI_0011GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) G [...]
pgi protein networkhttps://string-db.org/network/374463.BCI_0012Glucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342.
pckA protein networkhttps://string-db.org/network/374463.BCI_0013Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between th [...]
nudE protein networkhttps://string-db.org/network/374463.BCI_0014ADP compounds hydrolase NudE; Identified by similarity to SP:P45799; match to protein family HMM PF00293.
metK protein networkhttps://string-db.org/network/374463.BCI_0015S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet forma [...]
metR protein networkhttps://string-db.org/network/374463.BCI_0016Transcriptional regulator, MetR; Identified by similarity to SP:P19797; match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory fa [...]
metE protein networkhttps://string-db.org/network/374463.BCI_00175-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation [...]
BCI_0018 protein networkhttps://string-db.org/network/374463.BCI_0018RmuC domain protein; Identified by similarity to SP:P27850; match to protein family HMM PF02646.
metA protein networkhttps://string-db.org/network/374463.BCI_0019Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.
plsB protein networkhttps://string-db.org/network/374463.BCI_0020Glycerol-3-phosphate acyltransferase; Identified by similarity to SP:P00482; match to protein family HMM PF01553; Belongs to the GPAT/DAPAT family.
trpS protein networkhttps://string-db.org/network/374463.BCI_0021tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
rpe protein networkhttps://string-db.org/network/374463.BCI_0022Ribulose-phosphate 3-epimerase; Identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163; Belongs to the ribulose-phosphate 3-epimerase family.
aroB protein networkhttps://string-db.org/network/374463.BCI_00233-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquin [...]
aroK protein networkhttps://string-db.org/network/374463.BCI_0024Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
pssA protein networkhttps://string-db.org/network/374463.BCI_0025CDP-diacylglycerol--serine O-phosphatidyltransferase; Identified by similarity to SP:P23830; match to protein family HMM PF00614.
BCI_0026 protein networkhttps://string-db.org/network/374463.BCI_0026Identified by match to protein family HMM PF00597.
BCI_0027 protein networkhttps://string-db.org/network/374463.BCI_0027Identified by match to protein family HMM PF01722; Belongs to the BolA/IbaG family.
murA protein networkhttps://string-db.org/network/374463.BCI_0028UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
degQ protein networkhttps://string-db.org/network/374463.BCI_0029Serine protease; Identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037; Belongs to the peptidase S1C family.
BCI_0030 protein networkhttps://string-db.org/network/374463.BCI_0030Conserved hypothetical protein; Identified by match to protein family HMM PF06295.
rplM protein networkhttps://string-db.org/network/374463.BCI_0031Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of [...]
rpsI protein networkhttps://string-db.org/network/374463.BCI_0032Ribosomal protein S9; Identified by match to protein family HMM PF00380; Belongs to the universal ribosomal protein uS9 family.
purH protein networkhttps://string-db.org/network/374463.BCI_0035Bifunctional purine biosynthesis protein PurH; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355.
purD protein networkhttps://string-db.org/network/374463.BCI_0036Phosphoribosylamine--glycine ligase; Identified by match to protein family HMM PF01071; match to protein family HMM PF02842; match to protein family HMM PF02843; match to protein family HMM PF028 [...]
BCI_0037 protein networkhttps://string-db.org/network/374463.BCI_0037Heat shock protein; Identified by match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family.
BCI_0038 protein networkhttps://string-db.org/network/374463.BCI_0038Conserved hypothetical protein; Identified by match to protein family HMM PF01145.
nuc protein networkhttps://string-db.org/network/374463.BCI_0039Endonuclease; Identified by similarity to PIR:I79276.
hup protein networkhttps://string-db.org/network/374463.BCI_0040DNA-binding protein HU-alpha; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
thiC protein networkhttps://string-db.org/network/374463.BCI_0041Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methio [...]
thiE protein networkhttps://string-db.org/network/374463.BCI_0042Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamin [...]
thiF protein networkhttps://string-db.org/network/374463.BCI_00434-methyl-5-(beta-hydroxyethyl)thiazole monophosphate synthesis protein; Identified by match to protein family HMM PF00899; match to protein family HMM PF05237.
thiS protein networkhttps://string-db.org/network/374463.BCI_0044Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683.
thiG protein networkhttps://string-db.org/network/374463.BCI_0045Thiamine biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxy [...]
thiH protein networkhttps://string-db.org/network/374463.BCI_0046thiH protein; Identified by match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR02351.
mreD protein networkhttps://string-db.org/network/374463.BCI_0047Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.
mreC protein networkhttps://string-db.org/network/374463.BCI_0048Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
mreB protein networkhttps://string-db.org/network/374463.BCI_0049Rod shape-determining protein mreB; Identified by match to protein family HMM PF06723; match to protein family HMM TIGR00904.
aroQ protein networkhttps://string-db.org/network/374463.BCI_00503-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
accB protein networkhttps://string-db.org/network/374463.BCI_0051acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the car [...]
accC protein networkhttps://string-db.org/network/374463.BCI_0052acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein [...]
pitA protein networkhttps://string-db.org/network/374463.BCI_0055Low-affinity inorganic phosphate transporter; Identified by similarity to SP:P37308; match to protein family HMM PF01384.
ftsY protein networkhttps://string-db.org/network/374463.BCI_0056Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the [...]
ftsE protein networkhttps://string-db.org/network/374463.BCI_0057Cell division ATP-binding protein FtsE; Identified by similarity to SP:P10115; match to protein family HMM PF00005.
ftsX protein networkhttps://string-db.org/network/374463.BCI_0058Protein insertion permease FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
rpoH protein networkhttps://string-db.org/network/374463.BCI_0059Alternative sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved [...]
ubiB protein networkhttps://string-db.org/network/374463.BCI_0060Ferrisiderophore reductase; Identified by match to protein family HMM PF00175.
hemC protein networkhttps://string-db.org/network/374463.BCI_0061Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
hemD protein networkhttps://string-db.org/network/374463.BCI_0062uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
lnt protein networkhttps://string-db.org/network/374463.BCI_0063Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
ybeY protein networkhttps://string-db.org/network/374463.BCI_0064Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
miaB protein networkhttps://string-db.org/network/374463.BCI_0065tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) [...]
ligA protein networkhttps://string-db.org/network/374463.BCI_0066DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as t [...]
zipA protein networkhttps://string-db.org/network/374463.BCI_0067Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also req [...]
cysK protein networkhttps://string-db.org/network/374463.BCI_0068Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionin [...]
ptsH protein networkhttps://string-db.org/network/374463.BCI_0069Phosphocarrier protein HPr; Identified by similarity to SP:P07006; match to protein family HMM PF00381; match to protein family HMM TIGR01003.
ptsI protein networkhttps://string-db.org/network/374463.BCI_0070Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate ac [...]
purC protein networkhttps://string-db.org/network/374463.BCI_0071Phosphoribosylaminoimidazole-succinocarboxamide synthase; Identified by match to protein family HMM PF01259; match to protein family HMM TIGR00081; Belongs to the SAICAR synthetase family.
purM protein networkhttps://string-db.org/network/374463.BCI_0072Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR00878.
purN protein networkhttps://string-db.org/network/374463.BCI_0073Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylg [...]
ppk protein networkhttps://string-db.org/network/374463.BCI_0074Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
tktA protein networkhttps://string-db.org/network/374463.BCI_0075Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
talB protein networkhttps://string-db.org/network/374463.BCI_0076Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
cysT protein networkhttps://string-db.org/network/374463.BCI_0077Sulfate ABC transporter, permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport syste [...]
cysW protein networkhttps://string-db.org/network/374463.BCI_0078Sulfate ABC transporter, permease protein CysW; Identified by match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02140.
cysA protein networkhttps://string-db.org/network/374463.BCI_0079Sulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs [...]
rnfB protein networkhttps://string-db.org/network/374463.BCI_0080Ferredoxin II, 4Fe-4S bacterial type; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
tyrS protein networkhttps://string-db.org/network/374463.BCI_0081tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
pdxH protein networkhttps://string-db.org/network/374463.BCI_0082Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
slyA protein networkhttps://string-db.org/network/374463.BCI_0083Transcriptional regulator SlyA; Identified by similarity to SP:P55740; match to protein family HMM PF01047.
BCI_0084 protein networkhttps://string-db.org/network/374463.BCI_0084Hypothetical protein; Identified by Glimmer2; putative.
rnt protein networkhttps://string-db.org/network/374463.BCI_0085Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP [...]
