Organism Overview: Blochmannia vafer


 
mnmG protein networkhttps://string-db.org/network/859654.BVAF_001tRNA uridine 5-carboxymethylaminomethyl modification enzyme; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, [...]
atpB protein networkhttps://string-db.org/network/859654.BVAF_002ATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
atpE protein networkhttps://string-db.org/network/859654.BVAF_003ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramemb [...]
atpF protein networkhttps://string-db.org/network/859654.BVAF_004ATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
atpH protein networkhttps://string-db.org/network/859654.BVAF_005ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extra [...]
atpA protein networkhttps://string-db.org/network/859654.BVAF_006ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family [...]
atpG protein networkhttps://string-db.org/network/859654.BVAF_007ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of [...]
atpD protein networkhttps://string-db.org/network/859654.BVAF_008ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alp [...]
atpC protein networkhttps://string-db.org/network/859654.BVAF_009ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.
glmU protein networkhttps://string-db.org/network/859654.BVAF_010Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catal [...]
mnmE protein networkhttps://string-db.org/network/859654.BVAF_011tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, [...]
yidCD protein networkhttps://string-db.org/network/859654.BVAF_012Inner membrane protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
rnpA protein networkhttps://string-db.org/network/859654.BVAF_013Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. [...]
rpmH protein networkhttps://string-db.org/network/859654.BVAF_01450S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
dnaN protein networkhttps://string-db.org/network/859654.BVAF_015DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadin [...]
gyrB protein networkhttps://string-db.org/network/859654.BVAF_016DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
ibpA protein networkhttps://string-db.org/network/859654.BVAF_017Small heat shock protein ibpA; Belongs to the small heat shock protein (HSP20) family.
BVAF_018 protein networkhttps://string-db.org/network/859654.BVAF_018Putative transmembrane protein.
glyQ protein networkhttps://string-db.org/network/859654.BVAF_019glycyl-tRNA synthetase alpha subunit.
glyS protein networkhttps://string-db.org/network/859654.BVAF_020glycyl-tRNA synthetase beta subunit.
sodA protein networkhttps://string-db.org/network/859654.BVAF_021Manganese superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family [...]
prlC protein networkhttps://string-db.org/network/859654.BVAF_022Oligopeptidase A.
pit protein networkhttps://string-db.org/network/859654.BVAF_023Putative low-affinity inorganic phosphate transporter.
ubiA protein networkhttps://string-db.org/network/859654.BVAF_0244-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubi [...]
zur protein networkhttps://string-db.org/network/859654.BVAF_025Zinc uptake regulation protein; Belongs to the Fur family.
dnaB protein networkhttps://string-db.org/network/859654.BVAF_026Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DN [...]
ssb protein networkhttps://string-db.org/network/859654.BVAF_027Single-stranded DNA binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of act [...]
yjcE protein networkhttps://string-db.org/network/859654.BVAF_028Sodium hydrogen antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [...]
gltP protein networkhttps://string-db.org/network/859654.BVAF_029Proton glutamate symport protein; Catalyzes the proton-dependent transport of glutamate and aspartate; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP su [...]
yjgF protein networkhttps://string-db.org/network/859654.BVAF_030Putative endoribonuclease L-PSP.
argI protein networkhttps://string-db.org/network/859654.BVAF_031Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs t [...]
valS protein networkhttps://string-db.org/network/859654.BVAF_032valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
holC protein networkhttps://string-db.org/network/859654.BVAF_033DNA polymerase III chi subunit.
pepA protein networkhttps://string-db.org/network/859654.BVAF_034Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
yjgP protein networkhttps://string-db.org/network/859654.BVAF_035Putative permease.
yjgQ protein networkhttps://string-db.org/network/859654.BVAF_036Putative permease.
yidZ protein networkhttps://string-db.org/network/859654.BVAF_037LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
BVAF_039 protein networkhttps://string-db.org/network/859654.BVAF_039Hypothetical protein.
BVAF_040 protein networkhttps://string-db.org/network/859654.BVAF_040ABC transporter (putative manganese transport system).
BVAF_041 protein networkhttps://string-db.org/network/859654.BVAF_041ABC transporter membrane protein (putative manganese transport system).
yhbG protein networkhttps://string-db.org/network/859654.BVAF_042ABC transporter.
lptA protein networkhttps://string-db.org/network/859654.BVAF_043Lipopolysaccharide transport periplasmic protein.
lptC protein networkhttps://string-db.org/network/859654.BVAF_044Conserved hypothetical protein; Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Belongs to the LptC family.
yrbA protein networkhttps://string-db.org/network/859654.BVAF_045bolA-like protein; Belongs to the BolA/IbaG family.
murA protein networkhttps://string-db.org/network/859654.BVAF_046UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
degQ protein networkhttps://string-db.org/network/859654.BVAF_047Protease; Belongs to the peptidase S1C family.
yhcB protein networkhttps://string-db.org/network/859654.BVAF_048Conserved hypothetical protein.
rplM protein networkhttps://string-db.org/network/859654.BVAF_04950S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages [...]
rpsI protein networkhttps://string-db.org/network/859654.BVAF_05030S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
yraP protein networkhttps://string-db.org/network/859654.BVAF_051Putative phospholipid-binding domain protein.
yraL protein networkhttps://string-db.org/network/859654.BVAF_052Tetrapyrrole methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
rpoD protein networkhttps://string-db.org/network/859654.BVAF_056RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primar [...]
dnaG protein networkhttps://string-db.org/network/859654.BVAF_057DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
rpsU protein networkhttps://string-db.org/network/859654.BVAF_05830S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
gcp protein networkhttps://string-db.org/network/859654.BVAF_059O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in t [...]
ygiH protein networkhttps://string-db.org/network/859654.BVAF_060Putative membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-ph [...]
folB protein networkhttps://string-db.org/network/859654.BVAF_061Dihydroneopterin aldolase.
cca protein networkhttps://string-db.org/network/859654.BVAF_062Multifunctional CCA protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order [...]
hldE protein networkhttps://string-db.org/network/859654.BVAF_063Bifunctional protein hldE; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to t [...]
yqiC protein networkhttps://string-db.org/network/859654.BVAF_064Conserved hypothetical protein.
ribB protein networkhttps://string-db.org/network/859654.BVAF_0653,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
plsC protein networkhttps://string-db.org/network/859654.BVAF_0661-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
metC protein networkhttps://string-db.org/network/859654.BVAF_067Cystathionine beta-lyase.
cutA protein networkhttps://string-db.org/network/859654.BVAF_069Divalent cation tolerance protein.
groES protein networkhttps://string-db.org/network/859654.BVAF_07010 kDa chaperonin groES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
groEL protein networkhttps://string-db.org/network/859654.BVAF_07160 kDa chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
efp protein networkhttps://string-db.org/network/859654.BVAF_072Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by [...]
yjeP protein networkhttps://string-db.org/network/859654.BVAF_073Putative membrane protein/mechanosensitive ion channel.
psd protein networkhttps://string-db.org/network/859654.BVAF_074Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
orn protein networkhttps://string-db.org/network/859654.BVAF_075Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.
yjeE protein networkhttps://string-db.org/network/859654.BVAF_077Putative nucleotide-binding protein.
