Organism Overview: Sphaerochaeta coccoides


 
dnaA protein networkhttps://string-db.org/network/760011.Spico_0001Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically doub [...]
AEC01244.1 protein networkhttps://string-db.org/network/760011.Spico_0002DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadi [...]
recF protein networkhttps://string-db.org/network/760011.Spico_0003DNA replication and repair protein recF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-strand [...]
AEC01246.1 protein networkhttps://string-db.org/network/760011.Spico_0004InterPro IPR007922; KEGG: ssm:Spirs_0005 protein of unknown function DUF721; PFAM: Protein of unknown function DUF721/UPF0232; SPTR: Putative uncharacterized protein; IMG reference gene:250395626 [...]
rpmH protein networkhttps://string-db.org/network/760011.Spico_0005HAMAP: Ribosomal protein L34; InterPro IPR000271; KEGG: ssm:Spirs_0006 ribosomal protein L34; PFAM: Ribosomal protein L34; SPTR: 50S ribosomal protein L34; TIGRFAM: Ribosomal protein L34; IMG ref [...]
rnpA protein networkhttps://string-db.org/network/760011.Spico_0006Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. [...]
yidC protein networkhttps://string-db.org/network/760011.Spico_0007Membrane protein oxaA; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that [...]
AEC01250.1 protein networkhttps://string-db.org/network/760011.Spico_0008COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: ssm:Spirs_0009 single-stranded nucleic acid binding R3H domain protein; PFAM: Single-stranded nucleic acid binding R3H; SMART: Single- [...]
AEC01251.1 protein networkhttps://string-db.org/network/760011.Spico_0009Hypothetical protein; COGs: COG0169 Shikimate 5-dehydrogenase; KEGG: art:Arth_1802 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956273.
AEC01252.1 protein networkhttps://string-db.org/network/760011.Spico_0010COGs: COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzyme; InterPro IPR010551; KEGG: art:Arth_1801 glucose-6-phosphate isomerase; PFAM: Glucose-6-phosphate isomerase, pro [...]
AEC01253.1 protein networkhttps://string-db.org/network/760011.Spico_0011COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; KEGG: art:Arth_1808 Zn-dependent hydrolases of the beta-lactamase fold-like protein; SPTR: Zn-dependent hydrolases of the beta-lac [...]
AEC01254.1 protein networkhttps://string-db.org/network/760011.Spico_0012Transcriptional regulator, GntR family with UTRA sensor domain; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: tna:CTN_0371 transcriptional regulator, GntR family; [...]
AEC01255.1 protein networkhttps://string-db.org/network/760011.Spico_0013Sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterPro IPR002078:IPR002197:IPR003593; KEG [...]
AEC01256.1 protein networkhttps://string-db.org/network/760011.Spico_0014Periplasmic binding protein/LacI transcriptional regulator; COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: tle:Tlet_0182 periplasmic binding protein/LacI transcription [...]
AEC01257.1 protein networkhttps://string-db.org/network/760011.Spico_0015COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: csh:Closa_1201 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Monosacchari [...]
AEC01258.1 protein networkhttps://string-db.org/network/760011.Spico_0016Monosaccharide ABC transporter membrane protein, CUT2 family; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: tle:Tlet_ [...]
AEC01259.1 protein networkhttps://string-db.org/network/760011.Spico_0017Xylulokinase; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: bth:BT_4423 xylulose kinase; PFAM: Carbohydrate kinase, FGGY, N-terminal; Carbohydrate kinas [...]
AEC01260.1 protein networkhttps://string-db.org/network/760011.Spico_0018Carbohydrate kinase, FGGY; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: bth:BT_4423 xylulose kinase; PFAM: Carbohydrate kinase, FGGY, N-terminal; Carbo [...]
AEC01261.1 protein networkhttps://string-db.org/network/760011.Spico_0019Hypothetical protein; KEGG: car:cauri_0369 DNA-directed RNA polymerase subunit beta'; SPTR: DNA-directed RNA polymerase subunit beta'; IMG reference gene:2503956283.
AEC01262.1 protein networkhttps://string-db.org/network/760011.Spico_0020COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR023210; KEGG: hoh:Hoch_6537 aldo/keto reductase; PFAM: NADP-dependent oxidoreductase domain; PRIAM: Aryl-alcohol [...]
rbsK protein networkhttps://string-db.org/network/760011.Spico_0021Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histi [...]
AEC01264.1 protein networkhttps://string-db.org/network/760011.Spico_0022Transcriptional regulator, GntR family with UTRA sensor domain; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: lac:LBA0393 transcriptional regulator; PFAM: UbiC tra [...]
AEC01265.1 protein networkhttps://string-db.org/network/760011.Spico_0023COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: tpd:Teth39_2074 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer speci [...]
metK protein networkhttps://string-db.org/network/760011.Spico_0024Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet format [...]
mtnA protein networkhttps://string-db.org/network/760011.Spico_0025Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
AEC01268.1 protein networkhttps://string-db.org/network/760011.Spico_0026PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: ssm:Spirs_4279 PfkB domain protein; PFAM: Carbohydrate/purine kinase; SPTR: Glr0791 protein; IMG refer [...]
murA protein networkhttps://string-db.org/network/760011.Spico_0027UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
AEC01270.1 protein networkhttps://string-db.org/network/760011.Spico_0028Hypothetical protein; IMG reference gene:2503956292.
AEC01271.1 protein networkhttps://string-db.org/network/760011.Spico_0029Sigma 54 interacting domain protein; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR002078:IPR003593; KEGG: dds:Ddes_2345 sigm [...]
AEC01272.1 protein networkhttps://string-db.org/network/760011.Spico_0030KEGG: tva:TVAG_082020 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956294; PFAM: Peptidase family M28.
AEC01273.1 protein networkhttps://string-db.org/network/760011.Spico_0031Uncharacterized protein family UPF0029, Impact, N-terminal protein; COGs: COG1739 conserved hypothetical protein; InterPro IPR001498; KEGG: tde:TDE1321 hypothetical protein; PFAM: Uncharacterised [...]
AEC01274.1 protein networkhttps://string-db.org/network/760011.Spico_0032NUDIX hydrolase; InterPro IPR000086; KEGG: ssm:Spirs_0099 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: MutT family protein, putative 78-dihydro-8-oxoguanine triphosphatase (8-oxo-dGTPase) [...]
AEC01275.1 protein networkhttps://string-db.org/network/760011.Spico_0033KEGG: mpd:MCP_1774 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956297.
AEC01276.1 protein networkhttps://string-db.org/network/760011.Spico_0034COGs: COG0206 Cell division GTPase; InterPro IPR003008; KEGG: cth:Cthe_0445 cell division protein FtsZ; PFAM: Tubulin/FtsZ, GTPase domain; SMART: Tubulin/FtsZ, GTPase domain; SPTR: Cell division [...]
AEC01277.1 protein networkhttps://string-db.org/network/760011.Spico_0035KEGG: pop:POPTR_247422 hypothetical protein; SPTR: Chaperone protein dnaJ; IMG reference gene:2503956299.
deoC protein networkhttps://string-db.org/network/760011.Spico_0036Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB ald [...]
AEC01279.1 protein networkhttps://string-db.org/network/760011.Spico_0037COGs: COG1435 Thymidine kinase; InterPro IPR001267; KEGG: ssm:Spirs_0100 thymidine kinase; PFAM: Thymidine kinase; SPTR: Thymidine kinase; IMG reference gene:2503956301; PFAM: Thymidine kinase; B [...]
AEC01280.1 protein networkhttps://string-db.org/network/760011.Spico_0038Xylose isomerase domain-containing protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: sta:STHERM_c04340 xylose isomerase domain-containing protein TI [...]
AEC01281.1 protein networkhttps://string-db.org/network/760011.Spico_0039Polygalacturonase; COGs: COG5434 Endopygalactorunase; InterPro IPR000743:IPR006626; KEGG: sta:STHERM_c04310 hypothetical protein; PFAM: Glycoside hydrolase, family 28; PRIAM: Polygalacturonase; S [...]
AEC01283.1 protein networkhttps://string-db.org/network/760011.Spico_00412-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: bpb:bpr_I0931 2-keto-3-deoxygluco [...]
AEC01284.1 protein networkhttps://string-db.org/network/760011.Spico_0042PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: ssm:Spirs_3585 PfkB domain protein; PFAM: Carbohydrate/purine kinase; SPTR: KHG/KDPG family aldolase/c [...]
AEC01285.1 protein networkhttps://string-db.org/network/760011.Spico_0043KEGG: bth:BT_3630 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956307.
AEC01286.1 protein networkhttps://string-db.org/network/760011.Spico_0044methylated-DNA/protein- cysteinemethyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the m [...]
AEC01287.1 protein networkhttps://string-db.org/network/760011.Spico_0045Transcriptional regulator, IclR family; COGs: COG1414 Transcriptional regulator; InterPro IPR005471:IPR014757; KEGG: etr:ETAE_1567 pectin degradation repressor; PFAM: Transcription regulator IclR [...]
uxaC protein networkhttps://string-db.org/network/760011.Spico_0046COGs: COG1904 Glucuronate isomerase; HAMAP: Uronate isomerase; InterPro IPR003766; KEGG: ttm:Tthe_2404 glucuronate isomerase; PFAM: Uronate isomerase; PRIAM: Glucuronate isomerase; SPTR: Uronate [...]
AEC01289.1 protein networkhttps://string-db.org/network/760011.Spico_0047COGs: COG2721 Altronate dehydratase; InterPro IPR013974:IPR007392; KEGG: str:Sterm_0691 altronate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase, C-terminal; SAF domain; PRIAM: [...]
AEC01290.1 protein networkhttps://string-db.org/network/760011.Spico_0048Tagaturonate reductase; COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR013131:IPR013118; KEGG: amt:Amet_0555 altronate oxidoreductase; PFAM: Mannitol dehydrogenase, C-ter [...]
AEC01291.1 protein networkhttps://string-db.org/network/760011.Spico_0049Bile acid:sodium symporter; COGs: COG0385 Na+-dependent transporter; InterPro IPR002657; KEGG: bao:BAMF_0163 putative sodium dependent transporter; PFAM: Bile acid:sodium symporter; SPTR: Bile ac [...]
AEC01292.1 protein networkhttps://string-db.org/network/760011.Spico_0050Hypothetical protein; KEGG: bmq:BMQ_1790 putative secreted protein; SPTR: Putative secreted protein; IMG reference gene:2503956314.
AEC01293.1 protein networkhttps://string-db.org/network/760011.Spico_0051Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR011110:IPR000408; KEGG: aeh:Mlg_2688 regulator of chromos [...]
AEC01294.1 protein networkhttps://string-db.org/network/760011.Spico_0052Listeria/Bacterioides repeat-containing protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378:IPR011110:IPR000408; KEGG: aeh:Mlg_2687 regu [...]
AEC01296.1 protein networkhttps://string-db.org/network/760011.Spico_0054Listeria/Bacterioides repeat-containing protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378:IPR011110:IPR000408; KEGG: dal:Dalk_3426 reg [...]
AEC01297.1 protein networkhttps://string-db.org/network/760011.Spico_0055Transcriptional regulator, AraC family; COGs: COG1609 Transcriptional regulators; InterPro IPR001761:IPR000005:IPR018060; KEGG: cag:Cagg_2054 two component transcriptional regulator, AraC family; [...]
AEC01298.1 protein networkhttps://string-db.org/network/760011.Spico_0056Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: mrb:Mrub_0281 binding-protein-de [...]
AEC01299.1 protein networkhttps://string-db.org/network/760011.Spico_0057COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: mrb:Mrub_0280 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-prote [...]
AEC01300.1 protein networkhttps://string-db.org/network/760011.Spico_0058Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: mrb:Mrub_0279 extracellular solute-binding protein fa [...]
AEC01301.1 protein networkhttps://string-db.org/network/760011.Spico_0059Glycosyl hydrolase family 88; COGs: COG4225 unsaturated glucuronyl hydrolase involved in regulation of surface properties and related protein; InterPro IPR010905; KEGG: rmr:Rmar_2470 glycosyl hyd [...]
AEC01302.1 protein networkhttps://string-db.org/network/760011.Spico_0060Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR011110:IPR000408; KEGG: aeh:Mlg_2687 regulator of chromos [...]
AEC01303.1 protein networkhttps://string-db.org/network/760011.Spico_0061Listeria/Bacterioides repeat-containing protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378:IPR000408; KEGG: aeh:Mlg_2687 regulator of c [...]
AEC01304.1 protein networkhttps://string-db.org/network/760011.Spico_0062Nucleoside-binding protein; COGs: COG1744 Uncharacterized ABC-type transport system periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: tde:TDE1950 membrane lipoprotein TmpC, put [...]
AEC01305.1 protein networkhttps://string-db.org/network/760011.Spico_0063Nucleoside ABC transporter ATP-binding protein; COGs: COG3845 ABC-type uncharacterized transport systems ATPase components; InterPro IPR003439:IPR003593; KEGG: tde:TDE1949 ABC transporter, ATP-bi [...]
AEC01306.1 protein networkhttps://string-db.org/network/760011.Spico_0064Nucleoside ABC transporter membrane protein; COGs: COG4603 ABC-type uncharacterized transport system permease component; InterPro IPR001851; KEGG: tde:TDE1948 ABC transporter, permease protein; P [...]
AEC01307.1 protein networkhttps://string-db.org/network/760011.Spico_0065Nucleoside ABC transporter membrane protein; COGs: COG1079 ABC-type transport system permease component; InterPro IPR001851; KEGG: tde:TDE1947 ABC transporter, permease protein; PFAM: ABC transpo [...]
AEC01308.1 protein networkhttps://string-db.org/network/760011.Spico_0066Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molec [...]
AEC01309.1 protein networkhttps://string-db.org/network/760011.Spico_0067Protein of unknown function DUF985; COGs: COG3542 conserved hypothetical protein; InterPro IPR009327; KEGG: sco:SCO4051 hypothetical protein; PFAM: Protein of unknown function DUF985; SPTR: Putat [...]
AEC01310.1 protein networkhttps://string-db.org/network/760011.Spico_00683-oxoacyl-(acyl-carrier-protein) reductase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR020842; KEGG: ssm:Spirs_ [...]
AEC01311.1 protein networkhttps://string-db.org/network/760011.Spico_0069Metallophosphoesterase; COGs: COG2129 phosphoesterase related to the Icc protein; InterPro IPR004843; KEGG: sta:STHERM_c06590 Ser/Thr protein phosphatase family protein; PFAM: Metallo-dependent p [...]
AEC01312.1 protein networkhttps://string-db.org/network/760011.Spico_0070KEGG: ssm:Spirs_2366 hypothetical protein; SPTR: Transcriptional regulator; IMG reference gene:2503956334.
AEC01313.1 protein networkhttps://string-db.org/network/760011.Spico_0071KEGG: cdf:CD1458 putative flavoprotein; SPTR: Probable flavoprotein; IMG reference gene:2503956335; PFAM: NADPH-dependent FMN reductase.
AEC01314.1 protein networkhttps://string-db.org/network/760011.Spico_0072ABC transporter related protein; COGs: COG1119 ABC-type molybdenum transport system ATPase component/photorepair protein PhrA; InterPro IPR003439:IPR003593; KEGG: mma:MM_0570 ABC transporter, ATP [...]
AEC01315.1 protein networkhttps://string-db.org/network/760011.Spico_0073Regulatory protein GntR HTH; COGs: COG2186 Transcriptional regulators; InterPro IPR000524; KEGG: ssm:Spirs_1347 GntR domain protein; PFAM: HTH transcriptional regulator, GntR; SMART: HTH transcri [...]
AEC01316.1 protein networkhttps://string-db.org/network/760011.Spico_0074Hypothetical protein; IMG reference gene:2503956338.
AEC01317.1 protein networkhttps://string-db.org/network/760011.Spico_0075Hypothetical protein; KEGG: tgu:100225112 similar to ARID4B variant protein; SPTR: Type I secretion outer membrane protein, TolC family; IMG reference gene:2503956339.
AEC01318.1 protein networkhttps://string-db.org/network/760011.Spico_0076COGs: COG1760 L-serine deaminase; InterPro IPR005131:IPR005130; KEGG: bfs:BF1216 putative L-serine dehydratase; PFAM: Serine dehydratase-like, alpha subunit; Serine dehydratase beta chain; PRIAM: [...]
AEC01319.1 protein networkhttps://string-db.org/network/760011.Spico_0077Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: ssm:Spirs_0788 transcriptional regulator, LacI family; PFAM: HTH transcriptio [...]
AEC01320.1 protein networkhttps://string-db.org/network/760011.Spico_0078Periplasmic binding protein/LacI transcriptional regulator; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: ssm:Spirs_1666 periplasmic binding prote [...]
AEC01321.1 protein networkhttps://string-db.org/network/760011.Spico_0079Monosaccharide ABC transporter membrane protein, CUT2 family; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: ssm:Spirs [...]
AEC01322.1 protein networkhttps://string-db.org/network/760011.Spico_0080Inositol 2-dehydrogenase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: ssm:Spirs_1664 oxidoreductase domain protein; PFAM: Oxidoreductase, N-terminal; Oxid [...]
AEC01323.1 protein networkhttps://string-db.org/network/760011.Spico_0081Monosaccharide ABC transporter ATP-binding protein, CUT2 family; COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: ssm:Spirs_1663 ABC transporter [...]
AEC01324.1 protein networkhttps://string-db.org/network/760011.Spico_0082Myo-inositol 2-dehydrogenase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: kol:Kole_0987 oxidoreductase domain protein; PFAM: Oxidoreductase, N-terminal; O [...]
AEC01325.1 protein networkhttps://string-db.org/network/760011.Spico_0083Myo-inositol catabolism IolB domain protein; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: kol:Kole_0990 myo-inositol catabolism IolB domain protein; SPTR: Myo-inos [...]
AEC01326.1 protein networkhttps://string-db.org/network/760011.Spico_00843D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COGs: COG3962 Acetolactate synthase; InterPro IPR012001:IPR012000:IPR011766; KEGG: ssm:Spirs_2987 thiamine pyrophosphate protein domain prote [...]
AEC01327.1 protein networkhttps://string-db.org/network/760011.Spico_00852-keto-myo-inositol dehydratase; COGs: COG1082 Sugar phosphate isomerase/epimerase; HAMAP: Inosose dehydratase; InterPro IPR012307; KEGG: str:Sterm_4013 myo-inosose-2 dehydratase; PFAM: Xylose is [...]
AEC01328.1 protein networkhttps://string-db.org/network/760011.Spico_0086COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR006436:IPR005106:IPR020829:IPR020828; KEGG: ssm:Spirs_0990 glyceraldehyde-3-phosphate dehyd [...]
AEC01329.1 protein networkhttps://string-db.org/network/760011.Spico_0087COGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576; KEGG: ssm:Spirs_0989 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate ki [...]
AEC01330.1 protein networkhttps://string-db.org/network/760011.Spico_0088Protein of unknown function DUF2088; COGs: COG3875 conserved hypothetical protein; InterPro IPR018657; KEGG: ssm:Spirs_0988 protein of unknown function DUF2088; PFAM: Protein of unknown function [...]
leuS protein networkhttps://string-db.org/network/760011.Spico_0089COGs: COG0495 Leucyl-tRNA synthetase; InterPro IPR002302:IPR015413:IPR013155; KEGG: ssm:Spirs_0283 leucyl-tRNA synthetase; PFAM: Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding [...]
AEC01332.1 protein networkhttps://string-db.org/network/760011.Spico_0090Filamentation induced by cAMP protein Fic; COGs: COG3177 conserved hypothetical protein; InterPro IPR003812; KEGG: afn:Acfer_1163 filamentation induced by cAMP protein Fic; PFAM: Filamentation in [...]
AEC01333.1 protein networkhttps://string-db.org/network/760011.Spico_0091COGs: COG2116 Formate/nitrite family of transporter; InterPro IPR000292; KEGG: str:Sterm_3165 formate/nitrite transporter; PFAM: Formate/nitrite transporter; SPTR: Formate/nitrite transporter; IM [...]
rlmE protein networkhttps://string-db.org/network/760011.Spico_0092Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
AEC01335.1 protein networkhttps://string-db.org/network/760011.Spico_0093Cobalamin synthesis protein P47K; COGs: COG0523 Putative GTPase (G3E family); InterPro IPR003495:IPR011629; KEGG: bur:Bcep18194_A3246 cobalamin synthesis protein/P47K; PFAM: Cobalamin (vitamin B1 [...]
AEC01336.1 protein networkhttps://string-db.org/network/760011.Spico_0094Glucokinase; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: eat:EAT1b_0550 glucokinase, ROK family; PFAM: ROK; PRIAM: Glucokinase; SPTR: Glucokinase, ROK family; [...]
AEC01337.1 protein networkhttps://string-db.org/network/760011.Spico_0095COGs: COG1882 Pyruvate-formate lyase; InterPro IPR010098:IPR004184:IPR001150; KEGG: cbe:Cbei_0705 pyruvate formate-lyase; PFAM: Pyruvate formate-lyase, PFL; Formate C-acetyltransferase glycine ra [...]
AEC01338.1 protein networkhttps://string-db.org/network/760011.Spico_0096Transcriptional regulator, DeoR family; COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036; KEGG: cbl:CLK_0642 putative HTH-type transcriptional regulator [...]
AEC01339.1 protein networkhttps://string-db.org/network/760011.Spico_0097Bifunctional carbohydrate binding and transport protein; COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: pin:Ping_2790 bifunctional carbohydrate binding and transport p [...]
AEC01340.1 protein networkhttps://string-db.org/network/760011.Spico_0098COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: dtu:Dtur_1644 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transp [...]
AEC01341.1 protein networkhttps://string-db.org/network/760011.Spico_0099Inner-membrane translocator; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: cbk:CLL_A1530 ribose transport system perm [...]
AEC01342.1 protein networkhttps://string-db.org/network/760011.Spico_0100Inner-membrane translocator; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: pmu:PM0154 ribose ABC transporter permease [...]
AEC01343.1 protein networkhttps://string-db.org/network/760011.Spico_0101Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: tit:Thit_2113 transcriptional regulator, LacI family; PFAM: HTH transcription [...]
AEC01344.1 protein networkhttps://string-db.org/network/760011.Spico_0102Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: pjd:Pjdr2_4722 oxidoreductase domain protein; PFAM: Oxidoreductase, N-terminal; [...]
AEC01345.1 protein networkhttps://string-db.org/network/760011.Spico_0103Hypothetical protein; KEGG: cel:T01G9.5 defective MEIosis family member (mei-1); SPTR: Meiotic spindle formation protein mei-1; IMG reference gene:2503956367.
AEC01346.1 protein networkhttps://string-db.org/network/760011.Spico_0104Glycyl-radical enzyme activating protein family; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR012839:IPR007197:IPR001450; KEGG: clj:CLJU_c25970 pyruvate formate-lyase activ [...]
AEC01347.1 protein networkhttps://string-db.org/network/760011.Spico_0105COGs: COG1882 Pyruvate-formate lyase; InterPro IPR010098:IPR004184:IPR001150; KEGG: clj:CLJU_c25980 pyruvate formate-lyase; PFAM: Pyruvate formate-lyase, PFL; Formate C-acetyltransferase glycine [...]
AEC01348.1 protein networkhttps://string-db.org/network/760011.Spico_0106Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: gym:GYMC10_4683 transcriptional regulator, AraC family; [...]
AEC01349.1 protein networkhttps://string-db.org/network/760011.Spico_0107Extracellular ligand-binding receptor; COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: tde:TDE2361 high-affinity branched chain [...]
AEC01350.1 protein networkhttps://string-db.org/network/760011.Spico_0108Inner-membrane translocator; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: tde:TDE2366 high-affinity branched-chain amino acid A [...]
AEC01351.1 protein networkhttps://string-db.org/network/760011.Spico_0109Inner-membrane translocator; COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: tde:TDE2365 high-affinity branched-chain amino acid AB [...]
AEC01352.1 protein networkhttps://string-db.org/network/760011.Spico_0110Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family; COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: bts:B [...]
AEC01353.1 protein networkhttps://string-db.org/network/760011.Spico_0111ABC transporter related protein; COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: dhd:Dhaf_4922 ABC transporter related; PF [...]
AEC01354.1 protein networkhttps://string-db.org/network/760011.Spico_0112Hypothetical protein; KEGG: aco:Amico_0456 uroporphyrinogen decarboxylase; SPTR: Uroporphyrinogen decarboxylase; IMG reference gene:2503956376; PFAM: Uroporphyrinogen decarboxylase (URO-D); Belon [...]
AEC01355.1 protein networkhttps://string-db.org/network/760011.Spico_0113UPF0597 protein yhaM; COGs: COG3681 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0597; InterPro IPR021144; KEGG: cpy:Cphy_1256 hypothetical protein; SPTR: UPF0597 prot [...]
aroE protein networkhttps://string-db.org/network/760011.Spico_0114Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshiki [...]
AEC01357.1 protein networkhttps://string-db.org/network/760011.Spico_0115Glycyl-radical enzyme activating protein family; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR012839:IPR007197; KEGG: ssa:SSA_0277 pyruvate formate-lyase 3, putative; PFAM: [...]
AEC01358.1 protein networkhttps://string-db.org/network/760011.Spico_0116Peptidase S54, rhomboid domain protein; COGs: COG0705 membrane protein; InterPro IPR022764; KEGG: sta:STHERM_c21730 rhomboid family protein; PFAM: Peptidase S54, rhomboid domain; SPTR: Rhomboid f [...]
AEC01359.1 protein networkhttps://string-db.org/network/760011.Spico_0117COGs: COG1816 Adenosine deaminase; HAMAP: Adenosine deaminase; InterPro IPR006330:IPR001365; KEGG: ssm:Spirs_0300 adenosine deaminase; PFAM: Adenosine/AMP deaminase; PRIAM: Adenosine deaminase; S [...]
AEC01360.1 protein networkhttps://string-db.org/network/760011.Spico_0118Ankyrin; InterPro IPR002110; KEGG: wpi:WPa_1379 ankyrin repeat domain protein; PFAM: Ankyrin repeat; SPTR: FOG: Ankyrin repeat; IMG reference gene:2503956382; PFAM: Ankyrin repeat.
proS protein networkhttps://string-db.org/network/760011.Spico_0119Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
AEC01362.1 protein networkhttps://string-db.org/network/760011.Spico_0120Class II aldolase/adducin family protein; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: ssm:Spirs_2391 class II aldolase/adducin fam [...]
AEC01363.1 protein networkhttps://string-db.org/network/760011.Spico_0121COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: ssm:Spirs_2992 transketolase domain protein; PFAM: Transketolase, N-terminal; PRIAM: Transketolase; SPTR: Transketolase d [...]
AEC01364.1 protein networkhttps://string-db.org/network/760011.Spico_01221-deoxy-D-xylulose-5-phosphate synthase; COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR005475:IPR005476; KEGG: ssm:Spirs_2991 transketolase domain protein; PFAM: Transketolase-like, [...]
AEC01365.1 protein networkhttps://string-db.org/network/760011.Spico_0124KEGG: aag:AaeL_AAEL003101 hypothetical protein; SPTR: Suppression of copper sensitivity: lipoprotein modification in; IMG reference gene:2503956388.
AEC01366.1 protein networkhttps://string-db.org/network/760011.Spico_0125OsmC family protein; COGs: COG1765 redox protein regulator of disulfide bond formation; InterPro IPR003718; KEGG: tsi:TSIB_1698 predicted stress-inducible protein, OsmC/Ohr family; PFAM: Peroxire [...]
aspS protein networkhttps://string-db.org/network/760011.Spico_0126aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: [...]
AEC01369.1 protein networkhttps://string-db.org/network/760011.Spico_0129Hypothetical protein; KEGG: lth:KLTH0C00440g KLTH0C00440p; SPTR: Uncharacterized Fe-S protein; IMG reference gene:2503956393.
AEC01370.1 protein networkhttps://string-db.org/network/760011.Spico_0130KEGG: lhk:LHK_01554 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956394.
AEC01371.1 protein networkhttps://string-db.org/network/760011.Spico_0132KEGG: pdi:BDI_2608 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956396.
AEC01372.1 protein networkhttps://string-db.org/network/760011.Spico_0133COGs: COG2865 transcriptional regulator protein; InterPro IPR007421; KEGG: mpe:MYPE2570 hypothetical protein; PFAM: ATPase, AAA-4; SPTR: Putative DNA recombinase RecG; IMG reference gene:25039563 [...]
AEC01373.1 protein networkhttps://string-db.org/network/760011.Spico_0135KEGG: zpr:ZPR_4496 membrane protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956399; PFAM: Bacterial protein of unknown function (DUF939).
AEC01374.1 protein networkhttps://string-db.org/network/760011.Spico_0136Appr-1-p processing domain protein; COGs: COG2110 phosphatase homologous to the C-terminal domain of histone macroH2A1; InterPro IPR002589; KEGG: aco:Amico_1593 Appr-1-p processing domain protein [...]
AEC01375.1 protein networkhttps://string-db.org/network/760011.Spico_0137KEGG: bha:BH1197 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956401.
AEC01376.1 protein networkhttps://string-db.org/network/760011.Spico_0138PspC domain protein; InterPro IPR007168; KEGG: dbr:Deba_2761 phage shock protein C, PspC; PFAM: Phage shock domain; SPTR: Putative phage shock protein C; IMG reference gene:2503956402; PFAM: PspC [...]
AEC01377.1 protein networkhttps://string-db.org/network/760011.Spico_0139Hypothetical protein; KEGG: gdj:Gdia_0837 methyl-accepting chemotaxis sensory transducer; SPTR: Predicted protein; IMG reference gene:2503956403.
AEC01378.1 protein networkhttps://string-db.org/network/760011.Spico_0140COGs: COG1842 Phage shock protein A (IM30) suppresses sigma54-dependent transcription; InterPro IPR007157; KEGG: dde:Dde_3226 phage shock protein A; PFAM: PspA/IM30; SPTR: Phage shock protein A; [...]
AEC01379.1 protein networkhttps://string-db.org/network/760011.Spico_0141Sigma 54 interacting domain protein; COGs: COG3604 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterPro IPR014317:IPR002078:IPR003593; KEGG: dbr:Deba_2764 si [...]
AEC01380.1 protein networkhttps://string-db.org/network/760011.Spico_0142PspC domain protein; InterPro IPR007168; KEGG: dma:DMR_38290 hypothetical membrane protein; PFAM: Phage shock domain; SPTR: Phage shock protein C, PspC; IMG reference gene:2503956406; PFAM: PspC [...]
AEC01381.1 protein networkhttps://string-db.org/network/760011.Spico_0143COGs: COG1842 Phage shock protein A (IM30) suppresses sigma54-dependent transcription; InterPro IPR007157; KEGG: dvm:DvMF_1799 phage shock protein A, PspA; PFAM: PspA/IM30; SPTR: Phage shock prot [...]
rsmI protein networkhttps://string-db.org/network/760011.Spico_0144Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
AEC01383.1 protein networkhttps://string-db.org/network/760011.Spico_0145tRNA/rRNA methyltransferase (SpoU); COGs: COG0566 rRNA methylase; InterPro IPR001537; KEGG: ssm:Spirs_0318 tRNA/rRNA methyltransferase (SpoU); PFAM: tRNA/rRNA methyltransferase, SpoU; SPTR: RNA m [...]
AEC01384.1 protein networkhttps://string-db.org/network/760011.Spico_0146Peptidase S16 lon domain protein; COGs: COG1067 ATP-dependent protease; KEGG: ssm:Spirs_0321 peptidase S16 lon domain protein; SPTR: Putative uncharacterized protein; manually curated; IMG refere [...]
AEC01385.1 protein networkhttps://string-db.org/network/760011.Spico_0147NGG1p interacting factor 3 protein, NIF3; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: tde:TDE2208 hypothetical protein; PFAM: NGG1p interacting factor 3, NIF3; SPTR: P [...]
lspA protein networkhttps://string-db.org/network/760011.Spico_0148Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
AEC01387.1 protein networkhttps://string-db.org/network/760011.Spico_0149KEGG: ssm:Spirs_0324 leader peptide processing enzyme; SPTR: Putative uncharacterized protein; IMG reference gene:2503956413.
AEC01388.1 protein networkhttps://string-db.org/network/760011.Spico_0150KEGG: lic:LIC11034 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956414.
AEC01389.1 protein networkhttps://string-db.org/network/760011.Spico_0151KEGG: fjo:Fjoh_0934 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956415.
AEC01390.1 protein networkhttps://string-db.org/network/760011.Spico_0152Hypothetical protein; COGs: COG0657 Esterase/lipase; InterPro IPR013094; KEGG: amr:AM1_0524 lipase/esterase, putative; SPTR: Lipase/esterase, putative; IMG reference gene:2503956416; PFAM: alpha/ [...]
AEC01391.1 protein networkhttps://string-db.org/network/760011.Spico_0153KEGG: taf:THA_161 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956417.
AEC01392.1 protein networkhttps://string-db.org/network/760011.Spico_0154Transcriptional regulator, AraC family; COGs: COG2706 3-carboxymuconate cyclase; InterPro IPR003313:IPR000005:IPR019405:IPR018060; KEGG: ssm:Spirs_3785 transcriptional regulator, AraC family; PFA [...]
xylB protein networkhttps://string-db.org/network/760011.Spico_0155Xylulokinase; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR006000:IPR018484:IPR018485; KEGG: xca:xccb100_2505 xylulokinase; PFAM: Carbohydrate kinase, FGGY, N-terminal; Carboh [...]
xylA protein networkhttps://string-db.org/network/760011.Spico_0156COGs: COG2115 Xylose isomerase; HAMAP: Xylose isomerase; InterPro IPR013452:IPR001998:IPR012307; KEGG: ssm:Spirs_3786 xylose isomerase; PFAM: Xylose isomerase, TIM barrel domain; PRIAM: Xylose is [...]
AEC01395.1 protein networkhttps://string-db.org/network/760011.Spico_0157Pectinesterase; COGs: COG4677 Pectin methylesterase; InterPro IPR000070; KEGG: rmr:Rmar_2469 pectinesterase; PFAM: Pectinesterase, catalytic; PRIAM: Pectinesterase; SPTR: Pectinesterase; IMG refe [...]
AEC01396.1 protein networkhttps://string-db.org/network/760011.Spico_0158COGs: COG1785 Alkaline phosphatase; InterPro IPR001952; KEGG: avi:Avi_0605 alkaline phosphatase; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase; IMG reference [...]
AEC01397.1 protein networkhttps://string-db.org/network/760011.Spico_0159KEGG: rru:Rru_A1290 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956423.
AEC01398.1 protein networkhttps://string-db.org/network/760011.Spico_0160Phosphonate-transporting ATPase; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: pct:PC1_3918 ABC transporter related; PFAM: AB [...]
AEC01399.1 protein networkhttps://string-db.org/network/760011.Spico_0161Protein of unknown function DUF214; InterPro IPR003838; KEGG: rru:Rru_A1292 hypothetical protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Putative uncharacterized [...]
AEC01400.1 protein networkhttps://string-db.org/network/760011.Spico_0162Protein of unknown function DUF21; COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR002550:IPR000644:IPR005170; KEGG: cth:Cthe_2870 hypothetical protein; PFAM: Dom [...]
AEC01401.1 protein networkhttps://string-db.org/network/760011.Spico_0163COGs: COG1392 Phosphate transport regulator (distant homolog of PhoU); InterPro IPR018445; KEGG: cce:Ccel_2118 protein of unknown function DUF47; PFAM: Putitive phosphate transport regulator; SPT [...]
AEC01402.1 protein networkhttps://string-db.org/network/760011.Spico_0164COGs: COG0306 Phosphate/sulphate permease; InterPro IPR001204; KEGG: efa:EF2442 phosphate transporter family protein; PFAM: Phosphate transporter; SPTR: Phosphate transporter family protein; IMG [...]
AEC01403.1 protein networkhttps://string-db.org/network/760011.Spico_0165Protein of unknown function DUF6 transmembrane; COGs: COG2510 membrane protein; InterPro IPR000620; KEGG: cpy:Cphy_2870 hypothetical protein; PFAM: Drug/metabolite transporter; SPTR: Putative unc [...]
AEC01404.1 protein networkhttps://string-db.org/network/760011.Spico_0166KEGG: hor:Hore_08230 WD40 domain protein beta propeller; SPTR: WD40 domain protein beta Propeller; IMG reference gene:2503956430; PFAM: WD40-like Beta Propeller Repeat.
AEC01405.1 protein networkhttps://string-db.org/network/760011.Spico_0167Protein of unknown function DUF156; COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: apr:Apre_0988 protein of unknown function DUF156; PFAM: Protein of unknown function DUF [...]
AEC01406.1 protein networkhttps://string-db.org/network/760011.Spico_0168Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR011110:IPR000408; KEGG: aeh:Mlg_2687 regulator of chromos [...]
AEC01407.1 protein networkhttps://string-db.org/network/760011.Spico_0169Hypothetical protein; IMG reference gene:2503956433.
AEC01408.1 protein networkhttps://string-db.org/network/760011.Spico_0170Phospholipid/glycerol acyltransferase; InterPro IPR002123; KEGG: pgi:PG1876 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SPTR: Acyltransferase protein; IMG reference gene:25 [...]
AEC01409.1 protein networkhttps://string-db.org/network/760011.Spico_0171COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140:IPR003439:IPR003593; KEGG: ppy:PPE_00122 hypothetical ABC transporter ATP-binding protein; PFA [...]
AEC01410.1 protein networkhttps://string-db.org/network/760011.Spico_0172COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140:IPR003439:IPR003593; KEGG: ppy:PPE_00123 ABC-type multidrug transport system protein; PFAM: AB [...]
AEC01411.1 protein networkhttps://string-db.org/network/760011.Spico_0173Carbohydrate ABC transporter substrate-binding protein, CUT1 family; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: ssm:Spirs_1368 extracellular so [...]
AEC01412.1 protein networkhttps://string-db.org/network/760011.Spico_0174Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ssm:Spirs_1367 binding-protein-dependen [...]
AEC01413.1 protein networkhttps://string-db.org/network/760011.Spico_0175Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: ssm:Spirs_1366 binding-protein-dependent [...]
AEC01414.1 protein networkhttps://string-db.org/network/760011.Spico_0176HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR006402:IPR005834; KEGG: ssm:Spirs_1365 HAD-superfamily hydrolase, subfamily IA, variant [...]
AEC01415.1 protein networkhttps://string-db.org/network/760011.Spico_0177Two component transcriptional regulator, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR000005:IPR01806 [...]
AEC01416.1 protein networkhttps://string-db.org/network/760011.Spico_0178Integral membrane sensor signal transduction histidine kinase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR010559:IPR003594; KEGG: ssm:Spirs_1 [...]
AEC01417.1 protein networkhttps://string-db.org/network/760011.Spico_0179KEGG: cth:Cthe_1655 hypothetical protein; SPTR: Predicted transcriptional regulator; IMG reference gene:2503956443.
AEC01418.1 protein networkhttps://string-db.org/network/760011.Spico_0180KEGG: prw:PsycPRwf_1121 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956444.
AEC01419.1 protein networkhttps://string-db.org/network/760011.Spico_0181Helicase A859L; InterPro IPR006935:IPR011639:IPR018306:IPR014001; KEGG: spr:spr1101 type II restriction endonuclease, putative; SMART: Bacteriophage T5, ORF172 DNA-binding; DEAD-like helicase, N- [...]
AEC01420.1 protein networkhttps://string-db.org/network/760011.Spico_0182Filamentation induced by cAMP protein Fic; COGs: COG3177 conserved hypothetical protein; InterPro IPR003812; KEGG: dsy:DSY0678 hypothetical protein; PFAM: Filamentation induced by cAMP/death on c [...]
AEC01421.1 protein networkhttps://string-db.org/network/760011.Spico_0183KEGG: dhd:Dhaf_4948 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956447.
AEC01422.1 protein networkhttps://string-db.org/network/760011.Spico_0184KEGG: bln:Blon_0974 HipA domain protein; SPTR: HipA-like C-terminal domain; IMG reference gene:2503956448.
AEC01423.1 protein networkhttps://string-db.org/network/760011.Spico_0185Addiction module toxin, RelE/StbE family; COGs: COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system; InterPro IPR012753:IPR007712; KEGG: esi:Exig_1264 addiction module a [...]
AEC01424.1 protein networkhttps://string-db.org/network/760011.Spico_0186KEGG: fnu:FN1099 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956450; PFAM: Ribbon-helix-helix protein, copG family.
AEC01425.1 protein networkhttps://string-db.org/network/760011.Spico_0187Hypothetical protein; IMG reference gene:2503956451.
AEC01427.1 protein networkhttps://string-db.org/network/760011.Spico_0190KEGG: bcl:ABC1165 cell surface protein; SPTR: Cell surface protein; IMG reference gene:2503956455.
AEC01428.1 protein networkhttps://string-db.org/network/760011.Spico_0191UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: bbr:BB4600 ATP-dependent DNA helicase; PFAM: DNA helicase, UvrD/REP type; SPTR: Putative uncharacter [...]
AEC01429.1 protein networkhttps://string-db.org/network/760011.Spico_0192KEGG: fnu:FN0210 CopG family transcriptional regulator; SPTR: Toxin-antitoxin system protein; IMG reference gene:2503956457.
AEC01430.1 protein networkhttps://string-db.org/network/760011.Spico_0193Addiction module toxin, RelE/StbE family; COGs: COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system; InterPro IPR012753:IPR007712; KEGG: esi:Exig_1264 addiction module a [...]
AEC01431.1 protein networkhttps://string-db.org/network/760011.Spico_0194Filamentation induced by cAMP protein Fic; COGs: COG3177 conserved hypothetical protein; InterPro IPR003812; KEGG: hmo:HM1_0044 fic family protein, putative; PFAM: Filamentation induced by cAMP/d [...]
AEC01432.1 protein networkhttps://string-db.org/network/760011.Spico_0195KEGG: afn:Acfer_1116 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956460.
AEC01433.1 protein networkhttps://string-db.org/network/760011.Spico_0197KEGG: cbr:CBG18870 Hypothetical protein CBG18870; SPTR: Putative uncharacterized protein; IMG reference gene:2503956462.
AEC01434.1 protein networkhttps://string-db.org/network/760011.Spico_0198KEGG: ele:Elen_0127 DNA binding domain protein, excisionase family; SPTR: Putative uncharacterized protein; IMG reference gene:2503956463; PFAM: HipA-like C-terminal domain.
AEC01435.1 protein networkhttps://string-db.org/network/760011.Spico_0199Hypothetical protein; IMG reference gene:2503956464.
AEC01436.1 protein networkhttps://string-db.org/network/760011.Spico_0201Protein of unknown function DUF891; InterPro IPR009241; KEGG: ere:EUBREC_3676 hypothetical protein; PFAM: Protein of unknown function DUF891; SPTR: Toxin-antitoxin system, toxin component, RelE f [...]
AEC01437.1 protein networkhttps://string-db.org/network/760011.Spico_0202Helix-turn-helix domain protein; InterPro IPR001387; KEGG: ere:EUBREC_3010 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator, XR [...]
AEC01438.1 protein networkhttps://string-db.org/network/760011.Spico_0203Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: ssm:Spirs_1023 aminotransferase class I and II; PFAM: Aminotransferase, clas [...]
AEC01439.1 protein networkhttps://string-db.org/network/760011.Spico_02045-carboxymethyl-2-hydroxymuconate Delta-isomerase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: mta:Moth_149 [...]
AEC01440.1 protein networkhttps://string-db.org/network/760011.Spico_0205LemA family protein; COGs: COG1704 conserved hypothetical protein; InterPro IPR007156; KEGG: ddf:DEFDS_1131 hypothetical protein; PFAM: LemA; SPTR: Putative uncharacterized protein; IMG reference [...]
AEC01441.1 protein networkhttps://string-db.org/network/760011.Spico_0206InterPro IPR018702; KEGG: nde:NIDE3501 hypothetical protein; PFAM: Protein of unknown function DUF2207, membrane; SPTR: Putative uncharacterized protein; IMG reference gene:2503956471; PFAM: Pred [...]
AEC01443.1 protein networkhttps://string-db.org/network/760011.Spico_0208KEGG: pla:Plav_0415 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956473; PFAM: Protein of unknown function (DUF2804).
AEC01444.1 protein networkhttps://string-db.org/network/760011.Spico_0209COGs: COG0724 RNA-binding protein (RRM domain); InterPro IPR000504; KEGG: ssm:Spirs_2330 RNP-1 like RNA-binding protein; PFAM: RNA recognition motif domain; SMART: RNA recognition motif domain; S [...]
AEC01445.1 protein networkhttps://string-db.org/network/760011.Spico_0210Phosphatidate cytidylyltransferase; InterPro IPR000374; KEGG: acl:ACL_1417 integral membrane protein; PFAM: Phosphatidate cytidylyltransferase; SPTR: Integral membrane protein; IMG reference gene [...]
AEC01446.1 protein networkhttps://string-db.org/network/760011.Spico_0211COGs: COG1836 membrane protein; InterPro IPR002794; KEGG: gct:GC56T3_1039 protein of unknown function DUF92 transmembrane; PFAM: Protein of unknown function DUF92, TMEM19; SPTR: Putative uncharac [...]
groL protein networkhttps://string-db.org/network/760011.Spico_021260 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
yajC protein networkhttps://string-db.org/network/760011.Spico_0213Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into mem [...]
AEC01449.1 protein networkhttps://string-db.org/network/760011.Spico_0214COGs: COG0342 Preprotein translocase subunit SecD; KEGG: ssm:Spirs_3237 protein-export membrane protein SecD; SPTR: Putative uncharacterized protein; IMG reference gene:2503956479; PFAM: Protein [...]
ispH protein networkhttps://string-db.org/network/760011.Spico_02164-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethyl [...]
rex protein networkhttps://string-db.org/network/760011.Spico_0217Redox-sensing transcriptional repressor rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
AEC01452.1 protein networkhttps://string-db.org/network/760011.Spico_0218COGs: COG1956 GAF domain-containing protein; InterPro IPR003018; KEGG: bpu:BPUM_2609 hypothetical protein; PFAM: GAF; SPTR: Hypothetical GAF domain protein; IMG reference gene:2503956483; PFAM: G [...]
thrS protein networkhttps://string-db.org/network/760011.Spico_0219Ser-tRNA(Thr) hydrolase; COGs: COG0441 Threonyl-tRNA synthetase; InterPro IPR002320:IPR012947:IPR002314:IPR004154; KEGG: ssm:Spirs_3229 threonyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, [...]
AEC01454.1 protein networkhttps://string-db.org/network/760011.Spico_0220Carboxypeptidase Taq; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.
AEC01455.1 protein networkhttps://string-db.org/network/760011.Spico_0221CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR004570:IPR000462; KEGG: ssm:Spirs_3225 CDP-diacylglycerol/glyce [...]
AEC01456.1 protein networkhttps://string-db.org/network/760011.Spico_0222InterPro IPR006379; KEGG: ssm:Spirs_3224 HAD-superfamily hydrolase, subfamily IIB; SPTR: Putative hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; IMG reference gene:2503956487; TIGR [...]
AEC01457.1 protein networkhttps://string-db.org/network/760011.Spico_0223ABC-3 protein; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: dsy:DSY0105 hypothetical protein; PFAM: ABC-3; SPTR: Putative uncharacterized prot [...]