BCI_0086 protein networkhttps://string-db.org/network/374463.BCI_0086Identified by match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily.
ribE protein networkhttps://string-db.org/network/374463.BCI_0087Riboflavin synthase, alpha subunit; Identified by match to protein family HMM PF00677; match to protein family HMM TIGR00187.
BCI_0089 protein networkhttps://string-db.org/network/374463.BCI_0089Major outer membrane lipoprotein; Identified by similarity to SP:P02937.
glnS protein networkhttps://string-db.org/network/374463.BCI_0094glutaminyl-tRNA synthetase; Identified by match to protein family HMM PF00749; match to protein family HMM PF03950; match to protein family HMM TIGR00440.
fldA protein networkhttps://string-db.org/network/374463.BCI_0095Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
BCI_0096 protein networkhttps://string-db.org/network/374463.BCI_0096Conserved hypothetical protein TIGR00486; Identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486.
sucC protein networkhttps://string-db.org/network/374463.BCI_0097succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus rep [...]
sucD protein networkhttps://string-db.org/network/374463.BCI_0098succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus re [...]
pal protein networkhttps://string-db.org/network/374463.BCI_0100Peptidoglycan-associated lipoprotein precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane [...]
BCI_0101 protein networkhttps://string-db.org/network/374463.BCI_0101Conserved hypothetical protein.
nadA protein networkhttps://string-db.org/network/374463.BCI_0102Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
tilS protein networkhttps://string-db.org/network/374463.BCI_0103tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is [...]
BCI_0104 protein networkhttps://string-db.org/network/374463.BCI_0104Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
BCI_0105 protein networkhttps://string-db.org/network/374463.BCI_0105Cation ABC transporter, permease protein; Identified by match to protein family HMM PF00950.
troB protein networkhttps://string-db.org/network/374463.BCI_0106Cation ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
ssb protein networkhttps://string-db.org/network/374463.BCI_0107Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action du [...]
BCI_0109 protein networkhttps://string-db.org/network/374463.BCI_0109Transcriptional regulator, MarR family; Identified by match to protein family HMM PF01047.
gmk protein networkhttps://string-db.org/network/374463.BCI_0110Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
rpoZ protein networkhttps://string-db.org/network/374463.BCI_0111DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and al [...]
recG protein networkhttps://string-db.org/network/374463.BCI_0112ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwindin [...]
engB protein networkhttps://string-db.org/network/374463.BCI_0113GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase fam [...]
polA protein networkhttps://string-db.org/network/374463.BCI_0114DNA polymerase I; Identified by similarity to SP:P00582; match to protein family HMM PF01367; match to protein family HMM PF02739.
dnaX protein networkhttps://string-db.org/network/374463.BCI_0115DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' [...]
BCI_0116 protein networkhttps://string-db.org/network/374463.BCI_0116Conserved hypothetical protein TIGR00103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
htpG protein networkhttps://string-db.org/network/374463.BCI_0117Heat shock protein HtpG; Molecular chaperone. Has ATPase activity.
adk protein networkhttps://string-db.org/network/374463.BCI_0118Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
purK protein networkhttps://string-db.org/network/374463.BCI_0119Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide [...]
purE protein networkhttps://string-db.org/network/374463.BCI_0120Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
cysS protein networkhttps://string-db.org/network/374463.BCI_0121cysteinyl-tRNA synthetase; Identified by match to protein family HMM PF01406; match to protein family HMM TIGR00435; Belongs to the class-I aminoacyl-tRNA synthetase family.
folD protein networkhttps://string-db.org/network/374463.BCI_01225,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate [...]
dapF protein networkhttps://string-db.org/network/374463.BCI_0125Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of t [...]
BCI_0126 protein networkhttps://string-db.org/network/374463.BCI_0126Haloacid dehalogenase-like hydrolase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.
uvrD protein networkhttps://string-db.org/network/374463.BCI_0127DNA helicase II; Identified by match to protein family HMM PF00580.
corA protein networkhttps://string-db.org/network/374463.BCI_0128Magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
BCI_0130 protein networkhttps://string-db.org/network/374463.BCI_0130Conserved hypothetical protein.
gyrB protein networkhttps://string-db.org/network/374463.BCI_0131DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in [...]
dnaN protein networkhttps://string-db.org/network/374463.BCI_0132DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadi [...]
rpmH protein networkhttps://string-db.org/network/374463.BCI_0133Ribosomal protein L34; Identified by match to protein family HMM PF00468; match to protein family HMM TIGR01030; Belongs to the bacterial ribosomal protein bL34 family.
rnpA protein networkhttps://string-db.org/network/374463.BCI_0134Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. [...]
BCI_0135 protein networkhttps://string-db.org/network/374463.BCI_0135Conserved hypothetical protein TIGR00278; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
yidC protein networkhttps://string-db.org/network/374463.BCI_0136Inner membrane protein oxaA; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane protein [...]
trmE protein networkhttps://string-db.org/network/374463.BCI_0137tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
glmS protein networkhttps://string-db.org/network/374463.BCI_0138Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [...]
glmU protein networkhttps://string-db.org/network/374463.BCI_0139UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyz [...]
atpC protein networkhttps://string-db.org/network/374463.BCI_0140ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
atpD protein networkhttps://string-db.org/network/374463.BCI_0141ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase [...]
atpG protein networkhttps://string-db.org/network/374463.BCI_0142ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the f [...]
atpA protein networkhttps://string-db.org/network/374463.BCI_0143ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains fa [...]
atpH protein networkhttps://string-db.org/network/374463.BCI_0144ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the e [...]
atpF protein networkhttps://string-db.org/network/374463.BCI_0145ATP synthase F0, B subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extra [...]
atpE protein networkhttps://string-db.org/network/374463.BCI_0146ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extra [...]
atpB protein networkhttps://string-db.org/network/374463.BCI_0147ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
gidA protein networkhttps://string-db.org/network/374463.BCI_0148Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s( [...]
gcvT protein networkhttps://string-db.org/network/374463.BCI_0149Glycine cleavage T-protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act [...]
recJ protein networkhttps://string-db.org/network/374463.BCI_0150single-stranded-DNA-specific exonuclease RecJ; Identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644.
lysS protein networkhttps://string-db.org/network/374463.BCI_0152lysyl-tRNA synthetase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00499; Belongs to the class-II aminoacyl-tRNA synthe [...]
murI protein networkhttps://string-db.org/network/374463.BCI_0153Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
glyS protein networkhttps://string-db.org/network/374463.BCI_0160glycyl-tRNA synthetase, beta subunit; Identified by match to protein family HMM PF02092; match to protein family HMM PF05746; match to protein family HMM TIGR00211.
glyQ protein networkhttps://string-db.org/network/374463.BCI_0161glycyl-tRNA synthetase, alpha subunit; Identified by match to protein family HMM PF02091; match to protein family HMM TIGR00388.
metF protein networkhttps://string-db.org/network/374463.BCI_01625,10-methylenetetrahydrofolate reductase; Identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676; Belongs to the methylenetetrahydrofolate reductase family.
metB protein networkhttps://string-db.org/network/374463.BCI_0163O-succinylhomoserine (thiol)-lyase; Identified by match to protein family HMM PF01053; match to protein family HMM TIGR02080.
rpmE protein networkhttps://string-db.org/network/374463.BCI_0165Ribosomal protein L31; Binds the 23S rRNA.
priA protein networkhttps://string-db.org/network/374463.BCI_0166Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its h [...]
hslV protein networkhttps://string-db.org/network/374463.BCI_0167ATP-dependent protease HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
hslU protein networkhttps://string-db.org/network/374463.BCI_0168Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by Hs [...]
tpiA protein networkhttps://string-db.org/network/374463.BCI_0169Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the [...]
BCI_0170 protein networkhttps://string-db.org/network/374463.BCI_0170Sulfate ABC transporter, sulfate-binding protein; Identified by similarity to SP:P06997; match to protein family HMM PF01547; match to protein family HMM TIGR00971.
pfkA protein networkhttps://string-db.org/network/374463.BCI_01716-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
cysE protein networkhttps://string-db.org/network/374463.BCI_0172Serine acetyltransferase; Identified by match to protein family HMM PF06426; match to protein family HMM TIGR01172.
gpsA protein networkhttps://string-db.org/network/374463.BCI_0173Glycerol-3-phosphate dehydrogenase; Identified by similarity to SP:P37606; match to protein family HMM PF01210; match to protein family HMM PF02558; match to protein family HMM PF07479; Belongs t [...]
BCI_0174 protein networkhttps://string-db.org/network/374463.BCI_0174Rhodanese domain protein; Identified by match to protein family HMM PF00581.