amiB protein networkhttps://string-db.org/network/859654.BVAF_078N-acetylmuramoyl-L-alanine amidase.
miaA protein networkhttps://string-db.org/network/859654.BVAF_079tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(di [...]
hflX protein networkhttps://string-db.org/network/859654.BVAF_080GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase su [...]
hflK protein networkhttps://string-db.org/network/859654.BVAF_081HflK protein; HflC and HflK could encode or regulate a protease.
hflC protein networkhttps://string-db.org/network/859654.BVAF_082HflC protein; HflC and HflK could regulate a protease.
purA protein networkhttps://string-db.org/network/859654.BVAF_083Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to t [...]
rlmB protein networkhttps://string-db.org/network/859654.BVAF_08423S rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH fa [...]
rpsF protein networkhttps://string-db.org/network/859654.BVAF_08530S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
rpsR protein networkhttps://string-db.org/network/859654.BVAF_08630S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosom [...]
rplI protein networkhttps://string-db.org/network/859654.BVAF_08750S ribosomal protein L9; Binds to the 23S rRNA.
cysQ protein networkhttps://string-db.org/network/859654.BVAF_0883'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.
ytfM protein networkhttps://string-db.org/network/859654.BVAF_089Surface antigen protein.
ytfN protein networkhttps://string-db.org/network/859654.BVAF_090Conserved hypothetical protein.
ppa protein networkhttps://string-db.org/network/859654.BVAF_091Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
ispB protein networkhttps://string-db.org/network/859654.BVAF_092Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
rplU protein networkhttps://string-db.org/network/859654.BVAF_09350S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
rpmA protein networkhttps://string-db.org/network/859654.BVAF_09450S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
obgE protein networkhttps://string-db.org/network/859654.BVAF_095GTPase obgE/cgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in [...]
greA protein networkhttps://string-db.org/network/859654.BVAF_096Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trappi [...]
rlmE protein networkhttps://string-db.org/network/859654.BVAF_097Ribosomal RNA large subunit methyltransferase, ftsJ-like protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ri [...]
ftsH protein networkhttps://string-db.org/network/859654.BVAF_098Cell division protease ftsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane protein [...]
folP protein networkhttps://string-db.org/network/859654.BVAF_099Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate [...]
glmM protein networkhttps://string-db.org/network/859654.BVAF_100Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
secG protein networkhttps://string-db.org/network/859654.BVAF_101Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
nusA protein networkhttps://string-db.org/network/859654.BVAF_104Transcription elongation protein nusA; Participates in both transcription termination and antitermination.
infB protein networkhttps://string-db.org/network/859654.BVAF_105Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to [...]
rbfA protein networkhttps://string-db.org/network/859654.BVAF_106Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
truB protein networkhttps://string-db.org/network/859654.BVAF_107tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
rpsO protein networkhttps://string-db.org/network/859654.BVAF_10830S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
pnp protein networkhttps://string-db.org/network/859654.BVAF_109Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
deaD protein networkhttps://string-db.org/network/859654.BVAF_110Cold-shock DEAD box protein A; Belongs to the DEAD box helicase family.
holD protein networkhttps://string-db.org/network/859654.BVAF_111DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonu [...]
thrA protein networkhttps://string-db.org/network/859654.BVAF_112Bifunctional aspartokinase/homoserine dehydrogenase 1; In the C-terminal section; belongs to the homoserine dehydrogenase family.
thrB protein networkhttps://string-db.org/network/859654.BVAF_113Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
thrC protein networkhttps://string-db.org/network/859654.BVAF_114Threonine synthase.
dnaK protein networkhttps://string-db.org/network/859654.BVAF_115Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
dnaJ protein networkhttps://string-db.org/network/859654.BVAF_116Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an [...]
rpsT protein networkhttps://string-db.org/network/859654.BVAF_11730S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
ribF protein networkhttps://string-db.org/network/859654.BVAF_118Riboflavin biosynthesis protein RibF; Belongs to the ribF family.
ileS protein networkhttps://string-db.org/network/859654.BVAF_119isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
lspA protein networkhttps://string-db.org/network/859654.BVAF_120Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
ispH protein networkhttps://string-db.org/network/859654.BVAF_1214-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethyl [...]
dapB protein networkhttps://string-db.org/network/859654.BVAF_122Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
carA protein networkhttps://string-db.org/network/859654.BVAF_123Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.
carB protein networkhttps://string-db.org/network/859654.BVAF_124Carbamoyl-phosphate synthase large chain.
folA protein networkhttps://string-db.org/network/859654.BVAF_125Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
apaH protein networkhttps://string-db.org/network/859654.BVAF_126Bis(5'-nucleosyl)-tetraphosphatase.
ksgA protein networkhttps://string-db.org/network/859654.BVAF_127Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a c [...]
pdxA protein networkhttps://string-db.org/network/859654.BVAF_1284-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decar [...]
surA protein networkhttps://string-db.org/network/859654.BVAF_129Chaperone surA.
lptD protein networkhttps://string-db.org/network/859654.BVAF_130LPS-assembly protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
leuD protein networkhttps://string-db.org/network/859654.BVAF_1313-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. Leu [...]
leuC protein networkhttps://string-db.org/network/859654.BVAF_1323-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
leuB protein networkhttps://string-db.org/network/859654.BVAF_1333-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-met [...]
leuA protein networkhttps://string-db.org/network/859654.BVAF_1342-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isoprop [...]
mraW protein networkhttps://string-db.org/network/859654.BVAF_135S-adenosyl-L-methionine-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
ftsL protein networkhttps://string-db.org/network/859654.BVAF_136Putative cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division prot [...]
ftsI protein networkhttps://string-db.org/network/859654.BVAF_137Peptidoglycan synthase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
murE protein networkhttps://string-db.org/network/859654.BVAF_138UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (U [...]
murF protein networkhttps://string-db.org/network/859654.BVAF_139UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of mure [...]
mraY protein networkhttps://string-db.org/network/859654.BVAF_140phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY s [...]
murD protein networkhttps://string-db.org/network/859654.BVAF_141UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF [...]
ftsW protein networkhttps://string-db.org/network/859654.BVAF_142Cell division protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
murG protein networkhttps://string-db.org/network/859654.BVAF_143Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid interme [...]
murC protein networkhttps://string-db.org/network/859654.BVAF_144UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
ftsQ protein networkhttps://string-db.org/network/859654.BVAF_145Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, whi [...]
ftsA protein networkhttps://string-db.org/network/859654.BVAF_146Cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
ftsZ protein networkhttps://string-db.org/network/859654.BVAF_147Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing a [...]
lpxC protein networkhttps://string-db.org/network/859654.BVAF_148UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed st [...]
secA protein networkhttps://string-db.org/network/859654.BVAF_149Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the [...]
dksA protein networkhttps://string-db.org/network/859654.BVAF_150DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several am [...]
folK protein networkhttps://string-db.org/network/859654.BVAF_1512-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.
lpdA protein networkhttps://string-db.org/network/859654.BVAF_152Dihydrolipoyl dehydrogenase.
aceF protein networkhttps://string-db.org/network/859654.BVAF_153Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
aceE protein networkhttps://string-db.org/network/859654.BVAF_154Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
mrcB protein networkhttps://string-db.org/network/859654.BVAF_155Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domai [...]