AEC01458.1 protein networkhttps://string-db.org/network/760011.Spico_0224Fe(3+)-transporting ATPase; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: dhd:Dhaf_0043 ABC transporter related; PFAM: ABC transporter-like; [...]
metN protein networkhttps://string-db.org/network/760011.Spico_0225Sulfate-transporting ATPase; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
AEC01460.1 protein networkhttps://string-db.org/network/760011.Spico_0226COGs: COG2011 ABC-type metal ion transport system permease component; InterPro IPR000515; KEGG: fsu:Fisuc_1035 binding-protein-dependent transport systems inner membrane component; PFAM: Binding- [...]
AEC01461.1 protein networkhttps://string-db.org/network/760011.Spico_0227NLPA lipoprotein; COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872; KEGG: fsu:Fisuc_1037 NlpA lipoprotein; PFAM: NLPA lipoprotein; SPTR: [...]
AEC01462.1 protein networkhttps://string-db.org/network/760011.Spico_0228RmuC-domain protein; COGs: COG1322 conserved hypothetical protein; InterPro IPR003798; KEGG: bgl:bglu_1g09340 RmuC domain protein; PFAM: DNA recombination RmuC; SPTR: Putative uncharacterized pro [...]
arcB protein networkhttps://string-db.org/network/760011.Spico_0229Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs t [...]
AEC01464.1 protein networkhttps://string-db.org/network/760011.Spico_0230Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR011110:IPR000408; KEGG: aeh:Mlg_2687 regulator of chromos [...]
AEC01465.1 protein networkhttps://string-db.org/network/760011.Spico_0231Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR000408; KEGG: aeh:Mlg_2687 regulator of chromosome conden [...]
AEC01466.1 protein networkhttps://string-db.org/network/760011.Spico_0232COGs: COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); InterPro IPR008331; KEGG: tpp:TPASS_1038 bacterioferrin TpF1; PFAM: Ferritin/Dps protein; SPTR: Antigen TyF1; IMG re [...]
AEC01467.1 protein networkhttps://string-db.org/network/760011.Spico_0233Transcriptional regulator, NifA subfamily, Fis Family; COGs: COG3604 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterPro IPR003018:IPR002078:IPR002197:IPR00 [...]
clpB protein networkhttps://string-db.org/network/760011.Spico_0234ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belong [...]
AEC01469.1 protein networkhttps://string-db.org/network/760011.Spico_0235Protein of unknown function DUF554; COGs: COG1811 Uncharacterized membrane protein possible Na+ channel or pump; InterPro IPR007563; KEGG: brm:Bmur_0947 protein of unknown function DUF554; PFAM: [...]
AEC01470.1 protein networkhttps://string-db.org/network/760011.Spico_0236Gly-Xaa carboxypeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650; KEGG: mxa:MXAN_2289 hypothetical pr [...]
AEC01471.1 protein networkhttps://string-db.org/network/760011.Spico_0237Hypothetical protein; KEGG: cja:CJA_2050 generic methyl-transferase; IMG reference gene:2503956506.
AEC01472.1 protein networkhttps://string-db.org/network/760011.Spico_0238Regulatory protein TetR; InterPro IPR001647; KEGG: cts:Ctha_0156 transcriptional regulator, TetR family; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcrip [...]
AEC01473.1 protein networkhttps://string-db.org/network/760011.Spico_0239Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR000408; KEGG: aeh:Mlg_2687 regulator of chromosome conden [...]
AEC01474.1 protein networkhttps://string-db.org/network/760011.Spico_0240Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural subst [...]
AEC01475.1 protein networkhttps://string-db.org/network/760011.Spico_0241Hypothetical protein; IMG reference gene:2503956510.
AEC01476.1 protein networkhttps://string-db.org/network/760011.Spico_0242KEGG: pan:PODANSg09393 hypothetical protein; IMG reference gene:2503956511.
AEC01477.1 protein networkhttps://string-db.org/network/760011.Spico_0243Transposase IS4 family protein; COGs: COG5421 Transposase; InterPro IPR002559; KEGG: cob:COB47_1677 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family prote [...]
AEC01479.1 protein networkhttps://string-db.org/network/760011.Spico_0246KEGG: bca:BCE_0370 hypothetical protein; SPTR: Cytosine-specific methyltransferase; IMG reference gene:2503956515; PFAM: Helix-turn-helix.
AEC01480.1 protein networkhttps://string-db.org/network/760011.Spico_0247InterPro IPR011639; KEGG: seu:SEQ_0757 modification methylase; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: Putative uncharacterized protein; IMG reference gene:2503956516 [...]
AEC01481.1 protein networkhttps://string-db.org/network/760011.Spico_0248InterPro IPR009528; KEGG: seu:SEQ_0758 type II restriction enzyme; PFAM: Restriction endonuclease, type II, BsuBI/PstI, C-terminal; PRIAM: Type II site-specific deoxyribonuclease; SPTR: Putative [...]
AEC01482.1 protein networkhttps://string-db.org/network/760011.Spico_0249ABC-2 type transporter; InterPro IPR013525; KEGG: tde:TDE0701 hypothetical protein; PFAM: ABC-2 type transporter; SPTR: Membrane protein, putative; IMG reference gene:2503956518; PFAM: ABC-2 type [...]
AEC01483.1 protein networkhttps://string-db.org/network/760011.Spico_0250COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: tde:TDE0702 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Polyam [...]
AEC01484.1 protein networkhttps://string-db.org/network/760011.Spico_0251InterPro IPR006339:IPR007159; KEGG: tde:TDE0703 AbrB family transcriptional regulator; PFAM: Transcription regulator AbrB/SpoV, predicted; SMART: Transcription regulator AbrB/SpoV, predicted; SPT [...]
AEC01485.1 protein networkhttps://string-db.org/network/760011.Spico_0253KEGG: mem:Memar_2263 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956522.
AEC01486.1 protein networkhttps://string-db.org/network/760011.Spico_0254KEGG: ccb:Clocel_1507 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956523.
AEC01487.1 protein networkhttps://string-db.org/network/760011.Spico_0255Domain of unknown function DUF1905; InterPro IPR015018; KEGG: sss:SSUSC84_0626 hypothetical protein; PFAM: Protein of unknown function DUF1905; SPTR: Putative uncharacterized protein; IMG referen [...]
AEC01488.1 protein networkhttps://string-db.org/network/760011.Spico_0256Protein PhnB; COGs: COG2764 conserved hypothetical protein; KEGG: lsp:Bsph_4693 protein PhnB; SPTR: Protein phnB; IMG reference gene:2503956525; PFAM: 3-demethylubiquinone-9 3-methyltransferase.
AEC01489.1 protein networkhttps://string-db.org/network/760011.Spico_0258Transcriptional regulator with cupin sensor, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR013096:IPR000005:IPR018060; KEGG: csh:Closa_3990 transcription [...]
AEC01490.1 protein networkhttps://string-db.org/network/760011.Spico_0259Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: csh:Closa_3984 extracellular solute-binding protein f [...]
AEC01491.1 protein networkhttps://string-db.org/network/760011.Spico_0260Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: csh:Closa_3983 binding-protein-dependen [...]
AEC01492.1 protein networkhttps://string-db.org/network/760011.Spico_0261Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: csh:Closa_3982 binding-protein-dependent [...]
AEC01493.1 protein networkhttps://string-db.org/network/760011.Spico_0262KEGG: cai:Caci_0892 tetratricopeptide TPR_4; SPTR: Putative uncharacterized protein; IMG reference gene:2503956531.
AEC01494.1 protein networkhttps://string-db.org/network/760011.Spico_0263InterPro IPR002575; KEGG: csh:Closa_3988 aminoglycoside phosphotransferase; PFAM: Aminoglycoside phosphotransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2503956532; PFAM: P [...]
AEC01495.1 protein networkhttps://string-db.org/network/760011.Spico_0265KEGG: cpy:Cphy_1854 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956534.
AEC01496.1 protein networkhttps://string-db.org/network/760011.Spico_0266Catalase; COGs: COG0753 Catalase; InterPro IPR018028:IPR010582; KEGG: mla:Mlab_1574 hypothetical protein; PFAM: Catalase-related subgroup; Catalase-related immune responsive; PRIAM: Catalase; SPT [...]
AEC01497.1 protein networkhttps://string-db.org/network/760011.Spico_0267Hypothetical protein; COGs: COG1373 ATPase (AAA+ superfamily); KEGG: swo:Swol_0027 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956536.
AEC01498.1 protein networkhttps://string-db.org/network/760011.Spico_0268COGs: COG0527 Aspartokinase; InterPro IPR001341:IPR001048; KEGG: ssm:Spirs_0574 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; SPTR: Aspartokinase; TIGRFAM: Aspartate kinase domain [...]
AEC01499.1 protein networkhttps://string-db.org/network/760011.Spico_0269Carbohydrate ABC transporter ATP-binding protein, CUT1 family; COGs: COG3839 ABC-type sugar transport systems ATPase components; InterPro IPR003439:IPR013611:IPR003593; KEGG: ssm:Spirs_0579 ABC t [...]
AEC01500.1 protein networkhttps://string-db.org/network/760011.Spico_0270Asparaginase/glutaminase; COGs: COG0252 L-asparaginase/ Glu-tRNAGln amidotransferase subunit D; InterPro IPR006034; KEGG: ade:Adeh_2142 asparaginase; PFAM: Asparaginase/glutaminase; SPTR: Asparag [...]
fhs protein networkhttps://string-db.org/network/760011.Spico_0271Formate-tetrahydrofolate ligase; COGs: COG2759 Formyltetrahydrofolate synthetase; HAMAP: Formate-tetrahydrofolate ligase, FTHFS; InterPro IPR000559; KEGG: dhd:Dhaf_0555 formate--tetrahydrofolate [...]
AEC01502.1 protein networkhttps://string-db.org/network/760011.Spico_0272Extracellular solute-binding protein family 1; COGs: COG1840 ABC-type Fe3+ transport system periplasmic component; InterPro IPR006059; KEGG: kol:Kole_1985 extracellular solute-binding protein fam [...]
AEC01503.1 protein networkhttps://string-db.org/network/760011.Spico_0273COGs: COG1178 ABC-type Fe3+ transport system permease component; InterPro IPR000515; KEGG: kol:Kole_1984 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protei [...]
AEC01504.1 protein networkhttps://string-db.org/network/760011.Spico_0274Polyamine-transporting ATPase; COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003439:IPR013611:IPR003593; KEGG: kol:Kole_1983 ABC transporter relate [...]
AEC01505.1 protein networkhttps://string-db.org/network/760011.Spico_0275Regulatory protein MarR; InterPro IPR000835; KEGG: csh:Closa_1534 transcriptional regulator, MarR family; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SP [...]
AEC01506.1 protein networkhttps://string-db.org/network/760011.Spico_0276FAD dependent oxidoreductase; COGs: COG1233 Phytoene dehydrogenase and related protein; InterPro IPR006076; KEGG: gpb:HDN1F_29420 similar to phytoene dehydrogenase; PFAM: FAD dependent oxidoreduc [...]
AEC01507.1 protein networkhttps://string-db.org/network/760011.Spico_0277Long-chain-fatty-acid--CoA ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: ssm:Spirs_3695 AMP-dependent synthetase and ligase; PFAM: AMP-dependent sy [...]
AEC01508.1 protein networkhttps://string-db.org/network/760011.Spico_0278Hypothetical protein; KEGG: llo:LLO_3092 homologous to SidE substrate of Dot/Icm secretion system; SPTR: Homologous to SidE substrate of Dot/Icm secretion system; IMG reference gene:2503956548.
AEC01509.1 protein networkhttps://string-db.org/network/760011.Spico_0279KEGG: ssm:Spirs_1518 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956549.
AEC01510.1 protein networkhttps://string-db.org/network/760011.Spico_0280Mannose-6-phosphate isomerase, class I; COGs: COG1482 Phosphomannose isomerase; InterPro IPR001250; KEGG: dol:Dole_2015 mannose-6-phosphate isomerase, class I; PFAM: Mannose-6-phosphate isomerase [...]
AEC01511.1 protein networkhttps://string-db.org/network/760011.Spico_0281COGs: COG0847 DNA polymerase III epsilon subunit and related 3'-5' exonuclease; InterPro IPR006054:IPR013520:IPR006055; KEGG: vpr:Vpar_0406 exonuclease RNase T and DNA polymerase III; PFAM: Exonu [...]
AEC01512.1 protein networkhttps://string-db.org/network/760011.Spico_0282InterPro IPR000326; KEGG: ssm:Spirs_0904 phosphoesterase PA-phosphatase related protein; PFAM: Phosphatidic acid phosphatase type 2/haloperoxidase; SMART: Phosphatidic acid phosphatase type 2/hal [...]
mnmA protein networkhttps://string-db.org/network/760011.Spico_0283tRNA-specific 2-thiouridylase mnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
nagB protein networkhttps://string-db.org/network/760011.Spico_0284Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glu [...]
AEC01515.1 protein networkhttps://string-db.org/network/760011.Spico_0285COGs: COG0584 Glycerophosphoryl diester phosphodiesterase; InterPro IPR004129; KEGG: dge:Dgeo_1506 glycerophosphoryl diester phosphodiesterase; PFAM: Glycerophosphoryl diester phosphodiesterase; [...]
AEC01516.1 protein networkhttps://string-db.org/network/760011.Spico_0286tRNA/rRNA methyltransferase (SpoU); COGs: COG0565 rRNA methylase; InterPro IPR001537; KEGG: ssm:Spirs_2304 RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase, SpoU; SP [...]
AEC01517.1 protein networkhttps://string-db.org/network/760011.Spico_0287Protein of unknown function UPF0118; COGs: COG0628 permease; InterPro IPR002549; KEGG: ssm:Spirs_2291 protein of unknown function UPF0118; PFAM: Uncharacterised protein family UPF0118; SPTR: Puta [...]
AEC01518.1 protein networkhttps://string-db.org/network/760011.Spico_0288HhH-GPD family protein; COGs: COG1194 A/G-specific DNA glycosylase; InterPro IPR003265; KEGG: mem:Memar_1721 HhH-GPD family protein; PFAM: HhH-GPD domain; SMART: HhH-GPD domain; SPTR: HhH-GPD fam [...]
AEC01519.1 protein networkhttps://string-db.org/network/760011.Spico_0289Protein of unknown function DUF606; InterPro IPR006750; KEGG: cpy:Cphy_1299 hypothetical protein; PFAM: Protein of unknown function DUF606; SPTR: Putative uncharacterized protein; IMG reference g [...]
AEC01520.1 protein networkhttps://string-db.org/network/760011.Spico_0290Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein; COGs: COG0560 Phosphoserine phosphatase; InterPro IPR011863:IPR005834; KEGG: sta:STHERM_c21790 hypothetical protein; [...]
AEC01521.1 protein networkhttps://string-db.org/network/760011.Spico_0291Transcriptional regulator, TraR/DksA family; COGs: COG1734 DnaK suppressor protein; InterPro IPR000962; KEGG: ssm:Spirs_0464 transcriptional regulator, TraR/DksA family; SPTR: C4 zinc finger doma [...]
AEC01522.1 protein networkhttps://string-db.org/network/760011.Spico_0292Beta-lactamase domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279; KEGG: gka:GK2439 hypothetical protein; PFAM: Beta-lactamase-like; SMART: Beta-lactama [...]
AEC01523.1 protein networkhttps://string-db.org/network/760011.Spico_0293InterPro IPR005580; KEGG: ssm:Spirs_0468 DbpA RNA-binding domain protein; PFAM: DbpA, RNA-binding; SPTR: DbpA RNA binding domain protein; IMG reference gene:2503956564; PFAM: DbpA RNA binding dom [...]
AEC01524.1 protein networkhttps://string-db.org/network/760011.Spico_0294KEGG: ssm:Spirs_0472 hypothetical protein; SPTR: Chromosome assembly protein homolog; IMG reference gene:2503956565.
mltG protein networkhttps://string-db.org/network/760011.Spico_0295Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG fam [...]
AEC01526.1 protein networkhttps://string-db.org/network/760011.Spico_0296COGs: COG3315 O-Methyltransferase involved in polyketide biosynthesis; KEGG: ols:Olsu_0657 tetracenomycin polyketide synthesis O-methyltransferase TcmP; SPTR: Putative uncharacterized protein; IM [...]
AEC01527.1 protein networkhttps://string-db.org/network/760011.Spico_0297Patatin; COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641; KEGG: fjo:Fjoh_0727 patatin; PFAM: Patatin/Phospholipase A2-related; SPTR: Putative patatin-like phosp [...]
queH protein networkhttps://string-db.org/network/760011.Spico_0298Protein of unknown function DUF208; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His [...]
AEC01529.1 protein networkhttps://string-db.org/network/760011.Spico_0299Hypothetical protein; KEGG: ccb:Clocel_0599 TPR repeat-containing protein; SPTR: TPR repeat-containing protein; IMG reference gene:2503956571.
AEC01530.1 protein networkhttps://string-db.org/network/760011.Spico_0300Phospholipase D/Transphosphatidylase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and [...]
AEC01531.1 protein networkhttps://string-db.org/network/760011.Spico_0301Protein of unknown function DUF125 transmembrane; COGs: COG1814 Uncharacterized membrane protein; InterPro IPR008217; KEGG: brm:Bmur_1173 protein of unknown function DUF125 transmembrane; PFAM: D [...]
AEC01532.1 protein networkhttps://string-db.org/network/760011.Spico_0302Trp repressor; InterPro IPR000831; KEGG: sta:STHERM_c18770 hypothetical protein; PFAM: Trp repressor; SPTR: Putative uncharacterized protein; IMG reference gene:2503956574; PFAM: Trp repressor pr [...]
AEC01533.1 protein networkhttps://string-db.org/network/760011.Spico_0303Hypothetical protein; InterPro IPR005242; KEGG: cpy:Cphy_1959 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956575; PFAM: Uncharacterised protein family (UP [...]
AEC01534.1 protein networkhttps://string-db.org/network/760011.Spico_0304COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: bfs:BF3235 putative glycosyl transferase; PFAM: Glycosyl transferase, group 1; SPTR: Putative uncharacterized protein; IMG reference g [...]
AEC01535.1 protein networkhttps://string-db.org/network/760011.Spico_0305DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR011545:IPR001650:IPR014001; KEGG: mba:Mbar_A0145 ATP-dependent RNA helicase; PFAM: DNA/RNA he [...]
AEC01536.1 protein networkhttps://string-db.org/network/760011.Spico_0306KEGG: tde:TDE1337 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956578; PFAM: Protein of unknown function (DUF2804).
AEC01537.1 protein networkhttps://string-db.org/network/760011.Spico_0307InterPro IPR000297; KEGG: ssm:Spirs_1830 PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, PpiC-type; SPTR: Putative uncharacterized protein; IMG reference [...]
AEC01538.1 protein networkhttps://string-db.org/network/760011.Spico_0308KEGG: dhd:Dhaf_0871 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956580.
AEC01539.1 protein networkhttps://string-db.org/network/760011.Spico_0309KEGG: vcn:VOLCADRAFT_103453 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956582.
AEC01540.1 protein networkhttps://string-db.org/network/760011.Spico_0310Extracellular solute-binding protein family 1; COGs: COG1840 ABC-type Fe3+ transport system periplasmic component; InterPro IPR006059; KEGG: aco:Amico_1577 extracellular solute-binding protein fa [...]
AEC01541.1 protein networkhttps://string-db.org/network/760011.Spico_0311COGs: COG1178 ABC-type Fe3+ transport system permease component; InterPro IPR000515; KEGG: aco:Amico_1576 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-prote [...]
AEC01542.1 protein networkhttps://string-db.org/network/760011.Spico_0312Polyamine-transporting ATPase; COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003439:IPR013611:IPR003593; KEGG: csh:Closa_0645 ABC transporter relat [...]
AEC01543.1 protein networkhttps://string-db.org/network/760011.Spico_0313Pectin acetylesterase; COGs: COG0657 Esterase/lipase; KEGG: pjd:Pjdr2_5261 pectin acetylesterase; SPTR: Endo-1,4-beta-xylanase B; IMG reference gene:2503956586; PFAM: Prolyl oligopeptidase family [...]
AEC01544.1 protein networkhttps://string-db.org/network/760011.Spico_0314Hypothetical protein; KEGG: acl:ACL_0438 Fic-domain-containing protein; SPTR: Fic-domain containing protein; IMG reference gene:2503956587.
AEC01545.1 protein networkhttps://string-db.org/network/760011.Spico_0315Amino acid ABC transporter ATP-binding protein, PAAT family; COGs: COG1126 ABC-type polar amino acid transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: ele:Elen_0663 ABC trans [...]
AEC01546.1 protein networkhttps://string-db.org/network/760011.Spico_0316Amino acid ABC transporter membrane protein, PAAT family; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR000515:IPR010065; KEGG: tjr:TherJR_0418 polar amino ac [...]
AEC01547.1 protein networkhttps://string-db.org/network/760011.Spico_0317Amino acid ABC transporter substrate-binding protein, PAAT family; COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638; KEGG: [...]
AEC01548.1 protein networkhttps://string-db.org/network/760011.Spico_0318Sodium ion-translocating decarboxylase, beta subunit; COGs: COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; InterPro IPR005661; KEGG: csh:Closa_2394 sodium ion [...]
AEC01549.1 protein networkhttps://string-db.org/network/760011.Spico_0319Sodium pump decarboxylase gamma subunit; InterPro IPR005899; PFAM: Sodium ion-translocating decarboxylase; SPTR: Putative uncharacterized protein; IMG reference gene:2503956592; PFAM: Oxaloacetat [...]
AEC01550.1 protein networkhttps://string-db.org/network/760011.Spico_0320COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR019455:IPR004789; KEGG: cth:Cthe_2517 acetolactate synthase, small subunit; PFAM: Acetolactate synthase, smal [...]
ilvC protein networkhttps://string-db.org/network/760011.Spico_0321Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yie [...]
leuA protein networkhttps://string-db.org/network/760011.Spico_03222-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isoprop [...]
AEC01553.1 protein networkhttps://string-db.org/network/760011.Spico_03232-isopropylmalate synthase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR013709:IPR005675; KEGG: ccb:Clocel_1321 2-isopropylmalate synthase/homocitrate sy [...]
leuC protein networkhttps://string-db.org/network/760011.Spico_03243-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
leuD protein networkhttps://string-db.org/network/760011.Spico_03253-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. Leu [...]
leuB protein networkhttps://string-db.org/network/760011.Spico_03263-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-met [...]
ilvD protein networkhttps://string-db.org/network/760011.Spico_0327COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; HAMAP: Dihydroxy-acid dehydratase; InterPro IPR004404:IPR000581; KEGG: amt:Amet_3401 dihydroxy-acid dehydratase; PFAM: Dihydr [...]
AEC01558.1 protein networkhttps://string-db.org/network/760011.Spico_0328Acetolactate synthase, large subunit, biosynthetic type; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001:IPR012000:IPR011766:IPR012846; KEGG: cpy:Cphy_3347 acetolactate [...]
AEC01559.1 protein networkhttps://string-db.org/network/760011.Spico_0329Protein of unknown function DUF1538; InterPro IPR011435; KEGG: eel:EUBELI_01841 hypothetical protein; PFAM: Protein of unknown function DUF1538; SPTR: Putative uncharacterized protein; IMG refere [...]
AEC01560.1 protein networkhttps://string-db.org/network/760011.Spico_0330InterPro IPR011701; KEGG: cno:NT01CX_1080 major facilitator superfamily protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily protein; IMG reference gene:2503956 [...]
AEC01561.1 protein networkhttps://string-db.org/network/760011.Spico_0331COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR013200:IPR000150:IPR006379; KEGG: cbe:Cbei_0458 Cof-like hydrolase; PFAM: HAD superfamily hydrolase-like, type 3; SPTR: Cof-like hydrol [...]
AEC01562.1 protein networkhttps://string-db.org/network/760011.Spico_0332Cell wall/surface repeat protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378:IPR011110:IPR000408; KEGG: aeh:Mlg_2687 regulator of chromo [...]
AEC01563.1 protein networkhttps://string-db.org/network/760011.Spico_0333Listeria/Bacterioides repeat-containing protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378:IPR011110:IPR000408; KEGG: aeh:Mlg_2687 regu [...]
AEC01564.1 protein networkhttps://string-db.org/network/760011.Spico_0334Listeria/Bacterioides repeat-containing protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378:IPR000408; KEGG: ttm:Tthe_2617 S-layer domai [...]
AEC01565.1 protein networkhttps://string-db.org/network/760011.Spico_0335Monosaccharide ABC transporter substrate-binding protein, CUT2 family; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: ssm:Spirs_3421 periplasmic bi [...]
AEC01566.1 protein networkhttps://string-db.org/network/760011.Spico_0336Monosaccharide ABC transporter ATP-binding protein, CUT2 family; COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: ssm:Spirs_3420 ABC transporter [...]
AEC01567.1 protein networkhttps://string-db.org/network/760011.Spico_0337Monosaccharide ABC transporter membrane protein, CUT2 family; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: ssm:Spirs [...]
AEC01568.1 protein networkhttps://string-db.org/network/760011.Spico_0338Monosaccharide ABC transporter membrane protein, CUT2 family; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: ssm:Spirs [...]
AEC01569.1 protein networkhttps://string-db.org/network/760011.Spico_0339Carbohydrate kinase, FGGY; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484; KEGG: csh:Closa_0680 ATPase BadF/BadG/BcrA/BcrD type; PFAM: Carbohydrate kinase, FGGY, N-termin [...]
AEC01570.1 protein networkhttps://string-db.org/network/760011.Spico_0340Alpha-N-arabinofuranosidase; COGs: COG3534 Alpha-L-arabinofuranosidase; InterPro IPR010720; KEGG: sta:STHERM_c14770 alpha-N-arabinofuranosidase; PFAM: Alpha-L-arabinofuranosidase, C-terminal; PRI [...]
AEC01571.1 protein networkhttps://string-db.org/network/760011.Spico_0341Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843; KEGG: sta:STHERM_c20570 transcriptional regulatory protein; PFAM: HTH transcriptional regulat [...]
araA protein networkhttps://string-db.org/network/760011.Spico_0342L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose.
AEC01573.1 protein networkhttps://string-db.org/network/760011.Spico_0343COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: cpf:CPF_0648 L-ribulose-5-phosphate 4-epimerase; PFAM: Class II aldolase/adducin, N-te [...]
AEC01574.1 protein networkhttps://string-db.org/network/760011.Spico_0344COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR015590:IPR001670; KEGG: cyj:Cyan7822_1604 iron-containing alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, iron-type; Aldehyde dehydro [...]
AEC01575.1 protein networkhttps://string-db.org/network/760011.Spico_0345Heptaprenyl diphosphate synthase component I; COGs: COG4769 membrane protein; InterPro IPR010898; KEGG: tde:TDE1926 hypothetical protein; PFAM: Heptaprenyl diphosphate synthase component I; SPTR: [...]
AEC01576.1 protein networkhttps://string-db.org/network/760011.Spico_0346Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789 [...]
AEC01577.1 protein networkhttps://string-db.org/network/760011.Spico_0347Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789 [...]
AEC01578.1 protein networkhttps://string-db.org/network/760011.Spico_0348COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: bcv:Bcav_1275 histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase [...]
AEC01579.1 protein networkhttps://string-db.org/network/760011.Spico_0349COGs: COG0469 Pyruvate kinase; InterPro IPR015793:IPR015795:IPR001697; KEGG: cob:COB47_1291 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; PRIAM: Pyruvate kinas [...]
AEC01580.1 protein networkhttps://string-db.org/network/760011.Spico_0350COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR007329:IPR003953:IPR010960; KEGG: ssm:Spirs_3607 flavocytochrome c; PFAM: Fumarate reductase/succinate d [...]
AEC01581.1 protein networkhttps://string-db.org/network/760011.Spico_0351Hypothetical protein; COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; KEGG: dhd:Dhaf_2612 hypothetical protein; SPTR: Putative uncharacterized prote [...]
AEC01582.1 protein networkhttps://string-db.org/network/760011.Spico_0352Binding-protein-dependent transport systems inner membrane component; COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system permease component; InterPro IPR000515; KEGG: dhd:Dhaf_ [...]
AEC01583.1 protein networkhttps://string-db.org/network/760011.Spico_0353Fe(3+)-transporting ATPase; COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: dsa:Desal_1874 ABC transporter related; PFA [...]
AEC01584.1 protein networkhttps://string-db.org/network/760011.Spico_0354Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR001041:IPR019574:IPR001450:IPR004108:IPR 003149:IPR013352; KEGG: cbt:CLH_1644 iron hydrogenas [...]
AEC01585.1 protein networkhttps://string-db.org/network/760011.Spico_0355COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR019575:IPR013027; KEGG: cbt:CLH_1645 putative glutamate synthase (NADPH) small subunit; PFAM: F [...]
AEC01586.1 protein networkhttps://string-db.org/network/760011.Spico_0356Protein of unknown function DUF975; COGs: COG5523 integral membrane protein; InterPro IPR010380; KEGG: clj:CLJU_c32220 hypothetical protein; PFAM: Protein of unknown function DUF975; SPTR: Putati [...]
AEC01588.1 protein networkhttps://string-db.org/network/760011.Spico_0359Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: cob:COB47_1803 transcriptional regulator, AraC family; P [...]
AEC01589.1 protein networkhttps://string-db.org/network/760011.Spico_0360Hypothetical protein; KEGG: caa:Caka_1364 redoxin domain protein; SPTR: Redoxin domain protein; IMG reference gene:2503956633; PFAM: AhpC/TSA family.
AEC01590.1 protein networkhttps://string-db.org/network/760011.Spico_0361Sulfatase; COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: fbc:FB2170_02130 arylsulfatase A precursor; PFAM: Sulfatase; SPTR: Arylsulfatase A; IMG reference gene:2503956634; PFAM: Sulfat [...]
AEC01591.1 protein networkhttps://string-db.org/network/760011.Spico_0362Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_2944 extracellular solute-binding protein [...]
AEC01592.1 protein networkhttps://string-db.org/network/760011.Spico_0363Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_1004 binding-protein-dependent [...]
AEC01593.1 protein networkhttps://string-db.org/network/760011.Spico_0364Binding-protein-dependent transport systems inner membrane component; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_3277 binding- [...]
AEC01594.1 protein networkhttps://string-db.org/network/760011.Spico_0365Glycoside hydrolase family 29 (alpha-L-fucosidase); COGs: COG3669 Alpha-L-fucosidase; InterPro IPR000933; KEGG: tde:TDE0480 alpha-L-fucosidase family protein; PFAM: Glycoside hydrolase, family 29 [...]
AEC01595.1 protein networkhttps://string-db.org/network/760011.Spico_0366Sulfatase; COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: caa:Caka_0229 sulfatase; PFAM: Sulfatase; SPTR: Putative uncharacterized protein; IMG reference gene:2503956639; PFAM: Sulfatas [...]
AEC01596.1 protein networkhttps://string-db.org/network/760011.Spico_0367KEGG: bfo:BRAFLDRAFT_80969 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956641.
AEC01597.1 protein networkhttps://string-db.org/network/760011.Spico_0368Protein of unknown function DUF454; COGs: COG2832 conserved hypothetical protein; InterPro IPR007401; KEGG: hch:HCH_04406 hypothetical protein; PFAM: Protein of unknown function DUF454; SPTR: Unc [...]
AEC01598.1 protein networkhttps://string-db.org/network/760011.Spico_0369Major facilitator superfamily MFS_1; InterPro IPR011701; KEGG: dhd:Dhaf_2526 H+ antiporter protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Putative uncharacterized protein; IMG referenc [...]
AEC01599.1 protein networkhttps://string-db.org/network/760011.Spico_0370InterPro IPR006121; KEGG: mmh:Mmah_1006 heavy metal translocating P-type ATPase; PFAM: Heavy metal transport/detoxification protein; SPTR: Heavy metal transport/detoxification protein; IMG refere [...]
AEC01600.1 protein networkhttps://string-db.org/network/760011.Spico_0371Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006121:IPR008250:IPR005834:IPR006403:IPR 006416:IPR001757; KEGG: brm:Bmur_1532 heavy metal translocating [...]
AEC01601.1 protein networkhttps://string-db.org/network/760011.Spico_0372COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027; KEGG: amt:Amet_0679 putative oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-di [...]
AEC01602.1 protein networkhttps://string-db.org/network/760011.Spico_0373Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: csh:Closa_0691 phosphodiesterase, MJ0936 family; PFAM: Metallo-dependent phosphatase; SPTR: Pu [...]
AEC01603.1 protein networkhttps://string-db.org/network/760011.Spico_0374KEGG: sta:STHERM_c01800 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956648.
AEC01604.1 protein networkhttps://string-db.org/network/760011.Spico_0375COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006097:IPR006096; KEGG: aba:Acid345_0942 glutamate dehydrogenase; PFAM: Glutamate/phenylalanine/leucine/valine dehydrogena [...]
AEC01605.1 protein networkhttps://string-db.org/network/760011.Spico_0376COGs: COG2270 Permease of the major facilitator superfamily; InterPro IPR011701; KEGG: sfu:Sfum_3450 major facilitator transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilita [...]
murB protein networkhttps://string-db.org/network/760011.Spico_0378UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
cysS protein networkhttps://string-db.org/network/760011.Spico_0379COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803; KEGG: sta:STHERM_c18260 hypothetical protein; PFAM: Cysteinyl-tRNA synthetase, class Ia; PRIAM: Cysteine--tRNA ligase; SPTR: Putative [...]
AEC01609.1 protein networkhttps://string-db.org/network/760011.Spico_0380RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627:IPR013249:IPR014284; KEGG: ssm:Spirs_2153 [...]
AEC01610.1 protein networkhttps://string-db.org/network/760011.Spico_0381Hypothetical protein; KEGG: ssm:Spirs_2152 putative transmembrane anti-sigma factor; SPTR: Putative uncharacterized protein; IMG reference gene:2503956656.
AEC01611.1 protein networkhttps://string-db.org/network/760011.Spico_0382Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: pjd:Pjdr2_0473 binding-protein-dependent [...]
AEC01612.1 protein networkhttps://string-db.org/network/760011.Spico_0383Binding-protein-dependent transport systems inner membrane component; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: pjd:Pjdr2_0472 binding-p [...]
AEC01613.1 protein networkhttps://string-db.org/network/760011.Spico_0384Galactosylceramidase; InterPro IPR001286; KEGG: amd:AMED_3993 hypothetical protein; PFAM: Glycoside hydrolase, family 59; PRIAM: Galactosylceramidase; SPTR: Putative uncharacterized protein; IMG [...]
AEC01614.1 protein networkhttps://string-db.org/network/760011.Spico_0385Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: pjd:Pjdr2_0474 extracellular solute-binding protein f [...]
AEC01615.1 protein networkhttps://string-db.org/network/760011.Spico_0386Transcriptional regulator, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR000005:IPR018060; KEGG: ppy:PPE_03254 A [...]
valS protein networkhttps://string-db.org/network/760011.Spico_0387valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
AEC01617.1 protein networkhttps://string-db.org/network/760011.Spico_0388KEGG: pnu:Pnuc_1747 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956663.
AEC01618.1 protein networkhttps://string-db.org/network/760011.Spico_0389Peptidase U32; COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: sta:STHERM_c16410 hypothetical protein; PFAM: Peptidase U32; SPTR: Putative uncharacterized protein; IMG r [...]
lon protein networkhttps://string-db.org/network/760011.Spico_0390ATP dependent PIM1 peptidase; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required f [...]
AEC01620.1 protein networkhttps://string-db.org/network/760011.Spico_0391Protein of unknown function DUF165; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q [...]
AEC01621.1 protein networkhttps://string-db.org/network/760011.Spico_0392Alcohol acetyltransferase; InterPro IPR010828; KEGG: amt:Amet_1520 hypothetical protein; PFAM: Alcohol acetyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2503956667; PF [...]
AEC01622.1 protein networkhttps://string-db.org/network/760011.Spico_0393COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: amt:Amet_1519 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding [...]
AEC01623.1 protein networkhttps://string-db.org/network/760011.Spico_0394Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789 [...]
AEC01624.1 protein networkhttps://string-db.org/network/760011.Spico_0395KEGG: mxa:MXAN_4735 hypothetical protein; SPTR: Putative membrane protein; manually curated; IMG reference gene:2503956670.
recO protein networkhttps://string-db.org/network/760011.Spico_0396DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
AEC01626.1 protein networkhttps://string-db.org/network/760011.Spico_0397single-stranded-DNA-specific exonuclease RecJ; COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR001667:IPR003156:IPR004610; KEGG: ssm:Spirs_2141 single-stranded-DNA-specific ex [...]
rpsU protein networkhttps://string-db.org/network/760011.Spico_0398HAMAP: Ribosomal protein S21; InterPro IPR001911; KEGG: ssm:Spirs_2139 ribosomal protein S21; PFAM: Ribosomal protein S21; SPTR: 30S ribosomal protein S21; TIGRFAM: Ribosomal protein S21; IMG ref [...]
AEC01628.1 protein networkhttps://string-db.org/network/760011.Spico_0399Domain of unknown function DUF1893; InterPro IPR015067; KEGG: amt:Amet_1218 hypothetical protein; PFAM: Protein of unknown function DUF1893; SPTR: Putative uncharacterized protein; IMG reference [...]
AEC01629.1 protein networkhttps://string-db.org/network/760011.Spico_0400Protein of unknown function DUF111; COGs: COG1641 conserved hypothetical protein; InterPro IPR002822; KEGG: mpi:Mpet_1113 hypothetical protein; PFAM: Uncharacterised protein family UPF0272; SPTR: [...]
AEC01630.1 protein networkhttps://string-db.org/network/760011.Spico_0401COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: ssm:Spirs_2138 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: [...]
serC protein networkhttps://string-db.org/network/760011.Spico_0402Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreon [...]
AEC01632.1 protein networkhttps://string-db.org/network/760011.Spico_0403Putative transcriptional regulator, AsnC family; COGs: COG1522 Transcriptional regulators; InterPro IPR019888; KEGG: ssm:Spirs_2136 transcriptional regulator, AsnC family; SMART: Transcription re [...]
AEC01633.1 protein networkhttps://string-db.org/network/760011.Spico_0404Acyltransferase; KEGG: ssm:Spirs_2368 acyltransferase; SPTR: Phospholipid/glycerol acyltransferase; IMG reference gene:2503956679; PFAM: Acyltransferase.
mutL protein networkhttps://string-db.org/network/760011.Spico_0405DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchm [...]
AEC01635.1 protein networkhttps://string-db.org/network/760011.Spico_0406KEGG: nve:NEMVE_v1g200105 hypothetical protein; SPTR: Predicted protein; IMG reference gene:2503956681.
AEC01636.1 protein networkhttps://string-db.org/network/760011.Spico_0407KEGG: ssm:Spirs_2359 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956682.
AEC01637.1 protein networkhttps://string-db.org/network/760011.Spico_0408Metal dependent phosphohydrolase; COGs: COG1078 HD superfamily phosphohydrolase; InterPro IPR003607; KEGG: ssm:Spirs_2352 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase [...]
AEC01638.1 protein networkhttps://string-db.org/network/760011.Spico_0409KEGG: pyo:PY02442 hypothetical protein; SPTR: Zinc finger, C2H2 type, putative; IMG reference gene:2503956685.
AEC01639.1 protein networkhttps://string-db.org/network/760011.Spico_0410Radical SAM domain protein; COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterPro IPR007197:IPR006638; KEGG: ate:Athe_0829 molybdenum cofactor biosynthesis protein A; PFAM: Radical SAM [...]
AEC01640.1 protein networkhttps://string-db.org/network/760011.Spico_0411Radical SAM domain protein; COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterPro IPR007197:IPR006638; KEGG: pab:PAB2273 molybdenum cofactor biosynthesis protein A; PFAM: Radical SAM; [...]
AEC01641.1 protein networkhttps://string-db.org/network/760011.Spico_0412KEGG: dda:Dd703_0966 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956688.
AEC01642.1 protein networkhttps://string-db.org/network/760011.Spico_0413Hypothetical protein; KEGG: dvi:Dvir_GJ17340 GJ17340 gene product from transcript GJ17340-RA; SPTR: GJ17340; IMG reference gene:2503956689.
AEC01643.1 protein networkhttps://string-db.org/network/760011.Spico_0414Methyltransferase type 12; InterPro IPR013217; KEGG: npu:Npun_R0686 methyltransferase type 12; PFAM: Methyltransferase type 12; SPTR: Methyltransferase domain family; IMG reference gene:250395669 [...]
AEC01644.1 protein networkhttps://string-db.org/network/760011.Spico_0415Major facilitator superfamily MFS_1; InterPro IPR011701; KEGG: cbk:CLL_A2467 permease of the major facilitator superfamily; PFAM: Major facilitator superfamily MFS-1; SPTR: Possible MDR-type perm [...]
AEC01645.1 protein networkhttps://string-db.org/network/760011.Spico_0416KEGG: pyo:PY05620 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956692.
AEC01646.1 protein networkhttps://string-db.org/network/760011.Spico_0417KEGG: amr:AM1_1921 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956693.
AEC01647.1 protein networkhttps://string-db.org/network/760011.Spico_0418Abortive infection protein; InterPro IPR003675; KEGG: llk:LLKF_0092 CAAX amino terminal protease family protein; PFAM: Abortive infection protein; SPTR: CAAX amino terminal protease family protei [...]
AEC01648.1 protein networkhttps://string-db.org/network/760011.Spico_0419Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: vdi:Vdis_1894 radical SAM domain-containing protein; PFAM: Radical SAM; SPTR: Putative heme biosynthesis p [...]
valS-2 protein networkhttps://string-db.org/network/760011.Spico_0420valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
AEC01650.1 protein networkhttps://string-db.org/network/760011.Spico_0421COGs: COG5002 Signal transduction histidine kinase; InterPro IPR003660:IPR013767:IPR003661:IPR003594; KEGG: dol:Dole_1931 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, A [...]
AEC01651.1 protein networkhttps://string-db.org/network/760011.Spico_0422Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789 [...]
gpmA protein networkhttps://string-db.org/network/760011.Spico_0424Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
AEC01653.1 protein networkhttps://string-db.org/network/760011.Spico_0425Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR001808; KE [...]
hppA protein networkhttps://string-db.org/network/760011.Spico_0426Inorganic diphosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
AEC01655.1 protein networkhttps://string-db.org/network/760011.Spico_0427Hypothetical protein; KEGG: pmg:P9301_08931 urease subunit alpha; SPTR: Putative uncharacterized protein; IMG reference gene:2503956703.
rpmB protein networkhttps://string-db.org/network/760011.Spico_0428HAMAP: Ribosomal protein L28; InterPro IPR001383; KEGG: ssm:Spirs_2771 ribosomal protein L28; PFAM: Ribosomal protein L28; SPTR: 50S ribosomal protein L28; TIGRFAM: Ribosomal protein L28; IMG ref [...]
AEC01657.1 protein networkhttps://string-db.org/network/760011.Spico_0429COGs: COG0460 Homoserine dehydrogenase; InterPro IPR001048:IPR002912:IPR005106:IPR001342; KEGG: ssm:Spirs_2770 aspartate kinase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine de [...]
AEC01658.1 protein networkhttps://string-db.org/network/760011.Spico_0430COGs: COG0498 Threonine synthase; InterPro IPR001926:IPR004450; KEGG: fph:Fphi_0311 threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Threonine synthase; SPTR: [...]
AEC01659.1 protein networkhttps://string-db.org/network/760011.Spico_0431Galactokinase; COGs: COG0153 Galactokinase; InterPro IPR019539:IPR006204; KEGG: ssm:Spirs_2254 galactokinase; PFAM: Galactokinase galactose-binding domain; GHMP kinase; PRIAM: Galactokinase; SPTR [...]
AEC01660.1 protein networkhttps://string-db.org/network/760011.Spico_0432ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterPro IPR011545:IPR001650:IPR004589:IPR014001; KEGG: ssm:Spirs_2762 ATP-dependent DNA helicase, RecQ family; [...]
AEC01661.1 protein networkhttps://string-db.org/network/760011.Spico_0433COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: mxa:MXAN_3330 1-acyl-sn-glycerol-3-phosphate acyltransferase family protein; PFAM: Phospholipid/glycerol ac [...]
AEC01662.1 protein networkhttps://string-db.org/network/760011.Spico_0434Cell wall/surface repeat protein; InterPro IPR013378; KEGG: geo:Geob_1283 outer membrane adhesin like proteiin; PFAM: Listeria/Bacterioides repeat; SPTR: Outer membrane adhesin like proteiin; TIG [...]
AEC01663.1 protein networkhttps://string-db.org/network/760011.Spico_0435Phosphate binding protein; COGs: COG0226 ABC-type phosphate transport system periplasmic component; InterPro IPR011862; KEGG: ssm:Spirs_1702 phosphate binding protein; SPTR: Phosphate binding pro [...]
AEC01664.1 protein networkhttps://string-db.org/network/760011.Spico_0436Phosphate ABC transporter membrane protein 1, PhoT family; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across [...]
AEC01665.1 protein networkhttps://string-db.org/network/760011.Spico_0437Phosphate ABC transporter, inner membrane subunit PstA; COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR000515:IPR005672; KEGG: ssm:Spirs_1700 phosphate ABC tran [...]
pstB protein networkhttps://string-db.org/network/760011.Spico_0438Phosphate ABC transporter ATP-binding protein, PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belo [...]
AEC01667.1 protein networkhttps://string-db.org/network/760011.Spico_0439Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
AEC01668.1 protein networkhttps://string-db.org/network/760011.Spico_0440Methyltransferase type 11; InterPro IPR013216; KEGG: cbt:CLH_2444 methyltransferase; PFAM: Methyltransferase type 11; SPTR: Methyltransferase; IMG reference gene:2503956716; PFAM: Methyltransfera [...]
AEC01669.1 protein networkhttps://string-db.org/network/760011.Spico_0441Serine palmitoyltransferase; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004839; KEGG: ssm:Spirs_2756 8-amino-7-oxononanoate synthase; PFAM: Aminotransferase, class I/classII; [...]
AEC01670.1 protein networkhttps://string-db.org/network/760011.Spico_0442Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR000408; KEGG: aeh:Mlg_2687 regulator of chromosome conden [...]
AEC01671.1 protein networkhttps://string-db.org/network/760011.Spico_0443COGs: COG1640 4-alpha-glucanotransferase; InterPro IPR003385; KEGG: ssm:Spirs_4115 4-alpha-glucanotransferase; PFAM: Glycoside hydrolase, family 77; PRIAM: 4-alpha-glucanotransferase; SPTR: 4-alp [...]
AEC01672.1 protein networkhttps://string-db.org/network/760011.Spico_0444Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR001761:IPR000843; KEGG: ssm:Spirs_0925 transcriptional regulator, LacI family; PFAM: Periplasmic bind [...]
AEC01673.1 protein networkhttps://string-db.org/network/760011.Spico_0445Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: ccb:Clocel_0515 binding-protein-dependent [...]
AEC01674.1 protein networkhttps://string-db.org/network/760011.Spico_0446Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ccb:Clocel_0514 binding-protein-depende [...]
AEC01675.1 protein networkhttps://string-db.org/network/760011.Spico_0447Carbohydrate ABC transporter substrate-binding protein, CUT1 family; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: ccb:Clocel_0513 extracellular s [...]
AEC01676.1 protein networkhttps://string-db.org/network/760011.Spico_0448COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR001093:IPR000644; KEGG: afn:Acfer_1275 IMP dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; Cystathionine beta-synthase, core; PRIA [...]