BCI_0175 protein networkhttps://string-db.org/network/374463.BCI_0175Peptidase, M23 family; Identified by match to protein family HMM PF01551.
coaD protein networkhttps://string-db.org/network/374463.BCI_0176Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial Co [...]
mutM protein networkhttps://string-db.org/network/374463.BCI_0177formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a [...]
rpmG protein networkhttps://string-db.org/network/374463.BCI_0178Ribosomal protein L33; Identified by match to protein family HMM PF00471; match to protein family HMM TIGR01023; Belongs to the bacterial ribosomal protein bL33 family.
rpmB protein networkhttps://string-db.org/network/374463.BCI_0179Ribosomal protein L28; Identified by match to protein family HMM PF00830; match to protein family HMM TIGR00009; Belongs to the bacterial ribosomal protein bL28 family.
BCI_0180 protein networkhttps://string-db.org/network/374463.BCI_0180Conserved hypothetical protein TIGR00255; Identified by match to protein family HMM PF03755; match to protein family HMM TIGR00255.
pyrE protein networkhttps://string-db.org/network/374463.BCI_0181Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
dut protein networkhttps://string-db.org/network/374463.BCI_0182Deoxyuridine 5''-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intrac [...]
dfp protein networkhttps://string-db.org/network/374463.BCI_0183Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantot [...]
rho protein networkhttps://string-db.org/network/374463.BCI_0188Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
trxA protein networkhttps://string-db.org/network/374463.BCI_0189Thioredoxin 1; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; Belongs to the thioredoxin family.
BCI_0190 protein networkhttps://string-db.org/network/374463.BCI_0190Conserved hypothetical protein; Identified by match to protein family HMM PF04219.
aroH protein networkhttps://string-db.org/network/374463.BCI_0191Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate [...]
bamD protein networkhttps://string-db.org/network/374463.BCI_0192Conserved hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
rluD protein networkhttps://string-db.org/network/374463.BCI_0193Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
clpB protein networkhttps://string-db.org/network/374463.BCI_0194ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE [...]
rplS protein networkhttps://string-db.org/network/374463.BCI_0195Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
trmD protein networkhttps://string-db.org/network/374463.BCI_0196tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rimM protein networkhttps://string-db.org/network/374463.BCI_019716S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19 [...]
rpsP protein networkhttps://string-db.org/network/374463.BCI_0198Ribosomal protein S16; Identified by match to protein family HMM PF00886; match to protein family HMM TIGR00002; Belongs to the bacterial ribosomal protein bS16 family.
ffh protein networkhttps://string-db.org/network/374463.BCI_0199Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nasce [...]
BCI_0200 protein networkhttps://string-db.org/network/374463.BCI_0200Hypothetical protein; Identified by Glimmer2; putative.
gshA protein networkhttps://string-db.org/network/374463.BCI_0201Glutamate--cysteine ligase; Identified by match to protein family HMM PF04262; match to protein family HMM TIGR01434; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
csrA protein networkhttps://string-db.org/network/374463.BCI_0204Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid g [...]
alaS protein networkhttps://string-db.org/network/374463.BCI_0205alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
recA protein networkhttps://string-db.org/network/374463.BCI_0206recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of hom [...]
BCI_0207 protein networkhttps://string-db.org/network/374463.BCI_0207Amino acid ABC transporter, periplasmic amino acid-binding protein; Identified by match to protein family HMM PF00497.
BCI_0208 protein networkhttps://string-db.org/network/374463.BCI_0208Amino acid ABC transporter, permease protein; Identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726.
mutS protein networkhttps://string-db.org/network/374463.BCI_0209DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase act [...]
ispF protein networkhttps://string-db.org/network/374463.BCI_02102C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid [...]
ispD protein networkhttps://string-db.org/network/374463.BCI_02112-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
cysC protein networkhttps://string-db.org/network/374463.BCI_0212Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
cysN protein networkhttps://string-db.org/network/374463.BCI_0213ATP-sulfurylase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. Cy [...]
cysD protein networkhttps://string-db.org/network/374463.BCI_0214Sulfate adenylyltransferase, small subunit; Identified by similarity to SP:P21156; match to protein family HMM PF01507; match to protein family HMM TIGR02039.
cysG protein networkhttps://string-db.org/network/374463.BCI_0215Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the [...]
cysH protein networkhttps://string-db.org/network/374463.BCI_0216Phosophoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
cysI protein networkhttps://string-db.org/network/374463.BCI_0217Sulfite reductase (NADPH) hemoprotein, beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities re [...]
cysJ protein networkhttps://string-db.org/network/374463.BCI_0218Sulfite reductase [NADPH] flavoprotein, alpha chain; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities re [...]
BCI_0219 protein networkhttps://string-db.org/network/374463.BCI_02196-pyruvoyl-tetrahydropterin synthase; Identified by match to protein family HMM PF01242.
queE protein networkhttps://string-db.org/network/374463.BCI_0220Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to th [...]
eno protein networkhttps://string-db.org/network/374463.BCI_0221Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
pyrG protein networkhttps://string-db.org/network/374463.BCI_0222CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the fo [...]
pfs protein networkhttps://string-db.org/network/374463.BCI_0224MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thio [...]
erpA protein networkhttps://string-db.org/network/374463.BCI_0225HesB family protein; Required for insertion of 4Fe-4S clusters for at least IspG.
dksA protein networkhttps://string-db.org/network/374463.BCI_0227DnaK suppressor protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of sever [...]
pcnB protein networkhttps://string-db.org/network/374463.BCI_0228poly(A) polymerase; Identified by match to protein family HMM PF01743; match to protein family HMM TIGR01942; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
folK protein networkhttps://string-db.org/network/374463.BCI_02297, 8-dihydro-6-hydroxymethylpterin-pyrophosphokina se; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498.
panB protein networkhttps://string-db.org/network/374463.BCI_02303-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to [...]
panC protein networkhttps://string-db.org/network/374463.BCI_0231Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase f [...]
leuS protein networkhttps://string-db.org/network/374463.BCI_0232leucyl-tRNA synthetase; Identified by match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family.
holA protein networkhttps://string-db.org/network/374463.BCI_0233DNA-directed DNA polymerase delta chain; Identified by match to protein family HMM PF06144; match to protein family HMM TIGR01128.
nadD protein networkhttps://string-db.org/network/374463.BCI_0234Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
mrdA protein networkhttps://string-db.org/network/374463.BCI_0235Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
mrdB protein networkhttps://string-db.org/network/374463.BCI_0236Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
lipB protein networkhttps://string-db.org/network/374463.BCI_0237Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can al [...]
lipA protein networkhttps://string-db.org/network/374463.BCI_0238Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes [...]
mdtH protein networkhttps://string-db.org/network/374463.BCI_0239Transporter, major facilitator family; Identified by match to protein family HMM PF07690.
pgsA protein networkhttps://string-db.org/network/374463.BCI_0240CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; Belongs to the CDP-alcohol phosphatid [...]
pgl protein networkhttps://string-db.org/network/374463.BCI_02446-phosphogluconolactonase.
bioA protein networkhttps://string-db.org/network/374463.BCI_0245Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8 [...]
bioB protein networkhttps://string-db.org/network/374463.BCI_0246Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily [...]
bioF protein networkhttps://string-db.org/network/374463.BCI_02478-amino-7-oxononanoate synthase; Identified by similarity to SP:P12998; match to protein family HMM PF00155.
bioC protein networkhttps://string-db.org/network/374463.BCI_0248Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synth [...]
bioD protein networkhttps://string-db.org/network/374463.BCI_0249Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an urei [...]