erpA protein networkhttps://string-db.org/network/859654.BVAF_156Iron sulfur cluster insertion protein; Required for insertion of 4Fe-4S clusters for at least IspG.
pyrG protein networkhttps://string-db.org/network/859654.BVAF_157CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the fo [...]
eno protein networkhttps://string-db.org/network/859654.BVAF_158Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
cysJ protein networkhttps://string-db.org/network/859654.BVAF_159Sulfite reductase [NADPH] flavoprotein, alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activitie [...]
cysI protein networkhttps://string-db.org/network/859654.BVAF_160Sulfite reductase (NADPH) hemoprotein, beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities [...]
cysH protein networkhttps://string-db.org/network/859654.BVAF_161Phosphoadenosine phosphosulfate reductase; Belongs to the PAPS reductase family. CysH subfamily.
cysG protein networkhttps://string-db.org/network/859654.BVAF_162Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the [...]
cysD protein networkhttps://string-db.org/network/859654.BVAF_163Sulfate adenylyltransferase subunit 2.
cysN protein networkhttps://string-db.org/network/859654.BVAF_164Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase [...]
cysC protein networkhttps://string-db.org/network/859654.BVAF_165Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
ftsB protein networkhttps://string-db.org/network/859654.BVAF_166Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, whi [...]
ispD protein networkhttps://string-db.org/network/859654.BVAF_1672-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to [...]
ispF protein networkhttps://string-db.org/network/859654.BVAF_1682-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid [...]
nlpD protein networkhttps://string-db.org/network/859654.BVAF_169Lipoprotein.
alaS protein networkhttps://string-db.org/network/859654.BVAF_170alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
csrA protein networkhttps://string-db.org/network/859654.BVAF_171Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid g [...]
rpsP protein networkhttps://string-db.org/network/859654.BVAF_17430S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
rimM protein networkhttps://string-db.org/network/859654.BVAF_175Ribosome maturation factor rimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. [...]
trmD protein networkhttps://string-db.org/network/859654.BVAF_176tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rplS protein networkhttps://string-db.org/network/859654.BVAF_17750S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
aroF protein networkhttps://string-db.org/network/859654.BVAF_178Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptuloson [...]
tyrA protein networkhttps://string-db.org/network/859654.BVAF_179T-protein (includes chorismate mutase and prephenate dehydrogenase).
pheA protein networkhttps://string-db.org/network/859654.BVAF_180Prephenate dehydratase.
yfiO protein networkhttps://string-db.org/network/859654.BVAF_181Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the [...]
rluD protein networkhttps://string-db.org/network/859654.BVAF_182Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
clpB protein networkhttps://string-db.org/network/859654.BVAF_183Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to t [...]
murB protein networkhttps://string-db.org/network/859654.BVAF_184UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
birA protein networkhttps://string-db.org/network/859654.BVAF_185biotin-(acetyl-CoA-carboxylase) synthetase.
bfr protein networkhttps://string-db.org/network/859654.BVAF_190Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation wit [...]
rpsJ protein networkhttps://string-db.org/network/859654.BVAF_19130S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
rplC protein networkhttps://string-db.org/network/859654.BVAF_19250S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rplD protein networkhttps://string-db.org/network/859654.BVAF_19350S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
rplW protein networkhttps://string-db.org/network/859654.BVAF_19450S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main dock [...]
rplB protein networkhttps://string-db.org/network/859654.BVAF_19550S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It [...]
rpsS protein networkhttps://string-db.org/network/859654.BVAF_19630S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplV protein networkhttps://string-db.org/network/859654.BVAF_19750S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wal [...]
rpsC protein networkhttps://string-db.org/network/859654.BVAF_19830S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplP protein networkhttps://string-db.org/network/859654.BVAF_19950S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpmC protein networkhttps://string-db.org/network/859654.BVAF_20050S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
rpsQ protein networkhttps://string-db.org/network/859654.BVAF_20130S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rplN protein networkhttps://string-db.org/network/859654.BVAF_20250S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
rplX protein networkhttps://string-db.org/network/859654.BVAF_20350S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
rplE protein networkhttps://string-db.org/network/859654.BVAF_20450S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [...]
rpsN protein networkhttps://string-db.org/network/859654.BVAF_20530S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the un [...]
rpsH protein networkhttps://string-db.org/network/859654.BVAF_20630S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to [...]
rplF protein networkhttps://string-db.org/network/859654.BVAF_20750S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the t [...]
rplR protein networkhttps://string-db.org/network/859654.BVAF_20850S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protubera [...]
rpsE protein networkhttps://string-db.org/network/859654.BVAF_20930S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 fam [...]
rpmD protein networkhttps://string-db.org/network/859654.BVAF_21050S ribosomal protein L30.
rplO protein networkhttps://string-db.org/network/859654.BVAF_21150S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
secY protein networkhttps://string-db.org/network/859654.BVAF_212Preprotein translocase subunit secY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at t [...]
rpmJ protein networkhttps://string-db.org/network/859654.BVAF_21350S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.
rpsM protein networkhttps://string-db.org/network/859654.BVAF_21430S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 [...]
rpsK protein networkhttps://string-db.org/network/859654.BVAF_21530S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belon [...]
rpsD protein networkhttps://string-db.org/network/859654.BVAF_21630S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpoA protein networkhttps://string-db.org/network/859654.BVAF_217DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplQ protein networkhttps://string-db.org/network/859654.BVAF_21850S ribosomal protein L17.
fmt protein networkhttps://string-db.org/network/859654.BVAF_219methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethi [...]
def protein networkhttps://string-db.org/network/859654.BVAF_220Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a [...]
yrdC protein networkhttps://string-db.org/network/859654.BVAF_221Putative ribosome maturation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the [...]
aroE protein networkhttps://string-db.org/network/859654.BVAF_222Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshi [...]
gloB protein networkhttps://string-db.org/network/859654.BVAF_224Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
rnhA protein networkhttps://string-db.org/network/859654.BVAF_225Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
dnaQ protein networkhttps://string-db.org/network/859654.BVAF_226DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing func [...]
gmhA protein networkhttps://string-db.org/network/859654.BVAF_227Phosphoheptose isomerase.
ahpC protein networkhttps://string-db.org/network/859654.BVAF_229Peroxiredoxin, AhpC-TSA family.
tgt protein networkhttps://string-db.org/network/859654.BVAF_231Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in [...]
yajC protein networkhttps://string-db.org/network/859654.BVAF_232Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into mem [...]
secD protein networkhttps://string-db.org/network/859654.BVAF_233Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete pr [...]
secF protein networkhttps://string-db.org/network/859654.BVAF_234Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete pr [...]
ribD protein networkhttps://string-db.org/network/859654.BVAF_235Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-termi [...]
ribH protein networkhttps://string-db.org/network/859654.BVAF_2366,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. [...]
nusB protein networkhttps://string-db.org/network/859654.BVAF_237N utilization substance protein B-like protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator [...]
pgpA protein networkhttps://string-db.org/network/859654.BVAF_238Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
dxs protein networkhttps://string-db.org/network/859654.BVAF_2391-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (D [...]
thiI protein networkhttps://string-db.org/network/859654.BVAF_240tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the tran [...]
yajR protein networkhttps://string-db.org/network/859654.BVAF_241Membrane transport protein.