AEC01677.1 protein networkhttps://string-db.org/network/760011.Spico_0449Protein of unknown function UPF0001; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
AEC01678.1 protein networkhttps://string-db.org/network/760011.Spico_0450KEGG: ssm:Spirs_2471 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956727.
AEC01679.1 protein networkhttps://string-db.org/network/760011.Spico_0451Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
AEC01680.1 protein networkhttps://string-db.org/network/760011.Spico_0452Beta-lactamase domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279; KEGG: ssm:Spirs_2469 hypothetical protein; PFAM: Beta-lactamase-like; SMART: Beta-lac [...]
AEC01681.1 protein networkhttps://string-db.org/network/760011.Spico_0453Pentapeptide repeat protein; InterPro IPR001646; KEGG: ssm:Spirs_2468 pentapeptide repeat protein; PFAM: Pentapeptide repeat; SPTR: Predicted pentapeptide protein; IMG reference gene:2503956730.
rsgA protein networkhttps://string-db.org/network/760011.Spico_0454Ribosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May [...]
mutS2 protein networkhttps://string-db.org/network/760011.Spico_0455DNA mismatch repair protein MutS domain protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic [...]
AEC01684.1 protein networkhttps://string-db.org/network/760011.Spico_0456Protein of unknown function DUF969; COGs: COG3819 membrane protein; InterPro IPR010374; KEGG: cpe:CPE1427 hypothetical protein; PFAM: Protein of unknown function DUF969; SPTR: Putative uncharacte [...]
AEC01685.1 protein networkhttps://string-db.org/network/760011.Spico_0457Protein of unknown function DUF979; COGs: COG3817 membrane protein; InterPro IPR009323; KEGG: cbt:CLH_1447 permease; PFAM: Protein of unknown function DUF979; SPTR: Permease; IMG reference gene:2 [...]
pcp protein networkhttps://string-db.org/network/760011.Spico_0458Pyroglutamyl-peptidase I; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.
AEC01687.1 protein networkhttps://string-db.org/network/760011.Spico_0459AIG2 family protein; InterPro IPR009288; KEGG: cpe:CPE1424 hypothetical protein; PFAM: AIG2-like; SPTR: Putative uncharacterized protein CPE1424; IMG reference gene:2503956736; PFAM: AIG2-like fa [...]
AEC01688.1 protein networkhttps://string-db.org/network/760011.Spico_0460Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as c [...]
AEC01689.1 protein networkhttps://string-db.org/network/760011.Spico_0461Hypothetical protein; KEGG: nvi:100118784 similar to ENSANGP00000010411; SPTR: Two-component system sensor histidine kinase/response regulator hybrid; IMG reference gene:2503956738.
AEC01690.1 protein networkhttps://string-db.org/network/760011.Spico_0462KEGG: clo:HMPREF0868_0782 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956739.
AEC01691.1 protein networkhttps://string-db.org/network/760011.Spico_0463Flavodoxin; COGs: COG0716 Flavodoxins; InterPro IPR008254:IPR010087; KEGG: emi:Emin_0878 flavodoxin; PFAM: Flavodoxin/nitric oxide synthase; SPTR: Putative uncharacterized protein; TIGRFAM: Flavo [...]
ispG protein networkhttps://string-db.org/network/760011.Spico_04644-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG fa [...]
uvrA protein networkhttps://string-db.org/network/760011.Spico_0465Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of [...]
AEC01694.1 protein networkhttps://string-db.org/network/760011.Spico_0466Hypothetical protein; KEGG: ssm:Spirs_2451 organic solvent tolerance protein OstA; SPTR: Putative uncharacterized protein; IMG reference gene:2503956743.
AEC01695.1 protein networkhttps://string-db.org/network/760011.Spico_0467PhoH family protein; COGs: COG1702 Phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714; KEGG: ssm:Spirs_2450 PhoH family protein; PFAM: PhoH-like protein; SPTR: PhoH- [...]
AEC01696.1 protein networkhttps://string-db.org/network/760011.Spico_0468Metal dependent phosphohydrolase; COGs: COG1480 membrane-associated HD superfamily hydrolase; InterPro IPR006674:IPR006675:IPR003607; KEGG: ssm:Spirs_2449 7TM receptor with intracellular metal de [...]
ybeY protein networkhttps://string-db.org/network/760011.Spico_0469Metalloprotease ybeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
AEC01698.1 protein networkhttps://string-db.org/network/760011.Spico_0470COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR005170; KEGG: ssm:Spirs_2447 transporter-associated region; PFAM: Cystathionine beta-synthase, core; Tra [...]
AEC01699.1 protein networkhttps://string-db.org/network/760011.Spico_0471COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR020828:IPR020829:IPR006424; KEGG: bhr:BH0057 glyceraldehyde 3-phosphate dehydrogenase; PFAM [...]
pgk protein networkhttps://string-db.org/network/760011.Spico_0472COGs: COG0126 3-phosphoglycerate kinase; HAMAP: Phosphoglycerate kinase; InterPro IPR001576; KEGG: ssm:Spirs_2444 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; PRIAM: Phosphoglycerate k [...]
tpiA protein networkhttps://string-db.org/network/760011.Spico_0473Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the [...]
AEC01702.1 protein networkhttps://string-db.org/network/760011.Spico_0474Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
AEC01703.1 protein networkhttps://string-db.org/network/760011.Spico_0475KEGG: bfo:BRAFLDRAFT_98883 hypothetical protein; manually curated; IMG reference gene:2503956752.
AEC01704.1 protein networkhttps://string-db.org/network/760011.Spico_0476KEGG: ssm:Spirs_2441 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956753.
AEC01705.1 protein networkhttps://string-db.org/network/760011.Spico_0477InterPro IPR015391:IPR000297; KEGG: ssm:Spirs_2440 PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, PpiC-type; SurA N-terminal; SPTR: Basic membrane prote [...]
AEC01706.1 protein networkhttps://string-db.org/network/760011.Spico_0478NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the rib [...]
map protein networkhttps://string-db.org/network/760011.Spico_0479Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and [...]
AEC01708.1 protein networkhttps://string-db.org/network/760011.Spico_0480COGs: COG2236 phosphoribosyltransferase; KEGG: ssm:Spirs_2435 phosphoribosyl transferase domain protein; SPTR: Phosphoribosyl transferase domain protein; IMG reference gene:2503956757; PFAM: Phos [...]
AEC01709.1 protein networkhttps://string-db.org/network/760011.Spico_0481Hypothetical protein; KEGG: mxa:MXAN_2109 hyalin repeat-containing protein; SPTR: Hyalin repeat protein; IMG reference gene:2503956758.
AEC01710.1 protein networkhttps://string-db.org/network/760011.Spico_0482KEGG: ssm:Spirs_2430 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956759.
folD protein networkhttps://string-db.org/network/760011.Spico_04835,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydr [...]
AEC01712.1 protein networkhttps://string-db.org/network/760011.Spico_0484tRNA-i(6)A37 thiotransferase enzyme MiaB; COGs: COG0621 2-methylthioadenine synthetase; InterProIPR013848:IPR007197:IPR005839:IPR006463:IPR 006638; KEGG: ssm:Spirs_2426 tRNA-i(6)A37 thiotransfera [...]
AEC01713.1 protein networkhttps://string-db.org/network/760011.Spico_04853-oxoacyl-(acyl-carrier-protein) reductase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: dtu:Dtur_1771 short- [...]
AEC01714.1 protein networkhttps://string-db.org/network/760011.Spico_0486COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; InterPro IPR003000; KEGG: mbu:Mbur_0627 silent informatio [...]
AEC01715.1 protein networkhttps://string-db.org/network/760011.Spico_0487KEGG: vsp:VS_II1427 hypothetical protein; SPTR: Nucleoside recognition domain protein; IMG reference gene:2503956765; PFAM: Nucleoside recognition.
AEC01716.1 protein networkhttps://string-db.org/network/760011.Spico_0488KEGG: dda:Dd703_2631 hypothetical protein; SPTR: Nucleoside recognition domain protein; IMG reference gene:2503956766; PFAM: Nucleoside recognition.
AEC01717.1 protein networkhttps://string-db.org/network/760011.Spico_0489Amidohydrolase; COGs: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR002933:IPR011650:IPR010168; KEGG: tpe:Tpen_1350 amidohydrolase; PFAM: Peptidase M20, dimerisation; [...]
AEC01718.1 protein networkhttps://string-db.org/network/760011.Spico_0490KEGG: cdl:CDR20291_2752 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956768.
AEC01719.1 protein networkhttps://string-db.org/network/760011.Spico_0491KEGG: oih:OB0952 hypothetical protein; SPTR: Putative uncharacterized protein OB0952; IMG reference gene:2503956769.
AEC01720.1 protein networkhttps://string-db.org/network/760011.Spico_0492Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: msv:Mesil_0673 transcriptional regulator, LacI family; PFAM: Periplasmic bind [...]
AEC01721.1 protein networkhttps://string-db.org/network/760011.Spico_0493Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4741 binding-protein-dependent [...]
AEC01722.1 protein networkhttps://string-db.org/network/760011.Spico_0494Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4742 binding-protein- [...]
AEC01723.1 protein networkhttps://string-db.org/network/760011.Spico_0495Type I phosphodiesterase/nucleotide pyrophosphatase; COGs: COG1524 Uncharacterized protein of the AP superfamily; InterPro IPR002591; KEGG: bcv:Bcav_2459 type I phosphodiesterase/nucleotide pyrop [...]
AEC01724.1 protein networkhttps://string-db.org/network/760011.Spico_0496PHP domain protein; COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR004013:IPR003141; KEGG: tko:TK0327 hypothetical protein; PFAM: PHP, C-terminal; SMART [...]
AEC01725.1 protein networkhttps://string-db.org/network/760011.Spico_0497Sucrose phosphorylase; COGs: COG0366 Glycosidase; InterPro IPR006047:IPR006589; KEGG: sta:STHERM_c12800 hypothetical protein; PFAM: Glycosyl hydrolase, family 13, catalytic domain; PRIAM: Sucrose [...]
AEC01726.1 protein networkhttps://string-db.org/network/760011.Spico_0498KEGG: rrs:RoseRS_2835 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956776; PFAM: Protein of unknown function (DUF2961).
AEC01727.1 protein networkhttps://string-db.org/network/760011.Spico_0499Beta-lactamase domain protein; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR001279; KEGG: ppd:Ppro_1379 DNA internalization-related competence protein ComEC/Rec2; PFA [...]
AEC01728.1 protein networkhttps://string-db.org/network/760011.Spico_0500Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_0760 extracellular solute-binding protein [...]
AEC01729.1 protein networkhttps://string-db.org/network/760011.Spico_0501Transcriptional regulator, GntR family; COGs: COG1802 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: ssm:Spirs_0802 transcriptional regulator, GntR family; PFAM: HTH transcriptio [...]
metE protein networkhttps://string-db.org/network/760011.Spico_0502Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 indepe [...]
AEC01731.1 protein networkhttps://string-db.org/network/760011.Spico_0503COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171:IPR004620; KEGG: swo:Swol_0934 5,10-methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; PRIA [...]
AEC01732.1 protein networkhttps://string-db.org/network/760011.Spico_0504Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: swo:Swol_0935 LysR-type transcriptional regulator; PFAM: HTH transcriptional r [...]
AEC01733.1 protein networkhttps://string-db.org/network/760011.Spico_0505KEGG: bhy:BHWA1_00761 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956783.
AEC01734.1 protein networkhttps://string-db.org/network/760011.Spico_0506InterPro IPR006628; KEGG: ssm:Spirs_1866 PUR-alpha/beta/gamma DNA/RNA-binding protein; SMART: PUR-alpha/beta/gamma, DNA/RNA-binding; SPTR: Putative uncharacterized protein; IMG reference gene:250 [...]
rnhB protein networkhttps://string-db.org/network/760011.Spico_0507Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
smc protein networkhttps://string-db.org/network/760011.Spico_0508SMC domain protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
ffh protein networkhttps://string-db.org/network/760011.Spico_0509Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of [...]
rpsP protein networkhttps://string-db.org/network/760011.Spico_0510COGs: COG0228 Ribosomal protein S16; HAMAP: Ribosomal protein S16; InterPro IPR000307; KEGG: ssm:Spirs_1872 ribosomal protein S16; PFAM: Ribosomal protein S16; SPTR: 30S ribosomal protein S16; TI [...]
AEC01739.1 protein networkhttps://string-db.org/network/760011.Spico_0511COGs: COG1837 RNA-binding protein (contains KH domain); HAMAP: Uncharacterised protein family UPF0109, bacterial; InterPro IPR020627; KEGG: ssm:Spirs_1873 R-binding protein (contains KH domain); [...]
rimM protein networkhttps://string-db.org/network/760011.Spico_0512Ribosome maturation factor rimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. [...]
trmD protein networkhttps://string-db.org/network/760011.Spico_0513tRNA (Guanine37-N(1)-) methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rplS protein networkhttps://string-db.org/network/760011.Spico_0514LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
AEC01743.1 protein networkhttps://string-db.org/network/760011.Spico_0515UPF0102 protein yraN; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; HAMAP: Uncharacterised protein family UPF0102; InterPro IPR003509; KEGG: cyh:Cyan8802_3919 prote [...]
AEC01744.1 protein networkhttps://string-db.org/network/760011.Spico_0516KEGG: tde:TDE2305 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956794.
coaD protein networkhttps://string-db.org/network/760011.Spico_0517Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD [...]
rpmF protein networkhttps://string-db.org/network/760011.Spico_0518COGs: COG0333 Ribosomal protein L32; HAMAP: Ribosomal protein L32p; InterPro IPR002677; KEGG: ssm:Spirs_1887 ribosomal protein L32; PFAM: Ribosomal protein L32p; SPTR: 50S ribosomal protein L32; [...]
acpP protein networkhttps://string-db.org/network/760011.Spico_0519Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
rnc protein networkhttps://string-db.org/network/760011.Spico_0520RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, a [...]
AEC01749.1 protein networkhttps://string-db.org/network/760011.Spico_0521Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674:IPR006675; KEGG: ssm:Spirs_1890 pol [...]
ileS protein networkhttps://string-db.org/network/760011.Spico_0522Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
AEC01751.1 protein networkhttps://string-db.org/network/760011.Spico_0523Hypothetical protein; KEGG: tbd:Tbd_1366 diguanylate cyclase/phosphodiesterase; SPTR: Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(S); IMG reference ge [...]
thiI protein networkhttps://string-db.org/network/760011.Spico_0524tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the tran [...]
AEC01753.1 protein networkhttps://string-db.org/network/760011.Spico_0525COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192; KEGG: sta:STHERM_c15870 putative cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase; [...]
AEC01754.1 protein networkhttps://string-db.org/network/760011.Spico_0526COGs: COG0337 3-dehydroquinate synthetase; InterPro IPR002658; KEGG: ssm:Spirs_1902 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase AroB; PRIAM: 3-dehydroquinate synthase; SPTR: 3-dehy [...]
AEC01755.1 protein networkhttps://string-db.org/network/760011.Spico_0527Protein of unknown function DUF1605; COGs: COG1643 HrpA-like helicase; InterPro IPR001650:IPR007502:IPR011709:IPR014001; KEGG: ssm:Spirs_1903 protein of unknown function DUF1605; PFAM: Domain of [...]
hisS protein networkhttps://string-db.org/network/760011.Spico_0528COGs: COG0124 Histidyl-tRNA synthetase; HAMAP: Histidyl-tRNA synthetase, class IIa, subgroup; InterPro IPR015807:IPR002314:IPR004154; KEGG: ssm:Spirs_1904 histidyl-tRNA synthetase; PFAM: Aminoacy [...]
AEC01757.1 protein networkhttps://string-db.org/network/760011.Spico_0529poly(A) polymerase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR010206; KEGG: ssm:Spirs_1905 poly(A) polymerase; PFAM: Poly A polymerase, head domain; PRIA [...]
AEC01758.1 protein networkhttps://string-db.org/network/760011.Spico_0530KEGG: ssm:Spirs_1907 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956808.
rnfC protein networkhttps://string-db.org/network/760011.Spico_0531Electron transport complex, RnfABCDGE type, C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacteri [...]
rnfD protein networkhttps://string-db.org/network/760011.Spico_0532Electron transport complex, RnfABCDGE type, D subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD fam [...]
AEC01761.1 protein networkhttps://string-db.org/network/760011.Spico_0533FMN-binding domain protein; InterPro IPR007329; KEGG: ssm:Spirs_1911 FMN-binding domain protein; PFAM: FMN-binding; SMART: FMN-binding; SPTR: Electron transport complex, rnfabcdGe type, g subunit [...]
AEC01762.1 protein networkhttps://string-db.org/network/760011.Spico_0534RnfA-Nqr electron transport subunit; COGs: COG4660 NADH:ubiquinone oxidoreductase subunit RnfE; InterPro IPR003667; KEGG: ssm:Spirs_1912 electron transport complex, RnfABCDGE type, E subunit; PFA [...]
AEC01763.1 protein networkhttps://string-db.org/network/760011.Spico_0535COGs: COG4657 NADH:ubiquinone oxidoreductase subunit RnfA; KEGG: ssm:Spirs_1913 electron transport complex, RnfABCDGE type, A subunit; SPTR: Na(+)-translocating NADH-quinone reductase subunit E; [...]
AEC01764.1 protein networkhttps://string-db.org/network/760011.Spico_0536Glycoside hydrolase family 57; InterPro IPR004300:IPR015179; KEGG: ssm:Spirs_1915 4-alpha-glucanotransferase; PFAM: Glycoside hydrolase, family 57, N-terminal; Alpha-amylase/4-alpha-glucanotransf [...]
prfB protein networkhttps://string-db.org/network/760011.Spico_0537Bacterial peptide chain release factor 2 (bRF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
AEC01766.1 protein networkhttps://string-db.org/network/760011.Spico_0538Hypothetical protein; KEGG: mhu:Mhun_2300 PEGA; SPTR: PEGA; IMG reference gene:2503956816.
ftsY protein networkhttps://string-db.org/network/760011.Spico_0539Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the [...]
AEC01768.1 protein networkhttps://string-db.org/network/760011.Spico_0540Protein of unknown function DUF214; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: sta:STHERM_c12430 putative lipoprotein re [...]
AEC01769.1 protein networkhttps://string-db.org/network/760011.Spico_0541Phosphonate-transporting ATPase; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c12420 lipoprotein-releasing system [...]
AEC01770.1 protein networkhttps://string-db.org/network/760011.Spico_0542Protein of unknown function DUF214; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: ssm:Spirs_1925 protein of unknown functio [...]
rnz protein networkhttps://string-db.org/network/760011.Spico_0543RNAse Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the [...]
AEC01772.1 protein networkhttps://string-db.org/network/760011.Spico_0544KEGG: mdi:METDI2989 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956822.
AEC01773.1 protein networkhttps://string-db.org/network/760011.Spico_0545Septum formation initiator; InterPro IPR007060; KEGG: pay:PAU_00273 hypothetical protein; PFAM: Septum formation initiator; SPTR: Putative uncharacterized protein; IMG reference gene:2503956823.
AEC01774.1 protein networkhttps://string-db.org/network/760011.Spico_0546SUA5/yciO/yrdC domain protein; COGs: COG0009 Putative translation factor (SUA5); InterPro IPR006070; KEGG: ssm:Spirs_1938 SUA5/YciO/YrdC/YwlC family protein; PFAM: Sua5/YciO/YrdC, N-terminal; SPT [...]
AEC01775.1 protein networkhttps://string-db.org/network/760011.Spico_0547Uncharacterized conserved protein UCP033563; InterPro IPR008323; KEGG: ssm:Spirs_1939 hypothetical protein; PFAM: Uncharacterised conserved protein UCP033563; SPTR: Putative uncharacterized prote [...]
AEC01776.1 protein networkhttps://string-db.org/network/760011.Spico_0548COGs: COG1564 Thiamine pyrophosphokinase; InterPro IPR007371:IPR006282; KEGG: ssm:Spirs_1940 thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase, catalytic domain; SPTR: Putative uncharac [...]
AEC01777.1 protein networkhttps://string-db.org/network/760011.Spico_0549Hypothetical protein; KEGG: cff:CFF8240_1387 polysaccharide biosynthesis protein; SPTR: Polysaccharide biosynthesis protein; IMG reference gene:2503956827.
AEC01778.1 protein networkhttps://string-db.org/network/760011.Spico_0550COGs: COG4401 Chorismate mutase; InterPro IPR008243; KEGG: chy:CHY_0473 chorismate mutase; PFAM: Chorismate mutase, AroH class; SPTR: Chorismate mutase; TIGRFAM: Chorismate mutase, AroH class; IM [...]
AEC01779.1 protein networkhttps://string-db.org/network/760011.Spico_0551Hypothetical protein; KEGG: fbl:Fbal_1981 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD; SPTR: Transport ATP-binding protein aarD; IMG reference gen [...]
AEC01780.1 protein networkhttps://string-db.org/network/760011.Spico_0552COGs: COG0338 Site-specific DNA methylase; InterPro IPR012327; KEGG: lba:Lebu_2246 DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; SPTR: DNA adenine methylase; T [...]
AEC01781.1 protein networkhttps://string-db.org/network/760011.Spico_0553Type II site-specific deoxyribonuclease; Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1; Belongs to the type II restriction enzyme DpnII family.
AEC01782.1 protein networkhttps://string-db.org/network/760011.Spico_0554DNA methylase N-4/N-6 domain protein; COGs: COG1041 DNA modification methylase; InterPro IPR002941; KEGG: lba:Lebu_2245 putative RNA methylase; PFAM: DNA methylase N-4/N-6; SPTR: DNA methylase N- [...]
AEC01784.1 protein networkhttps://string-db.org/network/760011.Spico_0556Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: str:Sterm_1975 transcriptional regulator, LysR family; PFAM: HTH transcription [...]
AEC01785.1 protein networkhttps://string-db.org/network/760011.Spico_0557COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR023210; KEGG: ssm:Spirs_1777 aldo/keto reductase; PFAM: NADP-dependent oxidoreductase domain; PRIAM: 2,5-didehyd [...]
AEC01786.1 protein networkhttps://string-db.org/network/760011.Spico_0558KEGG: shi:Shel_18140 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956837.
AEC01787.1 protein networkhttps://string-db.org/network/760011.Spico_0559Maltose O-acetyltransferase; COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR001451; KEGG: cgr:CAGL0K11066g hypothetical protein; PRIAM: Maltose O-acetyltransferase; S [...]
AEC01788.1 protein networkhttps://string-db.org/network/760011.Spico_0560NADPH-dependent FMN reductase; COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: brm:Bmur_2381 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: Putative [...]
AEC01789.1 protein networkhttps://string-db.org/network/760011.Spico_0561Regulatory protein TetR; InterPro IPR001647; KEGG: cpy:Cphy_1864 TetR family transcriptional regulator; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcript [...]
AEC01790.1 protein networkhttps://string-db.org/network/760011.Spico_0562FMN-binding domain protein; COGs: COG3976 conserved hypothetical protein; InterPro IPR007329; KEGG: cbe:Cbei_3767 FMN-binding domain-containing protein; PFAM: FMN-binding; SMART: FMN-binding; SPT [...]
AEC01791.1 protein networkhttps://string-db.org/network/760011.Spico_0563KEGG: str:Sterm_3493 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956842.
AEC01792.1 protein networkhttps://string-db.org/network/760011.Spico_0564Hypothetical protein; KEGG: lcz:LCAZH_2061 sucrose PTS, EIIBCA; SPTR: Putative uncharacterized protein; IMG reference gene:2503956843.
AEC01793.1 protein networkhttps://string-db.org/network/760011.Spico_0565ABC transporter related protein; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: btl:BALH_2607 ABC transporter, ATP-binding protein; PFAM: [...]
AEC01794.1 protein networkhttps://string-db.org/network/760011.Spico_0566Hypothetical protein; KEGG: bth:BT_4430 cytochrome c biogenesis protein (CcsA); SPTR: Permease; IMG reference gene:2503956845.
AEC01795.1 protein networkhttps://string-db.org/network/760011.Spico_0567Protein of unknown function DUF2174; COGs: COG4832 conserved hypothetical protein; InterPro IPR019233; KEGG: mla:Mlab_0505 hypothetical protein; PFAM: Protein of unknown function DUF2174, N-termi [...]
AEC01796.1 protein networkhttps://string-db.org/network/760011.Spico_0568Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein; COGs: COG3871 Uncharacterized stress protein (general stress protein 26); InterPro IPR011576; KEGG: bth:BT_1384 hypothetical protein [...]
AEC01797.1 protein networkhttps://string-db.org/network/760011.Spico_0569COGs: COG4898 conserved hypothetical protein; InterPro IPR014580; KEGG: dae:Dtox_0463 hypothetical protein; PFAM: Uncharacterised conserved protein UCP033199; SPTR: Putative uncharacterized prote [...]
AEC01799.1 protein networkhttps://string-db.org/network/760011.Spico_0571Nitroreductase; KEGG: ols:Olsu_1506 nitroreductase; SPTR: Putative uncharacterized protein; IMG reference gene:2503956850.
AEC01800.1 protein networkhttps://string-db.org/network/760011.Spico_0572Glutamate synthase (NADH) small subunit; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR006005; KEGG: pdi:BDI_0325 glutamate synthas [...]
AEC01801.1 protein networkhttps://string-db.org/network/760011.Spico_0573Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: pdi:BDI_0326 glutamate synthase, large subunit; PFAM: G [...]
AEC01802.1 protein networkhttps://string-db.org/network/760011.Spico_0574Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: dsy:DSY4193 hypothetical protein; PFAM: Transcription regulator Rrf2; SPTR: [...]
AEC01803.1 protein networkhttps://string-db.org/network/760011.Spico_0575Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: cce:Ccel_1933 transcriptional regulator, BadM/Rrf2 family; PFAM: Transcript [...]
AEC01804.1 protein networkhttps://string-db.org/network/760011.Spico_0576Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198; KEGG: cak:Caul_2944 short-chain dehydrogenase/reductase SD [...]
AEC01805.1 protein networkhttps://string-db.org/network/760011.Spico_0577Integrase family protein; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: ssm:Spirs_2778 integrase family protein; PFAM: Integrase, catalytic core, phage; SPTR: Lj965 prop [...]
smpB protein networkhttps://string-db.org/network/760011.Spico_0578SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tm [...]
AEC01807.1 protein networkhttps://string-db.org/network/760011.Spico_0579Sulphatase-modifying factor protein; COGs: COG1262 conserved hypothetical protein; InterPro IPR005532; KEGG: ssm:Spirs_2010 protein of unknown function DUF323; PFAM: Sulphatase-modifying factor; [...]
AEC01808.1 protein networkhttps://string-db.org/network/760011.Spico_0580Signal peptidase I; InterPro IPR019759:IPR000223; KEGG: ssm:Spirs_2011 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; SPTR: Signal peptidase I; TIGRFAM: Peptidase S26A, sign [...]
AEC01809.1 protein networkhttps://string-db.org/network/760011.Spico_0581COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR007197:IPR010723:IPR004559:IPR006638; KEGG: dba:Dbac_3351 oxygen-independent coproporphyrinogen III oxida [...]
AEC01810.1 protein networkhttps://string-db.org/network/760011.Spico_0582UPF0082 protein yeeN; COGs: COG0217 conserved hypothetical protein; HAMAP: Protein of unknown function DUF28; InterPro IPR002876; KEGG: ssm:Spirs_2014 protein of unknown function DUF28; PFAM: Pro [...]
ruvC protein networkhttps://string-db.org/network/760011.Spico_0583Crossover junction endodeoxyribonuclease ruvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to st [...]
ruvA protein networkhttps://string-db.org/network/760011.Spico_0584Holliday junction ATP-dependent DNA helicase ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may [...]
ruvB protein networkhttps://string-db.org/network/760011.Spico_0585Holliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promot [...]
queA protein networkhttps://string-db.org/network/760011.Spico_0586S-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (o [...]
tmk protein networkhttps://string-db.org/network/760011.Spico_0587Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
AEC01816.1 protein networkhttps://string-db.org/network/760011.Spico_0588InterPro IPR007452; KEGG: ssm:Spirs_2021 protein of unknown function DUF490; PFAM: Protein of unknown function DUF490; SPTR: Putative uncharacterized protein; IMG reference gene:2503956867; PFAM: [...]
AEC01817.1 protein networkhttps://string-db.org/network/760011.Spico_0589COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184:IPR016474; KEGG: ssm:Spirs_2022 outer membrane protein assembly complex, YaeT protein; PFAM: Bacterial [...]
mutS protein networkhttps://string-db.org/network/760011.Spico_0590DNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase act [...]
AEC01819.1 protein networkhttps://string-db.org/network/760011.Spico_0591Hypothetical protein; COGs: COG1040 amidophosphoribosyltransferase; KEGG: ele:Elen_1211 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956870.
rimP protein networkhttps://string-db.org/network/760011.Spico_0592Ribosome maturation factor rimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
nusA protein networkhttps://string-db.org/network/760011.Spico_0593NusA antitermination factor; Participates in both transcription termination and antitermination.
infB protein networkhttps://string-db.org/network/760011.Spico_0594Bacterial translation initiation factor 2 (bIF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes [...]
rbfA protein networkhttps://string-db.org/network/760011.Spico_0595Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
truB protein networkhttps://string-db.org/network/760011.Spico_0596tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
AEC01825.1 protein networkhttps://string-db.org/network/760011.Spico_0597COGs: COG0196 FAD synthase; InterPro IPR015864; KEGG: sta:STHERM_c11150 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; SPTR: Riboflavin biosynthesis protein RibF; IMG reference gene: [...]
rpsO protein networkhttps://string-db.org/network/760011.Spico_0598SSU ribosomal protein S15P; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
pnp protein networkhttps://string-db.org/network/760011.Spico_0599Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
dut protein networkhttps://string-db.org/network/760011.Spico_0600Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intrace [...]
AEC01829.1 protein networkhttps://string-db.org/network/760011.Spico_0601Permease YjgP/YjgQ family protein; COGs: COG0795 permease; InterPro IPR005495; KEGG: sta:STHERM_c11120 hypothetical protein; PFAM: Permease YjgP/YjgQ, predicted; SPTR: Putative uncharacterized pr [...]
AEC01830.1 protein networkhttps://string-db.org/network/760011.Spico_0602Permease YjgP/YjgQ family protein; COGs: COG0795 permease; InterPro IPR005495; KEGG: sta:STHERM_c11110 permease YjgP/YjgQ family protein; PFAM: Permease YjgP/YjgQ, predicted; SPTR: Permease YjgP/ [...]
tgt protein networkhttps://string-db.org/network/760011.Spico_0603tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in t [...]
AEC01832.1 protein networkhttps://string-db.org/network/760011.Spico_0604Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
greA protein networkhttps://string-db.org/network/760011.Spico_0605Transcription elongation factor, GreA/GreB, N-terminal protein; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA h [...]
AEC01834.1 protein networkhttps://string-db.org/network/760011.Spico_0606COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: tde:TDE2597 ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; S [...]
dtd protein networkhttps://string-db.org/network/760011.Spico_0607D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischar [...]
recA protein networkhttps://string-db.org/network/760011.Spico_0608RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of hom [...]
AEC01837.1 protein networkhttps://string-db.org/network/760011.Spico_0609Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB tha [...]
AEC01838.1 protein networkhttps://string-db.org/network/760011.Spico_0610Chromosome segregation and condensation protein, ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA th [...]
AEC01839.1 protein networkhttps://string-db.org/network/760011.Spico_0611Pseudouridine synthase Rsu; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR002942:IPR006145:IPR000748; KEGG: ssm:Spirs_2054 RNA-bind [...]
cmk protein networkhttps://string-db.org/network/760011.Spico_0612COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR003136:IPR011994; KEGG: ssm:Spirs_2055 cytidylate kinase; PFAM: Cytidylate kinase domain; SPTR: Cytidylate kinase; TIGRFAM: [...]
AEC01841.1 protein networkhttps://string-db.org/network/760011.Spico_0613RNA binding S1 domain protein; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
AEC01842.1 protein networkhttps://string-db.org/network/760011.Spico_0614InterPro IPR013105; KEGG: sta:STHERM_c10950 hypothetical protein; PFAM: Tetratricopeptide TPR2; SPTR: Putative uncharacterized protein; IMG reference gene:2503956893.
AEC01843.1 protein networkhttps://string-db.org/network/760011.Spico_0615Hypothetical protein; KEGG: tgu:100222319 similar to von Willebrand factor; SPTR: ATP-dependent zinc metalloprotease FtsH homolog; IMG reference gene:2503956894.
AEC01844.1 protein networkhttps://string-db.org/network/760011.Spico_0616MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518:IPR011551; KEGG: ssm:Spirs_2069 Ma [...]
AEC01845.1 protein networkhttps://string-db.org/network/760011.Spico_0617Protein of unknown function DUF164; COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: ssm:Spirs_2077 protein of unknown function DUF164; PFAM: Protein of un [...]
rpoD protein networkhttps://string-db.org/network/760011.Spico_0618RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is [...]
dnaG protein networkhttps://string-db.org/network/760011.Spico_0619DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
AEC01848.1 protein networkhttps://string-db.org/network/760011.Spico_0620Protein of unknown function UPF0153; InterPro IPR005358; KEGG: sta:STHERM_c10760 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: Putative uncharacterized protein; IMG re [...]
AEC01849.1 protein networkhttps://string-db.org/network/760011.Spico_0621COGs: COG2309 Leucyl aminopeptidase (aminopeptidase T); InterPro IPR000787; KEGG: lsp:Bsph_0293 aminopeptidase AmpS; PFAM: Peptidase M29, aminopeptidase II; SPTR: Aminopeptidase ampS; IMG referen [...]
AEC01850.1 protein networkhttps://string-db.org/network/760011.Spico_0622COGs: COG2309 Leucyl aminopeptidase (aminopeptidase T); InterPro IPR000787; KEGG: baf:BAPKO_0070 aminopeptidase II; PFAM: Peptidase M29, aminopeptidase II; SPTR: Aminopeptidase II; IMG reference [...]
coaX protein networkhttps://string-db.org/network/760011.Spico_0623Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
AEC01852.1 protein networkhttps://string-db.org/network/760011.Spico_0624COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439:IPR003593; KEGG: ssm:Spirs_1718 ABC transporter related protein; PFAM: ABC transporter-like; [...]
apt protein networkhttps://string-db.org/network/760011.Spico_0625Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
tsaD protein networkhttps://string-db.org/network/760011.Spico_0626O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in t [...]
AEC01855.1 protein networkhttps://string-db.org/network/760011.Spico_0627Hypothetical protein; IMG reference gene:2503956910.
AEC01856.1 protein networkhttps://string-db.org/network/760011.Spico_0628Pyruvate phosphate dikinase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192:IPR008279:IPR000121:IPR010121; KEGG: rmr:Rmar_0942 pyruvate, phosphate diki [...]
AEC01857.1 protein networkhttps://string-db.org/network/760011.Spico_0629RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
AEC01858.1 protein networkhttps://string-db.org/network/760011.Spico_0630KEGG: ncr:NCU05178 hypothetical protein; SPTR: 3-deoxy-D-manno-octulosonic-acid transferase; IMG reference gene:2503956914.
groS protein networkhttps://string-db.org/network/760011.Spico_063110 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
AEC01860.1 protein networkhttps://string-db.org/network/760011.Spico_0632Helicase c2; COGs: COG1199 Rad3-related DNA helicase; InterPro IPR006555; KEGG: ssm:Spirs_1712 helicase C2; SMART: Helicase, ATP-dependent, c2 type; SPTR: Putative uncharacterized protein; IMG re [...]
AEC01861.1 protein networkhttps://string-db.org/network/760011.Spico_0633Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789: [...]
AEC01862.1 protein networkhttps://string-db.org/network/760011.Spico_0634Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: ssm:Spirs_1708 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, AT [...]
AEC01863.1 protein networkhttps://string-db.org/network/760011.Spico_0635Hypothetical protein; COGs: COG2812 DNA polymerase III gamma/tau subunits; KEGG: ssm:Spirs_1707 DNA polymerase III gamma/tau subunits; SPTR: DNA polymerase III domain protein; IMG reference gene: [...]
AEC01864.1 protein networkhttps://string-db.org/network/760011.Spico_0636KEGG: ppy:PPE_00816 adenine specific DNA methylase Mod; SPTR: Putative uncharacterized protein; IMG reference gene:2503956920.
AEC01865.1 protein networkhttps://string-db.org/network/760011.Spico_0637Colicin V production protein; InterPro IPR003825; KEGG: tde:TDE1973 CvpA family protein; PFAM: Colicin V production, CvpA; SPTR: CvpA family protein; IMG reference gene:2503956921; PFAM: Colicin [...]
murG protein networkhttps://string-db.org/network/760011.Spico_0638Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid interme [...]
secA protein networkhttps://string-db.org/network/760011.Spico_0639Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the [...]
AEC01868.1 protein networkhttps://string-db.org/network/760011.Spico_0640Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR018392:IPR016047:IPR002482; KEGG: bpo:BP951000_1905 LysM domain/M23/M37 peptidase domain-containing prot [...]
AEC01869.1 protein networkhttps://string-db.org/network/760011.Spico_0641Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR001460; KEGG: ssm:Spirs_2628 peptidoglycan glycosyltransferase; PFAM: Penicil [...]
AEC01870.1 protein networkhttps://string-db.org/network/760011.Spico_0642GTP-binding signal recognition particle SRP54 G- domain protein; COGs: COG1419 Flagellar GTP-binding protein; InterPro IPR000897:IPR003593; KEGG: ssm:Spirs_1583 flagellar biosynthetic protein Flh [...]
AEC01871.1 protein networkhttps://string-db.org/network/760011.Spico_0643Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.
hslV protein networkhttps://string-db.org/network/760011.Spico_0644ATP-dependent protease hslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
AEC01873.1 protein networkhttps://string-db.org/network/760011.Spico_0645Tyrosine recombinase xerC; COGs: COG4974 Site-specific recombinase XerD; HAMAP: Tyrosine recombinase xerC; InterPro IPR004107:IPR002104; KEGG: toc:Toce_1087 tyrosine recombinase XerC; PFAM: Integ [...]
AEC01874.1 protein networkhttps://string-db.org/network/760011.Spico_0646Hypothetical protein; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; KEGG: sta:STHERM_c09020 putative DNA processing protein DprA; SPTR: Smf protein; IMG reference [...]
xerC protein networkhttps://string-db.org/network/760011.Spico_0647Tyrosine recombinase xerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert [...]
ftsZ protein networkhttps://string-db.org/network/760011.Spico_0648Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the tim [...]
ftsA protein networkhttps://string-db.org/network/760011.Spico_0649Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
AEC01878.1 protein networkhttps://string-db.org/network/760011.Spico_0650Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
AEC01879.1 protein networkhttps://string-db.org/network/760011.Spico_0651Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: sta:STHERM_c08960 hypothetical protein; PFAM: Cell cycle protein; SPTR: Putative uncharacteri [...]
mraY protein networkhttps://string-db.org/network/760011.Spico_0652Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY s [...]
AEC01881.1 protein networkhttps://string-db.org/network/760011.Spico_0653UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptid [...]
AEC01882.1 protein networkhttps://string-db.org/network/760011.Spico_0654Hypothetical protein; KEGG: cdi:DIP2252 putative integral membrane protein; SPTR: Putative conserved integral membrane protein; IMG reference gene:2503956938; TIGRFAM: cell division protein FtsL.
rsmH protein networkhttps://string-db.org/network/760011.Spico_0655Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
mraZ protein networkhttps://string-db.org/network/760011.Spico_0656Protein mraZ; COGs: COG2001 conserved hypothetical protein; HAMAP: MraZ; InterPro IPR020603:IPR003444; KEGG: ssm:Spirs_1544 MraZ protein; PFAM: MraZ domain; SPTR: Protein MraZ; TIGRFAM: MraZ; IMG [...]
AEC01885.1 protein networkhttps://string-db.org/network/760011.Spico_0657(1->4)-alpha-D-glucan branching enzyme; COGs: COG1543 conserved hypothetical protein; InterPro IPR004300:IPR015293; KEGG: ssm:Spirs_1542 domain of unknown function DUF1957; PFAM: Domain of unknow [...]
AEC01886.1 protein networkhttps://string-db.org/network/760011.Spico_0658KEGG: sta:STHERM_c08890 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956942.
AEC01887.1 protein networkhttps://string-db.org/network/760011.Spico_0659Glycoside hydrolase family 57; InterPro IPR004300; KEGG: ssm:Spirs_1540 glycoside hydrolase family 57; PFAM: Glycoside hydrolase, family 57, N-terminal; SPTR: Glycoside hydrolase, family 57; IMG [...]
AEC01888.1 protein networkhttps://string-db.org/network/760011.Spico_0660DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
nadK protein networkhttps://string-db.org/network/760011.Spico_0661Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosph [...]
AEC01890.1 protein networkhttps://string-db.org/network/760011.Spico_0662DegT/DnrJ/EryC1/StrS aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: ssm:Spirs_1533 DegT/ [...]
AEC01891.1 protein networkhttps://string-db.org/network/760011.Spico_0663Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against [...]
AEC01892.1 protein networkhttps://string-db.org/network/760011.Spico_0664Magnesium chelatase ChlI subunit; COGs: COG0606 ATPase with chaperone activity; InterPro IPR000523:IPR003593; KEGG: sta:STHERM_c05260 hypothetical protein; PFAM: Magnesium chelatase, ChlI subunit [...]
AEC01893.1 protein networkhttps://string-db.org/network/760011.Spico_0667Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ara:Arad_4624 sugar ABC transporter; PF [...]
AEC01894.1 protein networkhttps://string-db.org/network/760011.Spico_0668Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: kfl:Kfla_2100 binding-protein-dependent t [...]
AEC01895.1 protein networkhttps://string-db.org/network/760011.Spico_0669Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: ach:Achl_3128 extracellular solute-binding protein fa [...]
AEC01896.1 protein networkhttps://string-db.org/network/760011.Spico_0670KEGG: cpy:Cphy_3399 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956958.
AEC01897.1 protein networkhttps://string-db.org/network/760011.Spico_0671Xylan 1,4-beta-xylosidase; COGs: COG3507 Beta-xylosidase; InterPro IPR006710; KEGG: cpy:Cphy_3398 glycoside hydrolase family protein; PFAM: Glycoside hydrolase, family 43; PRIAM: Xylan 1,4-beta-x [...]
AEC01898.1 protein networkhttps://string-db.org/network/760011.Spico_0672Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006121:IPR008250:IPR005834:IPR006404:IPR 006416:IPR001757; KEGG: efa:EF1400 cadmium-translocating P-type [...]
fusA protein networkhttps://string-db.org/network/760011.Spico_0673Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocat [...]
AEC01900.1 protein networkhttps://string-db.org/network/760011.Spico_0674COGs: COG0480 Translation elongation factors (GTPase); InterPro IPR000795:IPR005517:IPR000640:IPR005225; KEGG: ssm:Spirs_2536 small GTP-binding protein; PFAM: Translation elongation factor EFG/EF [...]
trmB protein networkhttps://string-db.org/network/760011.Spico_0675tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
mfd protein networkhttps://string-db.org/network/760011.Spico_0676Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated tr [...]
AEC01903.1 protein networkhttps://string-db.org/network/760011.Spico_0677Inositol monophosphatase; COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR000760; KEGG: ssm:Spirs_3133 inositol monophosphatase; PFAM: Inositol monophosp [...]
AEC01904.1 protein networkhttps://string-db.org/network/760011.Spico_0678Protein of unknown function DUF165; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q [...]
AEC01905.1 protein networkhttps://string-db.org/network/760011.Spico_0679KEGG: ssm:Spirs_1463 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956969.
nrdR protein networkhttps://string-db.org/network/760011.Spico_0680Transcriptional repressor nrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
AEC01907.1 protein networkhttps://string-db.org/network/760011.Spico_0681Metal-dependent phosphohydrolase HD sub domain protein; COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR006674:IPR003607; KEGG: ssm:Spirs_1451 metal-dependent phosphohydrolase HD sub domain p [...]
AEC01908.1 protein networkhttps://string-db.org/network/760011.Spico_0682Hypothetical protein; KEGG: ath:AT3G44920 ATCHX11; monovalent cation:proton antiporter/ sodium:hydrogen antiporter; SPTR: Cation/H(+) antiporter 11; IMG reference gene:2503956972.
aroK protein networkhttps://string-db.org/network/760011.Spico_0683Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
aroC protein networkhttps://string-db.org/network/760011.Spico_0684Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
AEC01911.1 protein networkhttps://string-db.org/network/760011.Spico_0685Helicase domain protein; COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR006935:IPR001650:IPR014001; KEGG: ssm:Spirs_2851 helicase domain protein; PFAM: Helicase, C-terminal; Res [...]
AEC01912.1 protein networkhttps://string-db.org/network/760011.Spico_0686KEGG: ssm:Spirs_2852 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956976.
aroD protein networkhttps://string-db.org/network/760011.Spico_06873-dehydroquinate dehydratase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydro [...]
AEC01914.1 protein networkhttps://string-db.org/network/760011.Spico_0688COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439:IPR003593; KEGG: ssm:Spirs_2861 ABC transporter related protein; PFAM: ABC transporter-like; [...]
AEC01915.1 protein networkhttps://string-db.org/network/760011.Spico_0689Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucle [...]
rpsB protein networkhttps://string-db.org/network/760011.Spico_0690COGs: COG0052 Ribosomal protein S2; InterPro IPR001865:IPR005706; KEGG: ssm:Spirs_2864 ribosomal protein S2; PFAM: Ribosomal protein S2; SPTR: 30S ribosomal protein S2; TIGRFAM: Ribosomal protein [...]
tsf protein networkhttps://string-db.org/network/760011.Spico_0691Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the [...]
frr protein networkhttps://string-db.org/network/760011.Spico_0692Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
AEC01919.1 protein networkhttps://string-db.org/network/760011.Spico_0693Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
AEC01920.1 protein networkhttps://string-db.org/network/760011.Spico_0694COGs: COG4589 CDP-diglyceride synthetase/phosphatidate cytidylyltransferase; InterPro IPR000374; KEGG: tde:TDE2343 phosphatidate cytidylyltransferase; PFAM: Phosphatidate cytidylyltransferase; SP [...]
dxr protein networkhttps://string-db.org/network/760011.Spico_06951-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Be [...]
AEC01922.1 protein networkhttps://string-db.org/network/760011.Spico_0696Peptidase M50; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR008915; KEGG: ssm:Spirs_2870 membrane-associated zinc metalloprotease; PFAM: Peptidase M50; SPTR: Putative un [...]
AEC01923.1 protein networkhttps://string-db.org/network/760011.Spico_0697Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
rplI protein networkhttps://string-db.org/network/760011.Spico_069850S ribosomal protein L9; Binds to the 23S rRNA.
AEC01925.1 protein networkhttps://string-db.org/network/760011.Spico_0699KEGG: sta:STHERM_c13160 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956989.
rpsR protein networkhttps://string-db.org/network/760011.Spico_0700SSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial riboso [...]
AEC01927.1 protein networkhttps://string-db.org/network/760011.Spico_0701Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action du [...]
rpsF protein networkhttps://string-db.org/network/760011.Spico_070230S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
AEC01929.1 protein networkhttps://string-db.org/network/760011.Spico_0703COGs: COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; InterPro IPR013221:IPR004101:IPR005762; KEGG: sta:STHERM_c03310 UDP-N-acetylmuramoylalanine--D-glutamate ligase; PFAM: Mur ligase, ce [...]