BCI_0250 protein networkhttps://string-db.org/network/374463.BCI_0250ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
gpmA protein networkhttps://string-db.org/network/374463.BCI_0251Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
serC protein networkhttps://string-db.org/network/374463.BCI_0252Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belon [...]
aroA protein networkhttps://string-db.org/network/374463.BCI_02533-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl [...]
cmk protein networkhttps://string-db.org/network/374463.BCI_0254Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017.
rpsA protein networkhttps://string-db.org/network/374463.BCI_0255Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
BCI_0256 protein networkhttps://string-db.org/network/374463.BCI_0256Conserved hypothetical protein; Identified by match to protein family HMM PF03966; Belongs to the UPF0434 family.
dsbA protein networkhttps://string-db.org/network/374463.BCI_0257Thiol:disulfide interchange protein DsbA; Identified by similarity to SP:P24991; match to protein family HMM PF01323.
pyrB protein networkhttps://string-db.org/network/374463.BCI_0258Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine c [...]
pyrI protein networkhttps://string-db.org/network/374463.BCI_0259Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
BCI_0260 protein networkhttps://string-db.org/network/374463.BCI_0260Putative endoribonuclease L-PSP; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004.
cspE protein networkhttps://string-db.org/network/374463.BCI_0261Cold shock-like protein CspE; Identified by similarity to SP:P36997; match to protein family HMM PF00313.
exsB protein networkhttps://string-db.org/network/374463.BCI_0262exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
lon protein networkhttps://string-db.org/network/374463.BCI_0263ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for [...]
clpX protein networkhttps://string-db.org/network/374463.BCI_0264ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in t [...]
clpP protein networkhttps://string-db.org/network/374463.BCI_0265ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the d [...]
tig protein networkhttps://string-db.org/network/374463.BCI_0266Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs t [...]
cyoA protein networkhttps://string-db.org/network/374463.BCI_0267Ubiquinol oxidase, subunit II; Identified by match to protein family HMM PF00116; match to protein family HMM PF06481; match to protein family HMM TIGR01433.
cyoB protein networkhttps://string-db.org/network/374463.BCI_0268Ubiquinol oxidase, polypeptide I; Identified by similarity to SP:P18401; match to protein family HMM PF00115; Belongs to the heme-copper respiratory oxidase family.
cyoC protein networkhttps://string-db.org/network/374463.BCI_0269Cytochrome o ubiquinol oxidase, subunit III; Identified by similarity to SP:P18402.
cyoE protein networkhttps://string-db.org/network/374463.BCI_0270Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
BCI_0271 protein networkhttps://string-db.org/network/374463.BCI_0271Transporter, major facilitator family; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690.
panE protein networkhttps://string-db.org/network/374463.BCI_02722-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
thiI protein networkhttps://string-db.org/network/374463.BCI_0273Thiamine biosynthesis protein ThiI; Identified by similarity to SP:P77718.
ispA protein networkhttps://string-db.org/network/374463.BCI_0274Geranyltranstransferase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.
dxs protein networkhttps://string-db.org/network/374463.BCI_02751-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (D [...]
argS protein networkhttps://string-db.org/network/374463.BCI_0276arginyl-tRNA synthetase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456.
mviN protein networkhttps://string-db.org/network/374463.BCI_0277Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
acpS protein networkhttps://string-db.org/network/374463.BCI_0278Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
pdxJ protein networkhttps://string-db.org/network/374463.BCI_0279Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phos [...]
era protein networkhttps://string-db.org/network/374463.BCI_0280GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly als [...]
rnc protein networkhttps://string-db.org/network/374463.BCI_0281Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some m [...]
lepB protein networkhttps://string-db.org/network/374463.BCI_0282Signal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family.
lepA protein networkhttps://string-db.org/network/374463.BCI_0283GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codo [...]
valS protein networkhttps://string-db.org/network/374463.BCI_0285valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
holC protein networkhttps://string-db.org/network/374463.BCI_0286DNA polymerase III, chi subunit; Identified by match to protein family HMM PF04364.
pepA protein networkhttps://string-db.org/network/374463.BCI_0287Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
nadE protein networkhttps://string-db.org/network/374463.BCI_0288NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
hemK protein networkhttps://string-db.org/network/374463.BCI_0289Protein methyltranferase HemK; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the [...]
prfA protein networkhttps://string-db.org/network/374463.BCI_0290Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
lolB protein networkhttps://string-db.org/network/374463.BCI_0291Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
ispE protein networkhttps://string-db.org/network/374463.BCI_02924-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
prsA protein networkhttps://string-db.org/network/374463.BCI_0293Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to [...]
pth protein networkhttps://string-db.org/network/374463.BCI_0294peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
ychF protein networkhttps://string-db.org/network/374463.BCI_0295GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
fabI protein networkhttps://string-db.org/network/374463.BCI_0296Enoyl-[acyl-carrier-protein] reductase; Identified by similarity to SP:P29132.
rnb protein networkhttps://string-db.org/network/374463.BCI_0297Exoribonuclease II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
pyrF protein networkhttps://string-db.org/network/374463.BCI_0298Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamil [...]
lapA protein networkhttps://string-db.org/network/374463.BCI_0299Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
ribA protein networkhttps://string-db.org/network/374463.BCI_0300GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II famil [...]
cysB protein networkhttps://string-db.org/network/374463.BCI_0301Cys regulon transcriptional activator CysB; Identified by similarity to SP:P06613; match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional re [...]
topA protein networkhttps://string-db.org/network/374463.BCI_0302DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of [...]
BCI_0303 protein networkhttps://string-db.org/network/374463.BCI_0303Conserved hypothetical protein; Identified by match to protein family HMM PF06790.
BCI_0304 protein networkhttps://string-db.org/network/374463.BCI_0304Conserved hypothetical protein; Identified by match to protein family HMM PF03795.
cls protein networkhttps://string-db.org/network/374463.BCI_0305Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belong [...]
hns protein networkhttps://string-db.org/network/374463.BCI_0306DNA-binding protein H-NS; Identified by similarity to SP:P08936; match to protein family HMM PF00816; Belongs to the histone-like protein H-NS family.
htpX protein networkhttps://string-db.org/network/374463.BCI_0307Heat shock protein, integral membrane protein; Identified by match to protein family HMM PF01435; match to protein family HMM PF06509; Belongs to the peptidase M48B family.
ftn protein networkhttps://string-db.org/network/374463.BCI_0308Ferritin; Iron-storage protein.
zwf protein networkhttps://string-db.org/network/374463.BCI_0309Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
pykA protein networkhttps://string-db.org/network/374463.BCI_0310Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
mntH protein networkhttps://string-db.org/network/374463.BCI_0311Mn2+/Fe2+ transporter, NRAMP family; H(+)-stimulated, divalent metal cation uptake system.
ruvB protein networkhttps://string-db.org/network/374463.BCI_0312Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand [...]
ruvA protein networkhttps://string-db.org/network/374463.BCI_0313Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand [...]
ruvC protein networkhttps://string-db.org/network/374463.BCI_0314Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to st [...]
aspS protein networkhttps://string-db.org/network/374463.BCI_0315aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor [...]
BCI_0316 protein networkhttps://string-db.org/network/374463.BCI_0316PHP family protein; Identified by match to protein family HMM PF02811.
serS protein networkhttps://string-db.org/network/374463.BCI_0318seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further [...]
lolA protein networkhttps://string-db.org/network/374463.BCI_0319Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the re [...]
ftsK protein networkhttps://string-db.org/network/374463.BCI_0320DNA translocase ftsK; Identified by match to protein family HMM PF01580; Belongs to the FtsK/SpoIIIE/SftA family.
trxB protein networkhttps://string-db.org/network/374463.BCI_0321Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292.
infA protein networkhttps://string-db.org/network/374463.BCI_0322Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
artP protein networkhttps://string-db.org/network/374463.BCI_0323Arginine ABC transporter, ATP-binding protein; Identified by similarity to SP:P30858; match to protein family HMM PF00005.
artI protein networkhttps://string-db.org/network/374463.BCI_0324Arginine ABC-transporter, arginine binding protein; Identified by match to protein family HMM PF00497; Belongs to the bacterial solute-binding protein 3 family.
artQ protein networkhttps://string-db.org/network/374463.BCI_0325Arginine ABC transporter, permease protein; Identified by match to protein family HMM PF00528.
artM protein networkhttps://string-db.org/network/374463.BCI_0326Arginine ABC transporter, permease protein; Identified by similarity to SP:P30862; match to protein family HMM PF00528; match to protein family HMM TIGR01726.
rpsJ protein networkhttps://string-db.org/network/374463.BCI_0327Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
rplC protein networkhttps://string-db.org/network/374463.BCI_0328Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rplD protein networkhttps://string-db.org/network/374463.BCI_0329Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes mul [...]
rplW protein networkhttps://string-db.org/network/374463.BCI_0330Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking [...]
rplB protein networkhttps://string-db.org/network/374463.BCI_0331Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has [...]
rpsS protein networkhttps://string-db.org/network/374463.BCI_0332Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplV protein networkhttps://string-db.org/network/374463.BCI_0333Ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S as [...]
rpsC protein networkhttps://string-db.org/network/374463.BCI_0334Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplP protein networkhttps://string-db.org/network/374463.BCI_0335Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpmC protein networkhttps://string-db.org/network/374463.BCI_0336Ribosomal protein L29; Identified by match to protein family HMM PF00831; match to protein family HMM TIGR00012; Belongs to the universal ribosomal protein uL29 family.
rpsQ protein networkhttps://string-db.org/network/374463.BCI_0337Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rplN protein networkhttps://string-db.org/network/374463.BCI_033850S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rplX protein networkhttps://string-db.org/network/374463.BCI_0339Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rplE protein networkhttps://string-db.org/network/374463.BCI_034050S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [...]