cyoE protein networkhttps://string-db.org/network/859654.BVAF_242Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
cyoD protein networkhttps://string-db.org/network/859654.BVAF_243Cytochrome o ubiquinol oxidase, subunit IV.
cyoC protein networkhttps://string-db.org/network/859654.BVAF_244Cytochrome o ubiquinol oxidase, subunit III.
cyoB protein networkhttps://string-db.org/network/859654.BVAF_245Cytochrome o ubiquinol oxidase, subunit I; Belongs to the heme-copper respiratory oxidase family.
cyoA protein networkhttps://string-db.org/network/859654.BVAF_246Ubiquinol oxidase, subunit II.
clpP protein networkhttps://string-db.org/network/859654.BVAF_247ATP-dependent Clp protease, proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degrad [...]
clpX protein networkhttps://string-db.org/network/859654.BVAF_248ATP-dependent Clp protease, ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the ab [...]
yggX protein networkhttps://string-db.org/network/859654.BVAF_249Putative Fe(2+)-trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthet [...]
mutY protein networkhttps://string-db.org/network/859654.BVAF_250A/G-specific adenine glycosylase.
yggS protein networkhttps://string-db.org/network/859654.BVAF_251Pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
yqgF protein networkhttps://string-db.org/network/859654.BVAF_252Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
yqgE protein networkhttps://string-db.org/network/859654.BVAF_253Conserved hypothetical protein; Belongs to the UPF0301 (AlgH) family.
metK protein networkhttps://string-db.org/network/859654.BVAF_254S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formati [...]
speB protein networkhttps://string-db.org/network/859654.BVAF_255Agmatinase; Belongs to the arginase family.
pgk protein networkhttps://string-db.org/network/859654.BVAF_256Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
fbaA protein networkhttps://string-db.org/network/859654.BVAF_257Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-b [...]
rpiA protein networkhttps://string-db.org/network/859654.BVAF_258Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
ygfA protein networkhttps://string-db.org/network/859654.BVAF_2595-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
zapA protein networkhttps://string-db.org/network/859654.BVAF_260Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation [...]
ubiH protein networkhttps://string-db.org/network/859654.BVAF_2612-octaprenyl-6-methoxyphenol hydroxylase.
visC protein networkhttps://string-db.org/network/859654.BVAF_262Putative monooxygenase.
ygfZ protein networkhttps://string-db.org/network/859654.BVAF_263tRNA-modifying protein ygfZ; Belongs to the GcvT family.
prfB protein networkhttps://string-db.org/network/859654.BVAF_264Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
lysS protein networkhttps://string-db.org/network/859654.BVAF_265lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
lysA protein networkhttps://string-db.org/network/859654.BVAF_266Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
rppH protein networkhttps://string-db.org/network/859654.BVAF_267RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can [...]
lgt protein networkhttps://string-db.org/network/859654.BVAF_268Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the [...]
recC protein networkhttps://string-db.org/network/859654.BVAF_269Exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dep [...]
recD protein networkhttps://string-db.org/network/859654.BVAF_270Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dep [...]
recB protein networkhttps://string-db.org/network/859654.BVAF_271Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-depe [...]
dapD protein networkhttps://string-db.org/network/859654.BVAF_2722,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.
map protein networkhttps://string-db.org/network/859654.BVAF_273Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and [...]
rpsB protein networkhttps://string-db.org/network/859654.BVAF_27430S ribosomal protein S20; Belongs to the universal ribosomal protein uS2 family.
tsf protein networkhttps://string-db.org/network/859654.BVAF_275Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis [...]
pyrH protein networkhttps://string-db.org/network/859654.BVAF_276Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
frr protein networkhttps://string-db.org/network/859654.BVAF_277Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosome [...]
dxr protein networkhttps://string-db.org/network/859654.BVAF_2781-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP).
uppS protein networkhttps://string-db.org/network/859654.BVAF_279Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E [...]
cdsA protein networkhttps://string-db.org/network/859654.BVAF_280Phosphatidate cytidylyltransferase.
rseP protein networkhttps://string-db.org/network/859654.BVAF_281RIP metalloprotease RseP.
yaeT protein networkhttps://string-db.org/network/859654.BVAF_282Outer membrane protein assembly factor YaeT; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Cons [...]
skp protein networkhttps://string-db.org/network/859654.BVAF_283Chaperone protein skp; Belongs to the skp family.
lpxD protein networkhttps://string-db.org/network/859654.BVAF_284UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved [...]
fabZ protein networkhttps://string-db.org/network/859654.BVAF_285(3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated [...]
lpxA protein networkhttps://string-db.org/network/859654.BVAF_286acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membr [...]
lpxB protein networkhttps://string-db.org/network/859654.BVAF_287lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid t [...]
rnhB protein networkhttps://string-db.org/network/859654.BVAF_288Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
dnaE protein networkhttps://string-db.org/network/859654.BVAF_289DNA polymerase III subunit alpha.
accA protein networkhttps://string-db.org/network/859654.BVAF_290acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its c [...]
tilS protein networkhttps://string-db.org/network/859654.BVAF_291tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is c [...]
proS protein networkhttps://string-db.org/network/859654.BVAF_292prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRN [...]
gmhB protein networkhttps://string-db.org/network/859654.BVAF_293D,D-heptose 1,7-bisphosphate phosphatase.
accC protein networkhttps://string-db.org/network/859654.BVAF_294Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarbox [...]
accB protein networkhttps://string-db.org/network/859654.BVAF_295Biotin carboxyl carrier protein of acetyl coA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the c [...]
aroQ protein networkhttps://string-db.org/network/859654.BVAF_2963-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
mreB protein networkhttps://string-db.org/network/859654.BVAF_297Rod shape-determining protein MreB.
mreC protein networkhttps://string-db.org/network/859654.BVAF_298Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
mreD protein networkhttps://string-db.org/network/859654.BVAF_299Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.
tldD protein networkhttps://string-db.org/network/859654.BVAF_300Putative modulator of DNA gyrase.
pmbA protein networkhttps://string-db.org/network/859654.BVAF_301Putative modulator of DNA gyrase.
lon protein networkhttps://string-db.org/network/859654.BVAF_302ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for [...]
apt protein networkhttps://string-db.org/network/859654.BVAF_303Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
dnaX protein networkhttps://string-db.org/network/859654.BVAF_304DNA polymerase III subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to [...]
adk protein networkhttps://string-db.org/network/859654.BVAF_305Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
lpxH protein networkhttps://string-db.org/network/859654.BVAF_306UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water [...]
cysS protein networkhttps://string-db.org/network/859654.BVAF_307cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
folD protein networkhttps://string-db.org/network/859654.BVAF_308Bifunctional protein folD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahy [...]
ytfF protein networkhttps://string-db.org/network/859654.BVAF_310Putative membrane protein.
mrdB protein networkhttps://string-db.org/network/859654.BVAF_311Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
mrdA protein networkhttps://string-db.org/network/859654.BVAF_312Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
ybeB protein networkhttps://string-db.org/network/859654.BVAF_313Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 3 [...]
holA protein networkhttps://string-db.org/network/859654.BVAF_314DNA polymerase III, delta subunit.
rlpB protein networkhttps://string-db.org/network/859654.BVAF_315Hypothetical protein.