AEC01930.1 protein networkhttps://string-db.org/network/760011.Spico_0704Methicillin resistance protein; COGs: COG2348 Uncharacterized protein involved in methicillin resistance; InterPro IPR003447; KEGG: ssm:Spirs_2888 methicillin resistance protein; PFAM: Methicilli [...]
metG protein networkhttps://string-db.org/network/760011.Spico_0705methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
AEC01932.1 protein networkhttps://string-db.org/network/760011.Spico_0706Protease FtsH subunit HflK; HflC and HflK could encode or regulate a protease.
AEC01933.1 protein networkhttps://string-db.org/network/760011.Spico_0707HflC protein; HflC and HflK could regulate a protease.
AEC01934.1 protein networkhttps://string-db.org/network/760011.Spico_0708KEGG: atu:Atu2463 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956998.
AEC01935.1 protein networkhttps://string-db.org/network/760011.Spico_0709KEGG: clj:CLJU_c23260 hypothetical protein; SPTR: Uncharacterized membrane protein; IMG reference gene:2503956999.
AEC01936.1 protein networkhttps://string-db.org/network/760011.Spico_0710ABC transporter related protein; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: kol:Kole_0152 ABC transporter related; PFAM: ABC transport [...]
argG protein networkhttps://string-db.org/network/760011.Spico_0711COGs: COG0137 Argininosuccinate synthase; HAMAP: Argininosuccinate synthase; InterPro IPR001518; KEGG: trq:TRQ2_1045 argininosuccinate synthase; PFAM: Argininosuccinate synthase; PRIAM: Argininos [...]
AEC01938.1 protein networkhttps://string-db.org/network/760011.Spico_0712Regulatory protein ArsR; InterPro IPR001845; KEGG: clo:HMPREF0868_0433 transcriptional repressor SmtB family protein; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulat [...]
AEC01939.1 protein networkhttps://string-db.org/network/760011.Spico_0713COGs: COG3661 Alpha-glucuronidase; InterPro IPR011100:IPR011099; KEGG: rbi:RB2501_04530 alpha-glucuronidase; PFAM: Glycosyl hydrolase 67 middle; Glycosyl hydrolase 67, C-terminal; PRIAM: Alpha-gl [...]
AEC01940.1 protein networkhttps://string-db.org/network/760011.Spico_0714Sugar ABC transporter substrate-binding protein; COGs: COG1653 ABC-type sugar transport system periplasmic component; KEGG: sta:STHERM_c18860 sugar ABC transporter substrate-binding protein; SPTR [...]
AEC01941.1 protein networkhttps://string-db.org/network/760011.Spico_0715Binding-protein-dependent transport systems inner membrane component; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: sta:STHERM_c18870 transporter; PF [...]
AEC01942.1 protein networkhttps://string-db.org/network/760011.Spico_0716Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: sta:STHERM_c18880 transporter; P [...]
AEC01943.1 protein networkhttps://string-db.org/network/760011.Spico_0717Transcriptional regulator, GntR family with LacI sensor; COGs: COG1609 Transcriptional regulators; InterPro IPR000524:IPR001761; KEGG: ttm:Tthe_0670 transcriptional regulator, GntR family with La [...]
AEC01944.1 protein networkhttps://string-db.org/network/760011.Spico_0718COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104:IPR006103; KEGG: pjd:Pjdr2_2523 glycoside hydrolase family 2 sugar binding; PFAM: Glycoside hydrolase, family 2, carbohydra [...]
AEC01945.1 protein networkhttps://string-db.org/network/760011.Spico_0719InterPro IPR001087; KEGG: sli:Slin_3977 lipolytic protein G-D-S-L family; PFAM: Lipase, GDSL; SPTR: Putative acetylhydrolase; IMG reference gene:2503957009; PFAM: GDSL-like Lipase/Acylhydrolase.
AEC01946.1 protein networkhttps://string-db.org/network/760011.Spico_0720COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764:IPR002772; KEGG: cbe:Cbei_4974 glycoside hydrolase family 3 protein; PFAM: Glycoside hydrolase, family 3, C-terminal; Glycos [...]
AEC01947.1 protein networkhttps://string-db.org/network/760011.Spico_0721Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: pjd:Pjdr2_5596 binding-protein-dependent [...]
AEC01948.1 protein networkhttps://string-db.org/network/760011.Spico_0722Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: pjd:Pjdr2_5597 binding-protein-dependen [...]
AEC01949.1 protein networkhttps://string-db.org/network/760011.Spico_0723Carbohydrate ABC transporter substrate-binding protein, CUT1 family; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: pjd:Pjdr2_5598 extracellular so [...]
AEC01950.1 protein networkhttps://string-db.org/network/760011.Spico_0724InterPro IPR000852; KEGG: ttm:Tthe_0982 xylan 1,4-beta-xylosidase; PFAM: Glycoside hydrolase, family 52; PRIAM: Xylan 1,4-beta-xylosidase; SPTR: Xylan 1,4-beta-xylosidase; IMG reference gene:2503 [...]
AEC01951.1 protein networkhttps://string-db.org/network/760011.Spico_0725Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: ot [...]
AEC01952.1 protein networkhttps://string-db.org/network/760011.Spico_0726Histidine kinase; COGs: COG1609 Transcriptional regulators; InterPro IPR001761:IPR003594; KEGG: ssm:Spirs_1217 ATP-binding region ATPase domain protein; PFAM: ATPase-like, ATP-binding domain; Per [...]
adk protein networkhttps://string-db.org/network/760011.Spico_0727Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
AEC01954.1 protein networkhttps://string-db.org/network/760011.Spico_0728COGs: COG0035 Uracil phosphoribosyltransferase; KEGG: ssm:Spirs_1527 phosphoribosyl transferase domain-containing protein; SPTR: Phosphoribosyl transferase domain protein; IMG reference gene:2503 [...]
AEC01955.1 protein networkhttps://string-db.org/network/760011.Spico_0729KEGG: aae:aq_854 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957019.
rnhA protein networkhttps://string-db.org/network/760011.Spico_0730RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
AEC01957.1 protein networkhttps://string-db.org/network/760011.Spico_0731COGs: COG0760 Parvulin-like peptidyl-prolyl isomerase; InterPro IPR000297; KEGG: dsh:Dshi_3566 PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, PpiC-type; [...]
AEC01958.1 protein networkhttps://string-db.org/network/760011.Spico_0732Adenylate cyclase; InterPro IPR008172; KEGG: ssm:Spirs_2340 adenylyl cyclase CyaB; PFAM: Adenylate cyclase; SPTR: Putative uncharacterized protein; IMG reference gene:2503957022; PFAM: CYTH domai [...]
AEC01959.1 protein networkhttps://string-db.org/network/760011.Spico_0733KEGG: ssm:Spirs_2341 hypothetical protein; SPTR: Putative membrane protein; IMG reference gene:2503957023.
AEC01960.1 protein networkhttps://string-db.org/network/760011.Spico_0734InterPro IPR011701; KEGG: sfu:Sfum_0552 major facilitator transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; IMG reference gene:2503957024; PFAM: M [...]
AEC01961.1 protein networkhttps://string-db.org/network/760011.Spico_0735COGs: COG1963 conserved hypothetical protein; InterPro IPR003832; KEGG: msv:Mesil_2435 acid phosphatase/vanadium-dependent haloperoxidase related protein; PFAM: Acid phosphatase/vanadium-dependen [...]
AEC01962.1 protein networkhttps://string-db.org/network/760011.Spico_0736Extracellular solute-binding protein family 3; COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638; KEGG: dal:Dalk_1255 extrac [...]
AEC01963.1 protein networkhttps://string-db.org/network/760011.Spico_0737Extracellular solute-binding protein family 3; COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638; KEGG: dvl:Dvul_1824 extrac [...]
AEC01964.1 protein networkhttps://string-db.org/network/760011.Spico_0738Integrase catalytic region; COGs: COG2826 Transposase and inactivated derivatives IS30 family; InterPro IPR001584; KEGG: ccb:Clocel_0985 integrase catalytic region; PFAM: Integrase, catalytic cor [...]
AEC01965.1 protein networkhttps://string-db.org/network/760011.Spico_0739Amino acid ABC transporter membrane protein, PAAT family; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR000515:IPR010065; KEGG: gsu:GSU3405 amino acid ABC tra [...]
AEC01966.1 protein networkhttps://string-db.org/network/760011.Spico_0740Amino acid ABC transporter ATP-binding protein, PAAT family; COGs: COG1126 ABC-type polar amino acid transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: afu:AF0680 glutamine AB [...]
AEC01967.1 protein networkhttps://string-db.org/network/760011.Spico_0741Transposase IS4 family protein; COGs: COG5421 Transposase; InterPro IPR002559; KEGG: cob:COB47_1677 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family prote [...]
AEC01968.1 protein networkhttps://string-db.org/network/760011.Spico_0743Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: ssm:Spirs_2381 Fmu (Sun) domain protein; PFAM: Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1 [...]
AEC01969.1 protein networkhttps://string-db.org/network/760011.Spico_0744UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: ssm:Spirs_2383 UvrD/REP helicase; PFAM: DNA helicase, UvrD/REP type; SPTR: ATP-dependent DNA helicas [...]
AEC01970.1 protein networkhttps://string-db.org/network/760011.Spico_0745Hypothetical protein; KEGG: tgu:100218726 mitogen-activated protein kinase 6; SPTR: Mitogen-activated protein kinase 6; IMG reference gene:2503957035.
AEC01971.1 protein networkhttps://string-db.org/network/760011.Spico_0746Cobyrinic acid ac-diamide synthase; COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: bhy:BHWA1_02684 plasmid partition protein; PFAM: Cobyrinic acid a,c-diamide [...]
AEC01972.1 protein networkhttps://string-db.org/network/760011.Spico_0747Broad-specificity cellobiase; COGs: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; InterPro IPR001360:IPR017736; KEGG: mrb:Mrub_0288 beta-galactosidase; PFAM: Glycoside [...]
AEC01973.1 protein networkhttps://string-db.org/network/760011.Spico_0748Exodeoxyribonuclease III Xth; COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR000097:IPR004808; KEGG: aoe:Clos_2318 exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; [...]
AEC01974.1 protein networkhttps://string-db.org/network/760011.Spico_0749GTP-binding protein TypA; COGs: COG1217 membrane GTPase involved in stress response; InterProIPR000795:IPR004161:IPR000640:IPR005225:IPR 006298; KEGG: ssm:Spirs_3901 GTP-binding protein TypA; PFA [...]
AEC01975.1 protein networkhttps://string-db.org/network/760011.Spico_0750GCN5-related N-acetyltransferase; InterPro IPR000182; KEGG: ret:RHE_CH01554 acetyltransferase protein; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative acetyltransferase; IMG [...]
AEC01976.1 protein networkhttps://string-db.org/network/760011.Spico_0751COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: str:Sterm_0308 alpha/beta fold family hydrolase, putative; PFAM: Alpha/beta hydrolase fold [...]
AEC01977.1 protein networkhttps://string-db.org/network/760011.Spico_0752Beta-lactamase domain protein; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; InterPro IPR001279:IPR011108; KEGG: cce:Ccel_1759 RNA-metabolising metallo-beta-lac [...]
AEC01978.1 protein networkhttps://string-db.org/network/760011.Spico_0753Putative PTS IIA-like nitrogen-regulatory protein PtsN; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: rba:RB8584 PTS system, [...]
AEC01979.1 protein networkhttps://string-db.org/network/760011.Spico_0754InterPro IPR006016; KEGG: ssm:Spirs_3105 UspA domain protein; PFAM: UspA; SPTR: UspA domain protein; IMG reference gene:2503957048; PFAM: Universal stress protein family.
atpD protein networkhttps://string-db.org/network/760011.Spico_0755V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.
atpB protein networkhttps://string-db.org/network/760011.Spico_0756V-type ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.
atpA protein networkhttps://string-db.org/network/760011.Spico_0757V-type ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta ch [...]
AEC01983.1 protein networkhttps://string-db.org/network/760011.Spico_0758InterPro IPR002842; KEGG: ssm:Spirs_3109 H+transporting two-sector ATPase E subunit; PFAM: ATPase, V1/A1 complex, subunit E; SPTR: Vacuolar H+-ATPase E subunit; IMG reference gene:2503957052; PFA [...]
AEC01984.1 protein networkhttps://string-db.org/network/760011.Spico_0759COGs: COG1436 H+-ATPase subunit F; InterPro IPR008218; KEGG: ssm:Spirs_3110 vacuolar H+transporting two-sector ATPase F subunit; PFAM: ATPase, V1/A1 complex, subunit F; SPTR: A1A0 archaeal ATP sy [...]
AEC01985.1 protein networkhttps://string-db.org/network/760011.Spico_0760InterPro IPR002379; KEGG: ssm:Spirs_3111 H+transporting two-sector ATPase C subunit; PFAM: ATPase, F0/V0 complex, subunit C; SPTR: V-ATPase F-subunit; IMG reference gene:2503957054; PFAM: ATP syn [...]
AEC01986.1 protein networkhttps://string-db.org/network/760011.Spico_0761V-type ATPase 116 kDa subunit; COGs: COG1269 H+-ATPase subunit I; InterPro IPR002490; KEGG: ssm:Spirs_3112 V-type ATPase 116 kDa subunit; PFAM: ATPase, V0/A0 complex, 116kDa subunit; SPTR: Putati [...]
AEC01987.1 protein networkhttps://string-db.org/network/760011.Spico_0762COGs: COG1527 H+-ATPase subunit C; InterPro IPR002843; KEGG: ssm:Spirs_3113 H+transporting two-sector ATPase C (AC39) subunit; PFAM: ATPase, V0/A0 complex, subunit C/D; SPTR: H(+)-transporting tw [...]
AEC01988.1 protein networkhttps://string-db.org/network/760011.Spico_0763KEGG: sna:Snas_1610 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957057.
AEC01989.1 protein networkhttps://string-db.org/network/760011.Spico_0764Transposase, IS605 OrfB family; COGs: COG0675 Transposase and inactivated derivatives; InterPro IPR001959:IPR010095; KEGG: xfm:Xfasm12_1563 transposase OrfB; PFAM: Transposase, probable, IS891/IS [...]
AEC01990.1 protein networkhttps://string-db.org/network/760011.Spico_0765Resolvase domain protein; COGs: COG2452 site-specific integrase-resolvase; InterPro IPR000551:IPR006119; KEGG: xfm:Xfasm12_1564 hypothetical protein; PFAM: Resolvase, N-terminal; HTH transcriptio [...]
AEC01991.1 protein networkhttps://string-db.org/network/760011.Spico_0766KEGG: bcb:BCB4264_A3629 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957060.
AEC01992.1 protein networkhttps://string-db.org/network/760011.Spico_0767Filamentation induced by cAMP protein Fic; COGs: COG2184 Protein involved in cell division; InterPro IPR003812; KEGG: ajs:Ajs_4242 filamentation induced by cAMP protein Fic; PFAM: Filamentation i [...]
AEC01993.1 protein networkhttps://string-db.org/network/760011.Spico_0768Oligo-1,6-glucosidase; COGs: COG0366 Glycosidase; InterPro IPR006047:IPR006589; KEGG: csc:Csac_2428 alpha amylase, catalytic region; PFAM: Glycosyl hydrolase, family 13, catalytic domain; PRIAM: [...]
AEC01994.1 protein networkhttps://string-db.org/network/760011.Spico_0769COGs: COG3345 Alpha-galactosidase; InterPro IPR000111; KEGG: cpy:Cphy_1936 glycoside hydrolase clan GH-D; PFAM: Glycoside hydrolase, clan GH-D; PRIAM: Alpha-galactosidase; SPTR: Glycoside hydrola [...]
AEC01995.1 protein networkhttps://string-db.org/network/760011.Spico_0770COGs: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; InterPro IPR001360; KEGG: cpy:Cphy_1937 glycoside hydrolase family protein; PFAM: Glycoside hydrolase, family 1; PRI [...]
AEC01996.1 protein networkhttps://string-db.org/network/760011.Spico_0771Sugar (Glycoside-Pentoside-Hexuronide) transporter; COGs: COG2211 Na+/melibiose symporter and related transporter; InterPro IPR011701:IPR001927; KEGG: cpy:Cphy_1935 sugar (glycoside-pentoside-hex [...]
AEC01997.1 protein networkhttps://string-db.org/network/760011.Spico_0772AzlC family protein; COGs: COG1296 branched-chain amino acid permease (azaleucine resistance); InterPro IPR011606; KEGG: gwc:GWCH70_0661 AzlC family protein; PFAM: Branched-chain amino acid trans [...]
AEC01998.1 protein networkhttps://string-db.org/network/760011.Spico_0773InterPro IPR008407; KEGG: bse:Bsel_1519 branched-chain amino acid transport; PFAM: Branched-chain amino acid transport, AzlD; SPTR: Putative uncharacterized protein; IMG reference gene:2503957068 [...]
AEC01999.1 protein networkhttps://string-db.org/network/760011.Spico_0774KEGG: fbc:FB2170_04545 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957069.
AEC02000.1 protein networkhttps://string-db.org/network/760011.Spico_0775KEGG: paa:Paes_0399 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957070.
AEC02001.1 protein networkhttps://string-db.org/network/760011.Spico_0776COGs: COG0824 thioesterase; InterPro IPR006683:IPR006684; KEGG: asu:Asuc_1795 Pol-Pal system-associated acyl-CoA thioesterase; PFAM: Thioesterase superfamily; SPTR: Pol-Pal system-associated acyl [...]
AEC02002.1 protein networkhttps://string-db.org/network/760011.Spico_0777COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR022644:IPR022643; KEGG: ssm:Spirs_1460 Orn/DAP/Arg decarboxylase 2; PFAM: Orn/DAP/Arg decarboxylase 2, C-terminal; Orn/DAP/Arg decarboxyla [...]
dapL protein networkhttps://string-db.org/network/760011.Spico_0778LL-diaminopimelate aminotransferase apoenzyme; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct c [...]
dapA protein networkhttps://string-db.org/network/760011.Spico_0779Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
dapB protein networkhttps://string-db.org/network/760011.Spico_0780Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
AEC02006.1 protein networkhttps://string-db.org/network/760011.Spico_0781DNA topoisomerase III; COGs: COG0550 Topoisomerase IA; InterProIPR006171:IPR013497:IPR003601:IPR003602:IPR 005738; KEGG: dhd:Dhaf_4786 DNA topoisomerase III; PFAM: DNA topoisomerase, type IA, cen [...]
AEC02007.1 protein networkhttps://string-db.org/network/760011.Spico_07824Fe-4S ferredoxin iron-sulfur binding domain-containing protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
xseA protein networkhttps://string-db.org/network/760011.Spico_0783Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleo [...]
xseB protein networkhttps://string-db.org/network/760011.Spico_0784Exodeoxyribonuclease 7 small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleo [...]
AEC02010.1 protein networkhttps://string-db.org/network/760011.Spico_0785ThiJ/PfpI domain-containing protein; COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR002818; KEGG: clj:CLJU_c17590 putati [...]
AEC02011.1 protein networkhttps://string-db.org/network/760011.Spico_0786COGs: COG2309 Leucyl aminopeptidase (aminopeptidase T); KEGG: ssm:Spirs_1009 peptidase M29 aminopeptidase II; SPTR: Peptidase M29 aminopeptidase II; IMG reference gene:2503957081; PFAM: Thermophi [...]
AEC02012.1 protein networkhttps://string-db.org/network/760011.Spico_0787COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: tde:TDE1083 RNA pseudouridylate synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Pseudouridi [...]
AEC02013.1 protein networkhttps://string-db.org/network/760011.Spico_0788Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR000408; KEGG: ttm:Tthe_2617 S-layer domain protein; PFAM: [...]
AEC02014.1 protein networkhttps://string-db.org/network/760011.Spico_0789Protein of unknown function UPF0005; COGs: COG0670 Integral membrane protein interacts with FtsH; InterPro IPR006214; KEGG: ssm:Spirs_1304 protein of unknown function UPF0005; PFAM: Inhibitor of [...]
AEC02015.1 protein networkhttps://string-db.org/network/760011.Spico_0790Hypothetical protein; KEGG: srt:Srot_2429 ABC transporter-like protein; SPTR: ABC transporter related protein; IMG reference gene:2503957085.
AEC02016.1 protein networkhttps://string-db.org/network/760011.Spico_0791Recombination protein MgsA; COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003959:IPR003593; KEGG: ssm:Spirs_1297 AAA ATPase central domain p [...]
tig protein networkhttps://string-db.org/network/760011.Spico_0792Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs t [...]
clpP protein networkhttps://string-db.org/network/760011.Spico_0793ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the de [...]
clpX protein networkhttps://string-db.org/network/760011.Spico_0794ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in th [...]
AEC02020.1 protein networkhttps://string-db.org/network/760011.Spico_0795Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: tde:TDE1479 DHH superfamily protein, subfamily 1; PFAM: Phosphoesterase, [...]
AEC02021.1 protein networkhttps://string-db.org/network/760011.Spico_0796KEGG: ssm:Spirs_1290 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957096.
AEC02022.1 protein networkhttps://string-db.org/network/760011.Spico_0797Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine n [...]
AEC02023.1 protein networkhttps://string-db.org/network/760011.Spico_0798Oligopeptidase F; COGs: COG1164 Oligoendopeptidase F; InterPro IPR013647:IPR001567:IPR004438; KEGG: ssm:Spirs_1288 oligoendopeptidase F; PFAM: Peptidase M3A/M3B, thimet/oligopeptidase F; Peptidas [...]
AEC02026.1 protein networkhttps://string-db.org/network/760011.Spico_0801Hypothetical protein; IMG reference gene:2503957102.
AEC02027.1 protein networkhttps://string-db.org/network/760011.Spico_0802KEGG: afv:AFLA_136820 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957103.
AEC02028.1 protein networkhttps://string-db.org/network/760011.Spico_0803KEGG: ath:AT2G32240 hypothetical protein; SPTR: Whole genome shotgun sequence of line PN40024, scaffold_16.assembly12x; IMG reference gene:2503957104.
AEC02029.1 protein networkhttps://string-db.org/network/760011.Spico_0804InterPro IPR008160; KEGG: spv:SPH_0115 phage minor structural protein; PFAM: Collagen triple helix repeat; SPTR: Phage minor structural protein; IMG reference gene:2503957105; PFAM: Collagen trip [...]
AEC02030.1 protein networkhttps://string-db.org/network/760011.Spico_0805Hypothetical protein; KEGG: rce:RC1_0084 phage tail tape measure protein, putative; SPTR: Phage tail tape measure protein, putative; IMG reference gene:2503957106.
AEC02031.1 protein networkhttps://string-db.org/network/760011.Spico_0806Hypothetical protein; IMG reference gene:2503957107.
AEC02032.1 protein networkhttps://string-db.org/network/760011.Spico_0807Hypothetical protein; KEGG: smf:Smon_0099 cell division protein FtsZ; SPTR: Cell division protein ftsZ; IMG reference gene:2503957108.
AEC02033.1 protein networkhttps://string-db.org/network/760011.Spico_0808KEGG: cim:CIMG_07117 hypothetical protein; SPTR: Putative ribose-phosphate pyrophosphokinase; IMG reference gene:2503957109.
AEC02034.1 protein networkhttps://string-db.org/network/760011.Spico_0809Hypothetical protein; KEGG: cai:Caci_5320 amidohydrolase 3; SPTR: Amidohydrolase 3; IMG reference gene:2503957110.
AEC02035.1 protein networkhttps://string-db.org/network/760011.Spico_0810Hypothetical protein; KEGG: ecb:100051325 similar to Signal recognition particle 68 kDa protein (SRP68); SPTR: Uncharacterized protein; IMG reference gene:2503957111.
AEC02036.1 protein networkhttps://string-db.org/network/760011.Spico_0811Hypothetical protein; KEGG: avi:Avi_2997 Mu-like prophage protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957112; PFAM: Phage virion morphogenesis family.
AEC02037.1 protein networkhttps://string-db.org/network/760011.Spico_0812KEGG: dap:Dacet_2235 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957113.
AEC02038.1 protein networkhttps://string-db.org/network/760011.Spico_0813KEGG: dde:Dde_3377 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957114.
AEC02039.1 protein networkhttps://string-db.org/network/760011.Spico_0814KEGG: dap:Dacet_2233 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957115.
AEC02040.1 protein networkhttps://string-db.org/network/760011.Spico_0816InterPro IPR006528; KEGG: mrb:Mrub_1967 phage head morphogenesis protein, SPP1 gp7 family; PFAM: Phage putative head morphogenesis protein, SPP1 gp7; SPTR: Virion morphogenesis protein; TIGRFAM: [...]
AEC02041.1 protein networkhttps://string-db.org/network/760011.Spico_0817Protein of unknown function DUF935; COGs: COG4383 Mu-like prophage protein gp29; InterPro IPR009279; KEGG: dap:Dacet_2219 hypothetical protein; PFAM: Protein of unknown function DUF935; SPTR: Put [...]
AEC02042.1 protein networkhttps://string-db.org/network/760011.Spico_0818KEGG: hth:HTH_0882 phage uncharacterized protein; SPTR: Phage uncharacterized protein; IMG reference gene:2503957119; PFAM: Terminase-like family.
AEC02043.1 protein networkhttps://string-db.org/network/760011.Spico_0819KEGG: amt:Amet_1950 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957120; PFAM: Protein of unknown function (DUF3486).
AEC02044.1 protein networkhttps://string-db.org/network/760011.Spico_0820KEGG: hth:HTH_0884 hypothetical protein; SPTR: Predicted protein; IMG reference gene:2503957121.
AEC02045.1 protein networkhttps://string-db.org/network/760011.Spico_0821KEGG: dtu:Dtur_1626 SMC domain protein; SPTR: SMC domain protein; IMG reference gene:2503957122.
AEC02046.1 protein networkhttps://string-db.org/network/760011.Spico_0822Hypothetical protein; KEGG: tel:tll0573 putative porin; major outer membrane protein; SPTR: Tll0573 protein; IMG reference gene:2503957123.
AEC02047.1 protein networkhttps://string-db.org/network/760011.Spico_0823Hypothetical protein; KEGG: hch:HCH_02233 cell wall biosynthesis glycosyltransferase; SPTR: Glycosyltransferase involved in cell wall biogenesis; IMG reference gene:2503957124.
AEC02048.1 protein networkhttps://string-db.org/network/760011.Spico_0824KEGG: emi:Emin_1453 putative phage-related protein; SPTR: Putative phage-related protein; IMG reference gene:2503957125.
AEC02049.1 protein networkhttps://string-db.org/network/760011.Spico_0825KEGG: zpr:ZPR_0434 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957126.
AEC02050.1 protein networkhttps://string-db.org/network/760011.Spico_0826Hypothetical protein; KEGG: dre:550523 zgc:110200; SPTR: Non-LEE encoded type III effector C; IMG reference gene:2503957127.
AEC02051.1 protein networkhttps://string-db.org/network/760011.Spico_0827Hypothetical protein; KEGG: pth:PTH_2540 phosphoribosylamine-glycine ligase; SPTR: Phosphoribosylamine-glycine ligase; IMG reference gene:2503957128.
AEC02052.1 protein networkhttps://string-db.org/network/760011.Spico_0828Putative phage repressor; COGs: COG2932 transcriptional regulator protein; InterPro IPR001387:IPR019759; KEGG: lhk:LHK_01994 transcriptional regulator; PFAM: Helix-turn-helix type 3; Peptidase S2 [...]
AEC02053.1 protein networkhttps://string-db.org/network/760011.Spico_0829Hypothetical protein; KEGG: pzu:PHZ_c1565 predicted endonuclease containing a URI domain; SPTR: Predicted endonuclease containing a URI domain; IMG reference gene:2503957130.
AEC02054.1 protein networkhttps://string-db.org/network/760011.Spico_0830KEGG: pyo:PY04213 hypothetical protein; SPTR: Death-inducer obliterator 1; IMG reference gene:2503957131.
AEC02055.1 protein networkhttps://string-db.org/network/760011.Spico_0831Hypothetical protein; KEGG: ape:APE_0946 succinate dehydrogenase iron-sulfur subunit; SPTR: Succinate dehydrogenase subunit B; IMG reference gene:2503957132.
AEC02056.1 protein networkhttps://string-db.org/network/760011.Spico_0832Helix-turn-helix domain protein; InterPro IPR001387; KEGG: bfs:BF3179 DNA-binding protein; PFAM: Helix-turn-helix type 3; SPTR: Putative uncharacterized protein; IMG reference gene:2503957133; PF [...]
AEC02057.1 protein networkhttps://string-db.org/network/760011.Spico_0833Hypothetical protein; KEGG: dbr:Deba_1609 integrase catalytic region; SPTR: Putative uncharacterized protein; IMG reference gene:2503957134; PFAM: Bacteriophage Mu transposase.
AEC02058.1 protein networkhttps://string-db.org/network/760011.Spico_0834Hypothetical protein; COGs: COG2842 Uncharacterized ATPase putative transposase; KEGG: dde:Dde_3351 bacteriophage DNA transposition B protein; SPTR: Putative uncharacterized protein; IMG referenc [...]
AEC02059.1 protein networkhttps://string-db.org/network/760011.Spico_0835KEGG: dde:Dde_3352 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957136.
AEC02060.1 protein networkhttps://string-db.org/network/760011.Spico_0836Hypothetical protein; KEGG: rce:RC1_1103 GemA, modulation of host genes; SPTR: Putative uncharacterized protein; IMG reference gene:2503957137; PFAM: Protein of unknown function (DUF1018).
AEC02061.1 protein networkhttps://string-db.org/network/760011.Spico_0837KEGG: aat:D11S_0001 putative sulfate transport protein CysZ; SPTR: Putative sulfate transport protein CysZ; IMG reference gene:2503957138; PFAM: Protein of unknown function (DUF3164).
AEC02062.1 protein networkhttps://string-db.org/network/760011.Spico_0838KEGG: ctc:CTC02237 hypothetical protein; SPTR: Conserved protein; IMG reference gene:2503957139.
AEC02063.1 protein networkhttps://string-db.org/network/760011.Spico_0839KEGG: sbi:SORBI_04g009980 hypothetical protein; SPTR: Lantibiotic mersacidin modifying enzyme; IMG reference gene:2503957140.
AEC02065.1 protein networkhttps://string-db.org/network/760011.Spico_0841Integrase family protein; InterPro IPR002104; KEGG: ssm:Spirs_R0031 integrase family protein; PFAM: Integrase, catalytic core, phage; SPTR: Tn554-related transposase B; IMG reference gene:2503957 [...]
AEC02066.1 protein networkhttps://string-db.org/network/760011.Spico_0842InterPro IPR004360; KEGG: str:Sterm_2228 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxalase family protein; IMG refer [...]
nth protein networkhttps://string-db.org/network/760011.Spico_0843DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines fr [...]
AEC02068.1 protein networkhttps://string-db.org/network/760011.Spico_0844KEGG: ckr:CKR_1799 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957147.
AEC02069.1 protein networkhttps://string-db.org/network/760011.Spico_0845Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radic [...]
AEC02070.1 protein networkhttps://string-db.org/network/760011.Spico_0846Ribonucleoside-triphosphate reductase class III catalytic subunit; COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR005144:IPR012833; KEGG: aoe:Clos_1144 anaerobi [...]
potA protein networkhttps://string-db.org/network/760011.Spico_0847Spermidine/putrescine ABC transporter ATPase subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system [...]
AEC02072.1 protein networkhttps://string-db.org/network/760011.Spico_0848Binding-protein-dependent transport systems inner membrane component; COGs: COG1176 ABC-type spermidine/putrescine transport system permease component I; InterPro IPR000515; KEGG: tpp:TPASS_0653 [...]
AEC02073.1 protein networkhttps://string-db.org/network/760011.Spico_0849Binding-protein-dependent transport systems inner membrane component; COGs: COG1177 ABC-type spermidine/putrescine transport system permease component II; InterPro IPR000515; KEGG: tpp:TPASS_0654 [...]
AEC02074.1 protein networkhttps://string-db.org/network/760011.Spico_0850Extracellular solute-binding protein family 1; COGs: COG0687 Spermidine/putrescine-binding periplasmic protein; InterPro IPR006059; KEGG: tpp:TPASS_0655 spermidine/putrescine ABC transporter, per [...]
AEC02075.1 protein networkhttps://string-db.org/network/760011.Spico_0851GCN5-related N-acetyltransferase; COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: dhd:Dhaf_2686 GCN5-related N-acetyltransferase; PFAM: GCN5- [...]
AEC02076.1 protein networkhttps://string-db.org/network/760011.Spico_0852COGs: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerase 1; InterPro IPR000774:IPR001179; KEGG: dol:Dole_1577 peptidylprolyl isomerase FKBP-type; PFAM: Peptidyl-prolyl cis-trans isomerase, FKB [...]
AEC02077.1 protein networkhttps://string-db.org/network/760011.Spico_0853Conserved hypothetical protein CHP00022; COGs: COG2731 Beta-galactosidase beta subunit; InterPro IPR004375; KEGG: sea:SeAg_B4753 putative cytoplasmic protein; PFAM: Conserved hypothetical protein [...]
AEC02078.1 protein networkhttps://string-db.org/network/760011.Spico_0854KEGG: eel:EUBELI_01147 cytidylate kinase; SPTR: Putative uncharacterized protein; IMG reference gene:2503957157.
hemA protein networkhttps://string-db.org/network/760011.Spico_0855Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
AEC02080.1 protein networkhttps://string-db.org/network/760011.Spico_0856DNA-(apurinic or apyrimidinic site) lyase; COGs: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; InterPro IPR012904:IPR003265; KEGG: cac:CA_C2707 8-oxoguanine-DNA-glycosylas [...]
purL protein networkhttps://string-db.org/network/760011.Spico_0857Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent con [...]
purM protein networkhttps://string-db.org/network/760011.Spico_0858Phosphoribosylformylglycinamidine cyclo-ligase; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR000728:IPR010918:IPR004733; KEGG: ftn:FTN_0419 phosphoribosylaminoimidazol [...]
AEC02083.1 protein networkhttps://string-db.org/network/760011.Spico_0859Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion o [...]
purC protein networkhttps://string-db.org/network/760011.Spico_0860COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; HAMAP: SAICAR synthetase; InterPro IPR001636; KEGG: lpa:lpa_02418 phosphoribosylaminoimidazole-succinocarboxamide s [...]
purE protein networkhttps://string-db.org/network/760011.Spico_08611-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribon [...]
purF protein networkhttps://string-db.org/network/760011.Spico_0862Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
purN protein networkhttps://string-db.org/network/760011.Spico_0863Phosphoribosylamine--glycine ligase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinami [...]
AEC02088.1 protein networkhttps://string-db.org/network/760011.Spico_0864KEGG: nmu:Nmul_A0641 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957167.
AEC02089.1 protein networkhttps://string-db.org/network/760011.Spico_0865Endoribonuclease L-PSP; COGs: COG0251 Putative translation initiation inhibitor yjgF family; InterPro IPR006175:IPR006056; KEGG: tde:TDE2069 endoribonuclease L-PSP, putative; PFAM: Endoribonuclea [...]
AEC02090.1 protein networkhttps://string-db.org/network/760011.Spico_0866Glycosyl hydrolase family 88; COGs: COG4225 unsaturated glucuronyl hydrolase involved in regulation of surface properties and related protein; InterPro IPR010905; KEGG: ote:Oter_1360 glycosy hydr [...]
AEC02091.1 protein networkhttps://string-db.org/network/760011.Spico_0867Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: sta:STHERM_c08200 transporter; PFAM: Bind [...]
AEC02092.1 protein networkhttps://string-db.org/network/760011.Spico_0868Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: sta:STHERM_c08210 transporter; PFAM: Bi [...]
AEC02093.1 protein networkhttps://string-db.org/network/760011.Spico_0869Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: sta:STHERM_c08220 extracellular solute-binding protei [...]
trpB protein networkhttps://string-db.org/network/760011.Spico_0870Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
AEC02095.1 protein networkhttps://string-db.org/network/760011.Spico_0871Domain of unknown function DUF88; InterPro IPR021139; KEGG: vpa:VP1078 hypothetical protein; PFAM: Domain of unknown function DUF88; SPTR: Putative uncharacterized protein VP1078; IMG reference g [...]
AEC02096.1 protein networkhttps://string-db.org/network/760011.Spico_0872Hypothetical protein; KEGG: cpo:COPRO5265_1058 TM2 domain family protein; SPTR: Predicted membrane protein; IMG reference gene:2503957175; PFAM: TM2 domain.
AEC02097.1 protein networkhttps://string-db.org/network/760011.Spico_0873KEGG: brm:Bmur_1470 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957176.
AEC02098.1 protein networkhttps://string-db.org/network/760011.Spico_0874COGs: COG4260 Putative virion core protein (lumpy skin disease virus); KEGG: cce:Ccel_1422 antifreeze protein type I; SPTR: Antifreeze protein type I; IMG reference gene:2503957177; PFAM: SPFH do [...]
ackA protein networkhttps://string-db.org/network/760011.Spico_0875Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
AEC02100.1 protein networkhttps://string-db.org/network/760011.Spico_0876DJ-1 family protein; COGs: COG0693 Putative intracellular protease/amidase; InterPro IPR002818:IPR006287; KEGG: ssm:Spirs_2243 DJ-1 family protein; PFAM: ThiJ/PfpI; SPTR: Putative protease; TIGRF [...]
AEC02101.1 protein networkhttps://string-db.org/network/760011.Spico_08773-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-p [...]
AEC02102.1 protein networkhttps://string-db.org/network/760011.Spico_0878Hypothetical protein; InterPro IPR019734; KEGG: fgr:FG08956.1 hypothetical protein; SPTR: Putative ATP/GTP binding protein; IMG reference gene:2503957181.
AEC02103.1 protein networkhttps://string-db.org/network/760011.Spico_0879Amino acid/amide ABC transporter substrate-binding protein, HAAT family; COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: aoe:Cl [...]
AEC02104.1 protein networkhttps://string-db.org/network/760011.Spico_0880Amino acid/amide ABC transporter membrane protein 1, HAAT family; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: tjr:TherJR_2668 [...]
AEC02105.1 protein networkhttps://string-db.org/network/760011.Spico_0881Amino acid/amide ABC transporter membrane protein 2, HAAT family; COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: aoe:Clos_2500 inn [...]
AEC02106.1 protein networkhttps://string-db.org/network/760011.Spico_0882Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family; COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: tjr:T [...]
AEC02107.1 protein networkhttps://string-db.org/network/760011.Spico_0883Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: tjr:T [...]
AEC02108.1 protein networkhttps://string-db.org/network/760011.Spico_0884Long-chain-fatty-acid--CoA ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: ssm:Spirs_2245 AMP-dependent synthetase and ligase; PFAM: AMP-dependent sy [...]
AEC02109.1 protein networkhttps://string-db.org/network/760011.Spico_0885Beta-lactamase domain protein; COGs: COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I; InterPro IPR001279; KEGG: ssm:Spirs_2246 hypothetical protein; PFAM: Beta-lactamase-lik [...]
asnS protein networkhttps://string-db.org/network/760011.Spico_0886COGs: COG0017 Aspartyl/asparaginyl-tRNA synthetase; HAMAP: Asparaginyl-tRNA synthetase, class IIb; InterPro IPR004365:IPR004364:IPR004522; KEGG: ssm:Spirs_2248 asparaginyl-tRNA synthetase; PFAM: [...]
AEC02111.1 protein networkhttps://string-db.org/network/760011.Spico_0887Transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792; KEGG: sen:SACE_1981 protein kina [...]
AEC02112.1 protein networkhttps://string-db.org/network/760011.Spico_0888UPF0178 protein yaiI; COGs: COG1671 conserved hypothetical protein; HAMAP: Protein of unknown function DUF188; InterPro IPR003791; KEGG: mxa:MXAN_5526 YaiI/YqxD family protein; PFAM: Protein of u [...]
pfp protein networkhttps://string-db.org/network/760011.Spico_0889Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor i [...]
AEC02114.1 protein networkhttps://string-db.org/network/760011.Spico_0890Beta-mannosidase; COGs: COG3250 Beta-galactosidase/beta-glucuronidase; KEGG: ssm:Spirs_1196 beta-mannosidase; PRIAM: Beta-mannosidase; SPTR: Beta-mannosidase; IMG reference gene:2503957193; PFAM: [...]
AEC02115.1 protein networkhttps://string-db.org/network/760011.Spico_0891COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: dsy:DSY1101 hypothetical protein; PFAM: Alcohol dehydrogenase, iron-type; PRIAM: Alcohol dehydrogenase; SPTR: Putative unch [...]
AEC02116.1 protein networkhttps://string-db.org/network/760011.Spico_0892COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: dsy:DSY1102 hypothetical protein; PFAM: Aldehyde dehydrogenase domain; SPTR: Putative uncharacterized protein; IMG re [...]
AEC02117.1 protein networkhttps://string-db.org/network/760011.Spico_0893Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: ssm:Spirs_2123 extracellular solute-binding protein f [...]
AEC02118.1 protein networkhttps://string-db.org/network/760011.Spico_0894COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: ssm:Spirs_2121 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-prot [...]
AEC02119.1 protein networkhttps://string-db.org/network/760011.Spico_0895COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ssm:Spirs_2122 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-pr [...]
AEC02120.1 protein networkhttps://string-db.org/network/760011.Spico_0896ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: ssm:Spirs_1197 ROK family protein; PFAM: ROK; SPTR: Putative transcriptional regulator; IMG ref [...]
AEC02121.1 protein networkhttps://string-db.org/network/760011.Spico_0897Beta-N-acetylhexosaminidase; COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR015883; KEGG: sli:Slin_4336 beta-N-acetylhexosaminidase; PFAM: Glycoside hydrolase, family 20, catalytic core; [...]
AEC02122.1 protein networkhttps://string-db.org/network/760011.Spico_0898Protein of unknown function UPF0044; COGs: COG1534 RNA-binding protein containing KH domain possibly ribosomal protein; InterPro IPR001890; KEGG: ssm:Spirs_2265 protein of unknown function UPF004 [...]
AEC02123.1 protein networkhttps://string-db.org/network/760011.Spico_0899Long-chain-fatty-acid--CoA ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: ssm:Spirs_2267 AMP-dependent synthetase and ligase; PFAM: AMP-dependent sy [...]
AEC02124.1 protein networkhttps://string-db.org/network/760011.Spico_0900FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221:IPR004101:IPR001645; KEGG: ssm:Spirs_2271 FolC bifunctional protein; PFAM: Mur ligase, C-terminal; Mur lig [...]
AEC02125.1 protein networkhttps://string-db.org/network/760011.Spico_0901Protein of unknown function DUF814; COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616:IPR008532; KEGG: ssm:Spirs_2274 fibronectin-binding A domain protein; PFAM [...]
AEC02126.1 protein networkhttps://string-db.org/network/760011.Spico_0902KEGG: ttj:TTHA1711 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957205.
AEC02127.1 protein networkhttps://string-db.org/network/760011.Spico_0903KEGG: sta:STHERM_c03340 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957206.
miaA protein networkhttps://string-db.org/network/760011.Spico_0904tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(di [...]
AEC02129.1 protein networkhttps://string-db.org/network/760011.Spico_0905Hypothetical protein; KEGG: rrs:RoseRS_1675 dehydrogenase catalytic domain-containing protein; SPTR: Predicted protein; IMG reference gene:2503957208.
cmk-2 protein networkhttps://string-db.org/network/760011.Spico_0906COGs: COG1102 Cytidylate kinase; HAMAP: Cytidylate kinase, putative; InterPro IPR011994:IPR011892; KEGG: tde:TDE1087 cytidylate kinase; PFAM: Cytidylate kinase domain; SPTR: Cytidylate kinase; TI [...]
AEC02131.1 protein networkhttps://string-db.org/network/760011.Spico_0907Conserved hypothetical protein CHP00255; COGs: COG1561 Uncharacterized stress-induced protein; InterPro IPR013527:IPR013551:IPR005229; KEGG: sta:STHERM_c12240 protein YicC; PFAM: Domain of unknow [...]
AEC02132.1 protein networkhttps://string-db.org/network/760011.Spico_0908COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR000713:IPR013221:IPR004101; KEGG: ssm:Spirs_2282 UDP-N-acetylmuramate/alanine ligase; PFAM: Mur ligase, C-terminal; Mur ligase, cent [...]
AEC02133.1 protein networkhttps://string-db.org/network/760011.Spico_0909KEGG: pbe:PB000454.03.0 hypothetical protein; SPTR: Homoserine O-acetyltransferase; IMG reference gene:2503957212.
murE protein networkhttps://string-db.org/network/760011.Spico_0910UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-d iaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the [...]
ddl protein networkhttps://string-db.org/network/760011.Spico_0911D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
dinB protein networkhttps://string-db.org/network/760011.Spico_0912DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misa [...]
AEC02137.1 protein networkhttps://string-db.org/network/760011.Spico_0913tRNA/rRNA methyltransferase (SpoU); Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltran [...]
proC protein networkhttps://string-db.org/network/760011.Spico_0914Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
serS protein networkhttps://string-db.org/network/760011.Spico_0915seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further [...]
AEC02140.1 protein networkhttps://string-db.org/network/760011.Spico_0916Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and [...]
AEC02141.1 protein networkhttps://string-db.org/network/760011.Spico_0917Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: ssm:Spirs_2928 cell wall hydrolase/autolysin; PFAM: Cell wall hydrolase/autolysin, catal [...]
AEC02142.1 protein networkhttps://string-db.org/network/760011.Spico_0918KEGG: ssm:Spirs_2932 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957221.
proB protein networkhttps://string-db.org/network/760011.Spico_0919Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
proA protein networkhttps://string-db.org/network/760011.Spico_0920Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cycl [...]
AEC02145.1 protein networkhttps://string-db.org/network/760011.Spico_0921COGs: COG2252 Permease; InterPro IPR006043; KEGG: bpo:BP951000_1268 integral membrane transport protein; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Integral membrane transport protein; IMG r [...]
AEC02146.1 protein networkhttps://string-db.org/network/760011.Spico_0922KEGG: dps:DP1907 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957225.
AEC02147.1 protein networkhttps://string-db.org/network/760011.Spico_0923KEGG: tpv:TP04_0148 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957226.
AEC02148.1 protein networkhttps://string-db.org/network/760011.Spico_0924Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR001130:IPR015991; KEGG: ssm:Spirs_2388 hydrolase, TatD family; PFAM: Deoxyribonuclease, TatD-related; SPTR: Sec-independent p [...]
AEC02149.1 protein networkhttps://string-db.org/network/760011.Spico_0925COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771:IPR011289; KEGG: ssm:Spirs_2588 fructose-1,6-bisphosphate aldolase, class II; PFAM: Ketose-bisphosphate aldolase, class-I [...]
AEC02150.1 protein networkhttps://string-db.org/network/760011.Spico_0926NADPH-dependent FMN reductase; COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: ccb:Clocel_4239 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: Iron-s [...]
infC protein networkhttps://string-db.org/network/760011.Spico_0927Bacterial translation initiation factor 3 (bIF-3); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subu [...]
rpmI protein networkhttps://string-db.org/network/760011.Spico_0928HAMAP: Ribosomal protein L35, non-mitochondrial; InterPro IPR001706:IPR021137; KEGG: ssm:Spirs_2591 ribosomal protein L35; PFAM: Ribosomal protein L35; SPTR: 50S ribosomal protein L35; TIGRFAM: R [...]
rplT protein networkhttps://string-db.org/network/760011.Spico_0929LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing fun [...]