rpsN protein networkhttps://string-db.org/network/374463.BCI_0341Ribosomal protein S14p; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the unive [...]
rpsH protein networkhttps://string-db.org/network/374463.BCI_0342Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the [...]
rp1F protein networkhttps://string-db.org/network/374463.BCI_034350S ribosomal subunit protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and ne [...]
rplR protein networkhttps://string-db.org/network/374463.BCI_0344Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
rpsE protein networkhttps://string-db.org/network/374463.BCI_0345Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
rpmD protein networkhttps://string-db.org/network/374463.BCI_0346Ribosomal protein L30; Identified by match to protein family HMM PF00327; match to protein family HMM TIGR01308.
rplO protein networkhttps://string-db.org/network/374463.BCI_0347Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
secY protein networkhttps://string-db.org/network/374463.BCI_0348Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at [...]
rpmJ protein networkhttps://string-db.org/network/374463.BCI_0349Ribosomal protein L36; Identified by match to protein family HMM PF00444; match to protein family HMM TIGR01022; Belongs to the bacterial ribosomal protein bL36 family.
rpsM protein networkhttps://string-db.org/network/374463.BCI_0350Ribosomal protein S13p; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of [...]
rpsK protein networkhttps://string-db.org/network/374463.BCI_0351Ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs t [...]
rpsD protein networkhttps://string-db.org/network/374463.BCI_0352Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpoA protein networkhttps://string-db.org/network/374463.BCI_0353DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplQ protein networkhttps://string-db.org/network/374463.BCI_0354Ribosomal protein L17; Identified by match to protein family HMM PF01196; match to protein family HMM TIGR00059.
coaA protein networkhttps://string-db.org/network/374463.BCI_0359Pantothenate kinase; Identified by match to protein family HMM PF00485; match to protein family HMM TIGR00554.
prmB protein networkhttps://string-db.org/network/374463.BCI_0360protein-(glutamine-N5) methyltransferase; Identified by match to protein family HMM PF05175; match to protein family HMM TIGR00536; Belongs to the protein N5-glutamine methyltransferase family.
aroC protein networkhttps://string-db.org/network/374463.BCI_0361Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
fabB protein networkhttps://string-db.org/network/374463.BCI_03623-oxoacyl-[acyl-carrier-protein] synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF02801; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synt [...]
pdxB protein networkhttps://string-db.org/network/374463.BCI_0363Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
truA protein networkhttps://string-db.org/network/374463.BCI_0364tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
accD protein networkhttps://string-db.org/network/374463.BCI_0365acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carr [...]
folC protein networkhttps://string-db.org/network/374463.BCI_0366Dihydrofolate:folylpolyglutamate synthetase; Identified by match to protein family HMM PF02875; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family.
cvpA protein networkhttps://string-db.org/network/374463.BCI_0367Identified by match to protein family HMM PF02674.
purF protein networkhttps://string-db.org/network/374463.BCI_0368Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine p [...]
nuoN protein networkhttps://string-db.org/network/374463.BCI_0369Proton-translocating NADH-quinone oxidoreductase, chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron [...]
nuoM protein networkhttps://string-db.org/network/374463.BCI_0370Proton-translocating NADH-quinone oxidoreductase, chain M; Identified by similarity to SP:P31978; match to protein family HMM PF00361; match to protein family HMM TIGR01972.
nuoL protein networkhttps://string-db.org/network/374463.BCI_0371Proton-translocating NADH-quinone oxidoreductase, chain L; Identified by match to protein family HMM PF00361; match to protein family HMM PF00662; match to protein family HMM TIGR01974.
nuoK protein networkhttps://string-db.org/network/374463.BCI_0372NADH-quinone oxidoreductase, chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enz [...]
nuoJ protein networkhttps://string-db.org/network/374463.BCI_0373NADH-quinone oxidoreductase, chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton transl [...]
nuoI protein networkhttps://string-db.org/network/374463.BCI_0374NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enz [...]
nuoH protein networkhttps://string-db.org/network/374463.BCI_0375NADH-quinone oxidoreductase, chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enz [...]
nuoG protein networkhttps://string-db.org/network/374463.BCI_0376NADH-quinone oxidoreductase, chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton transl [...]
nuoF protein networkhttps://string-db.org/network/374463.BCI_0377NADH-quinone oxidoreductase, F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit f [...]
nuoE protein networkhttps://string-db.org/network/374463.BCI_0378NADH-quinone oxidoreductase, E subunit; Identified by similarity to SP:P33601; match to protein family HMM PF01257; match to protein family HMM TIGR01958.
nuoCD protein networkhttps://string-db.org/network/374463.BCI_0379NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoB protein networkhttps://string-db.org/network/374463.BCI_0380NADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the e [...]
nuoA protein networkhttps://string-db.org/network/374463.BCI_0381NADH-quinone oxidoreductase, subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the e [...]
ackA protein networkhttps://string-db.org/network/374463.BCI_0382Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
pta protein networkhttps://string-db.org/network/374463.BCI_0383Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
BCI_0384 protein networkhttps://string-db.org/network/374463.BCI_0384Iron-sulfur cluster binding protein; Identified by match to protein family HMM PF00111.
nrdB protein networkhttps://string-db.org/network/374463.BCI_0385Ribonucleoside-diphosphate reductase, beta subunit; Identified by similarity to SP:P00453; match to protein family HMM PF00268.
BCI_0386 protein networkhttps://string-db.org/network/374463.BCI_0386Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [...]
gyrA protein networkhttps://string-db.org/network/374463.BCI_0387DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in [...]
ddlA protein networkhttps://string-db.org/network/374463.BCI_0388D-ala D-ala ligase; Cell wall formation.
rplY protein networkhttps://string-db.org/network/374463.BCI_039050S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 fa [...]
BCI_0391 protein networkhttps://string-db.org/network/374463.BCI_0391Identified by match to protein family HMM PF00877.
nfo protein networkhttps://string-db.org/network/374463.BCI_0392Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-p [...]
lysP protein networkhttps://string-db.org/network/374463.BCI_0393Lysine-specific permease; Identified by match to protein family HMM PF00324.
folE protein networkhttps://string-db.org/network/374463.BCI_0394GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.
dcd protein networkhttps://string-db.org/network/374463.BCI_03952-deoxycytidine 5-triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.
metG protein networkhttps://string-db.org/network/374463.BCI_0396methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
gnd protein networkhttps://string-db.org/network/374463.BCI_03976-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
hisI protein networkhttps://string-db.org/network/374463.BCI_0398phosphoribosyl-AMP cyclohydrolase; Identified by match to protein family HMM PF01502; match to protein family HMM PF01503; In the N-terminal section; belongs to the PRA-CH family.
hisF protein networkhttps://string-db.org/network/374463.BCI_0399Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that p [...]
hisA protein networkhttps://string-db.org/network/374463.BCI_0400Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Identified by match to protein family HMM PF00977; match to protein family HMM TIGR00007.
hisH protein networkhttps://string-db.org/network/374463.BCI_0401Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydroly [...]
hisB protein networkhttps://string-db.org/network/374463.BCI_0402Histidinol-phosphatase/imidazoleglycerol- phosphate dehydratase; Identified by match to protein family HMM PF00475; match to protein family HMM TIGR01261; match to protein family HMM TIGR01656; m [...]
hisC protein networkhttps://string-db.org/network/374463.BCI_0403Histidinol-phosphate aminotransferase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransfe [...]
hisD protein networkhttps://string-db.org/network/374463.BCI_0404Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
hisG protein networkhttps://string-db.org/network/374463.BCI_0405ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate [...]
BCI_0406 protein networkhttps://string-db.org/network/374463.BCI_0406Metallo-beta-lactamase superfamily protein; Identified by match to protein family HMM PF00753.
aspC protein networkhttps://string-db.org/network/374463.BCI_0407Aspartate aminotransferase; Identified by match to protein family HMM PF00155.
asnS protein networkhttps://string-db.org/network/374463.BCI_0408asparaginyl-tRNA synthetase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00457.
pyrD protein networkhttps://string-db.org/network/374463.BCI_0409Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
fabA protein networkhttps://string-db.org/network/374463.BCI_0410Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-de [...]
BCI_0411 protein networkhttps://string-db.org/network/374463.BCI_0411Conserved hypothetical protein; Identified by similarity to GB:CAG74654.1.
hspQ protein networkhttps://string-db.org/network/374463.BCI_0412Conserved hypothetical protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family.
dsvC protein networkhttps://string-db.org/network/374463.BCI_0413Dissimilatory sulfite reductase, gamma subunit; Identified by match to protein family HMM PF04358.
fmt protein networkhttps://string-db.org/network/374463.BCI_0415methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
def protein networkhttps://string-db.org/network/374463.BCI_0416Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...]
tsaC protein networkhttps://string-db.org/network/374463.BCI_0417Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conve [...]
aroE protein networkhttps://string-db.org/network/374463.BCI_0418Dehydroshikimate reductase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydrosh [...]