leuS protein networkhttps://string-db.org/network/859654.BVAF_316leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
lnt protein networkhttps://string-db.org/network/859654.BVAF_317Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrol [...]
ybeX protein networkhttps://string-db.org/network/859654.BVAF_318Putative transport protein.
ybeY protein networkhttps://string-db.org/network/859654.BVAF_319Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
ybeZ protein networkhttps://string-db.org/network/859654.BVAF_320phoH-like protein.
ubiF protein networkhttps://string-db.org/network/859654.BVAF_3212-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
nagA protein networkhttps://string-db.org/network/859654.BVAF_325N-acetylglucosamine-6-phosphate deacetylase.
nagB protein networkhttps://string-db.org/network/859654.BVAF_326Glucosamine-6-phosphate deaminase.
glnS protein networkhttps://string-db.org/network/859654.BVAF_327glutaminyl-tRNA synthetase.
fldA protein networkhttps://string-db.org/network/859654.BVAF_328Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
sdhC protein networkhttps://string-db.org/network/859654.BVAF_329Succinate dehydrogenase, cytochrome b556 subunit.
sdhD protein networkhttps://string-db.org/network/859654.BVAF_330Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
sdhA protein networkhttps://string-db.org/network/859654.BVAF_331Succinate dehydrogenase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
sdhB protein networkhttps://string-db.org/network/859654.BVAF_332Succinate dehydrogenase iron-sulfur subunit.
sucA protein networkhttps://string-db.org/network/859654.BVAF_3332-oxoglutarate dehydrogenase E1 component.
sucB protein networkhttps://string-db.org/network/859654.BVAF_334Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step [...]
sucC protein networkhttps://string-db.org/network/859654.BVAF_335succinyl-CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represen [...]
sucD protein networkhttps://string-db.org/network/859654.BVAF_336succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP an [...]
tolQ protein networkhttps://string-db.org/network/859654.BVAF_337Protein TolQ.
tolR protein networkhttps://string-db.org/network/859654.BVAF_338Protein TolR.
tolA protein networkhttps://string-db.org/network/859654.BVAF_339tolA domain protein.
tolB protein networkhttps://string-db.org/network/859654.BVAF_340Protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key int [...]
pal protein networkhttps://string-db.org/network/859654.BVAF_341Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
ygbF protein networkhttps://string-db.org/network/859654.BVAF_342Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.
pgl protein networkhttps://string-db.org/network/859654.BVAF_3436-phosphogluconolactonase.
gpmA protein networkhttps://string-db.org/network/859654.BVAF_3442,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- depende [...]
ybhL protein networkhttps://string-db.org/network/859654.BVAF_345Putative membrane protein; Belongs to the BI1 family.
engD protein networkhttps://string-db.org/network/859654.BVAF_346GTP-dependent nucleic acid-binding protein engD.
pth protein networkhttps://string-db.org/network/859654.BVAF_347peptidyl-tRNA hydrolase.
prs protein networkhttps://string-db.org/network/859654.BVAF_348Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hy [...]
ispE protein networkhttps://string-db.org/network/859654.BVAF_3494-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. I [...]
lolB protein networkhttps://string-db.org/network/859654.BVAF_350Outer membrane lipoprotein LolB.
prfA protein networkhttps://string-db.org/network/859654.BVAF_351Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
hemK protein networkhttps://string-db.org/network/859654.BVAF_352Protein methyltransferase HemK; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to th [...]
kdsA protein networkhttps://string-db.org/network/859654.BVAF_3532-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family.
thrS protein networkhttps://string-db.org/network/859654.BVAF_354threonyl-tRNA synthetase.
infC protein networkhttps://string-db.org/network/859654.BVAF_355Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enha [...]
rpmI protein networkhttps://string-db.org/network/859654.BVAF_35650S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
rplT protein networkhttps://string-db.org/network/859654.BVAF_35750S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing func [...]
pheS protein networkhttps://string-db.org/network/859654.BVAF_358phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
pheT protein networkhttps://string-db.org/network/859654.BVAF_359phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
lplA protein networkhttps://string-db.org/network/859654.BVAF_360Lipoate-protein ligase A; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dep [...]
sufA protein networkhttps://string-db.org/network/859654.BVAF_361FeS cluster assembly protein sufA; Belongs to the HesB/IscA family.
sufB protein networkhttps://string-db.org/network/859654.BVAF_362FeS cluster assembly protein sufB.
sufC protein networkhttps://string-db.org/network/859654.BVAF_363FeS assembly ATPase SufC.
sufD protein networkhttps://string-db.org/network/859654.BVAF_364FeS cluster assembly protein sufD.
sufS protein networkhttps://string-db.org/network/859654.BVAF_365Cysteine desulfurase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomo [...]
sufE protein networkhttps://string-db.org/network/859654.BVAF_366Cysteine desulfuration protein sufE.
lpp protein networkhttps://string-db.org/network/859654.BVAF_367Major outer membrane lipoprotein.
ribE protein networkhttps://string-db.org/network/859654.BVAF_369Riboflavin synthase, alpha subunit.
grxD protein networkhttps://string-db.org/network/859654.BVAF_370Glutaredoxin-4; Belongs to the glutaredoxin family. Monothiol subfamily.
rnt protein networkhttps://string-db.org/network/859654.BVAF_371Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP [...]
slyA protein networkhttps://string-db.org/network/859654.BVAF_372Transcriptional regulator slyA.
pdxH protein networkhttps://string-db.org/network/859654.BVAF_373Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
tyrS protein networkhttps://string-db.org/network/859654.BVAF_374tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
nth protein networkhttps://string-db.org/network/859654.BVAF_375Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- [...]
fumC protein networkhttps://string-db.org/network/859654.BVAF_376Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamil [...]
BVAF_377 protein networkhttps://string-db.org/network/859654.BVAF_377Hypothetical protein.
ubiX protein networkhttps://string-db.org/network/859654.BVAF_3783-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylas [...]
kdsB protein networkhttps://string-db.org/network/859654.BVAF_3793-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
ycaR protein networkhttps://string-db.org/network/859654.BVAF_380Hypothetical protein.
lpxK protein networkhttps://string-db.org/network/859654.BVAF_381Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis [...]
msbA protein networkhttps://string-db.org/network/859654.BVAF_382Lipid A export ATP-binding/permease protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) [...]
rpsA protein networkhttps://string-db.org/network/859654.BVAF_38330S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
cmk protein networkhttps://string-db.org/network/859654.BVAF_384Cytidylate kinase.
aroA protein networkhttps://string-db.org/network/859654.BVAF_3853-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl [...]
serC protein networkhttps://string-db.org/network/859654.BVAF_386Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belon [...]
serS protein networkhttps://string-db.org/network/859654.BVAF_387seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further [...]
lolA protein networkhttps://string-db.org/network/859654.BVAF_388Outer membrane lipocarrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue af [...]
ftsK protein networkhttps://string-db.org/network/859654.BVAF_389DNA translocase ftsK; Belongs to the FtsK/SpoIIIE/SftA family.
trxB protein networkhttps://string-db.org/network/859654.BVAF_390Thioredoxin reductase.
infA protein networkhttps://string-db.org/network/859654.BVAF_391Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl- [...]
oprC protein networkhttps://string-db.org/network/859654.BVAF_392TonB-dependent copper receptor.