AEC02154.1 protein networkhttps://string-db.org/network/760011.Spico_0930KEGG: tde:TDE2153 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957234.
AEC02155.1 protein networkhttps://string-db.org/network/760011.Spico_0931InterPro IPR001440:IPR019734; KEGG: ssm:Spirs_2596 tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide TPR-1; SPTR: TPR domain protein; IMG reference gene:2503957235.
AEC02156.1 protein networkhttps://string-db.org/network/760011.Spico_0932Uncharacterized protein family UPF0079, ATPase; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: tde:TDE1469 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase ba [...]
AEC02157.1 protein networkhttps://string-db.org/network/760011.Spico_0933Universal protein YeaZ; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905:IPR022496; KEGG: ssm:Spirs_2605 peptidase M22 glycoprotease; PF [...]
AEC02158.1 protein networkhttps://string-db.org/network/760011.Spico_0934COGs: COG0492 Thioredoxin reductase; InterPro IPR013027:IPR005982; KEGG: ssm:Spirs_2612 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Thioredoxi [...]
glgA protein networkhttps://string-db.org/network/760011.Spico_0935Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
AEC02160.1 protein networkhttps://string-db.org/network/760011.Spico_0936Glucose-1-phosphate adenylyltransferase; COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR005835; KEGG: ssm:Spirs_2619 nucleotidyl transferase; PFAM: Nucleotidyl transferase; PRIAM: Gluco [...]
AEC02161.1 protein networkhttps://string-db.org/network/760011.Spico_0937KEGG: ssm:Spirs_2621 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957241.
nnrD protein networkhttps://string-db.org/network/760011.Spico_0938YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converte [...]
AEC02163.1 protein networkhttps://string-db.org/network/760011.Spico_0939Helix-turn-helix domain protein; InterPro IPR001387; KEGG: dae:Dtox_2429 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Transcriptiona [...]
AEC02164.1 protein networkhttps://string-db.org/network/760011.Spico_0940ABC transporter, periplasmic binding protein, thiB subfamily; COGs: COG4143 ABC-type thiamine transport system periplasmic component; InterPro IPR006059:IPR005948; KEGG: ssm:Spirs_1695 ABC transp [...]
AEC02165.1 protein networkhttps://string-db.org/network/760011.Spico_0941COGs: COG1178 ABC-type Fe3+ transport system permease component; InterPro IPR000515; KEGG: ssm:Spirs_1694 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-prote [...]
AEC02166.1 protein networkhttps://string-db.org/network/760011.Spico_0942Fe(3+)-transporting ATPase; COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003439:IPR003593; KEGG: hut:Huta_0390 ABC transporter related; PFAM: ABC [...]
uvrB protein networkhttps://string-db.org/network/760011.Spico_0943Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abn [...]
AEC02168.1 protein networkhttps://string-db.org/network/760011.Spico_0944DegP2 peptidase; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001254:IPR001478; KEGG: ssm:Spirs_2332 peptidase S1 and S6 chymotrypsi [...]
AEC02169.1 protein networkhttps://string-db.org/network/760011.Spico_0945ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Be [...]
AEC02170.1 protein networkhttps://string-db.org/network/760011.Spico_0946Fructokinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: msv:Mesil_1102 PfkB domain protein; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: PfkB domain [...]
AEC02171.1 protein networkhttps://string-db.org/network/760011.Spico_0947Metal dependent phosphohydrolase; COGs: COG3294 conserved hypothetical protein; InterPro IPR006674:IPR003607; KEGG: ssm:Spirs_0575 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphoh [...]
glnS protein networkhttps://string-db.org/network/760011.Spico_0948COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; HAMAP: Glutaminyl-tRNA synthetase, bacterial; InterPro IPR022861:IPR020058:IPR020059:IPR004514; KEGG: ssm:Spirs_1481 glutaminyl-tRNA synthe [...]
AEC02173.1 protein networkhttps://string-db.org/network/760011.Spico_0949Listeria/Bacterioides repeat-containing protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378:IPR000408:IPR011110; KEGG: aeh:Mlg_2687 regu [...]
AEC02174.1 protein networkhttps://string-db.org/network/760011.Spico_0950Regulatory protein LuxR; InterPro IPR000792; KEGG: rle:RL0075 GerE family transcriptional regulator; PFAM: Transcription regulator LuxR, C-terminal; SMART: Transcription regulator LuxR, C-termina [...]
AEC02175.1 protein networkhttps://string-db.org/network/760011.Spico_0951Rubrerythrin; COGs: COG1592 Rubrerythrin; InterPro IPR003251; KEGG: cpy:Cphy_0524 rubrerythrin; PFAM: Rubrerythrin; SPTR: Rubrerythrin; IMG reference gene:2503957255; PFAM: Rubrerythrin.
AEC02176.1 protein networkhttps://string-db.org/network/760011.Spico_0952Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: eel:EUBELI_20027 Fur family transcriptional regulator, ferric uptake regulator; P [...]
AEC02177.1 protein networkhttps://string-db.org/network/760011.Spico_0953COGs: COG1092 SAM-dependent methyltransferase; KEGG: ssm:Spirs_1479 rRNA (guanine-N(2)-)-methyltransferase; PRIAM: rRNA (guanine-N(2)-)-methyltransferase; SPTR: Ribosomal RNA large subunit methyl [...]
AEC02178.1 protein networkhttps://string-db.org/network/760011.Spico_0954Transposase IS4 family protein; COGs: COG5421 Transposase; InterPro IPR002559; KEGG: cob:COB47_1677 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family prote [...]
AEC02179.1 protein networkhttps://string-db.org/network/760011.Spico_0955KEGG: ssm:Spirs_1477 hypothetical protein; SPTR: Predicted protein; IMG reference gene:2503957259.
AEC02180.1 protein networkhttps://string-db.org/network/760011.Spico_0956Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845:IPR005846:IPR005843; KEGG: ssm:Spirs_1476 phosphoglucomutase/phosph [...]
AEC02181.1 protein networkhttps://string-db.org/network/760011.Spico_0957COGs: COG1087 UDP-glucose 4-epimerase; InterPro IPR001509:IPR005886; KEGG: plt:Plut_0420 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: UDP-glucose 4-epimerase; SPTR: [...]
AEC02182.1 protein networkhttps://string-db.org/network/760011.Spico_0958Iron dependent repressor, N-terminal protein; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR022687:IPR022689; KEGG: apv:Apar_1294 iron (metal) dependent repressor, Dtx [...]
AEC02183.1 protein networkhttps://string-db.org/network/760011.Spico_0959FeoA family protein; InterPro IPR007167; KEGG: cbt:CLH_2780 hypothetical protein; PFAM: Ferrous iron transporter, FeoA subunit; SMART: Ferrous iron transporter, FeoA subunit; SPTR: Conserved doma [...]
AEC02184.1 protein networkhttps://string-db.org/network/760011.Spico_0960FeoA family protein; COGs: COG1918 Fe2+ transport system protein A; InterPro IPR007167; KEGG: eel:EUBELI_00573 ferrous iron transport protein A; PFAM: Ferrous iron transporter, FeoA subunit; SMAR [...]
AEC02185.1 protein networkhttps://string-db.org/network/760011.Spico_0961Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) [...]
AEC02186.1 protein networkhttps://string-db.org/network/760011.Spico_0962KEGG: fma:FMG_1212 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957266.
AEC02187.1 protein networkhttps://string-db.org/network/760011.Spico_0963NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: cbi:CLJ_B0889 flavodoxin-like fold domain protein; PFAM: [...]
AEC02188.1 protein networkhttps://string-db.org/network/760011.Spico_0964COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: ppy:PPE_01086 5'-nucleotidase/2',3'-cyclic phosphodiesterase; PFAM: 5'-Nucle [...]
AEC02189.1 protein networkhttps://string-db.org/network/760011.Spico_0965KEGG: ssm:Spirs_2236 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957270.
AEC02190.1 protein networkhttps://string-db.org/network/760011.Spico_0966UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
udk protein networkhttps://string-db.org/network/760011.Spico_0967COGs: COG0572 Uridine kinase; HAMAP: Uridine kinase; InterPro IPR000764:IPR006083; KEGG: ssm:Spirs_2239 uridine kinase; PFAM: Phosphoribulokinase/uridine kinase; SPTR: Uridine kinase; TIGRFAM: Ur [...]
AEC02192.1 protein networkhttps://string-db.org/network/760011.Spico_0968Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
lepA protein networkhttps://string-db.org/network/760011.Spico_0969GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codo [...]
ftsH protein networkhttps://string-db.org/network/760011.Spico_0970Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral mem [...]
tilS protein networkhttps://string-db.org/network/760011.Spico_0971tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is c [...]
AEC02196.1 protein networkhttps://string-db.org/network/760011.Spico_0972COGs: COG0193 Peptidyl-tRNA hydrolase; InterPro IPR001328; KEGG: ssm:Spirs_1815 peptidyl-tRNA hydrolase; PFAM: Peptidyl-tRNA hydrolase; PRIAM: Aminoacyl-tRNA hydrolase; SPTR: Peptidyl-tRNA hydrol [...]
rplY protein networkhttps://string-db.org/network/760011.Spico_097350S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 fa [...]
AEC02198.1 protein networkhttps://string-db.org/network/760011.Spico_0974COGs: COG2768 Uncharacterized Fe-S center protein; KEGG: afn:Acfer_0536 uncharacterized Fe-S center protein; SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:250395727 [...]
spoVG protein networkhttps://string-db.org/network/760011.Spico_0975Septation protein spoVG; Could be involved in septation.
ispE protein networkhttps://string-db.org/network/760011.Spico_09764-diphosphocytidyl-2-C-methyl-D- erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
AEC02201.1 protein networkhttps://string-db.org/network/760011.Spico_0977InterPro IPR005122; KEGG: azo:azo3976 uracil-DNA glycosylase; PFAM: Uracil-DNA glycosylase-like; SPTR: Probable uracil-DNA glycosylase; IMG reference gene:2503957283; PFAM: Uracil DNA glycosylase [...]
AEC02202.1 protein networkhttps://string-db.org/network/760011.Spico_0978Long-chain-fatty-acid--CoA ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: ssm:Spirs_3134 AMP-dependent synthetase and ligase; PFAM: AMP-dependent sy [...]
AEC02203.1 protein networkhttps://string-db.org/network/760011.Spico_0979COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: ssm:Spirs_1424 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; S [...]
tyrS protein networkhttps://string-db.org/network/760011.Spico_0980tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
glyQS protein networkhttps://string-db.org/network/760011.Spico_0981glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
gltX protein networkhttps://string-db.org/network/760011.Spico_0982glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end [...]
AEC02207.1 protein networkhttps://string-db.org/network/760011.Spico_0983Hypothetical protein; COGs: COG1647 Esterase/lipase; KEGG: pmo:Pmob_0119 carboxylesterase, putative; SPTR: Carboxylesterase, putative; IMG reference gene:2503957289.
AEC02208.1 protein networkhttps://string-db.org/network/760011.Spico_0984Transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792; KEGG: bpo:BP951000_1223 two-comp [...]
AEC02209.1 protein networkhttps://string-db.org/network/760011.Spico_0985Hypothetical protein; KEGG: lsp:Bsph_1275 abortive phage resistance protein, putative; SPTR: Abortive phage resistance protein, putative; IMG reference gene:2503957291.
AEC02210.1 protein networkhttps://string-db.org/network/760011.Spico_0986KEGG: cyh:Cyan8802_0995 RloA protein; SPTR: RloA protein; IMG reference gene:2503957292.
AEC02211.1 protein networkhttps://string-db.org/network/760011.Spico_0987KEGG: ssm:Spirs_0126 hypothetical protein; SPTR: Vacuolar protein sorting-associated protein 13 family protein; IMG reference gene:2503957293.
AEC02212.1 protein networkhttps://string-db.org/network/760011.Spico_0988ATPase; KEGG: bwe:BcerKBAB4_5427 ATPase; SPTR: Aspartic acid-rich protein aspolin2-2; IMG reference gene:2503957294.
AEC02213.1 protein networkhttps://string-db.org/network/760011.Spico_0989Listeria/Bacterioides repeat-containing protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378; KEGG: aeh:Mlg_2687 regulator of chromosome [...]
AEC02214.1 protein networkhttps://string-db.org/network/760011.Spico_0991ABC transporter substrate binding protein; COGs: COG2984 ABC-type uncharacterized transport system periplasmic component; InterPro IPR007487; KEGG: gem:GM21_0736 protein of unknown function DUF53 [...]
AEC02215.1 protein networkhttps://string-db.org/network/760011.Spico_0992ABC transporter substrate binding protein; COGs: COG2984 ABC-type uncharacterized transport system periplasmic component; InterPro IPR007487; KEGG: dat:HRM2_37760 ABC-type transporter, periplasmi [...]
AEC02216.1 protein networkhttps://string-db.org/network/760011.Spico_0993ABC transporter substrate binding protein; COGs: COG2984 ABC-type uncharacterized transport system periplasmic component; InterPro IPR007487; KEGG: gsu:GSU0210 hypothetical protein; PFAM: ABC tra [...]
AEC02217.1 protein networkhttps://string-db.org/network/760011.Spico_0994Inner-membrane translocator; COGs: COG4120 ABC-type uncharacterized transport system permease component; InterPro IPR001851; KEGG: dat:HRM2_37770 ABC-type transporter, permease component; PFAM: A [...]
AEC02218.1 protein networkhttps://string-db.org/network/760011.Spico_0995COGs: COG1101 ABC-type uncharacterized transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: gbm:Gbem_0725 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; PRIAM: [...]
AEC02219.1 protein networkhttps://string-db.org/network/760011.Spico_0996MATE efflux family protein; COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: cpy:Cphy_1252 MATE efflux family protein; PFAM: Multi antimicrobial extrusion protein; SPTR: [...]
rsfS protein networkhttps://string-db.org/network/760011.Spico_0997Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S r [...]
AEC02221.1 protein networkhttps://string-db.org/network/760011.Spico_0998Hypothetical protein; KEGG: cpi:Cpin_5296 beta-ketoacyl synthase; SPTR: Central motor kinesin 1; IMG reference gene:2503957304.
AEC02222.1 protein networkhttps://string-db.org/network/760011.Spico_0999Metal dependent phosphohydrolase; COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; InterPro IPR006674; KEGG: rxy:Rxyl_2559 metal dependent phosphohydrolase; PFAM: Metal-dependen [...]
nadD protein networkhttps://string-db.org/network/760011.Spico_1000Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
obg protein networkhttps://string-db.org/network/760011.Spico_1001GTPase obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in contro [...]
rpmA protein networkhttps://string-db.org/network/760011.Spico_1002COGs: COG0211 Ribosomal protein L27; HAMAP: Ribosomal protein L27; InterPro IPR001684; KEGG: sta:STHERM_c10280 50S ribosomal protein L27; PFAM: Ribosomal protein L27; SPTR: 50S ribosomal protein [...]
rplU protein networkhttps://string-db.org/network/760011.Spico_100350S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
AEC02227.1 protein networkhttps://string-db.org/network/760011.Spico_1004Regulatory protein TetR; InterPro IPR001647; KEGG: mpd:MCP_0597 TetR family transcriptional regulator; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcripti [...]
argS protein networkhttps://string-db.org/network/760011.Spico_1005COGs: COG0018 Arginyl-tRNA synthetase; HAMAP: Arginyl-tRNA synthetase, class Ic; InterPro IPR001278:IPR005148:IPR015945:IPR008909; KEGG: ssm:Spirs_1801 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA [...]
birA protein networkhttps://string-db.org/network/760011.Spico_1006biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
AEC02230.1 protein networkhttps://string-db.org/network/760011.Spico_1007BioY protein; COGs: COG1268 conserved hypothetical protein; InterPro IPR003784; KEGG: sta:STHERM_c14470 biotin synthesis protein BioY; PFAM: BioY protein; SPTR: Biotin synthesis protein BioY; IMG [...]
AEC02231.1 protein networkhttps://string-db.org/network/760011.Spico_1008COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: ssm:Spirs_1684 serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide repeat; PRIAM: Serine O-acetyltransferase; SPT [...]
AEC02232.1 protein networkhttps://string-db.org/network/760011.Spico_1009MiaB-like tRNA modifying enzyme; COGs: COG0621 2-methylthioadenine synthetase; InterProIPR013848:IPR007197:IPR005839:IPR006467:IPR 006638; KEGG: ssm:Spirs_1516 MiaB-like tRNA modifying enzyme; PF [...]
AEC02233.1 protein networkhttps://string-db.org/network/760011.Spico_1010COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: ssm:Spirs_1513 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: Arogenate dehydrogenase 2; IMG reference gene:2503 [...]
AEC02234.1 protein networkhttps://string-db.org/network/760011.Spico_1011COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR004614; KEGG: ssm:Spirs_1512 phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; PRIAM: Phosphate acetyltransferase [...]
AEC02235.1 protein networkhttps://string-db.org/network/760011.Spico_1012MATE efflux family protein; COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: cac:CA_C3444 cation efflux pump (multidrug resistance protein); PFAM: Multi antimicrobial ext [...]
rsmA protein networkhttps://string-db.org/network/760011.Spico_1013Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S part [...]
AEC02238.1 protein networkhttps://string-db.org/network/760011.Spico_1016KEGG: ssm:Spirs_1495 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957322.
AEC02239.1 protein networkhttps://string-db.org/network/760011.Spico_1017Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845; KEGG: sta:STHERM_c11950 hypothetical protein; PFAM: Alpha-D-phosph [...]
AEC02240.1 protein networkhttps://string-db.org/network/760011.Spico_1018COGs: COG0546 phosphatase; InterPro IPR005834; KEGG: apv:Apar_0414 HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase; PRIAM: Phosphoglycolate phosphat [...]
AEC02241.1 protein networkhttps://string-db.org/network/760011.Spico_1019PUA domain containing protein; COGs: COG1092 SAM-dependent methyltransferase; KEGG: phe:Phep_4225 PUA domain containing protein; SPTR: PUA domain containing protein; IMG reference gene:2503957325 [...]
AEC02242.1 protein networkhttps://string-db.org/network/760011.Spico_1020Protein of unknown function UPF0153; InterPro IPR005358; KEGG: tde:TDE0847 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: Putative uncharacterized protein; IMG referenc [...]
AEC02243.1 protein networkhttps://string-db.org/network/760011.Spico_1021Mg2 transporter protein CorA family protein; COGs: COG0598 Mg2+ and Co2+ transporter; InterPro IPR002523; KEGG: cce:Ccel_2001 Mg2 transporter protein CorA family protein; PFAM: Mg2+ transporter p [...]
AEC02244.1 protein networkhttps://string-db.org/network/760011.Spico_1022Metal dependent phosphohydrolase; COGs: COG2316 hydrolase (HD superfamily); InterPro IPR006674:IPR006675; KEGG: ttm:Tthe_2220 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrol [...]
AEC02245.1 protein networkhttps://string-db.org/network/760011.Spico_1023Hypothetical protein; KEGG: hmg:100201846 similar to predicted protein; IMG reference gene:2503957329.
AEC02246.1 protein networkhttps://string-db.org/network/760011.Spico_1024Hypothetical protein; IMG reference gene:2503957330.
AEC02247.1 protein networkhttps://string-db.org/network/760011.Spico_1025Dihydroorotase, putative; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; KEGG: tde:TDE2107 dihydroorotase, putative; SPTR: Dihydroorotase, putative; IMG reference gene:2503957331 [...]
AEC02248.1 protein networkhttps://string-db.org/network/760011.Spico_1026COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR012135:IPR008333:IPR001433:IPR005720; KEGG: tde:TDE0982 dihydroorotate dehydrogenase/oxidoreductase, FAD-binding; PFAM: Dihydroorotate dehy [...]
AEC02249.1 protein networkhttps://string-db.org/network/760011.Spico_1027COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR001754:IPR011995; KEGG: ssm:Spirs_1435 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase domain; PRI [...]
pyrE protein networkhttps://string-db.org/network/760011.Spico_1028Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
AEC02251.1 protein networkhttps://string-db.org/network/760011.Spico_1029COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR006132:IPR006131:IPR002082; KEGG: tde:TDE0129 bifunctional aspartate carbamoyltransferase catalytic subunit/aspartate car [...]
AEC02252.1 protein networkhttps://string-db.org/network/760011.Spico_1030ybaK/ebsC protein; COGs: COG2606 conserved hypothetical protein; InterPro IPR007214:IPR004369; KEGG: ssm:Spirs_3308 YbaK/EbsC protein; PFAM: YbaK/aminoacyl-tRNA synthetase-associated domain; SPTR [...]
AEC02253.1 protein networkhttps://string-db.org/network/760011.Spico_1031HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG0546 phosphatase; InterPro IPR005834:IPR006439; KEGG: rha:RHA1_ro01185 phosphoglycolate phosphatase; PFAM: Haloacid dehalogenase-like [...]
AEC02254.1 protein networkhttps://string-db.org/network/760011.Spico_1033Hypothetical protein; KEGG: ank:AnaeK_1538 sec-C motif domain protein; SPTR: SEC-C motif domain protein; IMG reference gene:2503957339.
AEC02255.1 protein networkhttps://string-db.org/network/760011.Spico_1034Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein; COGs: COG3467 flavin-nucleotide-binding protein; InterPro IPR011576; KEGG: ctc:CTC00899 5-nitroimidazole antibiotic resistance prote [...]
AEC02256.1 protein networkhttps://string-db.org/network/760011.Spico_1035Radical SAM domain protein; COGs: COG4277 DNA-binding protein with the Helix-hairpin-helix motif; InterPro IPR007197; KEGG: tjr:TherJR_1012 radical SAM domain protein; PFAM: Radical SAM; SPTR: He [...]
AEC02257.1 protein networkhttps://string-db.org/network/760011.Spico_1036Protein of unknown function UPF0047; COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: chy:CHY_0024 hypothetical protein; PFAM: Uncharacterised protein family UPF0047; SPTR: [...]
AEC02258.1 protein networkhttps://string-db.org/network/760011.Spico_1037Inner-membrane translocator; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: gka:GK1893 sugar ABC transporter (permease [...]
AEC02259.1 protein networkhttps://string-db.org/network/760011.Spico_1038Monosaccharide ABC transporter ATP-binding protein, CUT2 family; COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: str:Sterm_4010 ABC transporter [...]
AEC02260.1 protein networkhttps://string-db.org/network/760011.Spico_1039Sugar ABC transporter (sugar-binding protein); COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: gka:GK1896 sugar ABC transporter (sugar-binding protein); SPTR: Periplasm [...]
AEC02261.1 protein networkhttps://string-db.org/network/760011.Spico_1040NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: rca:Rcas_0181 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimera [...]
AEC02262.1 protein networkhttps://string-db.org/network/760011.Spico_1041GntR domain protein; COGs: COG2186 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: rxy:Rxyl_0539 GntR family transcriptional regulator; PFAM: GntR, C-terminal; HTH transcriptional [...]
AEC02263.1 protein networkhttps://string-db.org/network/760011.Spico_10423-oxoacyl-(acyl-carrier-protein) reductase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: pjd:Pjdr2_0308 short [...]
AEC02264.1 protein networkhttps://string-db.org/network/760011.Spico_1043Protein of unknown function DUF849; COGs: COG3246 conserved hypothetical protein; InterPro IPR008567; KEGG: sth:STH64 hypothetical protein; PFAM: Protein of unknown function DUF849, prokaryotic; [...]
AEC02265.1 protein networkhttps://string-db.org/network/760011.Spico_1044Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104:IPR000587:IPR000994; KEGG: csh:Closa_3838 oxidoreductase domain protein; PFAM: Oxidore [...]
AEC02266.1 protein networkhttps://string-db.org/network/760011.Spico_1045COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: aco:Amico_0368 aminotransferase class I and II; PFAM: Aminotransferase, class I/classII; PRIAM: Aspartate tra [...]
AEC02267.1 protein networkhttps://string-db.org/network/760011.Spico_1046Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836:IPR005946; KEGG: ssm:Spirs_0557 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribos [...]
AEC02268.1 protein networkhttps://string-db.org/network/760011.Spico_1047COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: thx:Thet_2162 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-prote [...]
AEC02269.1 protein networkhttps://string-db.org/network/760011.Spico_1048COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: tle:Tlet_1227 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-pro [...]
AEC02270.1 protein networkhttps://string-db.org/network/760011.Spico_1049Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: tpd:Teth39_0261 extracellular solute-binding protein; [...]
AEC02271.1 protein networkhttps://string-db.org/network/760011.Spico_1050Cyclomaltodextrinase; COGs: COG0366 Glycosidase; InterPro IPR004185:IPR006047:IPR006589; KEGG: bse:Bsel_1069 alpha amylase catalytic region; PFAM: Glycosyl hydrolase, family 13, catalytic domain; [...]
AEC02272.1 protein networkhttps://string-db.org/network/760011.Spico_1051Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: afl:Aflv_2186 transcriptional regulator, LacI family (HTH and periplasmic-bin [...]
AEC02273.1 protein networkhttps://string-db.org/network/760011.Spico_1052COGs: COG0165 Argininosuccinate lyase; InterPro IPR022761:IPR009049; KEGG: ssm:Spirs_3701 argininosuccinate lyase; PFAM: Lyase 1, N-terminal; PRIAM: Argininosuccinate lyase; SPTR: Argininosuccina [...]
AEC02274.1 protein networkhttps://string-db.org/network/760011.Spico_1053KEGG: sta:STHERM_c01870 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957359.
AEC02275.1 protein networkhttps://string-db.org/network/760011.Spico_1054Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766:IPR005746; KEGG: sta:STHERM_c01860 thioredoxin; PFAM: Thioredoxin domain; SPTR: Thioredoxin; TIGRFAM: Thioredo [...]
AEC02276.1 protein networkhttps://string-db.org/network/760011.Spico_1055COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: ssm:Spirs_3718 single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-s [...]
AEC02277.1 protein networkhttps://string-db.org/network/760011.Spico_1056Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
AEC02278.1 protein networkhttps://string-db.org/network/760011.Spico_1057Radical SAM domain protein; COGs: COG1313 Uncharacterized Fe-S protein PflX homolog of pyruvate formate lyase activating protein; InterPro IPR007197; KEGG: ssm:Spirs_3763 radical SAM domain prote [...]
AEC02279.1 protein networkhttps://string-db.org/network/760011.Spico_1058Patatin; COGs: COG3621 Patatin; InterPro IPR002641; KEGG: ssm:Spirs_0041 patatin; PFAM: Patatin/Phospholipase A2-related; SPTR: Patatin family protein; IMG reference gene:2503957364; PFAM: Patati [...]
AEC02280.1 protein networkhttps://string-db.org/network/760011.Spico_1059Phosphomethylpyrimidine kinase type-1; COGs: COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; InterPro IPR013749; KEGG: hor:Hore_04110 pyridoxamine kinase; PFAM: Phosphomethylpyrimidine kinase t [...]
AEC02281.1 protein networkhttps://string-db.org/network/760011.Spico_1060COGs: COG1109 Phosphomannomutase; InterPro IPR005844; KEGG: ssm:Spirs_2289 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domai [...]
AEC02282.1 protein networkhttps://string-db.org/network/760011.Spico_1061Hexokinase; COGs: COG5026 Hexokinase; InterPro IPR022672:IPR022673; KEGG: ssm:Spirs_3985 hexokinase; PFAM: Hexokinase, C-terminal; Hexokinase, N-terminal; PRIAM: Hexokinase; SPTR: Putative unchar [...]
AEC02283.1 protein networkhttps://string-db.org/network/760011.Spico_1062COGs: COG2925 Exonuclease I; InterPro IPR013520:IPR013620:IPR006055; KEGG: ssm:Spirs_3051 exodeoxyribonuclease I; PFAM: Exonuclease C-terminal; Exonuclease, RNase T/DNA polymerase III; PRIAM: Exo [...]
AEC02284.1 protein networkhttps://string-db.org/network/760011.Spico_1063Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR011110:IPR000408; KEGG: aeh:Mlg_2687 regulator of chromos [...]
kbl protein networkhttps://string-db.org/network/760011.Spico_10642-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
AEC02286.1 protein networkhttps://string-db.org/network/760011.Spico_1065L-threonine 3-dehydrogenase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: bmd:BMD_1541 NAD dependent epimerase/dehydratase family protein; PFAM: NAD-dependent e [...]
AEC02287.1 protein networkhttps://string-db.org/network/760011.Spico_1066Helix-turn-helix domain protein; InterPro IPR001387:IPR013096; KEGG: ssm:Spirs_2303 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-t [...]
AEC02288.1 protein networkhttps://string-db.org/network/760011.Spico_1067Major facilitator superfamily MFS_1; COGs: COG2211 Na+/melibiose symporter and related transporter; InterPro IPR011701; KEGG: tth:TT_P0219 hypothetical protein; PFAM: Major facilitator superfamil [...]
AEC02289.1 protein networkhttps://string-db.org/network/760011.Spico_1068COGs: COG3345 Alpha-galactosidase; InterPro IPR000111; KEGG: ere:EUBREC_0489 alpha-galactosidase; PFAM: Glycoside hydrolase, clan GH-D; PRIAM: Alpha-galactosidase; SPTR: Putative uncharacterized [...]
AEC02290.1 protein networkhttps://string-db.org/network/760011.Spico_1069Glycoside hydrolase 97; InterPro IPR019563; KEGG: hje:HacjB3_16901 glycoside hydrolase 97; PFAM: Glycoside hydrolase, family 97; SPTR: Alpha-glucosidase; IMG reference gene:2503957375; PFAM: Glyc [...]
AEC02291.1 protein networkhttps://string-db.org/network/760011.Spico_1070COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: cce:Ccel_1254 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-prote [...]
AEC02292.1 protein networkhttps://string-db.org/network/760011.Spico_1071Binding-protein-dependent transport systems inner membrane component; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_4465 binding- [...]
AEC02293.1 protein networkhttps://string-db.org/network/760011.Spico_1072Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: cce:Ccel_1252 extracellular solute-binding protein fa [...]
AEC02294.1 protein networkhttps://string-db.org/network/760011.Spico_1073Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: ppp:PHYPADRAFT_103760 hypothetical protein; PFAM: HTH tr [...]
prfA protein networkhttps://string-db.org/network/760011.Spico_1074Bacterial peptide chain release factor 1 (bRF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
prmC protein networkhttps://string-db.org/network/760011.Spico_1075protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally [...]
AEC02297.1 protein networkhttps://string-db.org/network/760011.Spico_1076(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in respo [...]
AEC02298.1 protein networkhttps://string-db.org/network/760011.Spico_1077COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500; KEGG: ssm:Spirs_2662 sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosp [...]
AEC02299.1 protein networkhttps://string-db.org/network/760011.Spico_1078Hypothetical protein; KEGG: asc:ASAC_1319 dehydrogenase; SPTR: Aquaporin Z; manually curated; IMG reference gene:2503957384.
AEC02300.1 protein networkhttps://string-db.org/network/760011.Spico_1079Hypothetical protein; KEGG: ppp:PHYPADRAFT_84532 Rb -related protein; SPTR: Retinoblastoma-related protein; IMG reference gene:2503957385.
AEC02301.1 protein networkhttps://string-db.org/network/760011.Spico_1080Phospholipase D/Transphosphatidylase; COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: dal:Dalk_3445 phospholipase D/transphosphatidy [...]
AEC02302.1 protein networkhttps://string-db.org/network/760011.Spico_1081COGs: COG0295 Cytidine deaminase; InterPro IPR005834:IPR002125:IPR006402:IPR006262; KEGG: ssm:Spirs_2666 cytidine deaminase; PFAM: Haloacid dehalogenase-like hydrolase; CMP/dCMP deaminase, zinc-b [...]
glyA protein networkhttps://string-db.org/network/760011.Spico_1082Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
infA protein networkhttps://string-db.org/network/760011.Spico_1083Bacterial translation initiation factor 1 (bIF-1); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-f [...]
AEC02305.1 protein networkhttps://string-db.org/network/760011.Spico_1084KEGG: scm:SCHCODRAFT_61185 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957390.
AEC02306.1 protein networkhttps://string-db.org/network/760011.Spico_10852-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
AEC02307.1 protein networkhttps://string-db.org/network/760011.Spico_1086Smr protein/MutS2; COGs: COG2840 conserved hypothetical protein; InterPro IPR002625; KEGG: tde:TDE1254 Smr domain-containing protein; PFAM: Smr protein/MutS2 C-terminal; SMART: Smr protein/MutS2 [...]
AEC02308.1 protein networkhttps://string-db.org/network/760011.Spico_1087COGs: COG3448 CBS-domain-containing membrane protein; InterPro IPR000644:IPR002912; KEGG: ssm:Spirs_0348 putative signal transduction protein with CBS domains; PFAM: Cystathionine beta-synthase, [...]
AEC02309.1 protein networkhttps://string-db.org/network/760011.Spico_1088Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: ssm:S [...]
AEC02310.1 protein networkhttps://string-db.org/network/760011.Spico_1089Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family; COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: ddf:D [...]
AEC02311.1 protein networkhttps://string-db.org/network/760011.Spico_1090Inner-membrane translocator; COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: dvl:Dvul_2395 inner-membrane translocator; PFAM: ABC t [...]
AEC02312.1 protein networkhttps://string-db.org/network/760011.Spico_1091Amino acid/amide ABC transporter membrane protein 1, HAAT family; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: smc:SmuNN2025_04 [...]
AEC02313.1 protein networkhttps://string-db.org/network/760011.Spico_1092Extracellular ligand-binding receptor; COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: dtu:Dtur_0932 extracellular ligand-bindi [...]
AEC02314.1 protein networkhttps://string-db.org/network/760011.Spico_1093COGs: COG3541 nucleotidyltransferase; InterPro IPR018775; KEGG: lic:LIC12213 hypothetical protein; PFAM: Nucleotidyltransferase, predicted; SPTR: Putative uncharacterized protein; IMG reference g [...]
AEC02315.1 protein networkhttps://string-db.org/network/760011.Spico_1094COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: spv:SPH_1818 nitroreductase family protein; PFAM: Nitroreductase-like; SPTR: Nitroreductase; IMG reference gene:2503957401; PFAM: Nitroredu [...]
AEC02316.1 protein networkhttps://string-db.org/network/760011.Spico_1095Hypothetical protein; KEGG: rno:361605 PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae); SPTR: Putative uncharacterized protein; IMG reference gene:2503957402.
topA protein networkhttps://string-db.org/network/760011.Spico_1096DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of [...]
AEC02318.1 protein networkhttps://string-db.org/network/760011.Spico_1097KEGG: ssm:Spirs_3916 hypothetical protein; SPTR: Extracellular solute-binding protein family 5; IMG reference gene:2503957404.
ychF protein networkhttps://string-db.org/network/760011.Spico_1098GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
hflX protein networkhttps://string-db.org/network/760011.Spico_1099GTP-binding proten HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPas [...]
AEC02321.1 protein networkhttps://string-db.org/network/760011.Spico_1100KEGG: pmo:Pmob_1807 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957407.
AEC02322.1 protein networkhttps://string-db.org/network/760011.Spico_1101COGs: COG1297 membrane protein; InterPro IPR004813; KEGG: cce:Ccel_0706 oligopeptide transporters, OPT superfamily; PFAM: Oligopeptide transporter OPT superfamily; SPTR: Oligopeptide transporter, [...]
AEC02323.1 protein networkhttps://string-db.org/network/760011.Spico_1102Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
alaS protein networkhttps://string-db.org/network/760011.Spico_1103alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
AEC02325.1 protein networkhttps://string-db.org/network/760011.Spico_1104SMF family protein; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: kko:Kkor_2616 DNA protecting protein DprA; PFAM: DNA recombination-med [...]
AEC02326.1 protein networkhttps://string-db.org/network/760011.Spico_1105COGs: COG1335 Amidase related to nicotinamidase; KEGG: ele:Elen_0388 conserved hypothetical protein, putative amidase; SPTR: Putative uncharacterized protein; IMG reference gene:2503957413; PFAM: [...]
AEC02327.1 protein networkhttps://string-db.org/network/760011.Spico_1106Ribosylpyrimidine nucleosidase; COGs: COG1957 Inosine-uridine nucleoside N-ribohydrolase; InterPro IPR001910; KEGG: str:Sterm_3734 ribosylpyrimidine nucleosidase; PFAM: Inosine/uridine-preferring [...]
AEC02328.1 protein networkhttps://string-db.org/network/760011.Spico_1107COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: sdl:Sdel_1154 nitroreductase; PFAM: Nitroreductase-like; SPTR: Nitroreductase; IMG reference gene:2503957415; PFAM: Nitroreductase family.
AEC02329.1 protein networkhttps://string-db.org/network/760011.Spico_1108COGs: COG0813 Purine-nucleoside phosphorylase; InterPro IPR000845; KEGG: csh:Closa_1682 purine nucleoside phosphorylase; PFAM: Nucleoside phosphorylase domain; PRIAM: Purine-nucleoside phosphoryl [...]
AEC02330.1 protein networkhttps://string-db.org/network/760011.Spico_1109Nucleoside ABC transporter membrane protein; COGs: COG1079 ABC-type transport system permease component; InterPro IPR001851; KEGG: amt:Amet_3583 inner-membrane translocator; PFAM: ABC transporter [...]
AEC02331.1 protein networkhttps://string-db.org/network/760011.Spico_1110Inner-membrane translocator; COGs: COG4603 ABC-type uncharacterized transport system permease component; InterPro IPR001851; KEGG: sta:STHERM_c17730 putative permease; PFAM: ABC transporter perme [...]
AEC02332.1 protein networkhttps://string-db.org/network/760011.Spico_1111Nucleoside ABC transporter ATP-binding protein; COGs: COG3845 ABC-type uncharacterized transport systems ATPase components; InterPro IPR003439:IPR003593; KEGG: aoe:Clos_0964 ABC transporter relat [...]
AEC02333.1 protein networkhttps://string-db.org/network/760011.Spico_1112Basic membrane lipoprotein; COGs: COG1744 Uncharacterized ABC-type transport system periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: sta:STHERM_c17750 putative membrane lipopr [...]
AEC02334.1 protein networkhttps://string-db.org/network/760011.Spico_1113Fe(3+)-transporting ATPase; COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sfu:Sfum_1750 cobalt ABC transporter, ATPase subunit; PFAM: ABC tr [...]
AEC02335.1 protein networkhttps://string-db.org/network/760011.Spico_1114COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: dal:Dalk_0379 cobalt transport protein; PFAM: Cobalt transport protein; S [...]
AEC02336.1 protein networkhttps://string-db.org/network/760011.Spico_1115COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: bha:BH1417 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahy [...]
AEC02337.1 protein networkhttps://string-db.org/network/760011.Spico_1116Putative PTS IIA-like nitrogen-regulatory protein PtsN; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); KEGG: ssm:Spirs_1642 putative PTS IIA-like nitrog [...]
AEC02338.1 protein networkhttps://string-db.org/network/760011.Spico_1117Sulfide dehydrogenase (flavoprotein) subunit SudA; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR006004; KEGG: dap:Dacet_0223 gluta [...]
AEC02339.1 protein networkhttps://string-db.org/network/760011.Spico_1118Sulfide dehydrogenase (flavoprotein) subunit SudB; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433:IPR019480; KEGG: ssm:Spirs_1640 oxidoredu [...]
AEC02340.1 protein networkhttps://string-db.org/network/760011.Spico_1119Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: rfe:RF_1004 small heat shock protein; PFAM: Heat shock protein Hsp20; SPTR: Small [...]
AEC02341.1 protein networkhttps://string-db.org/network/760011.Spico_1120Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: csh:Closa_2870 transcriptional regulator, AraC family; P [...]
AEC02342.1 protein networkhttps://string-db.org/network/760011.Spico_1121COGs: COG4606 ABC-type enterochelin transport system permease component; InterPro IPR000522; KEGG: csh:Closa_2869 transport system permease protein; PFAM: ABC transporter permease protein; SPTR: [...]
AEC02343.1 protein networkhttps://string-db.org/network/760011.Spico_1122COGs: COG4605 ABC-type enterochelin transport system permease component; InterPro IPR000522; KEGG: csh:Closa_2868 transport system permease protein; PFAM: ABC transporter permease protein; SPTR: [...]
AEC02344.1 protein networkhttps://string-db.org/network/760011.Spico_1123COGs: COG4604 ABC-type enterochelin transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: bcy:Bcer98_0361 ABC transporter-related protein; PFAM: ABC transporter-like; PRIAM: Iron [...]
AEC02345.1 protein networkhttps://string-db.org/network/760011.Spico_1124Periplasmic binding protein; COGs: COG4607 ABC-type enterochelin transport system periplasmic component; InterPro IPR002491; KEGG: csh:Closa_2866 periplasmic binding protein; PFAM: Periplasmic bi [...]
AEC02346.1 protein networkhttps://string-db.org/network/760011.Spico_1125CRISPR-associated helicase Cas3; COGs: COG1203 helicase; InterPro IPR001650:IPR006483:IPR006474:IPR014001; KEGG: paa:Paes_1419 CRISPR-associated helicase Cas3; PFAM: Helicase, C-terminal; SMART: [...]
AEC02347.1 protein networkhttps://string-db.org/network/760011.Spico_1126InterPro IPR013381; KEGG: paa:Paes_1418 CRISPR-associated protein, CSE1 family; PFAM: CRISPR-associated protein Cse1; SPTR: CRISPR-associated protein, Cse1 family; TIGRFAM: CRISPR-associated prot [...]
AEC02348.1 protein networkhttps://string-db.org/network/760011.Spico_1127InterPro IPR013382; KEGG: dze:Dd1591_0910 CRISPR-associated protein, CSE2 family; PFAM: CRISPR-associated protein Cse2; SPTR: CRISPR-associated protein, Cse2 family; TIGRFAM: CRISPR-associated pr [...]
AEC02349.1 protein networkhttps://string-db.org/network/760011.Spico_1128InterPro IPR010179; KEGG: dal:Dalk_4936 CRISPR-associated protein, CSE3 family; PFAM: CRISPR-associated protein, CT1974; SPTR: CRISPR-associated protein, Cse3 family; TIGRFAM: CRISPR-associated p [...]
AEC02350.1 protein networkhttps://string-db.org/network/760011.Spico_1129InterPro IPR010148; KEGG: dze:Dd1591_0908 CRISPR-associated protein, CSE4 family; PFAM: CRISPR-associated protein, CT1975; SPTR: CRISPR-associated protein, Cse4 family; TIGRFAM: CRISPR-associated [...]
AEC02351.1 protein networkhttps://string-db.org/network/760011.Spico_1130CRISPR-associated protein Cas5 family; InterPro IPR010147:IPR013422; KEGG: cpb:Cphamn1_2163 CRISPR-associated protein Cas5 family; SPTR: CRISPR-associated protein Cas5 family; TIGRFAM: CRISPR-ass [...]
cas1 protein networkhttps://string-db.org/network/760011.Spico_1131CRISPR-associated protein, Cas1 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (v [...]
AEC02353.1 protein networkhttps://string-db.org/network/760011.Spico_1132InterPro IPR010152; KEGG: dal:Dalk_4940 CRISPR-associated protein Cas2; PFAM: CRISPR-associated protein Cas2 subtype; SPTR: CRISPR-associated protein, Cas2; TIGRFAM: CRISPR-associated protein Cas [...]
AEC02357.1 protein networkhttps://string-db.org/network/760011.Spico_1139KEGG: brm:Bmur_2766 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957447.
AEC02358.1 protein networkhttps://string-db.org/network/760011.Spico_1140KEGG: aau:AAur_3200 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957448; PFAM: Host cell surface-exposed lipoprotein.
AEC02359.1 protein networkhttps://string-db.org/network/760011.Spico_1142COGs: COG2865 transcriptional regulator protein; InterPro IPR007421; KEGG: gka:GK0575 hypothetical protein; PFAM: ATPase, AAA-4; SPTR: Putative uncharacterized protein; IMG reference gene:2503957 [...]
AEC02360.1 protein networkhttps://string-db.org/network/760011.Spico_1143SPTR: Putative uncharacterized protein; IMG reference gene:2503957451.
AEC02361.1 protein networkhttps://string-db.org/network/760011.Spico_1144KEGG: pru:PRU_1109 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957452.
AEC02362.1 protein networkhttps://string-db.org/network/760011.Spico_1145KEGG: vex:VEA_002903 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957453.
AEC02363.1 protein networkhttps://string-db.org/network/760011.Spico_1147Hypothetical protein; KEGG: hwa:HQ2045A phosphoesterase; SPTR: Putative uncharacterized protein; IMG reference gene:2503957455.
AEC02364.1 protein networkhttps://string-db.org/network/760011.Spico_1148KEGG: cce:Ccel_2675 transposase mutator type; SPTR: Transposase; IMG reference gene:2503957456.
AEC02365.1 protein networkhttps://string-db.org/network/760011.Spico_1149Hypothetical protein; KEGG: csa:Csal_0698 cell division protein ZipA; SPTR: Cell division protein zipA; IMG reference gene:2503957457.
AEC02366.1 protein networkhttps://string-db.org/network/760011.Spico_1150InterPro IPR013396; KEGG: mct:MCR_0030 CRISPR-associated Csy4 family protein; PFAM: CRISPR-associated protein Csy4; SPTR: Putative uncharacterized protein; TIGRFAM: CRISPR-associated protein Csy4 [...]
AEC02367.1 protein networkhttps://string-db.org/network/760011.Spico_1151CRISPR-associated protein, Csy3 family; InterPro IPR013399; KEGG: abb:ABBFA_000985 CRISPR-associated protein (Cas_Csy3) family protein; PFAM: CRISPR-associated protein Csy3; SPTR: CRISPR-associat [...]
AEC02368.1 protein networkhttps://string-db.org/network/760011.Spico_1152CRISPR-associated protein, Csy2 family; InterPro IPR013398; KEGG: abb:ABBFA_000984 CRISPR-associated protein (Cas_Csy2) family protein; PFAM: CRISPR-associated protein Csy2; SPTR: Putative unchar [...]
AEC02369.1 protein networkhttps://string-db.org/network/760011.Spico_1153CRISPR-associated protein, Csy1 family; InterPro IPR013397; KEGG: abb:ABBFA_000983 hypothetical protein; PFAM: CRISPR-associated protein Csy1; SPTR: Crispr-associated protein, Csy1 family; TIGRFA [...]
AEC02370.1 protein networkhttps://string-db.org/network/760011.Spico_1154CRISPR-associated helicase Cas3 family; COGs: COG1203 helicase; InterPro IPR013395; KEGG: shw:Sputw3181_2190 CRISPR-associated helicase Cas3 family protein; SPTR: Putative uncharacterized protein [...]
cas1-2 protein networkhttps://string-db.org/network/760011.Spico_1155CRISPR-associated protein, Cas1 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (v [...]
AEC02372.1 protein networkhttps://string-db.org/network/760011.Spico_1156Hypothetical protein; KEGG: fjo:Fjoh_2814 proline dehydrogenase; SPTR: Putative uncharacterized protein; IMG reference gene:2503957464.
AEC02373.1 protein networkhttps://string-db.org/network/760011.Spico_1157KEGG: cce:Ccel_2675 transposase mutator type; SPTR: Transposase; IMG reference gene:2503957465.