BCI_0419 protein networkhttps://string-db.org/network/374463.BCI_0419Pyruvate-flavodoxin oxidoreductase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02 [...]
fumC protein networkhttps://string-db.org/network/374463.BCI_0420Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamil [...]
trmU protein networkhttps://string-db.org/network/374463.BCI_0422tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
purB protein networkhttps://string-db.org/network/374463.BCI_0423Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
lolE protein networkhttps://string-db.org/network/374463.BCI_0424Lipoprotein releasing system, transmembrane protein LolE; Identified by similarity to SP:P75958; match to protein family HMM PF02687; match to protein family HMM TIGR02212.
lolD protein networkhttps://string-db.org/network/374463.BCI_0425Lipoprotein releasing system, ATP-binding protein; Identified by similarity to SP:P75957; match to protein family HMM PF00005; match to protein family HMM TIGR02211; Belongs to the ABC transporte [...]
lolC protein networkhttps://string-db.org/network/374463.BCI_0426Lipoprotein releasing system, transmembrane protein LolC; Identified by similarity to SP:P75956; match to protein family HMM PF02687; match to protein family HMM TIGR02212.
BCI_0427 protein networkhttps://string-db.org/network/374463.BCI_0427Conserved hypothetical protein; Identified by similarity to GB:CAH21689.1.
BCI_0428 protein networkhttps://string-db.org/network/374463.BCI_0428Hit family protein; Identified by match to protein family HMM PF01230.
BCI_0429 protein networkhttps://string-db.org/network/374463.BCI_0429Deoxyribonuclease; Identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010.
holB protein networkhttps://string-db.org/network/374463.BCI_0430DNA polymerase III, delta' subunit; Identified by similarity to SP:P28631.
tmk protein networkhttps://string-db.org/network/374463.BCI_0431Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
pabC protein networkhttps://string-db.org/network/374463.BCI_04324-amino-4-deoxychorismate lyase; Identified by match to protein family HMM PF01063.
acpP protein networkhttps://string-db.org/network/374463.BCI_0433Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
fabG protein networkhttps://string-db.org/network/374463.BCI_04343-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cy [...]
fabD protein networkhttps://string-db.org/network/374463.BCI_0435Malonyl CoA-acyl carrier protein transacylase; Identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128.
fabH protein networkhttps://string-db.org/network/374463.BCI_04363-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first [...]
BCI_0437 protein networkhttps://string-db.org/network/374463.BCI_0437Hypothetical protein; Identified by Glimmer2; putative.
rpmF protein networkhttps://string-db.org/network/374463.BCI_0438Ribosomal protein L32; Identified by match to protein family HMM PF01783; match to protein family HMM TIGR01031; Belongs to the bacterial ribosomal protein bL32 family.
rluC protein networkhttps://string-db.org/network/374463.BCI_0439Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
rne protein networkhttps://string-db.org/network/374463.BCI_0440Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation [...]
pyrC protein networkhttps://string-db.org/network/374463.BCI_0441Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
sppA protein networkhttps://string-db.org/network/374463.BCI_0442Signal peptide peptidase SppA, 67K type; Identified by match to protein family HMM PF01343; match to protein family HMM TIGR00705; match to protein family HMM TIGR00706.
gapA protein networkhttps://string-db.org/network/374463.BCI_0443Glyceraldehyde-3-phosphate dehydrogenase, type I; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the gly [...]
minC protein networkhttps://string-db.org/network/374463.BCI_0444Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments tha [...]
minD protein networkhttps://string-db.org/network/374463.BCI_0445Septum site-determining protein MinD; Identified by match to protein family HMM PF01656; match to protein family HMM TIGR01968.
minE protein networkhttps://string-db.org/network/374463.BCI_0446Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensu [...]
BCI_0447 protein networkhttps://string-db.org/network/374463.BCI_0447Identified by match to protein family HMM PF00814.
BCI_0448 protein networkhttps://string-db.org/network/374463.BCI_0448Conserved hypothetical protein; Identified by match to protein family HMM PF03734.
BCI_0449 protein networkhttps://string-db.org/network/374463.BCI_0449PTS system, mannose/fructose/sorbose family, IID component; Identified by similarity to SP:P08188; match to protein family HMM PF03613; match to protein family HMM TIGR00828.
BCI_0450 protein networkhttps://string-db.org/network/374463.BCI_0450PTS system, mannose/fructose/sorbose family, IIC component; Identified by match to protein family HMM PF03609; match to protein family HMM TIGR00822.
BCI_0451 protein networkhttps://string-db.org/network/374463.BCI_0451PTS system, mannose/fructose/sorbose family, IIAB component; Identified by match to protein family HMM PF03610; match to protein family HMM PF03830; match to protein family HMM TIGR00824; match t [...]
BCI_0452 protein networkhttps://string-db.org/network/374463.BCI_0452Membrane protein, TerC family; Identified by match to protein family HMM PF00571; match to protein family HMM PF03741.
pabB protein networkhttps://string-db.org/network/374463.BCI_0453Para-aminobenzoate synthase, component I; Identified by match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553.
BCI_0454 protein networkhttps://string-db.org/network/374463.BCI_0454Rhodanese-like domain protein; Identified by similarity to GB:CAG74686.1; match to protein family HMM PF00581; Belongs to the UPF0176 family.
gltX protein networkhttps://string-db.org/network/374463.BCI_0456glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end [...]
BCI_0459 protein networkhttps://string-db.org/network/374463.BCI_0459Drug resistance transporter, EmrB/QacA subfamily; Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; Belongs to the major facilitator superfamily.
emrA protein networkhttps://string-db.org/network/374463.BCI_0460Multidrug resistance protein; Identified by match to protein family HMM PF00529.
sufE protein networkhttps://string-db.org/network/374463.BCI_0461SufE protein; Identified by match to protein family HMM PF02657.
sufS protein networkhttps://string-db.org/network/374463.BCI_0462Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
sufD protein networkhttps://string-db.org/network/374463.BCI_0463FeS assembly protein SufD; Identified by match to protein family HMM PF01458; match to protein family HMM TIGR01981.
sufC protein networkhttps://string-db.org/network/374463.BCI_0464FeS assembly ATPase SufC; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978.
sufB protein networkhttps://string-db.org/network/374463.BCI_0465FeS assembly protein SufB; Identified by match to protein family HMM PF01458; match to protein family HMM TIGR01980.
sufA protein networkhttps://string-db.org/network/374463.BCI_0466Iron-sulfur cluster assembly accessory protein; Identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049; Belongs to the HesB/IscA family.
pheT protein networkhttps://string-db.org/network/374463.BCI_0467phenylalanyl-tRNA synthetase, beta subunit; Identified by match to protein family HMM PF01588; match to protein family HMM PF03147; match to protein family HMM PF03483; match to protein family HM [...]
pheS protein networkhttps://string-db.org/network/374463.BCI_0468phenylalanyl-tRNA synthetase, alpha subunit; Identified by match to protein family HMM PF01409; match to protein family HMM PF02912; match to protein family HMM TIGR00468; Belongs to the class-II [...]
rplT protein networkhttps://string-db.org/network/374463.BCI_0469Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing function [...]
rpmI protein networkhttps://string-db.org/network/374463.BCI_0470Ribosomal protein L35; Identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001; Belongs to the bacterial ribosomal protein bL35 family.
infC protein networkhttps://string-db.org/network/374463.BCI_0471Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enha [...]
thrS protein networkhttps://string-db.org/network/374463.BCI_0472threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor en [...]
dnaQ protein networkhttps://string-db.org/network/374463.BCI_0473DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing func [...]
rnhA protein networkhttps://string-db.org/network/374463.BCI_0474RNase H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
gloB protein networkhttps://string-db.org/network/374463.BCI_0475Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
BCI_0476 protein networkhttps://string-db.org/network/374463.BCI_0476Identified by match to protein family HMM PF03372.
mltC protein networkhttps://string-db.org/network/374463.BCI_0477Membrane-bound lytic murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.
BCI_0478 protein networkhttps://string-db.org/network/374463.BCI_0478Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic en [...]
BCI_0479 protein networkhttps://string-db.org/network/374463.BCI_0479Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalentl [...]