emtA protein networkhttps://string-db.org/network/859654.BVAF_394Endo-type membrane-bound lytic murein transglycosylase A.
mnmA protein networkhttps://string-db.org/network/859654.BVAF_395tRNA-specific 2-thiouridylase mnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step o [...]
purB protein networkhttps://string-db.org/network/859654.BVAF_396Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
lolE protein networkhttps://string-db.org/network/859654.BVAF_397Lipoprotein-releasing system transmembrane protein lolE.
lolD protein networkhttps://string-db.org/network/859654.BVAF_398Lipoprotein-releasing system ATP-binding protein lolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner memb [...]
lolC protein networkhttps://string-db.org/network/859654.BVAF_399Lipoprotein-releasing system transmembrane protein lolC.
ycfM protein networkhttps://string-db.org/network/859654.BVAF_400Conserved hypothetical protein.
hinT protein networkhttps://string-db.org/network/859654.BVAF_401HIT-like protein hinT.
ycfH protein networkhttps://string-db.org/network/859654.BVAF_402TatD family hydrolase.
holB protein networkhttps://string-db.org/network/859654.BVAF_403DNA polymerase III subunit delta.
tmk protein networkhttps://string-db.org/network/859654.BVAF_404Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
pabC protein networkhttps://string-db.org/network/859654.BVAF_405Aminodeoxychorismate lyase.
acpP protein networkhttps://string-db.org/network/859654.BVAF_406Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
fabG protein networkhttps://string-db.org/network/859654.BVAF_4073-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cy [...]
fabD protein networkhttps://string-db.org/network/859654.BVAF_408Malonyl CoA-acyl carrier protein transacylase.
fabH protein networkhttps://string-db.org/network/859654.BVAF_4093-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first [...]
plsX protein networkhttps://string-db.org/network/859654.BVAF_410Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but n [...]
rpmF protein networkhttps://string-db.org/network/859654.BVAF_41150S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
rne protein networkhttps://string-db.org/network/859654.BVAF_412Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation [...]
erfK protein networkhttps://string-db.org/network/859654.BVAF_413Protein erfK/srfK.
pgsA protein networkhttps://string-db.org/network/859654.BVAF_416CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
tusE protein networkhttps://string-db.org/network/859654.BVAF_419Sulfurtransferase tusE; Part of a sulfur-relay system.
hspQ protein networkhttps://string-db.org/network/859654.BVAF_420Heat shock protein hspQ; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family.
fabA protein networkhttps://string-db.org/network/859654.BVAF_4213-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-deceno [...]
asnS protein networkhttps://string-db.org/network/859654.BVAF_422asparaginyl-tRNA synthetase.
aspC protein networkhttps://string-db.org/network/859654.BVAF_423Aspartate aminotransferase.
ycbL protein networkhttps://string-db.org/network/859654.BVAF_424Metallo-beta-lactamase superfamily protein.
fabI protein networkhttps://string-db.org/network/859654.BVAF_425Enoyl-[acyl-carrier-protein] reductase.
ribA protein networkhttps://string-db.org/network/859654.BVAF_426GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
trpE protein networkhttps://string-db.org/network/859654.BVAF_427Anthranilate synthase component I.
trpG protein networkhttps://string-db.org/network/859654.BVAF_428Glutamine amidotransferase.
trpD protein networkhttps://string-db.org/network/859654.BVAF_429Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranila [...]
trpC protein networkhttps://string-db.org/network/859654.BVAF_430Tryptophan biosynthesis protein trpCF; Belongs to the TrpF family.
trpB protein networkhttps://string-db.org/network/859654.BVAF_431Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
trpA protein networkhttps://string-db.org/network/859654.BVAF_432Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
tonB protein networkhttps://string-db.org/network/859654.BVAF_433TonB-like protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act [...]
cls protein networkhttps://string-db.org/network/859654.BVAF_434Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
tdk protein networkhttps://string-db.org/network/859654.BVAF_435Thymidine kinase.
xthA protein networkhttps://string-db.org/network/859654.BVAF_436Exodeoxyribonuclease III.
sppA protein networkhttps://string-db.org/network/859654.BVAF_437Signal peptide peptidase SppA.
gap protein networkhttps://string-db.org/network/859654.BVAF_438Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
dsbB protein networkhttps://string-db.org/network/859654.BVAF_439Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
minC protein networkhttps://string-db.org/network/859654.BVAF_440Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments tha [...]
minD protein networkhttps://string-db.org/network/859654.BVAF_441Septum site-determining protein MinD.
minE protein networkhttps://string-db.org/network/859654.BVAF_442Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensu [...]
yeaZ protein networkhttps://string-db.org/network/859654.BVAF_443Glycoprotease.
pabB protein networkhttps://string-db.org/network/859654.BVAF_444Para-aminobenzoate synthase component 1.
yoaE protein networkhttps://string-db.org/network/859654.BVAF_445Membrane transport protein.
manX protein networkhttps://string-db.org/network/859654.BVAF_446PTS system mannose-specific EIIAB component.
manY protein networkhttps://string-db.org/network/859654.BVAF_447Mannose permease IIC component.
manZ protein networkhttps://string-db.org/network/859654.BVAF_448Mannose permease IID component.
cspC protein networkhttps://string-db.org/network/859654.BVAF_449Cold shock-like protein cspC.
zwf protein networkhttps://string-db.org/network/859654.BVAF_450Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
pykA protein networkhttps://string-db.org/network/859654.BVAF_451Pyruvate kinase II; Belongs to the pyruvate kinase family.
yebA protein networkhttps://string-db.org/network/859654.BVAF_452Peptidase.
aspS protein networkhttps://string-db.org/network/859654.BVAF_453aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor [...]
argS protein networkhttps://string-db.org/network/859654.BVAF_454arginyl-tRNA synthetase.
mviN protein networkhttps://string-db.org/network/859654.BVAF_455Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
mdtH protein networkhttps://string-db.org/network/859654.BVAF_456Multidrug resistance protein mdtH.
gutQ protein networkhttps://string-db.org/network/859654.BVAF_460Arabinose 5-phosphate isomerase.
yeeX protein networkhttps://string-db.org/network/859654.BVAF_461Conserved hypothetical protein; Belongs to the UPF0265 family.
sbcB protein networkhttps://string-db.org/network/859654.BVAF_462Exodeoxyribonuclease I.
hisG protein networkhttps://string-db.org/network/859654.BVAF_463ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate [...]
hisD protein networkhttps://string-db.org/network/859654.BVAF_464Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
hisC protein networkhttps://string-db.org/network/859654.BVAF_465Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
hisB protein networkhttps://string-db.org/network/859654.BVAF_466Histidine biosynthesis bifunctional protein hisB; In the N-terminal section; belongs to the histidinol- phosphatase family.
hisH protein networkhttps://string-db.org/network/859654.BVAF_467Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydroly [...]
hisA protein networkhttps://string-db.org/network/859654.BVAF_4681-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.
hisF protein networkhttps://string-db.org/network/859654.BVAF_469Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that prod [...]
hisI protein networkhttps://string-db.org/network/859654.BVAF_470Histidine biosynthesis bifunctional protein hisIE; In the N-terminal section; belongs to the PRA-CH family.