AEC02374.1 protein networkhttps://string-db.org/network/760011.Spico_1158Major facilitator superfamily MFS_1; InterPro IPR011701; KEGG: cbt:CLH_1564 transport protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Transport protein; IMG reference gene:2503957466; P [...]
AEC02375.1 protein networkhttps://string-db.org/network/760011.Spico_1159Radical SAM domain protein; COGs: COG1533 DNA repair photolyase; InterPro IPR007197; KEGG: scb:SCAB_43781 hypothetical protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein; IMG reference [...]
AEC02376.1 protein networkhttps://string-db.org/network/760011.Spico_1160Hypothetical protein; KEGG: clj:CLJU_c32650 putative prevent-host-death protein; SPTR: Putative prevent-host-death protein; IMG reference gene:2503957468.
AEC02377.1 protein networkhttps://string-db.org/network/760011.Spico_1161COGs: COG2865 transcriptional regulator protein; InterPro IPR007421; KEGG: pgi:PG1526 hypothetical protein; PFAM: ATPase, AAA-4; SPTR: Predicted transcriptional regulator containing an HTH domain [...]
AEC02379.1 protein networkhttps://string-db.org/network/760011.Spico_1165KEGG: cac:CA_C0063 hypothetical protein; SPTR: Putative tail fiber; IMG reference gene:2503957473.
AEC02380.1 protein networkhttps://string-db.org/network/760011.Spico_1166KEGG: ssm:Spirs_2813 hypothetical protein; SPTR: Phage minor structural protein, putative; IMG reference gene:2503957474.
AEC02381.1 protein networkhttps://string-db.org/network/760011.Spico_1167KEGG: ppg:PputGB1_1758 hypothetical protein; SPTR: Putative LigA; IMG reference gene:2503957475.
AEC02382.1 protein networkhttps://string-db.org/network/760011.Spico_1168Hypothetical protein; KEGG: dre:497403 im:7140452; SPTR: Tail tape meausure protein; IMG reference gene:2503957476.
AEC02383.1 protein networkhttps://string-db.org/network/760011.Spico_1169KEGG: ssm:Spirs_2813 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957477.
AEC02384.1 protein networkhttps://string-db.org/network/760011.Spico_1170KEGG: sha:SH1165 hypothetical protein; SPTR: Similar to FmtB/extracellular matrix binding protein; IMG reference gene:2503957478.
AEC02385.1 protein networkhttps://string-db.org/network/760011.Spico_1172Hypothetical protein; IMG reference gene:2503957480; PFAM: Oxaloacetate decarboxylase, gamma chain.
AEC02386.1 protein networkhttps://string-db.org/network/760011.Spico_1173COGs: COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; InterPro IPR005661; KEGG: csc:Csac_2482 sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+-t [...]
AEC02387.1 protein networkhttps://string-db.org/network/760011.Spico_1174TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148:IPR006037; KEGG: cpy:Cphy_1928 TrkA domain-containing protein; PFAM: Regulator of K+ conductanc [...]
AEC02388.1 protein networkhttps://string-db.org/network/760011.Spico_1175H(+)-transporting two-sector ATPase; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: cpy:Cphy_1927 H(+)-transporting two-sector ATPase; PFAM: Cation tra [...]
AEC02389.1 protein networkhttps://string-db.org/network/760011.Spico_1176TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148:IPR006037; KEGG: dap:Dacet_2986 TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-ter [...]
AEC02390.1 protein networkhttps://string-db.org/network/760011.Spico_1177Cation transporter; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: ddf:DEFDS_1538 K+ transport (Trk) system membrane component; PFAM: Cation transporte [...]
AEC02391.1 protein networkhttps://string-db.org/network/760011.Spico_1178KEGG: clj:CLJU_c17880 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957487; PFAM: DNA alkylation repair enzyme.
AEC02392.1 protein networkhttps://string-db.org/network/760011.Spico_1179COGs: COG2355 Zn-dependent dipeptidase microsomal dipeptidase homolog; InterPro IPR008257; KEGG: ctc:CTC00571 membrane dipeptidase; PFAM: Peptidase M19, renal dipeptidase; SPTR: Membrane dipeptid [...]
AEC02393.1 protein networkhttps://string-db.org/network/760011.Spico_1180Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766:IPR005746; KEGG: ddf:DEFDS_1167 thioredoxin; PFAM: Thioredoxin domain; SPTR: Thioredoxin; TIGRFAM: Thioredoxin [...]
AEC02394.1 protein networkhttps://string-db.org/network/760011.Spico_1181COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: har:HEAR2542 putative oxidoreductase; PFAM: Nitroreductase-like; SPTR: Nitroreductase; IMG reference gene:2503957490; PFAM: Nitroreductase [...]
AEC02395.1 protein networkhttps://string-db.org/network/760011.Spico_1182Protein of unknown function DUF161; COGs: COG1284 conserved hypothetical protein; InterPro IPR003740:IPR019264; KEGG: mta:Moth_0235 hypothetical protein; PFAM: Protein of unknown function DUF161; [...]
AEC02396.1 protein networkhttps://string-db.org/network/760011.Spico_1183COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR013131:IPR013118; KEGG: cpy:Cphy_1062 mannitol dehydrogenase domain-containing protein; PFAM: Mannitol dehydrogenase, C-ter [...]
AEC02397.1 protein networkhttps://string-db.org/network/760011.Spico_1184Transcriptional regulator, GntR family; COGs: COG1802 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: amt:Amet_3789 GntR family transcriptional regulator; PFAM: HTH transcriptiona [...]
uxuA protein networkhttps://string-db.org/network/760011.Spico_1185D-mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
AEC02399.1 protein networkhttps://string-db.org/network/760011.Spico_1186InterPro IPR000182; KEGG: ssm:Spirs_3745 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative uncharacterized protein; IMG reference gene:2503957 [...]
eno protein networkhttps://string-db.org/network/760011.Spico_1187Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
AEC02401.1 protein networkhttps://string-db.org/network/760011.Spico_1188Glycoside hydrolase family 2 sugar binding protein; COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104; KEGG: sro:Sros_3323 beta-galactosidase; PFAM: Glycoside hydrolase, fam [...]
AEC02402.1 protein networkhttps://string-db.org/network/760011.Spico_1189Major facilitator superfamily MFS_1; InterPro IPR011701; KEGG: sro:Sros_3322 hypothetical protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Putative uncharacterized protein; IMG reference [...]
recX protein networkhttps://string-db.org/network/760011.Spico_1190Regulatory protein recX; Modulates RecA activity; Belongs to the RecX family.
rpsI protein networkhttps://string-db.org/network/760011.Spico_1191COGs: COG0103 Ribosomal protein S9; InterPro IPR000754; KEGG: ssm:Spirs_3752 ribosomal protein S9; PFAM: Ribosomal protein S9; SPTR: 30S ribosomal protein S9; IMG reference gene:2503957500; PFAM: [...]
rplM protein networkhttps://string-db.org/network/760011.Spico_1192LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stage [...]
AEC02406.1 protein networkhttps://string-db.org/network/760011.Spico_1193KEGG: sta:STHERM_c21200 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957502; PFAM: Aminotransferase class-III.
AEC02407.1 protein networkhttps://string-db.org/network/760011.Spico_1194UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: ssm:Spirs_3757 UvrD/REP helicase; PFAM: DNA helicase, UvrD/REP type; SPTR: DNA helicase; IMG referen [...]
rimO protein networkhttps://string-db.org/network/760011.Spico_1195Ribosomal protein S12 methylthiotransferase rimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
AEC02409.1 protein networkhttps://string-db.org/network/760011.Spico_1196COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: sta:STHERM_c02770 oligopeptide ABC transporter permease; PFAM: Binding-protei [...]
AEC02410.1 protein networkhttps://string-db.org/network/760011.Spico_1197COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: sta:STHERM_c02780 oligopeptide ABC transporter permease, inner membrane compo [...]
AEC02411.1 protein networkhttps://string-db.org/network/760011.Spico_1198Oligopeptide/dipeptide ABC transporter, ATPase subunit; COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR003439:IPR013563:IPR010066:IPR003593; K [...]
AEC02412.1 protein networkhttps://string-db.org/network/760011.Spico_1199Oligopeptide/dipeptide ABC transporter, ATPase subunit; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003439:IPR013563:IPR010066:IPR [...]
AEC02413.1 protein networkhttps://string-db.org/network/760011.Spico_1200Hypothetical protein; KEGG: pst:PSPTO_3747 drug resistance transporter, EmrB/QacA family; SPTR: Cytochrome b; IMG reference gene:2503957509.
AEC02414.1 protein networkhttps://string-db.org/network/760011.Spico_1201Extracellular solute-binding protein family 5; COGs: COG4166 ABC-type oligopeptide transport system periplasmic component; InterPro IPR000914; KEGG: sta:STHERM_c02760 oligopeptide ABC transporter [...]
AEC02415.1 protein networkhttps://string-db.org/network/760011.Spico_1203COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: bha:BH0818 bacitracin ABC transporter ATP-binding protein; PFAM: ABC transporter-like; PRIA [...]
AEC02416.1 protein networkhttps://string-db.org/network/760011.Spico_1204KEGG: ere:EUBREC_3043 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957513.
AEC02417.1 protein networkhttps://string-db.org/network/760011.Spico_1205COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR001088; KEGG: csc:Csac_2748 glycoside hydrolase family protein; PFAM: Glycoside hydrolase, [...]
AEC02418.1 protein networkhttps://string-db.org/network/760011.Spico_1206Two component transcriptional regulator, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR000005:IPR01806 [...]
AEC02419.1 protein networkhttps://string-db.org/network/760011.Spico_1208Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: ate:Athe_2374 binding-protein-dependent t [...]
AEC02420.1 protein networkhttps://string-db.org/network/760011.Spico_1209COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ate:Athe_2375 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-pro [...]
AEC02421.1 protein networkhttps://string-db.org/network/760011.Spico_1210Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: ate:Athe_2376 extracellular solute-binding protein fa [...]
AEC02422.1 protein networkhttps://string-db.org/network/760011.Spico_1211NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: tit:Thit_2120 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimera [...]
AEC02423.1 protein networkhttps://string-db.org/network/760011.Spico_1212KEGG: cbe:Cbei_3173 TetR family transcriptional regulator; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2503957521.
AEC02424.1 protein networkhttps://string-db.org/network/760011.Spico_1213COGs: COG0095 Lipoate-protein ligase A; InterPro IPR004143:IPR019491:IPR004562; KEGG: cby:CLM_1876 putative lipoate-protein ligase A; PFAM: Biotin/lipoate A/B protein ligase; Lipoate protein liga [...]
AEC02425.1 protein networkhttps://string-db.org/network/760011.Spico_1214Glycine dehydrogenase (decarboxylating) beta subunit; COGs: COG1003 Glycine cleavage system protein P (pyridoxal-binding) C-terminal domain; InterPro IPR005814; KEGG: csh:Closa_1529 glycine dehyd [...]
gcvPA protein networkhttps://string-db.org/network/760011.Spico_1215Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal [...]
gcvH protein networkhttps://string-db.org/network/760011.Spico_1216Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
gcvT protein networkhttps://string-db.org/network/760011.Spico_1217Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
AEC02430.1 protein networkhttps://string-db.org/network/760011.Spico_1219Auxin Efflux Carrier; COGs: COG0679 permease; InterPro IPR004776; KEGG: ckr:CKR_1800 hypothetical protein; PFAM: Auxin efflux carrier; SPTR: Putative uncharacterized protein; IMG reference gene:2 [...]
AEC02431.1 protein networkhttps://string-db.org/network/760011.Spico_1220NADPH dehydrogenase; COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155; KEGG: cbe:Cbei_0562 NADH:flavin oxidoreductase/NADH oxidase; PFAM: NADH:flavin oxidored [...]
msrA protein networkhttps://string-db.org/network/760011.Spico_1221Peptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of met [...]
AEC02433.1 protein networkhttps://string-db.org/network/760011.Spico_1222Zinc/iron permease; COGs: COG0428 divalent heavy-metal cations transporter; InterPro IPR003689; KEGG: cce:Ccel_1427 zinc/iron permease; PFAM: Zinc/iron permease; SPTR: Zinc/iron permease; IMG ref [...]
AEC02434.1 protein networkhttps://string-db.org/network/760011.Spico_1223Ribonuclease BN; COGs: COG1295 membrane protein; InterPro IPR004664:IPR017039; KEGG: acd:AOLE_02310 tRNA-processing ribonuclease BN(RNase BN); PFAM: Ribonuclease BN-related; SPTR: Ribonuclease; T [...]
AEC02435.1 protein networkhttps://string-db.org/network/760011.Spico_1224Alpha/beta hydrolase fold protein; COGs: COG2267 Lysophospholipase; InterPro IPR000073; KEGG: amt:Amet_0462 alpha/beta hydrolase fold; PFAM: Alpha/beta hydrolase fold-1; SPTR: PLA depolymerase; I [...]
AEC02436.1 protein networkhttps://string-db.org/network/760011.Spico_1225Metallophosphoesterase; COGs: COG0622 phosphoesterase; InterPro IPR004843; KEGG: mta:Moth_0919 phosphodiesterase; PFAM: Metallo-dependent phosphatase; SPTR: Putative uncharacterized protein; IMG [...]
AEC02437.1 protein networkhttps://string-db.org/network/760011.Spico_1226Listeria/Bacterioides repeat-containing protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378:IPR011110:IPR000408; KEGG: mxa:MXAN_0889 RCC [...]
AEC02438.1 protein networkhttps://string-db.org/network/760011.Spico_1227COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983:IPR001203; KEGG: dol:Dole_1771 aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal; Aldeh [...]
AEC02439.1 protein networkhttps://string-db.org/network/760011.Spico_1228AAA ATPase; COGs: COG0572 Uridine kinase; InterPro IPR003593; KEGG: ssm:Spirs_3160 AAA ATPase; SMART: ATPase, AAA+ type, core; SPTR: Uridine kinase; IMG reference gene:2503957537; PFAM: Phosphori [...]
AEC02440.1 protein networkhttps://string-db.org/network/760011.Spico_1229Filamentation induced by cAMP protein Fic; COGs: COG3177 conserved hypothetical protein; InterPro IPR003812; KEGG: gox:GOX2572 hypothetical protein; PFAM: Filamentation induced by cAMP/death on c [...]
AEC02441.1 protein networkhttps://string-db.org/network/760011.Spico_1230COGs: COG2983 conserved hypothetical protein; KEGG: ssm:Spirs_3171 protein of unknown function UPF0153; SPTR: Putative cytoplasmic protein; manually curated; IMG reference gene:2503957539.
surE protein networkhttps://string-db.org/network/760011.Spico_1231Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
AEC02443.1 protein networkhttps://string-db.org/network/760011.Spico_1232Galactokinase; COGs: COG0153 Galactokinase; KEGG: ssm:Spirs_3175 galactokinase; PRIAM: Galactokinase; SPTR: Putative uncharacterized protein; IMG reference gene:2503957541; PFAM: Galactokinase ga [...]
rpmE protein networkhttps://string-db.org/network/760011.Spico_1233LSU ribosomal protein L31P; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
rho protein networkhttps://string-db.org/network/760011.Spico_1234Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
AEC02446.1 protein networkhttps://string-db.org/network/760011.Spico_1235CinA domain protein; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR001453:IPR008136; KEGG: ssm:Spirs_3180 competence/damage-inducible protein CinA; PFAM: [...]
lnt protein networkhttps://string-db.org/network/760011.Spico_1236Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrol [...]
AEC02448.1 protein networkhttps://string-db.org/network/760011.Spico_1237Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental con [...]
rpsT protein networkhttps://string-db.org/network/760011.Spico_123830S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
AEC02450.1 protein networkhttps://string-db.org/network/760011.Spico_1239PSP1 domain protein; COGs: COG1774 Uncharacterized homolog of PSP1; InterPro IPR007557; KEGG: sta:STHERM_c18600 hypothetical protein; PFAM: PSP1, C-terminal; SPTR: Putative uncharacterized protei [...]
AEC02451.1 protein networkhttps://string-db.org/network/760011.Spico_1240Major facilitator superfamily MFS_1; COGs: COG0738 Fucose permease; InterPro IPR011701; KEGG: csh:Closa_1055 major facilitator superfamily MFS_1; PFAM: Major facilitator superfamily MFS-1; SPTR: [...]
AEC02452.1 protein networkhttps://string-db.org/network/760011.Spico_1242Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130; KEGG: ssm:Spirs_3191 hydrolase, TatD family; PFAM: Deoxyribonuclease, TatD-related; SPTR: Putative uncharac [...]
AEC02453.1 protein networkhttps://string-db.org/network/760011.Spico_1243TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridin [...]
AEC02454.1 protein networkhttps://string-db.org/network/760011.Spico_1244Hypothetical protein; KEGG: pmy:Pmen_3843 alpha/beta hydrolase fold; SPTR: Alpha/beta hydrolase fold; IMG reference gene:2503957553.
AEC02455.1 protein networkhttps://string-db.org/network/760011.Spico_1245COGs: COG0151 Phosphoribosylamine-glycine ligase; InterPro IPR000115:IPR020562:IPR020561:IPR020560; KEGG: ssm:Spirs_3193 phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthe [...]
AEC02456.1 protein networkhttps://string-db.org/network/760011.Spico_1246Listeria/Bacterioides repeat-containing protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378:IPR011110:IPR000408; KEGG: aeh:Mlg_2687 regu [...]
AEC02457.1 protein networkhttps://string-db.org/network/760011.Spico_1247NADP-dependent oxidoreductase domain protein; COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR023210; KEGG: gym:GYMC10_1614 aldo/keto reductase; PFAM: NADP-depen [...]
AEC02458.1 protein networkhttps://string-db.org/network/760011.Spico_1248KEGG: ssm:Spirs_4225 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957557.
AEC02459.1 protein networkhttps://string-db.org/network/760011.Spico_1249Undecaprenyl-phosphate galactose phosphotransferase; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: ccb:Clocel_3670 undecaprenyl-phosphate glu [...]
AEC02460.1 protein networkhttps://string-db.org/network/760011.Spico_1250KEGG: xca:xccb100_1061 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957559.
AEC02461.1 protein networkhttps://string-db.org/network/760011.Spico_1251Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR011110:IPR000408; KEGG: aeh:Mlg_2687 regulator of chromos [...]
AEC02462.1 protein networkhttps://string-db.org/network/760011.Spico_1252InterPro IPR011435; KEGG: csh:Closa_3302 protein of unknown function DUF1538; PFAM: Protein of unknown function DUF1538; SPTR: Putative uncharacterized protein; IMG reference gene:2503957561; PFA [...]
AEC02463.1 protein networkhttps://string-db.org/network/760011.Spico_1254dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR005888:IPR001509; KEGG: cbe:Cbei_4754 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydrata [...]
rbsK-2 protein networkhttps://string-db.org/network/760011.Spico_1255Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histi [...]
AEC02465.1 protein networkhttps://string-db.org/network/760011.Spico_1256Inner-membrane translocator; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: dsh:Dshi_0528 ribose/xylose/arabinose/gala [...]
AEC02466.1 protein networkhttps://string-db.org/network/760011.Spico_1257Monosaccharide ABC transporter membrane protein, CUT2 family; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: dsh:Dshi_ [...]
AEC02467.1 protein networkhttps://string-db.org/network/760011.Spico_1258Monosaccharide ABC transporter ATP-binding protein, CUT2 family; COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: azl:AZL_b05830 simple sugar tr [...]
AEC02468.1 protein networkhttps://string-db.org/network/760011.Spico_1259Monosaccharide ABC transporter substrate-binding protein, CUT2 family; COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: dsh:Dshi_0531 ribose/xylose/arabinose/galactoside [...]
AEC02469.1 protein networkhttps://string-db.org/network/760011.Spico_1260Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: dap:Dacet_0215 transcriptional regulator, LacI family; PFAM: HTH transcriptio [...]
AEC02470.1 protein networkhttps://string-db.org/network/760011.Spico_1261Xylose isomerase domain-containing protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: pwa:Pecwa_2644 xylose isomerase domain protein TIM barrel; PFAM [...]
AEC02471.1 protein networkhttps://string-db.org/network/760011.Spico_1262Hypothetical protein; InterPro IPR011493; KEGG: swo:Swol_1078 Ig-like domain-containing protein; SPTR: Surface proteins containing Ig-like domains-like; IMG reference gene:2503957571; PFAM: The G [...]
AEC02472.1 protein networkhttps://string-db.org/network/760011.Spico_1263KEGG: bfr:BF3846 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957572.
AEC02473.1 protein networkhttps://string-db.org/network/760011.Spico_1264KEGG: bfs:BF1484 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957573.
AEC02474.1 protein networkhttps://string-db.org/network/760011.Spico_1265Hypothetical protein; KEGG: mpi:Mpet_0889 extracellular solute-binding protein family 5; SPTR: Putative uncharacterized protein; IMG reference gene:2503957574.
AEC02475.1 protein networkhttps://string-db.org/network/760011.Spico_1266Hypothetical protein; COGs: COG4571 Outer membrane protease; KEGG: tde:TDE2032 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957575; PFAM: Omptin family.
AEC02476.1 protein networkhttps://string-db.org/network/760011.Spico_1267KEGG: spw:SPCG_1762 subtilisin-like serine protease; SPTR: Putative uncharacterized protein; IMG reference gene:2503957576; PFAM: Subtilase family.
AEC02477.1 protein networkhttps://string-db.org/network/760011.Spico_1268AAA ATPase central domain protein; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593:IPR003959; KEGG: mmy:MSC_1062 AAA ATPase family protein; PFAM: ATPase, AAA-type, core; SMART: ATPase, [...]
AEC02478.1 protein networkhttps://string-db.org/network/760011.Spico_1269Conserved hypothetical protein CHP00730; COGs: COG1611 Rossmann fold nucleotide-binding protein; InterPro IPR005269; KEGG: gsu:GSU2766 decarboxylase family protein; PFAM: Cytokinin riboside 5'-mo [...]
AEC02479.1 protein networkhttps://string-db.org/network/760011.Spico_1270KEGG: tde:TDE0603 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957579.
AEC02480.1 protein networkhttps://string-db.org/network/760011.Spico_1272COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR003439; KEGG: cpy:Cphy_3379 ABC transporter transmembrane region; PFAM: ABC trans [...]
AEC02481.1 protein networkhttps://string-db.org/network/760011.Spico_1273COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR003439; KEGG: cpy:Cphy_3380 ABC transporter transmembrane region; PFAM: ABC trans [...]
AEC02482.1 protein networkhttps://string-db.org/network/760011.Spico_1274Transcriptional regulator, MarR family; COGs: COG1846 Transcriptional regulators; InterPro IPR000835; KEGG: cdl:CDR20291_3067 MarR-family transcriptional regulator; PFAM: HTH transcriptional regu [...]
AEC02483.1 protein networkhttps://string-db.org/network/760011.Spico_1275COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500; KEGG: cpy:Cphy_0491 hypothetical protein; PFAM: Ribose/galactose isomerase; SPTR: Putative uncharacterized protein; IMG refere [...]
AEC02484.1 protein networkhttps://string-db.org/network/760011.Spico_1276KEGG: tde:TDE1234 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957586.
AEC02485.1 protein networkhttps://string-db.org/network/760011.Spico_1277Transcriptional regulator, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR018060:IPR000005; KEGG: bpb:bpr_III019 [...]
AEC02486.1 protein networkhttps://string-db.org/network/760011.Spico_1278KEGG: str:Sterm_4037 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957588.
AEC02487.1 protein networkhttps://string-db.org/network/760011.Spico_1279Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: str:Sterm_4038 extracellular solute-binding protein f [...]
AEC02488.1 protein networkhttps://string-db.org/network/760011.Spico_1280COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: scb:SCAB_8181 putative integral membrane binding-protein-dependent transport protein; PFAM: Binding-p [...]
AEC02489.1 protein networkhttps://string-db.org/network/760011.Spico_1281COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: str:Sterm_4035 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-prot [...]
AEC02490.1 protein networkhttps://string-db.org/network/760011.Spico_1282COGs: COG0383 Alpha-mannosidase; InterPro IPR015341:IPR000602:IPR011682; KEGG: tit:Thit_1713 glycosyl hydrolase 38 domain protein; PFAM: Glycoside hydrolase, family 38, core; Glycoside hydrolase, [...]
AEC02491.1 protein networkhttps://string-db.org/network/760011.Spico_1283Glycosyl hydrolase family 88; COGs: COG4225 unsaturated glucuronyl hydrolase involved in regulation of surface properties and related protein; InterPro IPR010905; KEGG: bpb:bpr_III020 unsaturated [...]
AEC02492.1 protein networkhttps://string-db.org/network/760011.Spico_1284Listeria/Bacterioides repeat-containing protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378:IPR011110:IPR000408; KEGG: aeh:Mlg_2687 regu [...]
AEC02493.1 protein networkhttps://string-db.org/network/760011.Spico_1285Histidine triad (HIT) protein; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: ddf:DEFDS_1906 histidine triad family protein; P [...]
AEC02494.1 protein networkhttps://string-db.org/network/760011.Spico_1286Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COGs: COG1225 Peroxiredoxin; InterPro IPR000866; KEGG: hha:Hhal_0101 redoxin domain-containing protein; PFAM: Alkyl hydrop [...]
AEC02495.1 protein networkhttps://string-db.org/network/760011.Spico_1287Hypothetical protein; KEGG: sru:SRU_2861 endonuclease/exonuclease/phosphatase family protein; SPTR: Endonuclease/exonuclease/phosphatase family; IMG reference gene:2503957597.
AEC02496.1 protein networkhttps://string-db.org/network/760011.Spico_1288COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterPro IPR005146:IPR005147:IPR004531; KEGG: ssm:Spirs_4135 phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase, B5; PRIAM: [...]
pheS protein networkhttps://string-db.org/network/760011.Spico_1289COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; HAMAP: Phenylalanyl-tRNA synthetase alpha chain 2, bacterial/archaeal; InterPro IPR004529:IPR002319:IPR022917; KEGG: ssm:Spirs_4136 pheny [...]
AEC02498.1 protein networkhttps://string-db.org/network/760011.Spico_1290KEGG: ckr:CKR_2225 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957600.
AEC02499.1 protein networkhttps://string-db.org/network/760011.Spico_1291COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: bhy:BHWA1_00926 oxidoreductase domain containing protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C- [...]
AEC02500.1 protein networkhttps://string-db.org/network/760011.Spico_1292COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475:IPR001017:IPR005476; KEGG: jan:Jann_3081 dehydrogenase, E [...]
AEC02501.1 protein networkhttps://string-db.org/network/760011.Spico_1293KEGG: sta:STHERM_c16640 putative flavoredoxin; SPTR: Putative uncharacterized protein; IMG reference gene:2503957603.
AEC02502.1 protein networkhttps://string-db.org/network/760011.Spico_1294COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904:IPR000836; KEGG: dae:Dtox_0723 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Hyp [...]
AEC02503.1 protein networkhttps://string-db.org/network/760011.Spico_1295COGs: COG2236 phosphoribosyltransferase; InterPro IPR000836; KEGG: sta:STHERM_c19080 hypothetical protein; PFAM: Phosphoribosyltransferase; SPTR: Putative uncharacterized protein; IMG reference g [...]
purA protein networkhttps://string-db.org/network/760011.Spico_1296Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to t [...]
AEC02505.1 protein networkhttps://string-db.org/network/760011.Spico_1297Extracellular solute-binding protein family 1; COGs: COG0687 Spermidine/putrescine-binding periplasmic protein; InterPro IPR006059; KEGG: tpp:TPASS_0655 spermidine/putrescine ABC transporter, per [...]
AEC02506.1 protein networkhttps://string-db.org/network/760011.Spico_1298Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378:IPR000408; KEGG: mxa:MXAN_0889 RCC1 repeat-contain [...]
AEC02507.1 protein networkhttps://string-db.org/network/760011.Spico_1299COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR022761:IPR019468; KEGG: cpy:Cphy_3043 adenylosuccinate lyase; PFAM: Lyase 1, N-terminal; Adenylosuccinate lyase C-terminal metazoa/fung [...]
AEC02508.1 protein networkhttps://string-db.org/network/760011.Spico_1300InterPro IPR015414; KEGG: neu:NE1198 hypothetical protein; PFAM: SNARE associated Golgi protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957610; PFAM: SNARE associated Golg [...]
AEC02509.1 protein networkhttps://string-db.org/network/760011.Spico_1301Alanyl-tRNA synthetase, class IIc; COGs: COG2872 metal-dependent hydrolase related to alanyl-tRNA synthetase HxxxH domain; InterPro IPR012947:IPR018164; KEGG: ssm:Spirs_0879 alanyl-tRNA synthetas [...]
AEC02510.1 protein networkhttps://string-db.org/network/760011.Spico_1302KEGG: ssm:Spirs_0875 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957612.
AEC02511.1 protein networkhttps://string-db.org/network/760011.Spico_1303Hypothetical protein; KEGG: dac:Daci_0587 cytochrome c biogenesis protein transmembrane region; SPTR: Cytochrome c biogenesis protein transmembrane region; IMG reference gene:2503957613.
AEC02512.1 protein networkhttps://string-db.org/network/760011.Spico_1304KEGG: gpb:HDN1F_10950 hypothetical protein; SPTR: Diheme Cytochrome c-type; IMG reference gene:2503957615.
AEC02513.1 protein networkhttps://string-db.org/network/760011.Spico_1305KEGG: osa:4345910 hypothetical protein; SPTR: Whole genome shotgun sequence assembly, scaffold_63; IMG reference gene:2503957616.
AEC02514.1 protein networkhttps://string-db.org/network/760011.Spico_1306Protein of unknown function DUF541; COGs: COG2968 conserved hypothetical protein; InterPro IPR007497; KEGG: nha:Nham_3577 hypothetical protein; PFAM: Protein of unknown function DUF541; SPTR: Put [...]
AEC02515.1 protein networkhttps://string-db.org/network/760011.Spico_1307NUDIX hydrolase; InterPro IPR000086; KEGG: ssm:Spirs_0637 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: MutT/nudix family protein; IMG reference gene:2503957618; PFAM: NUDIX domain; Belong [...]
AEC02516.1 protein networkhttps://string-db.org/network/760011.Spico_1308ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
AEC02517.1 protein networkhttps://string-db.org/network/760011.Spico_1309Hypothetical protein; KEGG: rop:ROP_14030 putative serine/threonine protein kinase; SPTR: Putative serine/threonine protein kinase; IMG reference gene:2503957620.
AEC02518.1 protein networkhttps://string-db.org/network/760011.Spico_1310COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891:IPR000089; KEGG: ssm:Spirs_4017 biotin/lipoyl attachment domain-containing protein; PFAM: Biotin/lipoyl attachment; Pyr [...]
AEC02519.1 protein networkhttps://string-db.org/network/760011.Spico_1311dCMP deaminase; COGs: COG2131 Deoxycytidylate deaminase; InterPro IPR002125; KEGG: clo:HMPREF0868_0032 cytidine and deoxycytidylate deaminase zinc-binding region; PFAM: CMP/dCMP deaminase, zinc-b [...]
AEC02520.1 protein networkhttps://string-db.org/network/760011.Spico_1312Hypothetical protein; KEGG: seu:SEQ_1013 signal peptidase I; SPTR: Putative signal peptidase I; IMG reference gene:2503957623.
AEC02521.1 protein networkhttps://string-db.org/network/760011.Spico_1313Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR022689:IPR022687:IPR001367; KEGG: dhd:Dhaf_1581 iron (metal) dependent rep [...]
AEC02522.1 protein networkhttps://string-db.org/network/760011.Spico_13142-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
AEC02523.1 protein networkhttps://string-db.org/network/760011.Spico_13153'-5' exonuclease; COGs: COG0349 Ribonuclease D; InterPro IPR002562; KEGG: ssm:Spirs_1372 3'-5' exonuclease; PFAM: 3'-5' exonuclease; SMART: 3'-5' exonuclease; SPTR: 3'-5' exonuclease; IMG refere [...]
pckG protein networkhttps://string-db.org/network/760011.Spico_1316Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from la [...]
AEC02525.1 protein networkhttps://string-db.org/network/760011.Spico_1317Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEG [...]
AEC02526.1 protein networkhttps://string-db.org/network/760011.Spico_1318Peptidase U32; COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: sta:STHERM_c21690 hypothetical protein; PFAM: Peptidase U32; SPTR: Putative uncharacterized protein; IMG r [...]
AEC02527.1 protein networkhttps://string-db.org/network/760011.Spico_1319COGs: COG0136 Aspartate-semialdehyde dehydrogenase; InterPro IPR000534:IPR005676:IPR012280; KEGG: ssm:Spirs_4027 aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD-bindin [...]
AEC02528.1 protein networkhttps://string-db.org/network/760011.Spico_1321KEGG: blo:BL0787 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957632; PFAM: Protein of unknown function (DUF2974).
AEC02529.1 protein networkhttps://string-db.org/network/760011.Spico_1322Transposase IS4 family protein; COGs: COG5421 Transposase; InterPro IPR002559; KEGG: cob:COB47_1677 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family prote [...]
guaA protein networkhttps://string-db.org/network/760011.Spico_1324GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
AEC02531.1 protein networkhttps://string-db.org/network/760011.Spico_1325Protein of unknown function DUF1393; COGs: COG4720 membrane protein; InterPro IPR009825; KEGG: tko:TK2102 hypothetical protein; PFAM: Protein of unknown function DUF1393; SPTR: Hypothetical membr [...]
AEC02532.1 protein networkhttps://string-db.org/network/760011.Spico_1326COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: sti:Sthe_3088 cobalt transport protein; PFAM: Cobalt transport protein; S [...]
AEC02533.1 protein networkhttps://string-db.org/network/760011.Spico_1327ABC transporter related protein; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003593:IPR003439; KEGG: bad:BAD_0600 ABC-type cobalt [...]
AEC02534.1 protein networkhttps://string-db.org/network/760011.Spico_1328COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: ssm:Spirs_3805 phospholipid/glycerol acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; SMART: P [...]
AEC02535.1 protein networkhttps://string-db.org/network/760011.Spico_1329COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR003439; KEGG: ssm:Spirs_4147 ABC transporter related protein; PFAM: ABC transport [...]
AEC02536.1 protein networkhttps://string-db.org/network/760011.Spico_1330DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR011545; KEGG: ssm:Spirs_3800 DEAD/DEAH box helicase domain protein; PFAM: [...]
AEC02537.1 protein networkhttps://string-db.org/network/760011.Spico_1331Aminotransferase class IV; COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544; KEGG: ssm:Spirs_0479 aminotransferase class IV; PFAM: Amin [...]
AEC02538.1 protein networkhttps://string-db.org/network/760011.Spico_1332Cell division protein FtsK/SpoIIIE; COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR003593:IPR018541:IPR002543; KEGG: ssm:Spirs_3823 cell division protein FtsK/ [...]
rsmG protein networkhttps://string-db.org/network/760011.Spico_1333Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
mnmG protein networkhttps://string-db.org/network/760011.Spico_1334tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
mnmE protein networkhttps://string-db.org/network/760011.Spico_1335tRNA modification GTPase mnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain t [...]
AEC02542.1 protein networkhttps://string-db.org/network/760011.Spico_1336Lysine--tRNA ligase; COGs: COG2269 Truncated possibly inactive lysyl-tRNA synthetase (class II); InterPro IPR004364; KEGG: ssm:Spirs_3665 tRNA synthetase class II (D K and N); PFAM: Aminoacyl-tRN [...]
efp protein networkhttps://string-db.org/network/760011.Spico_1337Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably [...]
AEC02544.1 protein networkhttps://string-db.org/network/760011.Spico_1338Lysine 2,3-aminomutase YodO family protein; COGs: COG1509 Lysine 2 3-aminomutase; InterPro IPR003739:IPR007197; KEGG: afw:Anae109_1316 lysine 2,3-aminomutase YodO family protein; PFAM: Radical SA [...]
AEC02545.1 protein networkhttps://string-db.org/network/760011.Spico_1339Major facilitator superfamily MFS_1; COGs: COG2211 Na+/melibiose symporter and related transporter; InterPro IPR011701; KEGG: ssm:Spirs_3673 major facilitator superfamily MFS_1; PFAM: Major facil [...]
AEC02546.1 protein networkhttps://string-db.org/network/760011.Spico_1340YhhN family protein; InterPro IPR012506; KEGG: sgr:SGR_5669 hypothetical protein; PFAM: YhhN-like; SPTR: YhhN family protein; IMG reference gene:2503957652; PFAM: YhhN-like protein.
AEC02547.1 protein networkhttps://string-db.org/network/760011.Spico_1341Hypothetical protein; InterPro IPR011493; KEGG: hwa:HQ1081A halomucin; SPTR: Halomucin; IMG reference gene:2503957653.
AEC02548.1 protein networkhttps://string-db.org/network/760011.Spico_1342KEGG: pfa:PF10_0351 probable protein; SPTR: Probable protein; IMG reference gene:2503957654.
coaE protein networkhttps://string-db.org/network/760011.Spico_1343Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
polA protein networkhttps://string-db.org/network/760011.Spico_1344DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
AEC02551.1 protein networkhttps://string-db.org/network/760011.Spico_1345Beta-lactamase domain protein; COGs: COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I; InterPro IPR001279; KEGG: ssm:Spirs_3682 beta-lactamase domain protein; PFAM: Beta-lact [...]
AEC02552.1 protein networkhttps://string-db.org/network/760011.Spico_1346KEGG: ani:AN1767.2 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957658.
AEC02553.1 protein networkhttps://string-db.org/network/760011.Spico_1347Hypothetical protein; KEGG: gem:GM21_0672 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:250395 [...]
AEC02554.1 protein networkhttps://string-db.org/network/760011.Spico_1348KEGG: pic:PICST_57741 hypothetical protein; SPTR: Probable outer membrane porin; IMG reference gene:2503957660.
nadE protein networkhttps://string-db.org/network/760011.Spico_1349NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
AEC02556.1 protein networkhttps://string-db.org/network/760011.Spico_1350(Uracil-5)-methyltransferase; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR010280; KEGG: aca:ACP_2578 23S rRNA (uracil-5-)-methyltransf [...]
AEC02557.1 protein networkhttps://string-db.org/network/760011.Spico_1351Peptidase M3A and M3B thimet/oligopeptidase F; COGs: COG1164 Oligoendopeptidase F; InterPro IPR013647:IPR001567; KEGG: tde:TDE2001 oligoendopeptidase F, putative; PFAM: Peptidase M3A/M3B, thimet/ [...]
AEC02558.1 protein networkhttps://string-db.org/network/760011.Spico_1352Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789: [...]
AEC02559.1 protein networkhttps://string-db.org/network/760011.Spico_1353COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: ssm:Spirs_0495 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-bindin [...]
AEC02560.1 protein networkhttps://string-db.org/network/760011.Spico_1354Protein of unknown function DUF214; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: sta:STHERM_c10100 hypothetical protein; PFAM: Domai [...]
AEC02561.1 protein networkhttps://string-db.org/network/760011.Spico_1355Phosphonate-transporting ATPase; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: cpc:Cpar_0807 ABC transporter related; PFAM: A [...]
AEC02562.1 protein networkhttps://string-db.org/network/760011.Spico_1356Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: tde:TDE2284 RND family efflux transporter MFP subunit; PFAM: Secretion protein HlyD; [...]
AEC02563.1 protein networkhttps://string-db.org/network/760011.Spico_1357Hypothetical protein; KEGG: tgu:100231991 dual specificity phosphatase 27 (putative); SPTR: Outer membrane efflux protein; IMG reference gene:2503957669.
AEC02564.1 protein networkhttps://string-db.org/network/760011.Spico_1358Hsp33 protein; COGs: COG1281 Disulfide bond chaperones of the HSP33 family; InterPro IPR000397; KEGG: ssm:Spirs_0341 HSP33 protein; PFAM: Heat shock protein Hsp33 protein; SPTR: Chaperonin HslO; [...]
rlmL protein networkhttps://string-db.org/network/760011.Spico_1359Ribosomal RNA large subunit methyltransferase L; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransf [...]
mscL protein networkhttps://string-db.org/network/760011.Spico_1360Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within th [...]
AEC02567.1 protein networkhttps://string-db.org/network/760011.Spico_1361Filamentation induced by cAMP protein Fic; COGs: COG2184 Protein involved in cell division; InterPro IPR003812; KEGG: hmo:HM1_0604 cell filamentation protein fic, putative; PFAM: Filamentation in [...]
AEC02568.1 protein networkhttps://string-db.org/network/760011.Spico_1362KEGG: alv:Alvin_0840 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957674.
AEC02569.1 protein networkhttps://string-db.org/network/760011.Spico_1363ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: ssm:Spirs_1400 ROK family protein; PFAM: ROK; SPTR: Putative transcriptional regulator; IMG ref [...]
AEC02570.1 protein networkhttps://string-db.org/network/760011.Spico_1365UPF0597 protein yhaM; COGs: COG3681 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0597; InterPro IPR021144; KEGG: bpo:BP951000_1867 hypothetical protein; SPTR: Putative [...]
AEC02571.1 protein networkhttps://string-db.org/network/760011.Spico_1366KEGG: osa:4351396 hypothetical protein; SPTR: M18 family aminopeptidase; IMG reference gene:2503957678.
AEC02572.1 protein networkhttps://string-db.org/network/760011.Spico_1367COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: csh:Closa_1292 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-prot [...]
AEC02573.1 protein networkhttps://string-db.org/network/760011.Spico_1368COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: csh:Closa_1291 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-pr [...]
AEC02574.1 protein networkhttps://string-db.org/network/760011.Spico_1369Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: csh:Closa_1290 extracellular solute-binding protein f [...]
AEC02575.1 protein networkhttps://string-db.org/network/760011.Spico_1370Hypothetical protein; KEGG: csh:Closa_1289 uroporphyrinogen-III decarboxylase-like protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957682; PFAM: Uroporphyrinogen decarboxy [...]
AEC02576.1 protein networkhttps://string-db.org/network/760011.Spico_1371YheO-like domain-containing protein; COGs: COG2964 conserved hypothetical protein; InterPro IPR013559; KEGG: hiq:CGSHiGG_06150 hypothetical protein; PFAM: YheO-like; SPTR: Putative uncharacterize [...]
AEC02577.1 protein networkhttps://string-db.org/network/760011.Spico_1372COGs: COG4821 Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain; KEGG: tpe:Tpen_1090 hypothetical protein; SPTR: Phosphoheptose isomerase, putative; IMG referen [...]
AEC02578.1 protein networkhttps://string-db.org/network/760011.Spico_1373Hypothetical protein; KEGG: hmg:100208216 similar to Collagen alpha-5(VI) chain; SPTR: Hemagglutinin-neuraminidase; IMG reference gene:2503957685.
AEC02579.1 protein networkhttps://string-db.org/network/760011.Spico_1374KEGG: aoe:Clos_2735 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957686.
AEC02580.1 protein networkhttps://string-db.org/network/760011.Spico_1375KEGG: cbe:Cbei_1260 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957687.
trpS protein networkhttps://string-db.org/network/760011.Spico_1376tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
AEC02582.1 protein networkhttps://string-db.org/network/760011.Spico_1377Magnesium-translocating P-type ATPase; COGs: COG0474 Cation transport ATPase; InterProIPR004014:IPR006415:IPR001757:IPR008250:IPR 005834:IPR006068; KEGG: acl:ACL_1281 magnesium transporting ATPas [...]
AEC02583.1 protein networkhttps://string-db.org/network/760011.Spico_1378Peptidoglycan-binding lysin domain protein; COGs: COG1912 conserved hypothetical protein; KEGG: ssm:Spirs_0807 peptidoglycan-binding lysin domain protein; SPTR: Putative uncharacterized protein; [...]
AEC02584.1 protein networkhttps://string-db.org/network/760011.Spico_1380COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: cth:Cthe_2799 cystathionine gamma-synthase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent [...]
AEC02585.1 protein networkhttps://string-db.org/network/760011.Spico_1381Two component transcriptional regulator, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR018060:IPR00000 [...]
AEC02586.1 protein networkhttps://string-db.org/network/760011.Spico_1382Integral membrane sensor signal transduction histidine kinase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR003594:IPR010559; KEGG: csh:Closa_1 [...]
AEC02587.1 protein networkhttps://string-db.org/network/760011.Spico_1383Carbohydrate ABC transporter substrate-binding protein, CUT1 family; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: cpy:Cphy_0291 extracellular sol [...]
AEC02588.1 protein networkhttps://string-db.org/network/760011.Spico_1384Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: cpy:Cphy_0290 binding-protein-dependent [...]
AEC02589.1 protein networkhttps://string-db.org/network/760011.Spico_1385Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: cpy:Cphy_0289 binding-protein-dependent t [...]
AEC02590.1 protein networkhttps://string-db.org/network/760011.Spico_1386InterPro IPR012480; KEGG: cpy:Cphy_3022 heparinase II/III family protein; PFAM: Heparinase II/III-like; SPTR: Heparinase II/III family protein; IMG reference gene:2503957698; PFAM: Heparinase II/ [...]
AEC02591.1 protein networkhttps://string-db.org/network/760011.Spico_13873-oxoacyl-(acyl-carrier-protein) reductase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: cce:Ccel_2618 short- [...]
AEC02592.1 protein networkhttps://string-db.org/network/760011.Spico_1388Hypothetical protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR011110; KEGG: aeh:Mlg_2687 regulator of chromosome condensation, RCC1; SPTR: P [...]
AEC02593.1 protein networkhttps://string-db.org/network/760011.Spico_1389Hypothetical protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR011110; KEGG: aeh:Mlg_2687 regulator of chromosome condensation, RCC1; SPTR: P [...]
AEC02594.1 protein networkhttps://string-db.org/network/760011.Spico_1390Protein of unknown function DUF1006; COGs: COG3214 conserved hypothetical protein; InterPro IPR009351; KEGG: bbe:BBR47_29660 hypothetical protein; PFAM: Protein of unknown function DUF1006; SPTR: [...]
AEC02595.1 protein networkhttps://string-db.org/network/760011.Spico_1391Protein of unknown function DUF62; COGs: COG1912 conserved hypothetical protein; InterPro IPR002747; KEGG: sga:GALLO_1836 hypothetical protein; PFAM: Protein of unknown function DUF62; SPTR: Puta [...]
AEC02596.1 protein networkhttps://string-db.org/network/760011.Spico_1392Protein of unknown function DUF62; COGs: COG1912 conserved hypothetical protein; InterPro IPR002747; KEGG: lbu:LBUL_1585 hypothetical protein; PFAM: Protein of unknown function DUF62; SPTR: Putat [...]
AEC02597.1 protein networkhttps://string-db.org/network/760011.Spico_1393Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933:IPR011650; KEGG: gtn:GTNG_2735 Xaa-His dipeptidas [...]
AEC02598.1 protein networkhttps://string-db.org/network/760011.Spico_1394COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: ssm:Spirs_3591 cobalt transport protein; PFAM: Cobalt transport protein; [...]
AEC02599.1 protein networkhttps://string-db.org/network/760011.Spico_1395COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003593:IPR003439; KEGG: ssm:Spirs_3590 ABC transporter related protein; PFAM: ABC tran [...]
AEC02600.1 protein networkhttps://string-db.org/network/760011.Spico_1396InterPro IPR009825; KEGG: ssm:Spirs_3589 protein of unknown function DUF1393; PFAM: Protein of unknown function DUF1393; SPTR: Substrate-specific component MtsA of methionine-regulated ECF transp [...]