BCI_0481 protein networkhttps://string-db.org/network/374463.BCI_0481Conserved hypothetical protein; Identified by match to protein family HMM PF02622; Belongs to the UPF0301 (AlgH) family.
gshB protein networkhttps://string-db.org/network/374463.BCI_0482Glutathione synthetase; Identified by match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase fami [...]
sodA protein networkhttps://string-db.org/network/374463.BCI_0483Manganese superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family [...]
nfuA protein networkhttps://string-db.org/network/374463.BCI_0484yhgI protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also a [...]
bioH protein networkhttps://string-db.org/network/374463.BCI_0485bioH protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthet [...]
fur protein networkhttps://string-db.org/network/374463.BCI_0488Zinc uptake regulation protein; Identified by match to protein family HMM PF01475; Belongs to the Fur family.
dsrE protein networkhttps://string-db.org/network/374463.BCI_0489Intracellular sulfur reduction protein DsrE; Identified by match to protein family HMM PF02635.
dsrF protein networkhttps://string-db.org/network/374463.BCI_0490Intracellular reduction protein DsrF; Identified by match to protein family HMM PF02635; Belongs to the DsrF/TusC family.
dsrH protein networkhttps://string-db.org/network/374463.BCI_0491Intracellular sulfur oxidation protein DsrH; Identified by match to protein family HMM PF04077.
rpsL protein networkhttps://string-db.org/network/374463.BCI_0492Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
rpsG protein networkhttps://string-db.org/network/374463.BCI_0493Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interfac [...]
fusA protein networkhttps://string-db.org/network/374463.BCI_0494Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) [...]
tuf protein networkhttps://string-db.org/network/374463.BCI_0495Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
secE protein networkhttps://string-db.org/network/374463.BCI_0496Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; B [...]
nusG protein networkhttps://string-db.org/network/374463.BCI_0497Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination.
rplK protein networkhttps://string-db.org/network/374463.BCI_0498Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
rplA protein networkhttps://string-db.org/network/374463.BCI_049950S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplJ protein networkhttps://string-db.org/network/374463.BCI_050050S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal prot [...]
rplL protein networkhttps://string-db.org/network/374463.BCI_0501Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacter [...]
rpoB protein networkhttps://string-db.org/network/374463.BCI_0502DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoC protein networkhttps://string-db.org/network/374463.BCI_0503DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
murB protein networkhttps://string-db.org/network/374463.BCI_0504UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
birA protein networkhttps://string-db.org/network/374463.BCI_0505biotin-[acetyl-CoA-carboxylase] ligase; Identified by similarity to SP:P06709; match to protein family HMM PF03099; match to protein family HMM TIGR00121.
lpdA protein networkhttps://string-db.org/network/374463.BCI_0510Pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM P [...]
aceF protein networkhttps://string-db.org/network/374463.BCI_0511Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF02817.
aceE protein networkhttps://string-db.org/network/374463.BCI_0512Pyruvate dehydrogenase, E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
nadC protein networkhttps://string-db.org/network/374463.BCI_0513Nicotinate-nucleotide pyrophosphorylase; Identified by match to protein family HMM PF01729; match to protein family HMM PF02749; match to protein family HMM TIGR00078; Belongs to the NadC/ModD fa [...]
coaE protein networkhttps://string-db.org/network/374463.BCI_0514dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
BCI_0516 protein networkhttps://string-db.org/network/374463.BCI_0516Conserved hypothetical protein.
ftsZ protein networkhttps://string-db.org/network/374463.BCI_0517Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the tim [...]
murC protein networkhttps://string-db.org/network/374463.BCI_0518UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
murG protein networkhttps://string-db.org/network/374463.BCI_0519Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid interme [...]
murD protein networkhttps://string-db.org/network/374463.BCI_0520UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF [...]
mraY protein networkhttps://string-db.org/network/374463.BCI_0521phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan.
murF protein networkhttps://string-db.org/network/374463.BCI_0522UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of mure [...]
murE protein networkhttps://string-db.org/network/374463.BCI_0523UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG [...]
mraW protein networkhttps://string-db.org/network/374463.BCI_0524S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
queF protein networkhttps://string-db.org/network/374463.BCI_0525GTP cyclohydrolase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
map protein networkhttps://string-db.org/network/374463.BCI_0526Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and [...]
rpsB protein networkhttps://string-db.org/network/374463.BCI_0527Ribosomal protein S2; Identified by match to protein family HMM PF00318; match to protein family HMM TIGR01011; Belongs to the universal ribosomal protein uS2 family.
tsf protein networkhttps://string-db.org/network/374463.BCI_0528Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis [...]
pyrH protein networkhttps://string-db.org/network/374463.BCI_0529Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
frr protein networkhttps://string-db.org/network/374463.BCI_0530Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
dxr protein networkhttps://string-db.org/network/374463.BCI_05311-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Be [...]
uppS protein networkhttps://string-db.org/network/374463.BCI_0532Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,3 [...]
cdsA protein networkhttps://string-db.org/network/374463.BCI_0533Phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF01148; Belongs to the CDS family.
BCI_0534 protein networkhttps://string-db.org/network/374463.BCI_0534Protease EcfE; Identified by similarity to SP:P37764; match to protein family HMM PF00595; match to protein family HMM PF02163; match to protein family HMM TIGR00054.
bamA protein networkhttps://string-db.org/network/374463.BCI_0535Outer membrane protein, OMP85 family; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
ompH protein networkhttps://string-db.org/network/374463.BCI_0536Outer membrane protein OmpH; Identified by similarity to SP:P31519; match to protein family HMM PF03938; Belongs to the skp family.
fabZ protein networkhttps://string-db.org/network/374463.BCI_0537Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated [...]
dnaE protein networkhttps://string-db.org/network/374463.BCI_0538DNA polymerase III, alpha subunit; Identified by similarity to SP:P10443; match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to p [...]
accA protein networkhttps://string-db.org/network/374463.BCI_0539acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its c [...]
metC protein networkhttps://string-db.org/network/374463.BCI_0540Cystathionine beta-lyase; Identified by match to protein family HMM PF01053; match to protein family HMM TIGR01324.
mutH protein networkhttps://string-db.org/network/374463.BCI_0541DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.
nudH protein networkhttps://string-db.org/network/374463.BCI_0542(Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated [...]
lgt protein networkhttps://string-db.org/network/374463.BCI_0543Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
thyA protein networkhttps://string-db.org/network/374463.BCI_0544Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate ( [...]
recC protein networkhttps://string-db.org/network/374463.BCI_0545Exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dep [...]
recB protein networkhttps://string-db.org/network/374463.BCI_0546Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-depe [...]
recD protein networkhttps://string-db.org/network/374463.BCI_0547Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dep [...]
crp protein networkhttps://string-db.org/network/374463.BCI_0548cAMP-regulatory protein crp; Identified by match to protein family HMM PF00027; match to protein family HMM PF00325.
pabA protein networkhttps://string-db.org/network/374463.BCI_0549Para-aminobenzoate synthase, glutamine amidotransferase component; Identified by similarity to SP:P00903; match to protein family HMM PF00117; match to protein family HMM TIGR00566.
dnaB protein networkhttps://string-db.org/network/374463.BCI_0550Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DN [...]
dnaK protein networkhttps://string-db.org/network/374463.BCI_0552Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
dnaJ protein networkhttps://string-db.org/network/374463.BCI_0553Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an [...]
rpsT protein networkhttps://string-db.org/network/374463.BCI_0554Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
ribF protein networkhttps://string-db.org/network/374463.BCI_0555Riboflavin biosynthesis protein RibF; Identified by match to protein family HMM PF01687; match to protein family HMM PF06574; match to protein family HMM TIGR00083; Belongs to the ribF family.
ileS protein networkhttps://string-db.org/network/374463.BCI_0556isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
lspA protein networkhttps://string-db.org/network/374463.BCI_0557Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
ispH protein networkhttps://string-db.org/network/374463.BCI_05584-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethyl [...]
carA protein networkhttps://string-db.org/network/374463.BCI_0559Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA fam [...]
carB protein networkhttps://string-db.org/network/374463.BCI_0560Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family H [...]
folA protein networkhttps://string-db.org/network/374463.BCI_0561Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
apaH protein networkhttps://string-db.org/network/374463.BCI_0562Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
ksgA protein networkhttps://string-db.org/network/374463.BCI_0563Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a c [...]
pdxA protein networkhttps://string-db.org/network/374463.BCI_05644-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decar [...]
surA protein networkhttps://string-db.org/network/374463.BCI_0565Peptidylprolyl cis-trans isomerase SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation o [...]