gnd protein networkhttps://string-db.org/network/859654.BVAF_4716-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
metG protein networkhttps://string-db.org/network/859654.BVAF_472methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
folE protein networkhttps://string-db.org/network/859654.BVAF_473GTP cyclohydrolase I.
rplY protein networkhttps://string-db.org/network/859654.BVAF_47450S ribosomal protein L25; Belongs to the bacterial ribosomal protein bL25 family.
ddl protein networkhttps://string-db.org/network/859654.BVAF_475D-alanine--D-alanine ligase family protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
omp protein networkhttps://string-db.org/network/859654.BVAF_476Outer membrane protein.
gyrA protein networkhttps://string-db.org/network/859654.BVAF_477DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in [...]
ubiG protein networkhttps://string-db.org/network/859654.BVAF_4783-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. Ub [...]
nrdA protein networkhttps://string-db.org/network/859654.BVAF_479Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [...]
nrdB protein networkhttps://string-db.org/network/859654.BVAF_480Ribonucleoside-diphosphate reductase 1 subunit beta.
yfaE protein networkhttps://string-db.org/network/859654.BVAF_4812Fe-2S iron-sulfur cluster binding domain protein.
nuoN protein networkhttps://string-db.org/network/859654.BVAF_482NADH-quinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoM protein networkhttps://string-db.org/network/859654.BVAF_483NADH-quinone oxidoreductase subunit M.
nuoL protein networkhttps://string-db.org/network/859654.BVAF_484NADH-quinone oxidoreductase subunit L.
nuoK protein networkhttps://string-db.org/network/859654.BVAF_485NADH-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoJ protein networkhttps://string-db.org/network/859654.BVAF_486NADH-quinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton trans [...]
nuoI protein networkhttps://string-db.org/network/859654.BVAF_487NADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoH protein networkhttps://string-db.org/network/859654.BVAF_488NADH-quinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
nuoG protein networkhttps://string-db.org/network/859654.BVAF_489NADH-quinone oxidoreductase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton trans [...]
nuoF protein networkhttps://string-db.org/network/859654.BVAF_490NADH-quinone oxidoreductase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit fa [...]
nuoE protein networkhttps://string-db.org/network/859654.BVAF_491NADH-quinone oxidoreductase subunit E.
nuoC protein networkhttps://string-db.org/network/859654.BVAF_492NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the [...]
nuoB protein networkhttps://string-db.org/network/859654.BVAF_493NADH-quinone oxidoreductase, subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the e [...]
nuoA protein networkhttps://string-db.org/network/859654.BVAF_494NADH-quinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the en [...]
folC protein networkhttps://string-db.org/network/859654.BVAF_495Bifunctional protein folC; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or [...]
accD protein networkhttps://string-db.org/network/859654.BVAF_496Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its [...]
truA protein networkhttps://string-db.org/network/859654.BVAF_497tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
pdxB protein networkhttps://string-db.org/network/859654.BVAF_498Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
fabB protein networkhttps://string-db.org/network/859654.BVAF_4993-oxoacyl-[acyl-carrier-protein] synthase 1; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
yfcB protein networkhttps://string-db.org/network/859654.BVAF_500Uncharacterized adenine-specific methylase; Belongs to the protein N5-glutamine methyltransferase family.
aroC protein networkhttps://string-db.org/network/859654.BVAF_501Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
mntH protein networkhttps://string-db.org/network/859654.BVAF_503Manganese transport protein mntH; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.
gltX protein networkhttps://string-db.org/network/859654.BVAF_504glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end [...]
ligA protein networkhttps://string-db.org/network/859654.BVAF_507DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy sourc [...]
cysK protein networkhttps://string-db.org/network/859654.BVAF_508Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
ptsH protein networkhttps://string-db.org/network/859654.BVAF_509Phosphocarrier protein HPr.
ptsI protein networkhttps://string-db.org/network/859654.BVAF_510Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate ac [...]
cysA protein networkhttps://string-db.org/network/859654.BVAF_511Sulfate/thiosulfate import ATP-binding protein cysA; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
cysW protein networkhttps://string-db.org/network/859654.BVAF_512Sulfate transport system permease protein cysW.
cysU protein networkhttps://string-db.org/network/859654.BVAF_513Sulfate transport system permease protein cysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport syste [...]
cysP protein networkhttps://string-db.org/network/859654.BVAF_514Thiosulfate-binding protein.
tal protein networkhttps://string-db.org/network/859654.BVAF_515Transaldolase.
tktA protein networkhttps://string-db.org/network/859654.BVAF_516Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
dapE protein networkhttps://string-db.org/network/859654.BVAF_517Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in [...]
dapA protein networkhttps://string-db.org/network/859654.BVAF_518Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
upp protein networkhttps://string-db.org/network/859654.BVAF_520Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
BVAF_521 protein networkhttps://string-db.org/network/859654.BVAF_521Hypothetical protein.
ureG protein networkhttps://string-db.org/network/859654.BVAF_522Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
ureF protein networkhttps://string-db.org/network/859654.BVAF_523Urease accessory protein ureF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
ureC protein networkhttps://string-db.org/network/859654.BVAF_524Urease, alpha subunit.
ureB protein networkhttps://string-db.org/network/859654.BVAF_525Urease subunit beta; Belongs to the urease beta subunit family.
ureA protein networkhttps://string-db.org/network/859654.BVAF_526Urease subunit gamma; Belongs to the urease gamma subunit family.
ureD protein networkhttps://string-db.org/network/859654.BVAF_527Urease accessory protein ureD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
guaA protein networkhttps://string-db.org/network/859654.BVAF_528GMP synthase; Catalyzes the synthesis of GMP from XMP.
guaB protein networkhttps://string-db.org/network/859654.BVAF_529Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesi [...]
mqo protein networkhttps://string-db.org/network/859654.BVAF_530Malate dehydrogenase.
engA protein networkhttps://string-db.org/network/859654.BVAF_531GTP-binding protein engA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) G [...]
hisS protein networkhttps://string-db.org/network/859654.BVAF_532histidyl-tRNA synthetase.
ispG protein networkhttps://string-db.org/network/859654.BVAF_5334-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG fa [...]
rlmN protein networkhttps://string-db.org/network/859654.BVAF_534Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial [...]
ndk protein networkhttps://string-db.org/network/859654.BVAF_535Nucleoside diphosphate kinase.
iscS protein networkhttps://string-db.org/network/859654.BVAF_536Cysteine desulfurase.
suhB protein networkhttps://string-db.org/network/859654.BVAF_537Inositol-1-monophosphatase.
glyA protein networkhttps://string-db.org/network/859654.BVAF_538Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major so [...]
tadA protein networkhttps://string-db.org/network/859654.BVAF_539tRNA-specific adenosine deaminase.
acpS protein networkhttps://string-db.org/network/859654.BVAF_540Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
pdxJ protein networkhttps://string-db.org/network/859654.BVAF_541Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amin [...]
rnc protein networkhttps://string-db.org/network/859654.BVAF_542Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some m [...]
lepB protein networkhttps://string-db.org/network/859654.BVAF_543Signal peptidase I; Belongs to the peptidase S26 family.
lepA protein networkhttps://string-db.org/network/859654.BVAF_544GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codo [...]