AEC02601.1 protein networkhttps://string-db.org/network/760011.Spico_1397Hypothetical protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR011110; KEGG: aeh:Mlg_2687 regulator of chromosome condensation, RCC1; SPTR: P [...]
AEC02602.1 protein networkhttps://string-db.org/network/760011.Spico_1398Monosaccharide ABC transporter membrane protein, CUT2 family; COGs: COG4211 ABC-type glucose/galactose transport system permease component; InterPro IPR001851; KEGG: tde:TDE2215 galactoside ABC t [...]
AEC02603.1 protein networkhttps://string-db.org/network/760011.Spico_1399Monosaccharide ABC transporter ATP-binding protein, CUT2 family; COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: tde:TDE2216 galactoside ABC tr [...]
AEC02604.1 protein networkhttps://string-db.org/network/760011.Spico_1400Monosaccharide ABC transporter substrate-binding protein, CUT2 family; COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: tde:TDE2217 galactose/glucose-binding lipoprotein [...]
AEC02605.1 protein networkhttps://string-db.org/network/760011.Spico_1401Two component transcriptional regulator, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR018060:IPR00000 [...]
AEC02606.1 protein networkhttps://string-db.org/network/760011.Spico_1402Multi-sensor signal transduction histidine kinase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR003594:IPR004010:IPR010559; KEGG: ccb:Clocel_38 [...]
AEC02607.1 protein networkhttps://string-db.org/network/760011.Spico_1403Hypothetical protein; COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: cpy:Cphy_2251 periplasmic binding protein/LacI transcriptional regulator; SPTR: Putative uncharact [...]
AEC02608.1 protein networkhttps://string-db.org/network/760011.Spico_1404Monosaccharide ABC transporter substrate-binding protein, CUT2 family; COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: bbe:BBR47_06800 D-galactose ABC transporter subst [...]
AEC02609.1 protein networkhttps://string-db.org/network/760011.Spico_1405Listeria/Bacterioides repeat-containing protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378:IPR011110:IPR000408; KEGG: aeh:Mlg_2687 regu [...]
AEC02610.1 protein networkhttps://string-db.org/network/760011.Spico_1406Amino acid ABC transporter membrane protein 2, PAAT family; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR010065:IPR000515; KEGG: dhd:Dhaf_1045 polar amino ac [...]
AEC02611.1 protein networkhttps://string-db.org/network/760011.Spico_1407Amino acid ABC transporter membrane protein 1, PAAT family; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR010065:IPR000515; KEGG: dsy:DSY4276 hypothetical pro [...]
AEC02612.1 protein networkhttps://string-db.org/network/760011.Spico_1408Amino acid ABC transporter substrate-binding protein, PAAT family; COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638; KEGG: [...]
AEC02613.1 protein networkhttps://string-db.org/network/760011.Spico_1409Amino acid ABC transporter ATP-binding protein, PAAT family; COGs: COG1126 ABC-type polar amino acid transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: toc:Toce_1570 amino aci [...]
AEC02614.1 protein networkhttps://string-db.org/network/760011.Spico_1410Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic poten [...]
AEC02615.1 protein networkhttps://string-db.org/network/760011.Spico_1411MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thio [...]
AEC02616.1 protein networkhttps://string-db.org/network/760011.Spico_1412Hypothetical protein; KEGG: mxa:MXAN_2924 general secretion pathway protein E; IMG reference gene:2503957724.
AEC02617.1 protein networkhttps://string-db.org/network/760011.Spico_1413COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: cac:CA_C0427 glycerol-3-phosphate ABC-transporter, permease component; PFAM: Binding-protein-dependen [...]
AEC02618.1 protein networkhttps://string-db.org/network/760011.Spico_1414Binding-protein-dependent transport systems inner membrane component; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: cac:CA_C0428 sugar permease; PFAM [...]
AEC02619.1 protein networkhttps://string-db.org/network/760011.Spico_1415Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: apr:Apre_0061 extracellular solute-binding protein fa [...]
AEC02620.1 protein networkhttps://string-db.org/network/760011.Spico_1416Xylose isomerase domain-containing protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: toc:Toce_0893 xylose isomerase domain protein TIM barrel; PFAM: [...]
AEC02621.1 protein networkhttps://string-db.org/network/760011.Spico_1417Transcriptional regulator, MerR family; COGs: COG0789 transcriptional regulator protein; InterPro IPR000551; KEGG: seq:SZO_16670 MerR family regulatory protein; PFAM: HTH transcriptional regulato [...]
AEC02622.1 protein networkhttps://string-db.org/network/760011.Spico_1418COGs: COG2003 DNA repair protein; InterPro IPR001405; KEGG: ssm:Spirs_3489 DNA repair protein RadC; PFAM: Uncharacterised protein family UPF0758; SPTR: DNA repair protein; TIGRFAM: Uncharacterise [...]
AEC02623.1 protein networkhttps://string-db.org/network/760011.Spico_1419Cation diffusion facilitator family transporter; COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: cbf:CLI_1359 cation efflux family protein; PFAM: Cation efflux protein; SPTR: [...]
hisI protein networkhttps://string-db.org/network/760011.Spico_1420Phosphoribosyl-ATP pyrophosphatase; COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; HAMAP: Phosphoribosyl-ATP pyrophosphohydrolase; Histidine biosynthesis bifunctional protein HisIE; InterPro IP [...]
hisF protein networkhttps://string-db.org/network/760011.Spico_1421Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that prod [...]
hisA protein networkhttps://string-db.org/network/760011.Spico_14221-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) iso [...]
hisH protein networkhttps://string-db.org/network/760011.Spico_1423Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glu [...]
hisB protein networkhttps://string-db.org/network/760011.Spico_1424COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; HAMAP: Imidazoleglycerol-phosphate dehydratase; InterPro IPR006543:IPR006549:IPR000807; KEGG: chu:CHU_1270 imidazole glycerol-phosphate dehy [...]
hisC protein networkhttps://string-db.org/network/760011.Spico_1425COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; HAMAP: Histidinol-phosphate aminotransferase; InterPro IPR005861:IPR004839; KEGG: pdi:BDI_0968 histidi [...]
hisD protein networkhttps://string-db.org/network/760011.Spico_1426Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
hisG protein networkhttps://string-db.org/network/760011.Spico_1427ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate [...]
AEC02632.1 protein networkhttps://string-db.org/network/760011.Spico_1428KEGG: sti:Sthe_2657 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957740.
AEC02633.1 protein networkhttps://string-db.org/network/760011.Spico_1429HAD superfamily (subfamily IA) hydrolase, TIGR02254; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR011951:IPR006439:IPR005834; KEGG: rcu:RCOM_2074390 5'-nucleotidase yjjG, putative; PFAM [...]
AEC02634.1 protein networkhttps://string-db.org/network/760011.Spico_1430COGs: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerase 1; InterPro IPR000774:IPR001179; KEGG: dol:Dole_1577 peptidylprolyl isomerase FKBP-type; PFAM: Peptidyl-prolyl cis-trans isomerase, FKB [...]
aroA protein networkhttps://string-db.org/network/760011.Spico_14313-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl [...]
AEC02636.1 protein networkhttps://string-db.org/network/760011.Spico_1432COGs: COG2008 Threonine aldolase; InterPro IPR001597; KEGG: ssm:Spirs_3940 threonine aldolase; PFAM: Aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Threonine aldolase; SPTR [...]
AEC02637.1 protein networkhttps://string-db.org/network/760011.Spico_1433Cystathionine beta-lyase; COGs: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; InterPro IPR004839; KEGG: cbi:CLJ_B1515 aminotransferas [...]
AEC02638.1 protein networkhttps://string-db.org/network/760011.Spico_1434UvrD/REP helicase; COGs: COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); InterPro IPR000212; KEGG: ssm:Spirs_3944 UvrD/REP helicase; PFAM: [...]
AEC02639.1 protein networkhttps://string-db.org/network/760011.Spico_1435KEGG: ssm:Spirs_3945 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957747.
AEC02640.1 protein networkhttps://string-db.org/network/760011.Spico_1436Abortive infection protein; InterPro IPR003675; KEGG: rrs:RoseRS_4016 abortive infection protein; PFAM: Abortive infection protein; SPTR: Abortive infection protein; IMG reference gene:2503957748 [...]
AEC02641.1 protein networkhttps://string-db.org/network/760011.Spico_1437COGs: COG1864 DNA/RNA endonuclease G NUC1; InterPro IPR001604:IPR020821; KEGG: cts:Ctha_1807 DNA/RNA non-specific endonuclease; PFAM: DNA/RNA non-specific endonuclease; SMART: DNA/RNA non-specifi [...]
AEC02642.1 protein networkhttps://string-db.org/network/760011.Spico_1438Glycerol-1-phosphate dehydrogenase (NAD(P)(+)); COGs: COG0371 Glycerol dehydrogenase; InterPro IPR002658; KEGG: bcv:Bcav_1503 glycerol-1-phosphate dehydrogenase (NAD(P)(+)); PFAM: 3-dehydroquinat [...]
AEC02644.1 protein networkhttps://string-db.org/network/760011.Spico_1440KEGG: gdj:Gdia_2446 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957753.
AEC02645.1 protein networkhttps://string-db.org/network/760011.Spico_1441KEGG: osa:4332786 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957754.
AEC02646.1 protein networkhttps://string-db.org/network/760011.Spico_1442Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; COGs: COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I C-terminal domain; InterPro IPR004647; KEGG: dly:Dehl [...]
AEC02647.1 protein networkhttps://string-db.org/network/760011.Spico_1443Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; COGs: COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I N-terminal domain; InterPro IPR004646; KEGG: dds:Dd [...]
AEC02648.1 protein networkhttps://string-db.org/network/760011.Spico_1444VanZ family protein; InterPro IPR006976; KEGG: hne:HNE_2912 hypothetical protein; PFAM: VanZ-like; SPTR: Putative membrane protein; IMG reference gene:2503957757; PFAM: VanZ like family.
AEC02649.1 protein networkhttps://string-db.org/network/760011.Spico_1445Radical SAM domain protein; COGs: COG1242 Fe-S oxidoreductase; InterPro IPR006638:IPR007197; KEGG: sta:STHERM_c02000 radical SAM protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; [...]
AEC02650.1 protein networkhttps://string-db.org/network/760011.Spico_1446Patatin; COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641; KEGG: ssm:Spirs_3807 patatin; PFAM: Patatin/Phospholipase A2-related; SPTR: Putative membrane protein; [...]
fmt protein networkhttps://string-db.org/network/760011.Spico_1447Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
def protein networkhttps://string-db.org/network/760011.Spico_1448Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...]
AEC02653.1 protein networkhttps://string-db.org/network/760011.Spico_1449Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR002951:IPR011110:IPR000408; KEGG: aeh:Mlg_2687 regulator [...]
priA protein networkhttps://string-db.org/network/760011.Spico_1451Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its h [...]
AEC02655.1 protein networkhttps://string-db.org/network/760011.Spico_1452Phage SPO1 DNA polymerase-related protein; COGs: COG1573 Uracil-DNA glycosylase; InterPro IPR005273:IPR005122; KEGG: ssm:Spirs_1652 phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA gly [...]
truA protein networkhttps://string-db.org/network/760011.Spico_1453tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
acpS protein networkhttps://string-db.org/network/760011.Spico_1454Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
AEC02658.1 protein networkhttps://string-db.org/network/760011.Spico_1455YbbR family protein; InterPro IPR012505; KEGG: ssm:Spirs_1648 YbbR family protein; PFAM: YbbR-like; SPTR: Membrane associated protein; IMG reference gene:2503957768; PFAM: YbbR-like protein.
dacA protein networkhttps://string-db.org/network/760011.Spico_1456Conserved hypothetical protein CHP00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteri [...]
AEC02660.1 protein networkhttps://string-db.org/network/760011.Spico_1457Peptidase M16 domain protein; COGs: COG1026 Zn-dependent peptidase insulinase-like; InterPro IPR011765:IPR007863:IPR013578; KEGG: ssm:Spirs_3660 peptidase M16C associated domain protein; PFAM: Pe [...]
AEC02661.1 protein networkhttps://string-db.org/network/760011.Spico_1458COGs: COG0584 Glycerophosphoryl diester phosphodiesterase; InterPro IPR004129; KEGG: ssm:Spirs_3903 glycerophosphoryl diester phosphodiesterase; PFAM: Glycerophosphoryl diester phosphodiesterase; [...]
AEC02662.1 protein networkhttps://string-db.org/network/760011.Spico_1459KEGG: tde:TDE0730 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957772.
AEC02663.1 protein networkhttps://string-db.org/network/760011.Spico_1460KEGG: yen:YE4032 hypothetical protein; SPTR: Cell envelope proteinase; IMG reference gene:2503957773.
AEC02664.1 protein networkhttps://string-db.org/network/760011.Spico_1461Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
AEC02665.1 protein networkhttps://string-db.org/network/760011.Spico_1462KEGG: ere:EUBREC_3205 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957775.
AEC02666.1 protein networkhttps://string-db.org/network/760011.Spico_1463Hypothetical protein; KEGG: ctt:CtCNB1_3098 TRAP dicarboxylate transporter, DctM subunit; SPTR: TRAP dicarboxylate transporter, DctM subunit; IMG reference gene:2503957776.
AEC02667.1 protein networkhttps://string-db.org/network/760011.Spico_1464Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR011110:IPR000408; KEGG: aeh:Mlg_2688 regulator of chromos [...]
AEC02668.1 protein networkhttps://string-db.org/network/760011.Spico_1465Hypothetical protein; KEGG: isc:IscW_ISCW015120 GTP-binding protein, putative; SPTR: GTP-binding protein, putative; IMG reference gene:2503957778.
AEC02669.1 protein networkhttps://string-db.org/network/760011.Spico_1466KEGG: hoh:Hoch_6421 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957779.
AEC02672.1 protein networkhttps://string-db.org/network/760011.Spico_1469KEGG: mav:MAV_4833 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957782.
AEC02673.1 protein networkhttps://string-db.org/network/760011.Spico_1470Hypothetical protein; KEGG: mka:MK1527 formylmethanofuran dehydrogenase subunit B, selenocysteine containing; SPTR: Putative ferrichrome transport ATP-binding protein FhuC; IMG reference gene:250 [...]
rex-2 protein networkhttps://string-db.org/network/760011.Spico_1471Redox-sensing transcriptional repressor rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
metAA protein networkhttps://string-db.org/network/760011.Spico_1472Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
AEC02676.1 protein networkhttps://string-db.org/network/760011.Spico_1473COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235:IPR000277; KEGG: cpy:Cphy_0010 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism, pyridoxal phosphate-de [...]
AEC02677.1 protein networkhttps://string-db.org/network/760011.Spico_1474Endonuclease/exonuclease/phosphatase; InterPro IPR005135; KEGG: ssm:Spirs_3694 endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/pho [...]
AEC02678.1 protein networkhttps://string-db.org/network/760011.Spico_1475KEGG: sta:STHERM_c14020 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957788.
clpP-2 protein networkhttps://string-db.org/network/760011.Spico_1476ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the de [...]
AEC02680.1 protein networkhttps://string-db.org/network/760011.Spico_1477KEGG: tde:TDE1234 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957790.
AEC02681.1 protein networkhttps://string-db.org/network/760011.Spico_1478KEGG: tde:TDE1234 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957791.
AEC02682.1 protein networkhttps://string-db.org/network/760011.Spico_1479KEGG: tde:TDE1234 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957792.
AEC02683.1 protein networkhttps://string-db.org/network/760011.Spico_1480MgtC/SapB transporter; COGs: COG1285 membrane protein; InterPro IPR003416; KEGG: snb:SP670_2012 MgtC/SapB transporter; PFAM: MgtC/SapB transporter; SPTR: MgtC/SapB transporter; IMG reference gene [...]
era protein networkhttps://string-db.org/network/760011.Spico_1481GTP-binding protein Era-like-protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and [...]
AEC02685.1 protein networkhttps://string-db.org/network/760011.Spico_1482ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: cwo:Cwoe_1260 ROK family protein; PFAM: ROK; SPTR: ROK family protein; IMG reference gene:25039 [...]
AEC02686.1 protein networkhttps://string-db.org/network/760011.Spico_1483Glycoside hydrolase family 57; InterPro IPR004300; KEGG: pst:PSPTO_4203 polysaccharide deacetylase family protein; PFAM: Glycoside hydrolase, family 57, N-terminal; SPTR: Polysaccharide deacetyla [...]
AEC02687.1 protein networkhttps://string-db.org/network/760011.Spico_1484COGs: COG2159 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: tle:Tlet_1114 amidohydrolase 2; PFAM: Amidohydrolase 2; SPTR: Amidohydrolase 2; IMG reference gene:250395 [...]
AEC02688.1 protein networkhttps://string-db.org/network/760011.Spico_1485Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: atu:Atu4652 ABC transporter, membrane spa [...]
AEC02689.1 protein networkhttps://string-db.org/network/760011.Spico_1486Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: atu:Atu4653 ABC transporter, membrane s [...]
AEC02690.1 protein networkhttps://string-db.org/network/760011.Spico_1487Carbohydrate ABC transporter substrate-binding protein, CUT1 family; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: tle:Tlet_1117 extracellular sol [...]
AEC02691.1 protein networkhttps://string-db.org/network/760011.Spico_1488COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845; KEGG: chy:CHY_2012 phosphoglucosamine mutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase [...]
lysS protein networkhttps://string-db.org/network/760011.Spico_1489COGs: COG1384 Lysyl-tRNA synthetase (class I); HAMAP: Lysyl-tRNA synthetase, class I, archaeal-type; InterPro IPR002904:IPR020754:IPR020756; KEGG: ssm:Spirs_3699 lysyl-tRNA synthetase; PFAM: Lysy [...]
rlpA protein networkhttps://string-db.org/network/760011.Spico_1490Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
AEC02694.1 protein networkhttps://string-db.org/network/760011.Spico_1491Hypothetical protein; KEGG: lbf:LBF_1543 cytoplasmic membrane protein, ImpL63; SPTR: Macrolide export ATP-binding/permease protein MacB; IMG reference gene:2503957804.
valS-3 protein networkhttps://string-db.org/network/760011.Spico_1492valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
AEC02696.1 protein networkhttps://string-db.org/network/760011.Spico_1493Major facilitator superfamily MFS_1; InterPro IPR011701; KEGG: cbt:CLH_2235 permease of the major facilitator superfamily; PFAM: Major facilitator superfamily MFS-1; SPTR: Possible MDR-type perme [...]
AEC02697.1 protein networkhttps://string-db.org/network/760011.Spico_1494Protein of unknown function DUF990; COGs: COG4587 ABC-type uncharacterized transport system permease component; InterPro IPR010390; KEGG: fnu:FN0879 ABC transporter integral membrane protein; PFA [...]
AEC02698.1 protein networkhttps://string-db.org/network/760011.Spico_1495ABC transporter related protein; COGs: COG4586 ABC-type uncharacterized transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: fnu:FN0880 ABC transporter ATP-binding protein; PFAM [...]
AEC02699.1 protein networkhttps://string-db.org/network/760011.Spico_1496Protein of unknown function DUF990; COGs: COG3694 ABC-type uncharacterized transport system permease component; InterPro IPR010390; KEGG: fnu:FN0881 ABC transporter integral membrane protein; PFA [...]
AEC02700.1 protein networkhttps://string-db.org/network/760011.Spico_1497COGs: COG2818 3-methyladenine DNA glycosylase; InterPro IPR005019; KEGG: vpr:Vpar_1788 methyladenine glycosylase; PFAM: Methyladenine glycosylase; PRIAM: DNA-3-methyladenine glycosylase I; SPTR: [...]
AEC02701.1 protein networkhttps://string-db.org/network/760011.Spico_1498DNA helicase; COGs: COG1112 Superfamily I DNA and RNA helicase and helicase subunits; KEGG: ere:EUBREC_0650 DNA helicase; SPTR: Putative DNA helicase; IMG reference gene:2503957812; PFAM: UvrD/RE [...]
AEC02702.1 protein networkhttps://string-db.org/network/760011.Spico_1499Filamentation induced by cAMP protein Fic; COGs: COG3177 conserved hypothetical protein; InterPro IPR003812; KEGG: clo:HMPREF0868_0124 Fic family protein; PFAM: Filamentation induced by cAMP/deat [...]
AEC02703.1 protein networkhttps://string-db.org/network/760011.Spico_1500Hypothetical protein; IMG reference gene:2503957814.
AEC02704.1 protein networkhttps://string-db.org/network/760011.Spico_1501LmbE family protein; COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: sus:Acid_1929 LmbE family protein; PFAM: N-acetylglucosaminyl phosphatidylinositol deace [...]
AEC02705.1 protein networkhttps://string-db.org/network/760011.Spico_1502NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to [...]
AEC02706.1 protein networkhttps://string-db.org/network/760011.Spico_1503NAD(P)(+) transhydrogenase-like protein; COGs: COG3288 NAD/NADP transhydrogenase alpha subunit; KEGG: lbf:LBF_0175 NAD(P)(+) transhydrogenase-like protein; SPTR: Proton-translocating transhydroge [...]
AEC02707.1 protein networkhttps://string-db.org/network/760011.Spico_1504NAD(P)(+) transhydrogenase (AB-specific); COGs: COG3288 NAD/NADP transhydrogenase alpha subunit; InterPro IPR007886:IPR007698; KEGG: abo:ABO_1329 pyridine nucleotide transhydrogenase A subunit; P [...]
AEC02708.1 protein networkhttps://string-db.org/network/760011.Spico_1505D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: amt:Amet_3747 FAD linked oxidase domain-containing protein; PFAM: FAD-lin [...]
AEC02709.1 protein networkhttps://string-db.org/network/760011.Spico_1506COGs: COG2025 Electron transfer flavoprotein alpha subunit; InterPro IPR014730:IPR014731; KEGG: amt:Amet_3748 electron transfer flavoprotein, alpha subunit-like protein; PFAM: Electron transfer f [...]
AEC02710.1 protein networkhttps://string-db.org/network/760011.Spico_1507COGs: COG2086 Electron transfer flavoprotein beta subunit; InterPro IPR014730; KEGG: amt:Amet_3749 electron transfer flavoprotein, alpha/beta-subunit-like protein; PFAM: Electron transfer flavopr [...]
AEC02711.1 protein networkhttps://string-db.org/network/760011.Spico_1508Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate ac [...]
AEC02712.1 protein networkhttps://string-db.org/network/760011.Spico_1509COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: eel:EUBELI_20516 phosphocarrier protein HPr; PFAM: Phosphotransferase system, phosphocarrier HPr protein; SP [...]
AEC02713.1 protein networkhttps://string-db.org/network/760011.Spico_1510Metalloenzyme domain protein; COGs: COG1015 Phosphopentomutase; InterPro IPR006124; KEGG: sfv:SFV_3385 putative mutase; PFAM: Metalloenzyme; SPTR: Phosphopentomutase; IMG reference gene:250395782 [...]
AEC02714.1 protein networkhttps://string-db.org/network/760011.Spico_1511Alanine racemase domain protein; COGs: COG3457 amino acid racemase; InterPro IPR001608; KEGG: thx:Thet_0218 alanine racemase domain-containing protein; PFAM: Alanine racemase, N-terminal; SPTR: P [...]
AEC02715.1 protein networkhttps://string-db.org/network/760011.Spico_1512KEGG: csh:Closa_2021 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957826; PFAM: Aminotransferase class-V.
AEC02716.1 protein networkhttps://string-db.org/network/760011.Spico_1513Aryldialkylphosphatase; COGs: COG1735 metal-dependent hydrolase with the TIM-barrel fold; InterPro IPR001559; KEGG: str:Sterm_0361 aryldialkylphosphatase; PFAM: Aryldialkylphosphatase; SPTR: Phos [...]
AEC02717.1 protein networkhttps://string-db.org/network/760011.Spico_1514KEGG: csh:Closa_2023 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957828; PFAM: Amidase.
AEC02718.1 protein networkhttps://string-db.org/network/760011.Spico_1515InterPro IPR019733; KEGG: ttm:Tthe_1693 protein of unknown function, YhfT; PFAM: Uncharacterised protein family YhfT; SPTR: Putative uncharacterized protein; IMG reference gene:2503957829; PFAM: [...]
AEC02719.1 protein networkhttps://string-db.org/network/760011.Spico_1516KEGG: xbo:XBJ1_0132 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957830; PFAM: Protein of unknown function DUF2620.
AEC02720.1 protein networkhttps://string-db.org/network/760011.Spico_1517PRD domain protein; InterPro IPR011608; KEGG: sth:STH556 putative transcriptional antiterminator; PFAM: PRD; SPTR: Predicted protein; IMG reference gene:2503957831; PFAM: PRD domain.
AEC02721.1 protein networkhttps://string-db.org/network/760011.Spico_1518KEGG: thx:Thet_0211 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957832.
AEC02722.1 protein networkhttps://string-db.org/network/760011.Spico_1519Alcohol dehydrogenase; COGs: COG1979 Uncharacterized oxidoreductase Fe-dependent alcohol dehydrogenase family; InterPro IPR001670; KEGG: apa:APP7_1949 probable NADH-dependent butanol dehydrogenas [...]
AEC02723.1 protein networkhttps://string-db.org/network/760011.Spico_1520COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR003439; KEGG: ssm:Spirs_3268 ABC transporter related protein; PFAM: ABC transport [...]
AEC02724.1 protein networkhttps://string-db.org/network/760011.Spico_1521COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR003439; KEGG: ssm:Spirs_3269 ABC transporter related protein; PFAM: ABC transport [...]
AEC02725.1 protein networkhttps://string-db.org/network/760011.Spico_1522Regulatory protein MarR; InterPro IPR000835; KEGG: ssm:Spirs_3270 transcriptional regulator, MarR family; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SP [...]
AEC02726.1 protein networkhttps://string-db.org/network/760011.Spico_1523Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378:IPR011110:IPR000408; KEGG: aeh:Mlg_2687 regulator [...]
AEC02727.1 protein networkhttps://string-db.org/network/760011.Spico_1524Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378:IPR000408; KEGG: aeh:Mlg_2687 regulator of chromos [...]
AEC02728.1 protein networkhttps://string-db.org/network/760011.Spico_1525Cell wall/surface repeat protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378:IPR011110:IPR000408; KEGG: aeh:Mlg_2687 regulator of chromo [...]
AEC02729.1 protein networkhttps://string-db.org/network/760011.Spico_1526Domain of unknown function DUF1801; InterPro IPR014922; KEGG: gur:Gura_3522 hypothetical protein; PFAM: Protein of unknown function DUF1801; SPTR: Putative uncharacterized protein; IMG reference [...]
AEC02730.1 protein networkhttps://string-db.org/network/760011.Spico_1527COGs: COG1114 Branched-chain amino acid permease; InterPro IPR004685; KEGG: efa:EF0243 branched-chain amino acid transport system II carrier protein; PFAM: Branched-chain amino acid transport sys [...]
AEC02731.1 protein networkhttps://string-db.org/network/760011.Spico_1528Protein of unknown function DUF81; COGs: COG0730 permease; InterPro IPR002781; KEGG: cbt:CLH_3273 transporter; PFAM: Protein of unknown function DUF81; SPTR: Transporter; IMG reference gene:25039 [...]
AEC02732.1 protein networkhttps://string-db.org/network/760011.Spico_1529InterPro IPR006104:IPR006103; KEGG: cpy:Cphy_3081 glycoside hydrolase family protein; PFAM: Glycoside hydrolase, family 2, carbohydrate-binding; Glycoside hydrolase, family 2, TIM barrel; SPTR: G [...]
AEC02733.1 protein networkhttps://string-db.org/network/760011.Spico_1530Domain of unknown function DUF1961; InterPro IPR015305; KEGG: bld:BLi01374 YesU; PFAM: Protein of unknown function DUF1961; SPTR: YesU; IMG reference gene:2503957844; PFAM: Domain of unknown func [...]
AEC02734.1 protein networkhttps://string-db.org/network/760011.Spico_1531KEGG: cpy:Cphy_3080 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957845.
AEC02735.1 protein networkhttps://string-db.org/network/760011.Spico_1532Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: cpy:Cphy_0341 extracellular solute-binding protein; P [...]
AEC02736.1 protein networkhttps://string-db.org/network/760011.Spico_1533Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: cpy:Cphy_0340 binding-protein-dependent t [...]
AEC02737.1 protein networkhttps://string-db.org/network/760011.Spico_1534Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: cob:COB47_1870 binding-protein-d [...]
AEC02738.1 protein networkhttps://string-db.org/network/760011.Spico_1535COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR003439; KEGG: pjd:Pjdr2_0901 ABC transporter related; PFAM: ABC transporter-like; [...]
AEC02739.1 protein networkhttps://string-db.org/network/760011.Spico_1536COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR003439; KEGG: pjd:Pjdr2_0902 ABC transporter related; PFAM: ABC transporter-like; [...]
AEC02740.1 protein networkhttps://string-db.org/network/760011.Spico_1537Beta-phosphoglucomutase; COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR010972:IPR010976:IPR006402:IPR005834; KEGG: csh:Closa_0870 beta-phosphoglucomutase; PFAM: Haloacid dehalogenase-l [...]
AEC02741.1 protein networkhttps://string-db.org/network/760011.Spico_1538Kojibiose phosphorylase; COGs: COG1554 Trehalose and maltose hydrolase (possible phosphorylase); InterPro IPR005196:IPR005195:IPR005194; KEGG: gym:GYMC10_0477 glycoside hydrolase family 65 centra [...]
AEC02742.1 protein networkhttps://string-db.org/network/760011.Spico_1539Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: gym:GYMC10_0424 binding-protein-dependent [...]
AEC02743.1 protein networkhttps://string-db.org/network/760011.Spico_1540Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: gym:GYMC10_0423 binding-protein-depende [...]
AEC02744.1 protein networkhttps://string-db.org/network/760011.Spico_1541Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_0422 extracellular solute-binding protein [...]
AEC02745.1 protein networkhttps://string-db.org/network/760011.Spico_1542Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: gym:GYMC10_0421 transcriptional regulator, LacI family; PFAM: HTH transcripti [...]
AEC02746.1 protein networkhttps://string-db.org/network/760011.Spico_1543COGs: COG3830 ACT domain-containing protein; HAMAP: Uncharacterised protein family UPF0237, ACT domain-containing; InterPro IPR022986:IPR002912; KEGG: bde:BDP_1787 ACT domain-containing protein; [...]
AEC02747.1 protein networkhttps://string-db.org/network/760011.Spico_1544UPF0210 protein; COGs: COG2848 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0210; InterPro IPR007841; KEGG: cpy:Cphy_2797 hypothetical protein; PFAM: Uncharacterised p [...]
AEC02748.1 protein networkhttps://string-db.org/network/760011.Spico_1546COGs: COG5015 conserved hypothetical protein; InterPro IPR011576; KEGG: bpb:bpr_I1023 pyridoxamine 5'-phosphate oxidase family protein; PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding d [...]
AEC02749.1 protein networkhttps://string-db.org/network/760011.Spico_1547KEGG: bfr:BF3847 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957861.
AEC02750.1 protein networkhttps://string-db.org/network/760011.Spico_1548MATE efflux family protein; COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: cbk:CLL_A1589 Na+-driven multidrug efflux pump; PFAM: Multi antimicrobial extrusion protein; [...]
AEC02751.1 protein networkhttps://string-db.org/network/760011.Spico_1549Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodo [...]
AEC02752.1 protein networkhttps://string-db.org/network/760011.Spico_1550COGs: COG1882 Pyruvate-formate lyase; InterPro IPR005949:IPR004184:IPR001150; KEGG: efa:EF1613 formate acetyltransferase; PFAM: Pyruvate formate-lyase, PFL; Formate C-acetyltransferase glycine ra [...]
asnA protein networkhttps://string-db.org/network/760011.Spico_1551Aspartate-ammonia ligase; COGs: COG2502 Asparagine synthetase A; HAMAP: Aspartate--ammonia ligase; InterPro IPR004618; KEGG: pdi:BDI_3717 asparagine synthetase AsnA; PFAM: Aspartate--ammonia liga [...]
AEC02754.1 protein networkhttps://string-db.org/network/760011.Spico_1552HI0933 family protein; COGs: COG2081 flavoprotein; InterPro IPR004792; KEGG: mhu:Mhun_1926 HI0933-like protein; PFAM: Conserved hypothetical protein CHP00275, flavoprotein HI0933-like; SPTR: HI09 [...]
AEC02755.1 protein networkhttps://string-db.org/network/760011.Spico_1553NADPH-dependent FMN reductase; COGs: COG0431 flavoprotein; InterPro IPR005025; KEGG: cpy:Cphy_1114 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: NADPH-dependent FMN re [...]
AEC02756.1 protein networkhttps://string-db.org/network/760011.Spico_1554Hypothetical protein; InterPro IPR011493; KEGG: hwa:HQ1081A halomucin; SPTR: Halomucin; IMG reference gene:2503957868.
AEC02757.1 protein networkhttps://string-db.org/network/760011.Spico_1555COGs: COG2055 Malate/L-lactate dehydrogenase; InterPro IPR003767; KEGG: kol:Kole_0486 malate/L-lactate dehydrogenase; PFAM: Malate/L-lactate dehydrogenase; PRIAM: Malate dehydrogenase; SPTR: Mala [...]
AEC02758.1 protein networkhttps://string-db.org/network/760011.Spico_1556Transcriptional regulator, DeoR family; COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036; KEGG: pca:Pcar_0940 putative DeoR-type transcriptional regulato [...]
glpK protein networkhttps://string-db.org/network/760011.Spico_1557Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
fabV protein networkhttps://string-db.org/network/760011.Spico_1558Reductase; Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA); Belongs to the [...]
AEC02761.1 protein networkhttps://string-db.org/network/760011.Spico_1559Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; COGs: COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase; InterPro IPR013114; KEGG: sta:STHERM_c08550 b [...]
AEC02762.1 protein networkhttps://string-db.org/network/760011.Spico_15603-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
AEC02763.1 protein networkhttps://string-db.org/network/760011.Spico_15613-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cy [...]
AEC02764.1 protein networkhttps://string-db.org/network/760011.Spico_1562COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043:IPR020801; KEGG: sta:STHERM_c21550 hypothetical protein; PFAM: Acyl transferase; PRIAM: [Acyl-carrier-protein] S-malo [...]
AEC02765.1 protein networkhttps://string-db.org/network/760011.Spico_1563acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the car [...]
AEC02766.1 protein networkhttps://string-db.org/network/760011.Spico_1564Biotin carboxylase; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR005481:IPR005479:IPR005482; KEGG: sta:STHERM_c08570 pyruvate carboxylase subunit A; PFAM: Carbamoyl-p [...]
accD protein networkhttps://string-db.org/network/760011.Spico_1565acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrie [...]
accA protein networkhttps://string-db.org/network/760011.Spico_1566acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carr [...]
AEC02769.1 protein networkhttps://string-db.org/network/760011.Spico_1567Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: pdi:BDI_2255 acetyl-coenzyme A synthetase; PFAM: AMP-dependent synthetase/ligase; [...]
AEC02770.1 protein networkhttps://string-db.org/network/760011.Spico_1568Thioesterase superfamily protein; COGs: COG5496 thioesterase; KEGG: cob:COB47_1987 thioesterase superfamily protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957882.
AEC02771.1 protein networkhttps://string-db.org/network/760011.Spico_1569Major facilitator superfamily MFS_1; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: cbe:Cbei_0707 major facilitator transporter; PFAM: Major facilitator superfamily MFS-1; SPT [...]
tpx protein networkhttps://string-db.org/network/760011.Spico_1570Thiol peroxidase (atypical 2-Cys peroxiredoxin); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays [...]
AEC02773.1 protein networkhttps://string-db.org/network/760011.Spico_1571InterPro IPR013096; KEGG: sus:Acid_7125 cupin 2 domain-containing protein; PFAM: Cupin 2, conserved barrel; SPTR: Putative uncharacterized protein; IMG reference gene:2503957885; PFAM: Cupin doma [...]
AEC02774.1 protein networkhttps://string-db.org/network/760011.Spico_1572COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953; KEGG: ske:Sked_06460 succinate dehydrogenase/fumarate reductase flavoprotein subunit; PFAM: Fuma [...]
AEC02775.1 protein networkhttps://string-db.org/network/760011.Spico_15733-oxoacyl-(acyl-carrier-protein) reductase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR020842; KEGG: pac:PPA037 [...]
AEC02776.1 protein networkhttps://string-db.org/network/760011.Spico_1574NADH:flavin oxidoreductase/NADH oxidase; COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155; KEGG: trq:TRQ2_0516 NADH:flavin oxidoreductase/NADH oxidase; PFAM: [...]
AEC02777.1 protein networkhttps://string-db.org/network/760011.Spico_1575Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: tmt:Tmath_0260 transcriptional regulator, LacI family; PFAM: Periplasmic bind [...]
AEC02778.1 protein networkhttps://string-db.org/network/760011.Spico_1576Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: cpy:C [...]
AEC02779.1 protein networkhttps://string-db.org/network/760011.Spico_1577Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family; COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: dma:D [...]
AEC02780.1 protein networkhttps://string-db.org/network/760011.Spico_1578Inner-membrane translocator; COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: amt:Amet_2076 inner-membrane translocator; PFAM: ABC t [...]
AEC02781.1 protein networkhttps://string-db.org/network/760011.Spico_1579Inner-membrane translocator; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: amt:Amet_2075 inner-membrane translocator; PFAM: ABC [...]
AEC02782.1 protein networkhttps://string-db.org/network/760011.Spico_1580Extracellular ligand-binding receptor; COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: amt:Amet_2074 extracellular ligand-bindi [...]
AEC02783.1 protein networkhttps://string-db.org/network/760011.Spico_1581Methylglyoxal reductase (NADPH-dependent); COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR023210; KEGG: gtn:GTNG_0505 aldo/keto reductase family oxidoreductase [...]
AEC02784.1 protein networkhttps://string-db.org/network/760011.Spico_1582COGs: COG1692 conserved hypothetical protein; KEGG: ssm:Spirs_4037 hypothetical protein; SPTR: Metallophosphoesterase; manually curated; IMG reference gene:2503957896; TIGRFAM: metallophosphoeste [...]
AEC02785.1 protein networkhttps://string-db.org/network/760011.Spico_1583Protein of unknown function DUF1239; InterPro IPR010664; KEGG: apb:SAR116_1245 hypothetical protein; PFAM: Lipopolysccharide assembly, LptC-related; SPTR: OstA family protein; IMG reference gene: [...]
AEC02786.1 protein networkhttps://string-db.org/network/760011.Spico_1584KEGG: ssm:Spirs_4046 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957898; PFAM: Protein of unknown function (DUF1239).
AEC02787.1 protein networkhttps://string-db.org/network/760011.Spico_1585Fe(3+)-transporting ATPase; COGs: COG1137 ABC-type (unclassified) transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c21930 transporter; PFAM: ABC transporter-like; [...]
AEC02788.1 protein networkhttps://string-db.org/network/760011.Spico_1586COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: ssm:Spirs_4048 RNA polymerase, sigma 54 subunit, RpoN; PFAM: RNA [...]
AEC02789.1 protein networkhttps://string-db.org/network/760011.Spico_1587KEGG: ssm:Spirs_4049 ribosomal subunit interface protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957901; PFAM: Sigma 54 modulation protein / S30EA ribosomal protein; TIGRF [...]
hprK protein networkhttps://string-db.org/network/760011.Spico_1588Hpr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dep [...]
AEC02791.1 protein networkhttps://string-db.org/network/760011.Spico_1589COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: ssm:Spirs_4051 phosphotransferase system, phosphocarrier protein HPr; PFAM: Phosphotransferase system, phosp [...]
lexA protein networkhttps://string-db.org/network/760011.Spico_1590SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, R [...]
AEC02793.1 protein networkhttps://string-db.org/network/760011.Spico_1591COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR010372; KEGG: ssm:Spirs_4056 DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta; SPTR: Putative uncharacterized protein [...]
uvrC protein networkhttps://string-db.org/network/760011.Spico_1592UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible [...]
AEC02795.1 protein networkhttps://string-db.org/network/760011.Spico_1593KEGG: sta:STHERM_c17700 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957907.
thyX protein networkhttps://string-db.org/network/760011.Spico_1594Thymidylate synthase thyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofol [...]
AEC02797.1 protein networkhttps://string-db.org/network/760011.Spico_1595Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subuni [...]
AEC02798.1 protein networkhttps://string-db.org/network/760011.Spico_1596Extracellular solute-binding protein family 5; COGs: COG4166 ABC-type oligopeptide transport system periplasmic component; InterPro IPR000914; KEGG: ssm:Spirs_4114 extracellular solute-binding pr [...]
AEC02799.1 protein networkhttps://string-db.org/network/760011.Spico_1597COGs: COG1640 4-alpha-glucanotransferase; InterPro IPR003385; KEGG: ssm:Spirs_4115 4-alpha-glucanotransferase; PFAM: Glycoside hydrolase, family 77; PRIAM: 4-alpha-glucanotransferase; SPTR: 4-alp [...]
AEC02800.1 protein networkhttps://string-db.org/network/760011.Spico_1598COGs: COG1329 Transcriptional regulators similar to M. xanthus CarD; InterPro IPR003711; KEGG: ssm:Spirs_4116 transcriptional regulator, CarD family; PFAM: Transcription factor CarD; SPTR: Transc [...]
AEC02801.1 protein networkhttps://string-db.org/network/760011.Spico_1599COGs: COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; InterPro IPR001228; KEGG: ssm:Spirs_4117 4-diphosphocytidyl-2C-methyl-D-erythritolsynthas E; PFAM: 4-diphosphocytidyl-2C-methyl-D- [...]
ispF protein networkhttps://string-db.org/network/760011.Spico_16002-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid [...]
AEC02803.1 protein networkhttps://string-db.org/network/760011.Spico_1601KEGG: ssm:Spirs_4125 hypothetical protein; SPTR: Putative cytoplasmic protein; IMG reference gene:2503957915.
AEC02804.1 protein networkhttps://string-db.org/network/760011.Spico_1603COGs: COG3943 Virulence protein; KEGG: clo:HMPREF0868_1371 hypothetical protein; SPTR: Toxin-antitoxin system, toxin component, Fic family; IMG reference gene:2503957917.
fusA-2 protein networkhttps://string-db.org/network/760011.Spico_1604Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocat [...]
AEC02806.1 protein networkhttps://string-db.org/network/760011.Spico_1605COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043; KEGG: acl:ACL_1377 xanthine/uracil/vitamin C permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Xanthine/uracil/vitamin C permea [...]
AEC02807.1 protein networkhttps://string-db.org/network/760011.Spico_1606acyl-ACP thioesterase; InterPro IPR002864; KEGG: dvm:DvMF_1428 acyl-ACP thioesterase; PFAM: Acyl-ACP thioesterase; SPTR: Acyl-ACP thioesterase; IMG reference gene:2503957920; PFAM: Acyl-ACP thioe [...]
AEC02808.1 protein networkhttps://string-db.org/network/760011.Spico_1607COGs: COG3588 Fructose-1 6-bisphosphate aldolase; InterPro IPR000741; KEGG: fjo:Fjoh_0953 fructose-1,6-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase, class-I; SPTR: Fructose-bisphos [...]
AEC02809.1 protein networkhttps://string-db.org/network/760011.Spico_1608Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR000408; KEGG: aeh:Mlg_2687 regulator of chromosome conden [...]
AEC02810.1 protein networkhttps://string-db.org/network/760011.Spico_1609ABC transporter related protein; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: dfe:Dfer_5189 ABC transporter related; PFAM: ABC transport [...]
AEC02811.1 protein networkhttps://string-db.org/network/760011.Spico_1610KEGG: ssm:Spirs_3164 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957924.
AEC02812.1 protein networkhttps://string-db.org/network/760011.Spico_1611Transcriptional regulator, GntR family; COGs: COG1725 transcriptional regulator protein; InterPro IPR000524; KEGG: ssm:Spirs_3163 transcriptional regulator, GntR family; PFAM: HTH transcriptional [...]
AEC02813.1 protein networkhttps://string-db.org/network/760011.Spico_1612Hypothetical protein; IMG reference gene:2503957926.
AEC02814.1 protein networkhttps://string-db.org/network/760011.Spico_1613Glycoside hydrolase family 2 TIM barrel; COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104:IPR006102:IPR006103:IPR004199; KEGG: rca:Rcas_2493 beta-galactosidase; PFAM: Glyco [...]
AEC02815.1 protein networkhttps://string-db.org/network/760011.Spico_1615Alcohol dehydrogenase (NADP(+)); COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149:IPR020843; KEGG: clo:HMPREF0868_1158 GroES-like protein [...]
AEC02816.1 protein networkhttps://string-db.org/network/760011.Spico_1616Cobalamin synthesis protein P47K; COGs: COG0523 Putative GTPase (G3E family); InterPro IPR003495; KEGG: apv:Apar_1227 cobalamin synthesis protein P47K; PFAM: Cobalamin (vitamin B12) biosynthesis [...]
AEC02817.1 protein networkhttps://string-db.org/network/760011.Spico_1617COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786:IPR001544; KEGG: cac:CA_C1479 branched-chain amino acid aminotransferase; PFAM: Aminot [...]
AEC02818.1 protein networkhttps://string-db.org/network/760011.Spico_1619Regulatory protein TetR; InterPro IPR001647; KEGG: bha:BH0719 TetR/AcrR family transcriptional regulator; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcri [...]
AEC02819.1 protein networkhttps://string-db.org/network/760011.Spico_1620L-threonine ammonia-lyase; COGs: COG1171 Threonine dehydratase; InterPro IPR005789:IPR001926:IPR002912; KEGG: bvu:BVU_3892 threonine dehydratase; PFAM: Pyridoxal phosphate-dependent enzyme, beta [...]
AEC02820.1 protein networkhttps://string-db.org/network/760011.Spico_1621Nitrogen regulatory protein P-II; InterPro IPR002187; KEGG: chy:CHY_1194 PII family protein; SMART: Nitrogen regulatory protein PII; SPTR: Regulatory protein, P-II family; IMG reference gene:2503 [...]
AEC02821.1 protein networkhttps://string-db.org/network/760011.Spico_1622Glucokinase; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: tte:TTE0761 transcriptional regulator; PFAM: ROK; PRIAM: Glucokinase; SPTR: Putative uncharacterized p [...]
AEC02822.1 protein networkhttps://string-db.org/network/760011.Spico_1623Sugar isomerase (SIS); COGs: COG0279 Phosphoheptose isomerase; InterPro IPR001347; KEGG: csh:Closa_3796 sugar isomerase (SIS); PFAM: Sugar isomerase (SIS); SPTR: Putative uncharacterized protein; [...]
AEC02823.1 protein networkhttps://string-db.org/network/760011.Spico_1624Two component transcriptional regulator, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR000005:IPR01806 [...]
AEC02824.1 protein networkhttps://string-db.org/network/760011.Spico_1625Integral membrane sensor signal transduction histidine kinase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR010559:IPR003594; KEGG: ssm:Spirs_2648 integr [...]
AEC02825.1 protein networkhttps://string-db.org/network/760011.Spico_1626COGs: COG1129 ABC-type sugar transport system ATPase component; KEGG: ssm:Spirs_2647 monosaccharide-transporting ATPase; SPTR: Putative uncharacterized protein; IMG reference gene:2503957940.
rbsA protein networkhttps://string-db.org/network/760011.Spico_1627Monosaccharide ABC transporter ATP-binding protein, CUT2 family; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Bel [...]