smpA protein networkhttps://string-db.org/network/374463.BCI_0566Small protein A; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
BCI_0567 protein networkhttps://string-db.org/network/374463.BCI_0567Conserved hypothetical protein; Identified by match to protein family HMM PF03658; Belongs to the UPF0125 (RnfH) family.
smpB protein networkhttps://string-db.org/network/374463.BCI_0568SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tm [...]
cysQ protein networkhttps://string-db.org/network/374463.BCI_05703'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.
rplI protein networkhttps://string-db.org/network/374463.BCI_0571Ribosomal protein L9; Binds to the 23S rRNA.
rpsR protein networkhttps://string-db.org/network/374463.BCI_0572Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal p [...]
priN protein networkhttps://string-db.org/network/374463.BCI_0573Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.
rpsF protein networkhttps://string-db.org/network/374463.BCI_0574Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
rlmB protein networkhttps://string-db.org/network/374463.BCI_0575RNA methyltransferase, TrmH family, group 3; Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
rnr protein networkhttps://string-db.org/network/374463.BCI_0576Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
purA protein networkhttps://string-db.org/network/374463.BCI_0577Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to t [...]
hflC protein networkhttps://string-db.org/network/374463.BCI_0578HflC protein; HflC and HflK could regulate a protease.
hflK protein networkhttps://string-db.org/network/374463.BCI_0579HflK protein; HflC and HflK could encode or regulate a protease.
hflX protein networkhttps://string-db.org/network/374463.BCI_0580GTP-binding protein hflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPa [...]
hfq protein networkhttps://string-db.org/network/374463.BCI_0581RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in [...]
BCI_0582 protein networkhttps://string-db.org/network/374463.BCI_0582Hypothetical protein; Identified by Glimmer2; putative.
miaA protein networkhttps://string-db.org/network/374463.BCI_0583tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to th [...]
mutL protein networkhttps://string-db.org/network/374463.BCI_0584DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchm [...]
BCI_0585 protein networkhttps://string-db.org/network/374463.BCI_0585N-acetylmuramoyl-l-alanine amidase II; Identified by match to protein family HMM PF01520.
orn protein networkhttps://string-db.org/network/374463.BCI_0586Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
psd protein networkhttps://string-db.org/network/374463.BCI_0587Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
epmA protein networkhttps://string-db.org/network/374463.BCI_0588lysyl-tRNA synthetase-like GenX; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P). Catalyzes the ATP-dependent a [...]
efp protein networkhttps://string-db.org/network/374463.BCI_0589Translation elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, [...]
BCI_0590 protein networkhttps://string-db.org/network/374463.BCI_0590Identified by match to protein family HMM PF04055; match to protein family HMM TIGR00238.
groEL protein networkhttps://string-db.org/network/374463.BCI_0591Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
groES protein networkhttps://string-db.org/network/374463.BCI_0592Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
aspA protein networkhttps://string-db.org/network/374463.BCI_0593Aspartate ammonia-lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00839.
BCI_0595 protein networkhttps://string-db.org/network/374463.BCI_0595Antioxidant, AhpC/TSA family; Identified by match to protein family HMM PF00578.
queA protein networkhttps://string-db.org/network/374463.BCI_0596S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ [...]
tgt protein networkhttps://string-db.org/network/374463.BCI_0597Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in [...]
yajC protein networkhttps://string-db.org/network/374463.BCI_0598Preprotein translocase YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, a [...]
secD protein networkhttps://string-db.org/network/374463.BCI_0599Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete pr [...]
secF protein networkhttps://string-db.org/network/374463.BCI_0600Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete pr [...]
ribD protein networkhttps://string-db.org/network/374463.BCI_0601Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-termi [...]
ribH protein networkhttps://string-db.org/network/374463.BCI_06026,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. [...]
nusB protein networkhttps://string-db.org/network/374463.BCI_0603Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator seque [...]
thiL protein networkhttps://string-db.org/network/374463.BCI_0604Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thi [...]
pgpA protein networkhttps://string-db.org/network/374463.BCI_0605Phosphatidylglycerophosphatase; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
BCI_0606 protein networkhttps://string-db.org/network/374463.BCI_0606Outer membrane protein, OMP85 family; Identified by match to protein family HMM PF01103.
BCI_0607 protein networkhttps://string-db.org/network/374463.BCI_0607Conserved hypothetical protein; Identified by similarity to GB:CAH19693.1; match to protein family HMM PF04357.
ppa protein networkhttps://string-db.org/network/374463.BCI_0608Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
proS protein networkhttps://string-db.org/network/374463.BCI_0609prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
nadK protein networkhttps://string-db.org/network/374463.BCI_0611ATP-dependent NAD Kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2 [...]
grpE protein networkhttps://string-db.org/network/374463.BCI_0612Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nu [...]
ung protein networkhttps://string-db.org/network/374463.BCI_0613uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
nadB protein networkhttps://string-db.org/network/374463.BCI_0614L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
rpoD protein networkhttps://string-db.org/network/374463.BCI_0616RNA polymerase, sigma 70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the pr [...]
dnaG protein networkhttps://string-db.org/network/374463.BCI_0617DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
rpsU protein networkhttps://string-db.org/network/374463.BCI_0618Ribosomal protein S21; Identified by match to protein family HMM PF01165; match to protein family HMM TIGR00030; Belongs to the bacterial ribosomal protein bS21 family.
gcp protein networkhttps://string-db.org/network/374463.BCI_0619O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in t [...]
folB protein networkhttps://string-db.org/network/374463.BCI_0620Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
uppP protein networkhttps://string-db.org/network/374463.BCI_0621Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
cca protein networkhttps://string-db.org/network/374463.BCI_0622tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order [...]
ribB protein networkhttps://string-db.org/network/374463.BCI_06233,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
plsC protein networkhttps://string-db.org/network/374463.BCI_06241-acyl-sn-glycerol-3-phosphate acyltransferase; Identified by similarity to SP:P26647; match to protein family HMM PF01553; match to protein family HMM TIGR00530; Belongs to the 1-acyl-sn-glycero [...]
holD protein networkhttps://string-db.org/network/374463.BCI_0625DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonu [...]
deaD protein networkhttps://string-db.org/network/374463.BCI_0626Inducible ATP-independent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation [...]
pnp protein networkhttps://string-db.org/network/374463.BCI_0627Polynucleotide phosphorylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
rpsO protein networkhttps://string-db.org/network/374463.BCI_0628Ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several [...]
truB protein networkhttps://string-db.org/network/374463.BCI_0629tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
rbfA protein networkhttps://string-db.org/network/374463.BCI_0630Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
infB protein networkhttps://string-db.org/network/374463.BCI_0631Translation initiation factor IF2-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...]
nusA protein networkhttps://string-db.org/network/374463.BCI_0632Transcription termination factor NusA; Participates in both transcription termination and antitermination.
secG protein networkhttps://string-db.org/network/374463.BCI_0635Protein-export membrane protein secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
glmM protein networkhttps://string-db.org/network/374463.BCI_0636Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
folP protein networkhttps://string-db.org/network/374463.BCI_0637Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate [...]
ftsH protein networkhttps://string-db.org/network/374463.BCI_0638ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane [...]
rrmJ protein networkhttps://string-db.org/network/374463.BCI_0639Ribosomal RNA large subunit methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
greA protein networkhttps://string-db.org/network/374463.BCI_0640Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trappi [...]
dacB protein networkhttps://string-db.org/network/374463.BCI_0641D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Identified by match to protein family HMM PF02113; match to protein family HMM TIGR00666.
obg protein networkhttps://string-db.org/network/374463.BCI_0642GTP1/Obg family protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a r [...]
rpmA protein networkhttps://string-db.org/network/374463.BCI_0643Ribosomal protein L27; Identified by match to protein family HMM PF01016; match to protein family HMM TIGR00062; Belongs to the bacterial ribosomal protein bL27 family.
rplU protein networkhttps://string-db.org/network/374463.BCI_0644Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
pgk protein networkhttps://string-db.org/network/374463.BCI_0645Phosphoglycerate kinase; Identified by match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family.
fbaA protein networkhttps://string-db.org/network/374463.BCI_0646Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-b [...]
rpiA protein networkhttps://string-db.org/network/374463.BCI_0647Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
BCI_0648 protein networkhttps://string-db.org/network/374463.BCI_0648Identified by match to protein family HMM PF01812; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
thiD protein networkhttps://string-db.org/network/374463.BCI_0649Phosphomethylpyrimidine kinase; Identified by match to protein family HMM TIGR00097.
guaA protein networkhttps://string-db.org/network/374463.BCI_0650GMP synthetase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.
guaB protein networkhttps://string-db.org/network/374463.BCI_0651Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesi [...]