ung protein networkhttps://string-db.org/network/859654.BVAF_545uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
grpE protein networkhttps://string-db.org/network/859654.BVAF_546Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleot [...]
ppnK protein networkhttps://string-db.org/network/859654.BVAF_547Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically t [...]
smpA protein networkhttps://string-db.org/network/859654.BVAF_548Small protein A.
yfjG protein networkhttps://string-db.org/network/859654.BVAF_549Polyketide cyclase/dehydrase family protein.
smpB protein networkhttps://string-db.org/network/859654.BVAF_550ssrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tm [...]
qacE protein networkhttps://string-db.org/network/859654.BVAF_552Quaternary ammonium compound-resistance protein qacE.
pssA protein networkhttps://string-db.org/network/859654.BVAF_553CDP-diacylglycerol--serine O-phosphatidyltransferase.
purH protein networkhttps://string-db.org/network/859654.BVAF_557Bifunctional purine biosynthesis protein PurH.
rpoC protein networkhttps://string-db.org/network/859654.BVAF_558DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/859654.BVAF_559DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplL protein networkhttps://string-db.org/network/859654.BVAF_56050S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the ba [...]
rplJ protein networkhttps://string-db.org/network/859654.BVAF_56150S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal prot [...]
rplA protein networkhttps://string-db.org/network/859654.BVAF_56250S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplK protein networkhttps://string-db.org/network/859654.BVAF_56350S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
nusG protein networkhttps://string-db.org/network/859654.BVAF_564Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the [...]
secE protein networkhttps://string-db.org/network/859654.BVAF_565Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; B [...]
tuf protein networkhttps://string-db.org/network/859654.BVAF_566Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
fusA protein networkhttps://string-db.org/network/859654.BVAF_567Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) [...]
rpsG protein networkhttps://string-db.org/network/859654.BVAF_56830S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit inte [...]
rpsL protein networkhttps://string-db.org/network/859654.BVAF_56930S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S an [...]
pabA protein networkhttps://string-db.org/network/859654.BVAF_570Para-aminobenzoate synthase glutamine amidotransferase component II.
trpS protein networkhttps://string-db.org/network/859654.BVAF_571tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
rpe protein networkhttps://string-db.org/network/859654.BVAF_572Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
aroB protein networkhttps://string-db.org/network/859654.BVAF_5733-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
aroK protein networkhttps://string-db.org/network/859654.BVAF_574Shikimate kinase 1; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
nfuA protein networkhttps://string-db.org/network/859654.BVAF_575Fe/S biogenesis protein nfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S protei [...]
asd protein networkhttps://string-db.org/network/859654.BVAF_576Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family.
yhgN protein networkhttps://string-db.org/network/859654.BVAF_577Putative MarC family protein.
yigL protein networkhttps://string-db.org/network/859654.BVAF_578Cof-like hydrolase.
corA protein networkhttps://string-db.org/network/859654.BVAF_579Magnesium transport protein corA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
yigB protein networkhttps://string-db.org/network/859654.BVAF_580Putative HAD-superfamily hydrolase.
dapF protein networkhttps://string-db.org/network/859654.BVAF_581Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of t [...]
hemC protein networkhttps://string-db.org/network/859654.BVAF_582Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
hemD protein networkhttps://string-db.org/network/859654.BVAF_583uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
rho protein networkhttps://string-db.org/network/859654.BVAF_588Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and re [...]
trxA protein networkhttps://string-db.org/network/859654.BVAF_589Thioredoxin; Belongs to the thioredoxin family.
ilvC protein networkhttps://string-db.org/network/859654.BVAF_590Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yie [...]
ilvA protein networkhttps://string-db.org/network/859654.BVAF_591Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine [...]
ilvD protein networkhttps://string-db.org/network/859654.BVAF_592Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
ilvE protein networkhttps://string-db.org/network/859654.BVAF_593Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
ilvM protein networkhttps://string-db.org/network/859654.BVAF_594Putative acetolactate synthase isozyme 2 small subunit.
ilvG protein networkhttps://string-db.org/network/859654.BVAF_595Acetolactate synthase isozyme 2 large subunit.
murI protein networkhttps://string-db.org/network/859654.BVAF_599Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
metF protein networkhttps://string-db.org/network/859654.BVAF_6005,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
metB protein networkhttps://string-db.org/network/859654.BVAF_601Cystathionine gamma-synthase.
rpmE protein networkhttps://string-db.org/network/859654.BVAF_60250S ribosomal protein L31; Binds the 23S rRNA.
fpr protein networkhttps://string-db.org/network/859654.BVAF_603ferredoxin--NADP reductase.
tpiA protein networkhttps://string-db.org/network/859654.BVAF_604Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the [...]
pfkA protein networkhttps://string-db.org/network/859654.BVAF_6056-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
cysE protein networkhttps://string-db.org/network/859654.BVAF_606Serine acetyltransferase; Belongs to the transferase hexapeptide repeat family.
gpsA protein networkhttps://string-db.org/network/859654.BVAF_607Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
grxC protein networkhttps://string-db.org/network/859654.BVAF_608Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
yibN protein networkhttps://string-db.org/network/859654.BVAF_609Rhodanese-like domain protein.
hldD protein networkhttps://string-db.org/network/859654.BVAF_610ADP-L-glycero-D-manno-heptose-6-epimerase.
rfaC protein networkhttps://string-db.org/network/859654.BVAF_611Lipopolysaccharide heptosyltransferase I.
kdtA protein networkhttps://string-db.org/network/859654.BVAF_6123-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV( [...]
rpmG protein networkhttps://string-db.org/network/859654.BVAF_61350S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
rpmB protein networkhttps://string-db.org/network/859654.BVAF_61450S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
dut protein networkhttps://string-db.org/network/859654.BVAF_615Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intrace [...]
yicC protein networkhttps://string-db.org/network/859654.BVAF_616Conserved hypothetical protein.
BVAF_617 protein networkhttps://string-db.org/network/859654.BVAF_617marR family protein.
gmk protein networkhttps://string-db.org/network/859654.BVAF_618Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
rpoZ protein networkhttps://string-db.org/network/859654.BVAF_619Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
polA protein networkhttps://string-db.org/network/859654.BVAF_620DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
dsbA protein networkhttps://string-db.org/network/859654.BVAF_621Thiol:disulfide interchange protein dsbA.
ubiD protein networkhttps://string-db.org/network/859654.BVAF_6223-octaprenyl-4-hydroxybenzoate carboxy-lyase; Belongs to the UbiD family.
ubiB protein networkhttps://string-db.org/network/859654.BVAF_6232-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfa [...]
ubiE protein networkhttps://string-db.org/network/859654.BVAF_624Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-m [...]
rmuC protein networkhttps://string-db.org/network/859654.BVAF_625DNA recombination protein rmuC-like protein.
metE protein networkhttps://string-db.org/network/859654.BVAF_6265-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; [...]
rpoH protein networkhttps://string-db.org/network/859654.BVAF_627RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involve [...]
rsmD protein networkhttps://string-db.org/network/859654.BVAF_628Putative ribosomal RNA small subunit methyltransferase D; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfami [...]
pgi protein networkhttps://string-db.org/network/859654.BVAF_629Glucose-6-phosphate isomerase; Belongs to the GPI family.
metA protein networkhttps://string-db.org/network/859654.BVAF_630Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.