AEC02827.1 protein networkhttps://string-db.org/network/760011.Spico_1628Monosaccharide ABC transporter membrane protein, CUT2 family; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: ssm:Spirs [...]
AEC02828.1 protein networkhttps://string-db.org/network/760011.Spico_1629Monosaccharide ABC transporter substrate-binding protein, CUT2 family; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: ssm:Spirs_2644 periplasmic bi [...]
AEC02829.1 protein networkhttps://string-db.org/network/760011.Spico_1630Lipolytic protein G-D-S-L family; InterPro IPR001087; KEGG: bld:BLi04100 hypothetical protein; PFAM: Lipase, GDSL; SPTR: Putative uncharacterized protein; IMG reference gene:2503957944; PFAM: GDS [...]
AEC02830.1 protein networkhttps://string-db.org/network/760011.Spico_1631Phosphoglycerate mutase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: ssm:Spirs_1093 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SMART: Hist [...]
AEC02831.1 protein networkhttps://string-db.org/network/760011.Spico_1632Putative ABC transporter permease; COGs: COG4866 conserved hypothetical protein; KEGG: sta:STHERM_c02850 putative ABC transporter permease; SPTR: Putative ABC transporter, permease protein; IMG r [...]
AEC02832.1 protein networkhttps://string-db.org/network/760011.Spico_1634InterPro IPR000073; KEGG: kko:Kkor_1814 alpha/beta hydrolase fold protein; PFAM: Alpha/beta hydrolase fold-1; SPTR: Hydrolase, alpha/beta domain protein; IMG reference gene:2503957948; PFAM: X-Pr [...]
AEC02833.1 protein networkhttps://string-db.org/network/760011.Spico_1635COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR010140:IPR004013; KEGG: ssm:Spirs_0453 histidinol phosphate phosphatase HisJ family; PFAM: PHP, C-termina [...]
AEC02834.1 protein networkhttps://string-db.org/network/760011.Spico_1636Transcriptional regulator, TetR family; COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: hor:Hore_14700 transcriptional regulator, TetR family; PFAM: Transcription regulator, Te [...]
AEC02835.1 protein networkhttps://string-db.org/network/760011.Spico_1637Calcium-translocating P-type ATPase, PMCA-type; COGs: COG0474 Cation transport ATPase; InterProIPR006408:IPR001757:IPR004014:IPR008250:IPR 005834:IPR006068; KEGG: swo:Swol_0623 cation transportin [...]
AEC02836.1 protein networkhttps://string-db.org/network/760011.Spico_1638KEGG: fjo:Fjoh_3952 hypothetical protein; SPTR: Conserved repeat domain protein; IMG reference gene:2503957952.
AEC02837.1 protein networkhttps://string-db.org/network/760011.Spico_1639KEGG: bfr:BF3846 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957953.
AEC02838.1 protein networkhttps://string-db.org/network/760011.Spico_1640KEGG: bfr:BF3847 hypothetical protein; SPTR: Putative lipoprotein; IMG reference gene:2503957954.
AEC02839.1 protein networkhttps://string-db.org/network/760011.Spico_1641Transposase IS4 family protein; COGs: COG5421 Transposase; InterPro IPR002559; KEGG: cob:COB47_1677 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family prote [...]
AEC02840.1 protein networkhttps://string-db.org/network/760011.Spico_1642Transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792; KEGG: ssm:Spirs_3043 transcripti [...]
ldh protein networkhttps://string-db.org/network/760011.Spico_1643L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
AEC02842.1 protein networkhttps://string-db.org/network/760011.Spico_1644Periplasmic binding protein/LacI transcriptional regulator; COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: cpy:Cphy_2012 periplasmic binding protein/LacI transcription [...]
AEC02843.1 protein networkhttps://string-db.org/network/760011.Spico_1645Monosaccharide ABC transporter membrane protein, CUT2 family; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: cpy:Cphy_ [...]
AEC02844.1 protein networkhttps://string-db.org/network/760011.Spico_1646Monosaccharide ABC transporter ATP-binding protein, CUT2 family; COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: cpy:Cphy_2010 ABC transporter [...]
AEC02845.1 protein networkhttps://string-db.org/network/760011.Spico_1647Rhamnulokinase; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484; KEGG: gym:GYMC10_3922 carbohydrate kinase, FGGY-like protein; PFAM: Carbohydrate kinase, FGGY, N-terminal; [...]
AEC02846.1 protein networkhttps://string-db.org/network/760011.Spico_1648Alcohol dehydrogenase zinc-binding domain protein; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: csc:Csac_0869 alcohol dehydrog [...]
AEC02847.1 protein networkhttps://string-db.org/network/760011.Spico_16493-oxoacyl-(acyl-carrier-protein) reductase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: sta:STHERM_c08270 hy [...]
AEC02848.1 protein networkhttps://string-db.org/network/760011.Spico_1650KEGG: sta:STHERM_c08260 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957964.
AEC02849.1 protein networkhttps://string-db.org/network/760011.Spico_1651COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR001017:IPR005475:IPR005476; KEGG: sta:STHERM_c08250 putative deh [...]
AEC02850.1 protein networkhttps://string-db.org/network/760011.Spico_1652COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR006258:IPR013027:IPR004099; KEGG: csc:Csac_0873 dihydrolipoamide dehydrogenase; PFAM: [...]
AEC02851.1 protein networkhttps://string-db.org/network/760011.Spico_1653Dihydrolipoyllysine-residue acetyltransferase; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR004167:IPR001078; K [...]
AEC02852.1 protein networkhttps://string-db.org/network/760011.Spico_1654Transcriptional regulator, DeoR family; COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036; KEGG: sta:STHERM_c08230 transcriptional regulatory protein; PFA [...]
AEC02853.1 protein networkhttps://string-db.org/network/760011.Spico_1655L-rhamnose 1-epimerase; Involved in the anomeric conversion of L-rhamnose.
AEC02854.1 protein networkhttps://string-db.org/network/760011.Spico_1656Inner-membrane translocator; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: sta:STHERM_c08350 transporter; PFAM: ABC t [...]
AEC02855.1 protein networkhttps://string-db.org/network/760011.Spico_1657Inner-membrane translocator; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: oan:Oant_3568 monosaccharide-transporting [...]
rbsA-2 protein networkhttps://string-db.org/network/760011.Spico_1658Monosaccharide-transporting ATPase; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter s [...]
AEC02857.1 protein networkhttps://string-db.org/network/760011.Spico_1659Rhamnose-binding protein; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR013459; KEGG: sta:STHERM_c08320 transporter; SPTR: Transporter; TIGRFAM: Rhamnose ABC tr [...]
AEC02858.1 protein networkhttps://string-db.org/network/760011.Spico_1660Class II aldolase/adducin family protein; COGs: COG3347 conserved hypothetical protein; InterPro IPR001303; KEGG: sta:STHERM_c08370 short chain dehydrogenase; PFAM: Class II aldolase/adducin, N-t [...]
rhaA protein networkhttps://string-db.org/network/760011.Spico_1661COGs: COG4806 L-rhamnose isomerase; InterPro IPR009308; KEGG: csc:Csac_0876 L-rhamnose isomerase; PFAM: Rhamnose isomerase; PRIAM: L-rhamnose isomerase; SPTR: L-rhamnose isomerase; IMG reference [...]
AEC02860.1 protein networkhttps://string-db.org/network/760011.Spico_1662Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR003313:IPR000005:IPR018060; KEGG: rba:RB680 L-rhamnose operon transcriptional ac [...]
AEC02861.1 protein networkhttps://string-db.org/network/760011.Spico_1663Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: smd:Smed_4315 periplasmic binding protein/LacI transcriptional regulator; PFA [...]
AEC02862.1 protein networkhttps://string-db.org/network/760011.Spico_1664RbsD or FucU transport; COGs: COG4154 Fucose dissimilation pathway protein FucU; InterPro IPR007721; KEGG: pjd:Pjdr2_1349 RbsD or FucU transport; PFAM: D-ribose pyranase RbsD/L-fucose mutarotase [...]
fucI protein networkhttps://string-db.org/network/760011.Spico_1665L-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose.
AEC02864.1 protein networkhttps://string-db.org/network/760011.Spico_1666Major facilitator superfamily MFS_1; COGs: COG0738 Fucose permease; InterPro IPR011701; KEGG: gym:GYMC10_2567 major facilitator superfamily MFS_1; PFAM: Major facilitator superfamily MFS-1; SPTR: [...]
AEC02865.1 protein networkhttps://string-db.org/network/760011.Spico_1667KEGG: sta:STHERM_c21820 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957981; PFAM: Protein of unknown function (DUF1312).
AEC02866.1 protein networkhttps://string-db.org/network/760011.Spico_1668Periplasmic solute binding protein; COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006127; KEGG: ccu:Ccur_04310 ABC-type metal ion transport [...]
AEC02867.1 protein networkhttps://string-db.org/network/760011.Spico_1669KEGG: ssm:Spirs_0502 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957983.
AEC02868.1 protein networkhttps://string-db.org/network/760011.Spico_1670Monosaccharide ABC transporter membrane protein, CUT2 family; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: aco:Amico [...]
AEC02869.1 protein networkhttps://string-db.org/network/760011.Spico_1671Monosaccharide ABC transporter membrane protein, CUT2 family; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: ssm:Spirs [...]
AEC02870.1 protein networkhttps://string-db.org/network/760011.Spico_1672Monosaccharide ABC transporter ATP-binding protein, CUT2 family; COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: ssm:Spirs_0505 ABC transporter [...]
AEC02871.1 protein networkhttps://string-db.org/network/760011.Spico_1673KEGG: ssm:Spirs_0506 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957987.
AEC02874.1 protein networkhttps://string-db.org/network/760011.Spico_1676RNA methyltransferase, TrmH family, group 3; COGs: COG0566 rRNA methylase; InterPro IPR004441:IPR013123:IPR001537; KEGG: ssm:Spirs_3194 RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRN [...]
dnaJ protein networkhttps://string-db.org/network/760011.Spico_1677Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an [...]
dnaK protein networkhttps://string-db.org/network/760011.Spico_1678Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
grpE protein networkhttps://string-db.org/network/760011.Spico_1679Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleot [...]
AEC02878.1 protein networkhttps://string-db.org/network/760011.Spico_1680COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302; KEGG: tde:TDE2446 malate dehydrogenase; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; PRIAM: Malate dehydrogenase (oxaloacet [...]
AEC02879.1 protein networkhttps://string-db.org/network/760011.Spico_1681Hypothetical protein; InterPro IPR011493; KEGG: azl:AZL_e00660 filamentous haemagglutinin outer membrane protein; SPTR: Filamentous haemagglutinin outer membrane protein; IMG reference gene:25039 [...]
AEC02880.1 protein networkhttps://string-db.org/network/760011.Spico_1682Hypothetical protein; KEGG: nvi:100119134 similar to conserved hypothetical protein; SPTR: GL17626; IMG reference gene:2503957996.
AEC02881.1 protein networkhttps://string-db.org/network/760011.Spico_1683Haloacid dehalogenase domain protein hydrolase; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834; KEGG: ssm:Spirs_3201 haloacid dehalogenase domain protein hydrolase; PFAM: Haloacid [...]
der protein networkhttps://string-db.org/network/760011.Spico_1684GTP-binding protein engA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) G [...]
AEC02883.1 protein networkhttps://string-db.org/network/760011.Spico_1685Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate ac [...]
AEC02884.1 protein networkhttps://string-db.org/network/760011.Spico_1686Lipoprotein LpqB, GerMN domain protein; InterPro IPR019606; KEGG: sti:Sthe_0621 spore germination protein-like protein; PFAM: GerMN domain; SMART: GerMN domain; SPTR: Putative uncharacterized pro [...]
AEC02885.1 protein networkhttps://string-db.org/network/760011.Spico_1687COGs: COG1189 rRNA methylase; InterPro IPR004538:IPR002877; KEGG: sta:STHERM_c13010 hemolysin; PFAM: Ribosomal RNA methyltransferase RrmJ/FtsJ; SPTR: Hemolysin; TIGRFAM: Haemolysin A; IMG referen [...]
AEC02886.1 protein networkhttps://string-db.org/network/760011.Spico_1688COGs: COG1692 conserved hypothetical protein; InterPro IPR005235:IPR004843; KEGG: ssm:Spirs_3213 Ser/Thr protein phosphatase family protein; PFAM: Metallo-dependent phosphatase; SPTR: Putative un [...]
rny protein networkhttps://string-db.org/network/760011.Spico_16892,3 cyclic-nucleotide 2-phosphodiesterase; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
rplQ protein networkhttps://string-db.org/network/760011.Spico_1690COGs: COG0203 Ribosomal protein L17; HAMAP: Ribosomal protein L17; InterPro IPR000456; KEGG: ssm:Spirs_0981 ribosomal protein L17; PFAM: Ribosomal protein L17; SPTR: 50S ribosomal protein L17; TI [...]
rpoA protein networkhttps://string-db.org/network/760011.Spico_1691DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpsD protein networkhttps://string-db.org/network/760011.Spico_1692SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpsK protein networkhttps://string-db.org/network/760011.Spico_1693SSU ribosomal protein S11P; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belo [...]
rpsM protein networkhttps://string-db.org/network/760011.Spico_1694SSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L [...]
rpmJ protein networkhttps://string-db.org/network/760011.Spico_1695HAMAP: Ribosomal protein L36; InterPro IPR000473; KEGG: ssm:Spirs_0976 ribosomal protein L36; PFAM: Ribosomal protein L36; SPTR: 50S ribosomal protein L36; TIGRFAM: Ribosomal protein L36; IMG ref [...]
secY protein networkhttps://string-db.org/network/760011.Spico_1696Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral [...]
rplO protein networkhttps://string-db.org/network/760011.Spico_1697LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
rpmD protein networkhttps://string-db.org/network/760011.Spico_1698LSU ribosomal protein L30P; InterPro IPR005996:IPR016082; KEGG: llm:llmg_2363 50S ribosomal protein L30; PFAM: Ribosomal protein L30, ferredoxin-like fold domain; SPTR: 50S ribosomal protein L30; [...]
rpsE protein networkhttps://string-db.org/network/760011.Spico_1699SSU ribosomal protein S5P; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 fa [...]
rplR protein networkhttps://string-db.org/network/760011.Spico_1700LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuber [...]
rplF protein networkhttps://string-db.org/network/760011.Spico_1701LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the [...]
rpsH protein networkhttps://string-db.org/network/760011.Spico_1702SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to [...]
rpsZ protein networkhttps://string-db.org/network/760011.Spico_1703SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
rplE protein networkhttps://string-db.org/network/760011.Spico_1704LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberanc [...]
rplX protein networkhttps://string-db.org/network/760011.Spico_1705LSU ribosomal protein L24P; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
rplN protein networkhttps://string-db.org/network/760011.Spico_1706LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rpsQ protein networkhttps://string-db.org/network/760011.Spico_1707SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rpmC protein networkhttps://string-db.org/network/760011.Spico_1708LSU ribosomal protein L29P; InterPro IPR001854; KEGG: ssm:Spirs_0963 ribosomal protein L29; PFAM: Ribosomal protein L29; SPTR: 50S ribosomal protein L29; TIGRFAM: Ribosomal protein L29; IMG refer [...]
rplP protein networkhttps://string-db.org/network/760011.Spico_1709LSU ribosomal protein L16P; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpsC protein networkhttps://string-db.org/network/760011.Spico_1710SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplV protein networkhttps://string-db.org/network/760011.Spico_1711LSU ribosomal protein L22P; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wa [...]
rpsS protein networkhttps://string-db.org/network/760011.Spico_1712SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplB protein networkhttps://string-db.org/network/760011.Spico_1713LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It [...]
rplW protein networkhttps://string-db.org/network/760011.Spico_1714Ribosomal protein L25/L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main dock [...]
rplD protein networkhttps://string-db.org/network/760011.Spico_1715LSU ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
rplC protein networkhttps://string-db.org/network/760011.Spico_1716LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ri [...]
rpsJ protein networkhttps://string-db.org/network/760011.Spico_1717SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
tuf protein networkhttps://string-db.org/network/760011.Spico_1718Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
rpsG protein networkhttps://string-db.org/network/760011.Spico_1719SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit int [...]
rpsL protein networkhttps://string-db.org/network/760011.Spico_1720SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S a [...]
rpoC protein networkhttps://string-db.org/network/760011.Spico_1721DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/760011.Spico_1722DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplL protein networkhttps://string-db.org/network/760011.Spico_1723LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bact [...]
rplJ protein networkhttps://string-db.org/network/760011.Spico_172450S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal prot [...]
rplA protein networkhttps://string-db.org/network/760011.Spico_1725LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplK protein networkhttps://string-db.org/network/760011.Spico_1726LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
nusG protein networkhttps://string-db.org/network/760011.Spico_1727Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination.
secE protein networkhttps://string-db.org/network/760011.Spico_1728Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
rpmG protein networkhttps://string-db.org/network/760011.Spico_1729HAMAP: Ribosomal protein L33; InterPro IPR001705; KEGG: ssm:Spirs_0942 ribosomal protein L33; PFAM: Ribosomal protein L33; SPTR: 50S ribosomal protein L33; TIGRFAM: Ribosomal protein L33; IMG ref [...]
AEC02928.1 protein networkhttps://string-db.org/network/760011.Spico_1730HAD-superfamily hydrolase, subfamily IIA; COGs: COG0647 sugar phosphatase of the HAD superfamily; InterPro IPR006357:IPR005834; KEGG: ssm:Spirs_3233 HAD-superfamily hydrolase, subfamily IIA; PFAM [...]
AEC02929.1 protein networkhttps://string-db.org/network/760011.Spico_1731COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: sta:STHERM_c07390 carbamoyl-phosphate synthase large [...]
carA protein networkhttps://string-db.org/network/760011.Spico_1732COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR006274:IPR002474:IPR000991; KEGG: ssm:Spirs_3538 carbamoyl-phosphate synthase, small subunit; PFAM: Glutamine amidotransferase [...]
AEC02931.1 protein networkhttps://string-db.org/network/760011.Spico_1733Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378:IPR011110:IPR000408; KEGG: aeh:Mlg_2687 regulator [...]
AEC02932.1 protein networkhttps://string-db.org/network/760011.Spico_1734InterPro IPR012480; KEGG: csh:Closa_4172 heparinase II/III family protein; PFAM: Heparinase II/III-like; SPTR: Putative uncharacterized protein; IMG reference gene:2503958050; PFAM: Heparinase II [...]
AEC02933.1 protein networkhttps://string-db.org/network/760011.Spico_1735Glycosyl hydrolase family 88; InterPro IPR010905; KEGG: rlg:Rleg_5051 glycosyl hydrolase family 88; PFAM: Glycosyl hydrolase, family 88; SPTR: Glycosyl hydrolase family 88; IMG reference gene:250 [...]
AEC02934.1 protein networkhttps://string-db.org/network/760011.Spico_1736Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: avi:Avi_7346 ABC transporter membrane spa [...]
AEC02935.1 protein networkhttps://string-db.org/network/760011.Spico_1737Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: rle:pRL120664 putative permease compone [...]
AEC02936.1 protein networkhttps://string-db.org/network/760011.Spico_1738Hypothetical protein; IMG reference gene:2503958054.
AEC02937.1 protein networkhttps://string-db.org/network/760011.Spico_1739Carbohydrate ABC transporter substrate-binding protein, CUT1 family; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: rec:RHECIAT_PC0000519 putative [...]
AEC02938.1 protein networkhttps://string-db.org/network/760011.Spico_1740Integral membrane sensor signal transduction histidine kinase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR010559:IPR003594; KEGG: csh:Closa_1 [...]
AEC02939.1 protein networkhttps://string-db.org/network/760011.Spico_1741Two component transcriptional regulator, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR000005:IPR01806 [...]
AEC02940.1 protein networkhttps://string-db.org/network/760011.Spico_1742InterPro IPR012480; KEGG: csh:Closa_1714 heparinase II/III family protein; PFAM: Heparinase II/III-like; SPTR: Putative uncharacterized protein; IMG reference gene:2503958058; PFAM: Heparinase II [...]
AEC02941.1 protein networkhttps://string-db.org/network/760011.Spico_1743KEGG: ret:RHE_PF00314 hypothetical protein; SPTR: Hypothetical conserved protein; IMG reference gene:2503958059.
AEC02942.1 protein networkhttps://string-db.org/network/760011.Spico_1744holo-ACP synthase CitX; COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase; InterPro IPR005551:IPR002736; KEGG: aat:D11S_0857 apo-citrate lyase phosphoribosyl-dephospho-CoA transferase/2-(5 [...]
AEC02943.1 protein networkhttps://string-db.org/network/760011.Spico_1745Citrate lyase ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.
AEC02944.1 protein networkhttps://string-db.org/network/760011.Spico_1746Membrane protein AbrB duplication; COGs: COG3180 Putative ammonia monooxygenase; InterPro IPR017516:IPR007820; KEGG: sds:SDEG_0995 putative ammonia monooxygenase; PFAM: Putative ammonia monooxyge [...]
AEC02945.1 protein networkhttps://string-db.org/network/760011.Spico_1747citrate/H+ symporter, CitMHS family; COGs: COG2851 H+/citrate symporter; InterPro IPR014738:IPR004680; KEGG: lsa:LSA1232 citrate:Mg(2+)(H+) symporter; PFAM: Divalent ion symporter; SPTR: Citrate: [...]
AEC02946.1 protein networkhttps://string-db.org/network/760011.Spico_1748COGs: COG3051 Citrate lyase alpha subunit; InterPro IPR006472; KEGG: afn:Acfer_0408 citrate lyase, alpha subunit; PFAM: Citrate lyase, alpha subunit; PRIAM: Citrate CoA-transferase; SPTR: Citrate [...]
AEC02947.1 protein networkhttps://string-db.org/network/760011.Spico_1749COGs: COG2301 Citrate lyase beta subunit; InterPro IPR005000; KEGG: afn:Acfer_0409 citrate (pro-3S)-lyase; PFAM: Aldehyde-lyase domain; PRIAM: Citryl-CoA lyase; SPTR: Citrate lyase, beta subunit; [...]
citD protein networkhttps://string-db.org/network/760011.Spico_1750Citrate lyase acyl carrier protein; Covalent carrier of the coenzyme of citrate lyase.
AEC02949.1 protein networkhttps://string-db.org/network/760011.Spico_1751Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: cac:CA_C1046 LysR family transcriptional regulator; PFAM: HTH transcriptional [...]
AEC02950.1 protein networkhttps://string-db.org/network/760011.Spico_1752Manganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase f [...]
AEC02951.1 protein networkhttps://string-db.org/network/760011.Spico_1753Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR000408; KEGG: aeh:Mlg_2687 regulator of chromosome conden [...]
AEC02952.1 protein networkhttps://string-db.org/network/760011.Spico_1754Hypothetical protein; KEGG: bmq:BMQ_1790 putative secreted protein; SPTR: Putative secreted protein; IMG reference gene:2503958070.
AEC02953.1 protein networkhttps://string-db.org/network/760011.Spico_1755Radical SAM domain protein; COGs: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); InterPro IPR007197; KEGG: str:Sterm_2101 radical SAM domain protein; PFAM: Radical SAM; SPTR: Putative unc [...]
AEC02954.1 protein networkhttps://string-db.org/network/760011.Spico_1756InterPro IPR002781; KEGG: ssm:Spirs_3034 protein of unknown function DUF81; PFAM: Protein of unknown function DUF81; SPTR: Putative uncharacterized protein; IMG reference gene:2503958072; PFAM: S [...]
AEC02955.1 protein networkhttps://string-db.org/network/760011.Spico_1757Hypothetical protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; KEGG: tte:TTE1809 alpha/beta fold family hydrolase; SPTR: Peptidoglycan-binding lysin domain protein; IMG re [...]
AEC02956.1 protein networkhttps://string-db.org/network/760011.Spico_1758COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: geo:Geob_2530 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthas [...]
AEC02957.1 protein networkhttps://string-db.org/network/760011.Spico_1759Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: dac:Daci_3532 AraC family transcriptional regulator; PFA [...]
AEC02958.1 protein networkhttps://string-db.org/network/760011.Spico_1760SUF system FeS assembly protein, NifU family; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR011341:IPR002871; KEGG: cbe:Cbei_1852 NifU family SUF system FeS assembly [...]
AEC02959.1 protein networkhttps://string-db.org/network/760011.Spico_1761Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
AEC02960.1 protein networkhttps://string-db.org/network/760011.Spico_1762SufBD protein; COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR000825; KEGG: cac:CA_C3290 iron-regulated ABC-type transporter membrane co [...]
AEC02961.1 protein networkhttps://string-db.org/network/760011.Spico_1763Iron-regulated ABC transporter membrane component SufB; COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR010231:IPR000825; KEGG: cbe:Cbei_ [...]
AEC02962.1 protein networkhttps://string-db.org/network/760011.Spico_1764Iron-regulated ABC transporter ATPase subunit SufC; COGs: COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component; InterPro IPR010230:IPR003439:IPR003593; KEGG: vpr:V [...]
AEC02963.1 protein networkhttps://string-db.org/network/760011.Spico_1765Ribonucleotide reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleo [...]
AEC02964.1 protein networkhttps://string-db.org/network/760011.Spico_1766Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [...]
purH protein networkhttps://string-db.org/network/760011.Spico_1767IMP cyclohydrolase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); HAMAP: AICARFT/IMPCHase bienzyme; InterPro IPR002695:IPR011607:IPR013982; [...]
AEC02966.1 protein networkhttps://string-db.org/network/760011.Spico_1768COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006097:IPR006096; KEGG: ssm:Spirs_3994 glutamate dehydrogenase (NADP(+)); PFAM: Glutamate/phenylalanine/leucine/valine deh [...]
AEC02967.1 protein networkhttps://string-db.org/network/760011.Spico_1769COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR006426:IPR000583:IPR001962; KEGG: fba:FIC_01692 asparagine synthetase B; PFAM: Asparagine synthase; Glutamine amidotransfera [...]
AEC02968.1 protein networkhttps://string-db.org/network/760011.Spico_1770Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378:IPR000408; KEGG: aeh:Mlg_2687 regulator of chromos [...]
AEC02969.1 protein networkhttps://string-db.org/network/760011.Spico_1771COGs: COG4992 Ornithine/acetylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; InterPro IPR004636:IPR005814; KEGG: eel:EUBELI_00596 acetylornithine ami [...]
argB protein networkhttps://string-db.org/network/760011.Spico_1772N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
argJ protein networkhttps://string-db.org/network/760011.Spico_1773N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the ace [...]
argC protein networkhttps://string-db.org/network/760011.Spico_1774N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydroge [...]
AEC02973.1 protein networkhttps://string-db.org/network/760011.Spico_1775COGs: COG1929 Glycerate kinase; InterPro IPR004381; KEGG: cth:Cthe_1592 glycerate kinase; PFAM: Glycerate kinase; PRIAM: Glycerate kinase; SPTR: Putative uncharacterized protein; TIGRFAM: Glycera [...]
AEC02974.1 protein networkhttps://string-db.org/network/760011.Spico_1776COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR002218; KEGG: csh:Closa_4238 glucose-inhibited division protein A; PFAM: Glucose-inhibited division protein A-related; SPTR: Glucose-inhibi [...]
AEC02975.1 protein networkhttps://string-db.org/network/760011.Spico_1777KEGG: csh:Closa_4239 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503958093.
AEC02976.1 protein networkhttps://string-db.org/network/760011.Spico_1778Hydantoinase/oxoprolinase; COGs: COG0145 N-methylhydantoinase A/acetone carboxylase beta subunit; InterPro IPR008040:IPR002821; KEGG: csh:Closa_4240 hydantoinase/oxoprolinase; PFAM: Hydantoinase/ [...]
AEC02977.1 protein networkhttps://string-db.org/network/760011.Spico_1779TRAP C4-dicarboxylate transport system permease DctM subunit; InterPro IPR010656; KEGG: csh:Closa_4241 C4-dicarboxylate anaerobic carrier-like protein; PFAM: TRAP C4-dicarboxylate transport syste [...]
AEC02978.1 protein networkhttps://string-db.org/network/760011.Spico_1780KEGG: csh:Closa_4242 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503958096.
AEC02979.1 protein networkhttps://string-db.org/network/760011.Spico_1781KEGG: csh:Closa_4243 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503958097.
AEC02980.1 protein networkhttps://string-db.org/network/760011.Spico_1782L-glutamine synthetase; COGs: COG3968 Uncharacterized protein related to glutamine synthetase; InterPro IPR008146; KEGG: cth:Cthe_0196 glutamine synthetase, catalytic region; PFAM: Glutamine synt [...]
AEC02981.1 protein networkhttps://string-db.org/network/760011.Spico_1783ANTAR domain protein; InterPro IPR005561; KEGG: cth:Cthe_0203 response regulator receiver/ANTAR domain-containing protein; PFAM: ANTAR; SPTR: Putative uncharacterized protein; IMG reference gene: [...]
pyrG protein networkhttps://string-db.org/network/760011.Spico_1784CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the fo [...]
argR protein networkhttps://string-db.org/network/760011.Spico_1785Arginine repressor, ArgR; Regulates arginine biosynthesis genes.
pgi protein networkhttps://string-db.org/network/760011.Spico_1786COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: ssm:Spirs_3245 phosphoglucose isomerase (PGI); PFAM: Phosphoglucose isomerase (PGI); [...]
AEC02985.1 protein networkhttps://string-db.org/network/760011.Spico_1787SPTR: Putative uncharacterized protein; IMG reference gene:2503958103.
pfkA protein networkhttps://string-db.org/network/760011.Spico_17886-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase typ [...]
AEC02987.1 protein networkhttps://string-db.org/network/760011.Spico_1789Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: ssm:Spirs_1023 aminotransferase class I and II; PFAM: Aminotransferase, clas [...]
ligA protein networkhttps://string-db.org/network/760011.Spico_1790DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy sourc [...]
AEC02989.1 protein networkhttps://string-db.org/network/760011.Spico_1791KEGG: bcb:BCB4264_A2969 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503958107.
AEC02990.1 protein networkhttps://string-db.org/network/760011.Spico_1792Aldehyde oxidase and xanthine dehydrogenase molybdopterin binding protein; COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR008274; KEGG: ssm [...]
AEC02991.1 protein networkhttps://string-db.org/network/760011.Spico_1793Hypothetical protein; KEGG: gga:417314 dynein, axonemal, heavy chain 9; SPTR: GE19955; IMG reference gene:2503958109.
AEC02992.1 protein networkhttps://string-db.org/network/760011.Spico_1794Molybdopterin dehydrogenase FAD-binding protein; COGs: COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM/CutM homologs; InterPro IPR002346; KEGG: ssm:Spirs_1328 molybdopterin [...]
AEC02993.1 protein networkhttps://string-db.org/network/760011.Spico_1795COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004805:IPR004013:IPR011708:IPR004365:IPR 003141; KEGG: ssm:Spirs_1327 DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase [...]
AEC02994.1 protein networkhttps://string-db.org/network/760011.Spico_1796InterPro IPR003425; KEGG: ssm:Spirs_1326 protein of unknown function YGGT; PFAM: Uncharacterised protein family Ycf19; SPTR: Putative uncharacterized protein; IMG reference gene:2503958112; PFAM: [...]
recG protein networkhttps://string-db.org/network/760011.Spico_1797ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwindin [...]
AEC02996.1 protein networkhttps://string-db.org/network/760011.Spico_1798Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398; KEGG: ssm:Spirs_1324 methyltransferase; PFAM: RNA methyltransferase, RsmD; SPTR: Methyltransferase, putative; T [...]
AEC02997.1 protein networkhttps://string-db.org/network/760011.Spico_1799COGs: COG3884 Acyl-ACP thioesterase; InterPro IPR002864; KEGG: dvm:DvMF_1428 acyl-ACP thioesterase; PFAM: Acyl-ACP thioesterase; SPTR: Acyl-ACP thioesterase; IMG reference gene:2503958115; PFAM: [...]
AEC02998.1 protein networkhttps://string-db.org/network/760011.Spico_1800SlyX family protein; InterPro IPR007236; KEGG: abo:ABO_2672 hypothetical protein; PFAM: SlyX; SPTR: Putative uncharacterized protein; IMG reference gene:2503958116; PFAM: SlyX.
AEC02999.1 protein networkhttps://string-db.org/network/760011.Spico_1801Rubredoxin-type Fe(Cys)4 protein; COGs: COG1773 Rubredoxin; InterPro IPR004039; KEGG: sta:STHERM_c04700 rubredoxin; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubredoxin; IMG reference gene:25 [...]
AEC03000.1 protein networkhttps://string-db.org/network/760011.Spico_1802Hypothetical protein; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; KEGG: aeh:Mlg_2687 regulator of chromosome condensation, RCC1; SPTR: Putative uncharacteri [...]
AEC03001.1 protein networkhttps://string-db.org/network/760011.Spico_1803COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: csh:Closa_0385 nitroreductase; PFAM: Nitroreductase-like; SPTR: Oxygen-insensitive NADPH nitroreductase; IMG reference gene:2503958119; PFA [...]
AEC03002.1 protein networkhttps://string-db.org/network/760011.Spico_1804Peptidase U61 LD-carboxypeptidase A; COGs: COG1619 conserved hypothetical protein; InterPro IPR003507; KEGG: cbl:CLK_2168 LD-carboxypeptidase family protein; PFAM: Peptidase S66, LD-carboxypeptid [...]
AEC03003.1 protein networkhttps://string-db.org/network/760011.Spico_1805COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: mta:Mot [...]
AEC03004.1 protein networkhttps://string-db.org/network/760011.Spico_1806Glutamyl aminopeptidase; COGs: COG1363 Cellulase M and related protein; InterPro IPR008007; KEGG: amu:Amuc_1103 glutamyl aminopeptidase; PFAM: Peptidase M42; PRIAM: Glutamyl aminopeptidase; SPTR: [...]
AEC03005.1 protein networkhttps://string-db.org/network/760011.Spico_1807Microcystin LR degradation protein MlrC; COGs: COG5476 conserved hypothetical protein; InterPro IPR015995:IPR010799; KEGG: ssm:Spirs_1401 microcystin LR degradation protein MlrC; PFAM: Microcysti [...]
cutC protein networkhttps://string-db.org/network/760011.Spico_1808CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family.
AEC03007.1 protein networkhttps://string-db.org/network/760011.Spico_1809InterPro IPR002192; KEGG: ssm:Spirs_3995 response regulator receiver protein; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; SPTR: Phosphoenolpyruvate synthase/pyruvate phosphate dikina [...]
AEC03008.1 protein networkhttps://string-db.org/network/760011.Spico_1810Xylose isomerase domain-containing protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307:IPR011418; KEGG: ssm:Spirs_0709 xylose isomerase domain protein TIM ba [...]
AEC03009.1 protein networkhttps://string-db.org/network/760011.Spico_1811Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: ssm:Spirs_0708 oxidoreductase domain protein; PFAM: Oxidoreductase, N-terminal; [...]
AEC03010.1 protein networkhttps://string-db.org/network/760011.Spico_1812Monosaccharide ABC transporter membrane protein, CUT2 family; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: ssm:Spirs [...]
AEC03011.1 protein networkhttps://string-db.org/network/760011.Spico_1813Monosaccharide ABC transporter ATP-binding protein, CUT2 family; COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: ssm:Spirs_0706 ABC transporter [...]
AEC03012.1 protein networkhttps://string-db.org/network/760011.Spico_1814Periplasmic binding protein/LacI transcriptional regulator; COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: ssm:Spirs_0705 periplasmic binding protein/LacI transcriptio [...]
AEC03013.1 protein networkhttps://string-db.org/network/760011.Spico_1815Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: ssm:Spirs_0704 transcriptional regulator, LacI family; PFAM: Periplasmic bind [...]
AEC03014.1 protein networkhttps://string-db.org/network/760011.Spico_1816Ribosomal large subunit pseudouridine synthase D; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: ssm:Spirs_4002 pseudouridine synthase; PFAM: Pseudouridine syn [...]
AEC03015.1 protein networkhttps://string-db.org/network/760011.Spico_1817COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205; KEGG: ssm:Spirs_4003 DNA topoisomerase (ATP-hydrolyzing); PFAM: DNA topoisomerase, type I [...]
AEC03016.1 protein networkhttps://string-db.org/network/760011.Spico_1818DNA topoisomerase IV subunit B; COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterPro IPR003594:IPR013506:IPR001241; KEGG: ssm:Spirs_4004 DNA topoisomeras [...]
AEC03017.1 protein networkhttps://string-db.org/network/760011.Spico_1819COGs: COG0668 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: fbl:Fbal_2937 MscS mechanosensitive ion channel; PFAM: Mechanosensitive ion channel MscS; SPTR: Small-conductan [...]
htpG protein networkhttps://string-db.org/network/760011.Spico_1820Chaperone protein htpG; Molecular chaperone. Has ATPase activity.
AEC03019.1 protein networkhttps://string-db.org/network/760011.Spico_1821ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: tle:Tlet_1118 ROK family protein; PFAM: ROK; SPTR: ROK family protein; IMG reference gene:25039 [...]
AEC03020.1 protein networkhttps://string-db.org/network/760011.Spico_1822KEGG: sta:STHERM_c03850 GTP-binding protein; SPTR: GTP-binding protein; IMG reference gene:2503958138.
AEC03021.1 protein networkhttps://string-db.org/network/760011.Spico_1823Phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006268:IPR006218:IPR001086:IPR002912; KEGG: ssm:Spirs_0275 phos [...]
AEC03022.1 protein networkhttps://string-db.org/network/760011.Spico_1824DNA-(apurinic or apyrimidinic site) lyase; COGs: COG0177 EndoIII-related endonuclease; InterPro IPR003265:IPR003651; KEGG: dol:Dole_2166 DNA-(apurinic or apyrimidinic site) lyase; PFAM: HhH-GPD d [...]
AEC03023.1 protein networkhttps://string-db.org/network/760011.Spico_1825Hypothetical protein; InterPro IPR011493; KEGG: avn:Avin_37890 filamentous hemagglutinin domain-containing protein; SPTR: Filamentous hemagglutinin domain-containing protein; IMG reference gene:2 [...]
AEC03024.1 protein networkhttps://string-db.org/network/760011.Spico_1826KEGG: azl:AZL_026760 major facilitator transporter; SPTR: Major facilitator transporter; IMG reference gene:2503958142.
AEC03025.1 protein networkhttps://string-db.org/network/760011.Spico_1827COGs: COG3323 conserved hypothetical protein; KEGG: pag:PLES_12181 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503958143.
pth protein networkhttps://string-db.org/network/760011.Spico_1828Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
AEC03027.1 protein networkhttps://string-db.org/network/760011.Spico_1829Alpha amylase catalytic region; COGs: COG0366 Glycosidase; InterPro IPR006047:IPR006589; KEGG: ssm:Spirs_0266 alpha amylase catalytic region; PFAM: Glycosyl hydrolase, family 13, catalytic domain [...]
AEC03028.1 protein networkhttps://string-db.org/network/760011.Spico_1830Hypothetical protein; COGs: COG1301 Na+/H+-dicarboxylate symporter; KEGG: ssm:Spirs_0263 transporter, putative; SPTR: Transporter, putative; IMG reference gene:2503958146; PFAM: Sodium:dicarboxyl [...]
AEC03029.1 protein networkhttps://string-db.org/network/760011.Spico_1831Hypothetical protein; KEGG: rci:RRC456 putative Na(+)/H(+) antiporter; SPTR: Putative uncharacterized protein; IMG reference gene:2503958147.
AEC03030.1 protein networkhttps://string-db.org/network/760011.Spico_1832Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR000408; KEGG: aeh:Mlg_2687 regulator of chromosome conden [...]
AEC03031.1 protein networkhttps://string-db.org/network/760011.Spico_1833Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: ssm:Spirs_0211 peptidase M24; PFAM: Peptidase M24, structural domain; Creatinase; SPTR: Peptidase, M24 fam [...]
lgt protein networkhttps://string-db.org/network/760011.Spico_1834Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
AEC03033.1 protein networkhttps://string-db.org/network/760011.Spico_1835COGs: COG0793 Periplasmic protease; InterPro IPR004447:IPR001478:IPR005151; KEGG: ssm:Spirs_0153 carboxyl-terminal protease; PFAM: Peptidase S41; PDZ/DHR/GLGF; SMART: Peptidase S41; PDZ/DHR/GLGF; [...]
AEC03034.1 protein networkhttps://string-db.org/network/760011.Spico_1836Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subuni [...]
AEC03035.1 protein networkhttps://string-db.org/network/760011.Spico_1837Transposase, IS605 OrfB family; COGs: COG0675 Transposase and inactivated derivatives; InterPro IPR010095:IPR001959; KEGG: xfm:Xfasm12_1563 transposase OrfB; PFAM: Transposase, probable, IS891/IS [...]
AEC03036.1 protein networkhttps://string-db.org/network/760011.Spico_1838Resolvase domain protein; COGs: COG2452 site-specific integrase-resolvase; InterPro IPR000551:IPR006119; KEGG: xfm:Xfasm12_1564 hypothetical protein; PFAM: Resolvase, N-terminal; HTH transcriptio [...]
AEC03037.1 protein networkhttps://string-db.org/network/760011.Spico_1839KEGG: har:HEAR2257 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503958161.
dnaX protein networkhttps://string-db.org/network/760011.Spico_1840DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' [...]
recR protein networkhttps://string-db.org/network/760011.Spico_1841DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
AEC03040.1 protein networkhttps://string-db.org/network/760011.Spico_1842KEGG: coc:Coch_0352 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503958164.
AEC03041.1 protein networkhttps://string-db.org/network/760011.Spico_1843Hypothetical protein; KEGG: pfh:PFHG_02927 conserved hypothetical protein; SPTR: Conserved Plasmodium protein; IMG reference gene:2503958165.
kduI protein networkhttps://string-db.org/network/760011.Spico_18444-deoxy-L-threo-5-hexulose uronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
AEC03043.1 protein networkhttps://string-db.org/network/760011.Spico_1845Gluconate 5-dehydrogenase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: snt:SPT_0369 gluconate 5-dehydrogenas [...]
AEC03044.1 protein networkhttps://string-db.org/network/760011.Spico_1846Heat shock protein DnaJ domain protein; COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623; KEGG: dat:HRM2_24840 DjlA; PFAM: Heat shock protein DnaJ [...]
AEC03045.1 protein networkhttps://string-db.org/network/760011.Spico_1847Hypothetical protein; COGs: COG1626 Neutral trehalase; KEGG: ssm:Spirs_0085 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503958169; PFAM: Trehalase.
AEC03046.1 protein networkhttps://string-db.org/network/760011.Spico_1848Conserved hypothetical protein CHP00147; COGs: COG1597 Sphingosine kinase; InterPro IPR001206:IPR005218; KEGG: ssm:Spirs_3801 diacylglycerol kinase catalytic region; PFAM: Diacylglycerol kinase, [...]
AEC03047.1 protein networkhttps://string-db.org/network/760011.Spico_1849MATE efflux family protein; COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: ssm:Spirs_0042 MATE efflux family protein; PFAM: Multi antimicrobial extrusion protein; SPTR: [...]
AEC03048.1 protein networkhttps://string-db.org/network/760011.Spico_1850COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR006680:IPR003764; KEGG: ssm:Spirs_1362 N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase 1; PRIAM: N-acetylg [...]
AEC03049.1 protein networkhttps://string-db.org/network/760011.Spico_1851Aminoacyl-histidine dipeptidase; COGs: COG2195 Di- and tripeptidase; InterPro IPR002933:IPR011650:IPR001160; KEGG: ssm:Spirs_0034 aminoacyl-histidine dipeptidase; PFAM: Peptidase M20, dimerisatio [...]
AEC03050.1 protein networkhttps://string-db.org/network/760011.Spico_1852Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR000408; KEGG: aeh:Mlg_2687 regulator of chromosome conden [...]
AEC03051.1 protein networkhttps://string-db.org/network/760011.Spico_1853COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: ssm:Spirs_0330 phospholipid/glycerol acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; SMART: P [...]
AEC03052.1 protein networkhttps://string-db.org/network/760011.Spico_1854Na+/glutamate symporter-like protein; COGs: COG0786 Na+/glutamate symporter; KEGG: ssm:Spirs_2474 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein; IMG reference g [...]
AEC03053.1 protein networkhttps://string-db.org/network/760011.Spico_1855Regulator of chromosome condensation RCC1; COGs: COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing protein; InterPro IPR013378:IPR011110:IPR000408; KEGG: aeh:Mlg_2687 regulator [...]
AEC03054.1 protein networkhttps://string-db.org/network/760011.Spico_1856Beta-lactamase domain protein; COGs: COG0426 flavoprotein; InterPro IPR001279:IPR008254; KEGG: ssm:Spirs_0020 uncharacterized flavoprotein; PFAM: Beta-lactamase-like; Flavodoxin/nitric oxide synt [...]
AEC03055.1 protein networkhttps://string-db.org/network/760011.Spico_1857Protein of unknown function DUF45; COGs: COG1451 metal-dependent hydrolase; InterPro IPR002725; KEGG: abo:ABO_2745 hypothetical protein; PFAM: Protein of unknown function DUF45; SPTR: Putative un [...]
AEC03056.1 protein networkhttps://string-db.org/network/760011.Spico_1858COGs: COG2431 membrane protein; InterPro IPR005642; KEGG: ssm:Spirs_0011 protein of unknown function DUF340 membrane; PFAM: Protein of unknown function DUF340, prokaryotic membrane; SPTR: Putativ [...]
AEC03057.1 protein networkhttps://string-db.org/network/760011.Spico_1859TraB family protein; COGs: COG1916 Uncharacterized homolog of PrgY (pheromone shutdown protein); InterPro IPR002816:IPR005230; KEGG: ssm:Spirs_4297 TraB family protein; PFAM: Pheromone shutdown-r [...]
radA protein networkhttps://string-db.org/network/760011.Spico_1860DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand [...]
AEC03059.1 protein networkhttps://string-db.org/network/760011.Spico_1861Peptidylprolyl isomerase; COGs: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130:IPR001179; KEGG: dps:DP1645 peptidyl-prolyl cis-trans isomerase; PF [...]
AEC03060.1 protein networkhttps://string-db.org/network/760011.Spico_1862parB-like partition protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: ssm:Spirs_4300 ParB-like partition protein; PFAM: ParB-like nuclease; SMART: ParB [...]
AEC03061.1 protein networkhttps://string-db.org/network/760011.Spico_1863COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: ssm:Spirs_4301 cobyrinic acid ac-diamide synthase; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Putative un [...]
AEC03062.1 protein networkhttps://string-db.org/network/760011.Spico_1864Nitrogen-fixing NifU domain-containing protein; COGs: COG0694 Thioredoxin-like protein and domains; InterPro IPR001075; KEGG: ssm:Spirs_4302 nitrogen-fixing NifU domain protein; PFAM: NIF system [...]
gyrA protein networkhttps://string-db.org/network/760011.Spico_1865DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
gyrB protein networkhttps://string-db.org/network/760011.Spico_1866DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
AEC01783.1 protein networkhttps://string-db.org/network/760011.Spico_R0016TfoX domain-containing protein; COGs: COG3070 Regulator of competence-specific genes; InterPro IPR007076; KEGG: pru:PRU_2356 TfoX N-terminal domain-containing protein; PFAM: TfoX, N-terminal; SPT [...]